and recall/follow-up programs for newborns with heritable

conditions.
INTRODUCTION ON NEWBORN SCREENING
NSF- refers to Newborn Screening Facility.

NBSCC- refers to the Newborn Screening Continuity Clinic. A

facility responsible in counseling, treatment, monitoring and
follow-up of confirmed positive patients.

Rina
-7years old
-Normal growth
-Normal mentally
-Newborn Screening DONE
at birth thus treatment was
started early
-Diagnosed to have
Congenital Hypothyroidism
at first week of life
 NBS in the Philippines
June 1996 - Phil. Newborn Screening Project initiated by a group
of Pediatricians and Obstetricians to determine local incidence of
CH, CAH, PKU, GAL, HCY
 What is NBS?
 Process of collecting a few drops of blood from the newborn
onto an appropriate collection card and performing biochemical
testing for determining if the newborn has a heritable
condition.
Benjie
-14 years old  Is a public health program for the EARLY IDENTIFICATION of
-Stunted growth disorders that can lead to mental retardation and death.
-Severely mentally retarded
-Newborn Screening NOT
done  Program to screen for congenital and heritable disorders of ALL
-Diagnosed to have Filipino newborns.
Congenital Hypothyroidism
at the age of 12 years old
 In the Philippines, it is recognized as part of the standard
newborn care.
 NBS is part of the licensing and accreditation of DOH.
 NBS is a requirement for PHIC accreditation.
 NBS is part of the PHIC Newborn Care Package.

1997 – First Newborn Screening Center (NIH)  Expanded Newborn Screening?

1998 - Addition of G6PD def. in the panel
1999 - Inclusion of NBS in Child Health 2025 Framework of DOH
July 1999 - Creation of DOH Task Force on NBS
January 2000 - AO 1-A, s 2000 “Policies on the Nationwide
Implementation of Newborn Screening
Mid 2003 - Newborn Screening Bill was passed in the Congress
and Senate
December 2003 - DOH AO No.121, s 2003 “Strengthening
Implementation of the National Newborn Screening System”
January 2004 - Presidential Proclamation No 540, declaring the
First Week of October of each year as “National Newborn
Screening Awareness Week”
April 7, 2004 - Enactment of R.A. No. 9288 otherwise known as
the “Newborn Screening Act of 2004”
 Increases the number of disorders in the newborn screening
panel from six (6) to more than twenty-eight.
 Group of disorders under ENBS includes: endocrine disorders,
hemoglobinopathies, disorders of amino acid and organic
acid metabolism, disorders of fatty acid oxidation, disorders
of carbohydrate metabolism, disorders of biotin metabolism
and cystic fibrosis.
 What is the importance of NBS?
 Affected babies look normal at birth.
 One will never know that the baby has the disorder until the
onset of signs and symptoms which may already be irreversible
such as Mental Retardation and Death.
 It prevents complications if managed on time.
 NBS Golden Period

2012 - Addition of MSUD in the panel

2014 - Expanded Newborn Screening

January 5, 2019 – Full coverage of ENBS by PHIC

May 1, 2019 – Full implementation of ENBS

 Definition of Terms
NIHP- facility refers to the National Institutes of Health,
Philippines.

Newborn Screening Reference Center (NSRC) - central facility at

the NIHP that defines testing and follow-up protocols, maintains  ENBS
an external laboratory proficiency testing program, oversees the
national testing database and case registries, assists in training
activities in all aspects of the NBS program, oversees content of
educational materials, recommends establishment of NSCs and
acts as the Secretariat of the Advisory Committee on Newborn
Screening.

Newborn Screening Center (NSC)- facility equipped with a

newborn screening laboratory that complies with the standards
established by the NIHP, and provides all required laboratory tests
  Enhancement of Newborn Care Package (NCP)
NCP is a PhilHealth benefit package for essential health services of
the newborn during the first few days of life. It covers essential
newborn care, expanded newborn screening, and hearing
screening tests.
 What are the services included in the NCP?
 ESSENTIAL NEWBORN CARE
o Immediate drying of the baby
o Early skin to skin contact
o Timely cord clamping
o Non-separation of mother/baby for early
breastfeeding initiation
o Giving of eye prophylaxis
o Vitamin K administration
o Weighing of the baby
o First dose of Hepatitis B Vaccine
o First dose of BCG Vaccine
 NEWBORN SCREENING TEST
 NEWBORN HEARING SCREENING TEST
 What are the eligibility conditions to avail NCP?
Newborns are eligible for NCP if ALL of the following are met:
 Either of the parents are eligible to avail of the benefits
 Born in accredited facilities that perform deliveries, such
as hospitals and birthing homes; and
 Services were availed of upon delivery.
 Difference between old and enhanced NCP
NBS DISORDERS
1. Congenital Hypothyroidism (CH)
It results from lack or absence of thyroid hormone which is
essential for the physical and mental development of a child. If
the disorder is not detected and hormone replacement is not
initiated within two (2) weeks, the baby with CH may suffer from
growth and mental retardation.
Autosomal Recessive Inheritance
What causes CH?
Primary CH
Complete or partial absence of functional thyroid tissue
Abnormal location of the thyroid gland
Secondary CH or Tertiary CH
Defect in the part of the brain responsible for stimulating thyroid
hormone production
Clinical Manifestations of CH
Hypotonia, prolonged jaundice, inactive defecation, umbilical
hernia, pallor, coldness, hypothermia, edema, “rough” facial
features, enlarged tongue, rough, dry skin, open posterior
fontanelles
Late Manifestations of CH
Mental and growth retardation, delayed skeletal maturation,
delayed dental development and tooth eruption, delayed puberty

How to confirm CH?

 Thyroid function tests
 Low T3, Low T4, High TSH
 Thyroid Ultrasound
 Thyroid Scan

Treatment & Management

 Thyroid Hormone Replacement

2. Congenital Adrenal Hyperplasia (CAH)

Is an endocrine disorder that causes severe salt loss, dehydration

Expanded NBS
(A.O. No. 2014-0045, November 19, 2014) Aside from the 6
conditions in the present panel, ENBS will screen additional
disorders falling under various groups of conditions namely:
and abnormally high levels of male sex hormones in both boys
and girls. If not detected and treated early, babies with CAH may
die within 7 days.
Autosomal Recessive Inheritance

 Hemoglobinopathies
 Amino Acid Metabolism Disorders
 Organic Acid Metabolism Disorders
 Fatty Acid Oxidation Disorders
 Urea Cycle Defect
 Other group of disorders

Implementing Rules And Regulations

Republic Act No. 9288
Section 21: NBS Specimen Collection Kits
All hospitals, birthing facilities, Rural Health Units, Health
Centers and other collecting units throughout the country shall
have NBS Specimen Collection Kits AT ALL TIMES; Clinical Manifestations of CAH
Ambigous genitalia, adrenal crisis, poor suck, weakness, coma,
The cost of the NBS Specimen Collection Kits shall be based on vomiting, excessive urination, dehydration, irritability, seizures
the amount prescribed. and failure to thrive.
Late Manifestations of CAH
Precocious puberty (early sexual maturity and bone maturation,
accelerated growth during childhood, SHORT ADULT STATURE),
pubic hair growth, oily skin, body odor, dark skin color.
How to confirm CAH?
 17-OH progesterone –
Is a blood test that measures the amount of 17-OH progesterone.
This is a hormone produced by the adrenal glands and sex glands.
Treatment & Management
Assess hydration and give IVF accordingly
Monitor BP, blood glucose, plasma sodium, potassium & chloride
Hydrocortisone, Prednisone (cortisol replacement)
Fludnocortisone, Sodium Chloride (aldosterone replacement)
Abnormal genitalia–pediatric surgery if the baby is past 3 years old.
Psychological support for affected patients and families
Regular follow-up
3. Phenylketonuria (PKU)
Is a rare condition in which the baby cannot properly use one of
the building blocks of protein called phenylalanine. Excessive
accumulation of phenylalanine in the blood causes brain damage.
Excessive amounts of waste products of phenylalanine
(phenylketones) in the urine gives the urine a “mousy” odor.
Autosomal Recessive Inheritance
Clinical Manifestations of PKU
Vomiting, hyperactivity, seizures and hypertonia, musty or mousy
urine odor, light hair and skin color, seborrheic or eczematoid
rash, mental retardation
Late Manifestations of PKU
Mental and growth retardation, microcephaly, enamel hypoplasia
Poor Control of PKU
Significantly lower scores on measures of IQ, attention and
reaction time, poor cognitive functions and the presence of
behavioral difficulties
How to confirm PKU?
 Elevated serum Phenylalanine
 Low serum Tyrosine
 Classic signs and symptoms
 Gold Standard - Phenylalanine hydroxylase enzyme activity
Treatment & Management
 Low protein diet/Phenylalanine free milk/diet
 4 components of diet:
1. Complete avoidance of food containing high
amounts of phenylalanine
(High phenylalanine foods include soybeans, cheese,
nuts, seeds, beef, lamb, chicken, pork, fish, eggs,
dairy, beans, and whole grains)
2. Calculated intake of low protein/Phe natural food
3. Sufficient intake of fat and carbohydrates to fulfil
the energy requirements of the patient
4. Calculated intake of Phe free amino acid mixture
supplemented with vitamins, minerals and trace
elements as the main source of protein
 Regular follow-up & monitoring of blood & serum level
4. Galactosemia (GAL)
Is a metabolic disorder characterized by the body’s inability to use
galactose as a source of energy.
Clinical Manifestations of GAL
Normal at birth
Develop symptoms a few days to two weeks AFTER INITIATION OF
MILK FEEDINGS: poor feeding, vomiting, occasionally diarrhea,
jaundice, lethargy, weakness, coma, edema, ascites,
hepatomegaly, cataracts, mental retardation, cirrhosis of the liver
If untreated as high as 75% of infants will die
Fatal course ending in LIVER FAILURE
Neonatal death from SEPSIS, usually due to an Escherichia coli
infection
Treatment & Management
 Avoid milk & milk products
 Newborns-lactose free or galactose free formula– (Soy based
milk formula)
5. Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD Def.)
Is a condition where the body lacks the enzyme called G6PD.
Babies with this deficiency may have hemolytic anemia resulting
from exposure to oxidative substances found in drugs, foods and
chemicals.
Function of G6PD
Enzyme needed for the protection of RBC from oxidative
substances.
X-Linked Recessive:
Primarily affects males - Inherited from the mother
Females infrequently affected - Inherited from both parents
Clinical Manifestations of G6PD Def.
Most patients are asymptomatic if unexposed to oxidizing agents.
Results from stress factors such as oxidative drugs or chemicals,
infection, or ingestion of fava beans.
Acute hemolytic crisis:
Neonatal jaundice or kernicterus
Within 1 to 4 days of life
Infection- or drug-induced hemolysis
How to confirm G6PD Def.?
 Complete Blood Count to determine the level of anemia
 Increased serum bilirubin
 Measurement of the actual enzyme activity of G6PD
*Contact the nearest G6PD Center or G6PD Collecting Center
Treatment & Management
 AVOID the following:
Antibiotics: sulfonamides, sulfanilamide, sulfamethoxypyridazine,
sulfacetamide, sulfadimidine, sulfapyridine, sulfamerazine, and
sulfamethoxazole, nitrofurantoin, nalidixic acid, ciprofloxacin
niridazole, norfloxacin, chloramphenicol, phenazopyridine, and
Antimalarial: primaquine, chloroquine, pamaquine, pentaquine.
Substances: Acetanilid, Doxorubicin, Isobutyl nitrite, Naphthalene,
Phenylhydrazine, Pyridium, vitamin K analogs, methylene blue
Miscelleneous: fava beans, legumes, bitter melon (ampalaya), tonic
water, blueberry, menthol, camphor, herbs, gluten-free products,
black or green tea and extracts of red wine, henna.
 Oxygen and bedrest
 Blood transfusion
 Exchange transfusion
 6. Maple Syrup Urine Disease (MSUD)
Is a genetic metabolic disorder resulting from the defective
activity of the enzyme that breaks down branched-chain amino
acids. Accumulation of the amino acids is toxic to the brain. The
condition gets its name from the distinctive sweet odor of
affected infants' urine. The by product of isoleucine has a
characteristic sweet smell which gives the disorder its name.
Autosomal Recessive Inheritance
Figure 24.3 M.B., an 11-day-old infant with maple syrup
urine disease. He is shown in the characteristic
opisthotonic position. (The illustration was kindly provided
by Dr. Havelock Thompson of University of West Virginia.)
Clinical Manifestations of MSUD
12-24 hours after birth -> maple syrup odor in cerumen, increase
in BCAA levels and allo-isoleucine
2-3 days -> ketonuria, irritability and poor feeding
4-5 days -> lethargy, opisthotonus, sterotypical movements
7-10 days -> coma and respiratory failure
How to confirm MSUD?
 Increase leucine levels
Treatment & Management
 Relies heavily on dietary management
 Isoleucine-Leucine-Valine free milk
Treatment of Intercurrent Decompensations
 Situations that may induce protein catabolism
 Intercurrent infections
 Immunizations
 Trauma
 Anesthesia and surgery
A simple drop of blood
saves lives.
7. Thalassemias
Thalassemias are a group of blood disorders that affect the way
the body makes hemoglobin. Hemoglobin is a protein found in red
blood cells that carries oxygen throughout the body. It's made up
of alpha globin and beta globin.
Thalassemias are inherited conditions — they're carried in the
genes and passed on from parents to children. People who are
carriers of a thalassemia gene show no thalassemia symptoms
and might not know they're carriers. If both parents are carriers,
they can pass the disease to their kids. Thalassemias are not
contagious.
Types:
 Alpha thalassemia: when the body has a problem
producing alpha globin
 Beta thalassemia: when the body has a problem
producing beta globin
Clinical Manifestations of Thalassemia:
Fatigue, weakness, shortness of breath, pale appearance or
jaundice, irritability, deformities of the facial bones, slow growth,
a swollen abdomen, dark urine
Complications
Excess iron, bone deformities and broken bones, enlarged spleen,
infections, slower growth rates
How to confirm Thalassemia?
 CBC with MCV
 Hemoglobin Analysis (Capillary Electrophoresis)
 DNA Analysis
8. Disorders of Organic Acid Metabolism
What are organic acid disorders?
Body cannot metabolize certain amino acids and fats
Accumulation of organic acids in blood and urine
Serious potentially preventable effects on health and
development, including death
Symptoms
acute encephalopathy, vomiting, seizures, failure to thrive,
hypotonia, global developmental delay, metabolic acidosis,
ketosis, hyperammonemia, hypoglycemia, coma, death
Treatment
Low protein diet, special milk formula, supplementation
(carnitine, glycine, Vit B12)
9. Disorders of Fatty Acid Oxidation
What are fatty acid oxidation disorders?
Breakdown of fatty acids in mitochondria is an essential part of
body’s ability to produce energy
Disorder: inability to break down fatty acids
Symptoms
Decompensate with any catabolic stress, fever, fasting,
intercurrent illness, hypoketotic hypoglycemia, liver, muscle,
heart disease, lethargy, seizures, coma, sudden death (SIDS)
Treatment
Avoid prolonged fasting, low fat diet, some disorders require
carnitine supplementation
 10. Disorders of Urea Cycle
RA 9288 Article 3 Sec. 7. Refusal to be Tested
What are urea cycle disorders? A parent or legal guardian may refuse testing on the grounds of
religious beliefs, but shall acknowledge in writing their
Caused by a deficiency of any enzyme in the urea cycle
understanding that refusal for testing places their newborn at risk
for mental retardation or death of undiagnosed heritable
Symptoms conditions.
hyperammonemia ,acute encephalopathy, vomiting, seizures,
global developmental delay, coma, death A copy of this refusal documentation shall be made part of the
newborn’s medical record and refusal shall be indicated in the
Treatment national NBS database.
Limit protein, provide insufficient amino acids (arginine), disposal
*Secure 2 duly signed copies
of ammonia
STEP 2. Collecting NBS Samples
11. Biotin Responsive Disorders
This refers to the taking of blood sample from the newborn to be
What are biotin responsive disorders? used for the laboratory test.
Due to defects in recycling of biotin or lack of biotin
RA 9288 Sec 7. Performance of NBS
NBS shall be performed immediately after twenty four (24) hours
Symptoms of life but not later than three (3) days from complete delivery of
Metabolic ketoacidosis, organic aciduria, mild hyperammonemia, the newborn.
seizures, hypotonia, ataxia, developmental delay, vision problems,
hearing loss, cutaneous abnormalities Protocol on Collecting NBS Samples of Preterm, Low Birth
Weight and Sick Infants
Treatment  28th Day of Life- and twenty-eight (28) completed days
and not just 27 days and a few hours.
Biotin supplementation
 Preterm- < 37 completed weeks of gestation
 Low Birth Weight- <2000 grams at birth
12. Carnitine Uptake Defects
Memorandum 2018-006 Clarification on Protocol for Preterm,
 Defect in transport of carnitine (due to defect in sodium- Low Birth Weight and Sick Infants for Newborn Screening
dependednt organic cation transporter-1 enzyme)  Sick
 Can cause cardiomyopathy, liver complications, muscle
 Any baby admitted to the Neonatal Intensive Care
weakness
Unit (NICU) and requires intensive care (i.e.
 Illness or prolonged fasting can precipitate a metabolic intubated, CPAP, etc.)
crisis
 Some babies have abnormal results because their  The intensive care given to the baby may be due to
mothers have low free carnitine diagnosed/suspected illness and other
medical/surgical problems
Treatment:
Carnitine supplementation, avoid fasting **For babies who qualify the abovementioned definition of “sick”,
their DIAGNOSIS MUST BE WRITTEN AT THE BOTTOM PART OF
THE NBS FILTER CARD. If there is no diagnosis indicated on the
STEPS IN IMPLEMENTING NBS
filter card, the patient will be considered as NOT SICK.

 Not Sick

 Patients admitted to the NICU and on antibiotics

only for suspected sepsis and not needing intensive
care are NOT CONSIDERED “SICK” BABIES

 Patients admitted to the NICU and under

phototherapy for physiologic jaundice are NOT
CONSIDERED “SICK” BABIES

 Patients admitted to NICU for observation only and

not receiving intensive care are NOT CONSIDERED
“SICK” BABIES
STEP 1. Informing/Motivating the parents

 Inform parents or legal guardians about the nature and

benefits of NBS.
 Preferably during prenatal visits, mother’s classes, pre-
marriage counseling, home visits.
 Use posters; brochures; video if available.
 The following must be discussed:
 What is NBS?
 What disorders are being screened?
 Why NBS important?
 What are the benefits to the newborn?
 How is NBS performed?
 Cost of NBS

Who can collect the sample?
Collection of samples may be performed by any TRAINED health
workers: Physicians, Nurses, Medical technologists, Midwives
There should be a person designated to collect the blood sample.
Where do you collect the sample?
An area in the health facility designated for sample collection.
Reminders before Collection
 Accomplish the NBS filter card properly.
 Avoid contamination.
 Prevent mislabelling.
 Ensure complete and accurate data. Incomplete data leads to
delay in interpretation and release of results.
 The information requested on the filter card are important for
the interpretation of results. It is essential that card be
completely filled out.
 Contact information is very important for recall/follow-up of
positive screens.
Remember…
 Use only BLACK or BLUE ballpoint pen.
 DO NOT use a pencil.
 DO NOT use sign/gel pens.
 Write LEGIBLY in BLOCK LETTERS.
 Avoid ERASURES.
 Fill in the necessary information COMPLETELY.
What method to be used?
 Heel Prick Method-preferred method for collecting samples
 Venous blood maybe used only as an alternative when other
blood works are done
 Umbilical Blood is not recommended
Steps in Collecting Blood Samples
1. Prepare all the needed materials
(Fill out the filter card completely)
2. Warm the baby’s heel
 For sufficient & free flow of blood, hold the baby’s leg
lower than the head.
 Warm baby’s heel with warm towel for 3 minutes or
gentle rubbing of the baby’s heel.
3. Clean the puncture site
 Clean the area thoroughly with 70% isopropyl alcohol or
sterile water swab.
4. Dry the puncture site
 Wipe the prospective puncture site with a dry cotton ball
to prevent contamination of specimen with alcohol or
sterile water.
5. Prick the heel
 Make two punctures in quick succession on the lower
lateral borders of the heel.
 Do not puncture sites: arch of the foot, swollen area,
previously punctured area, fingers.
6. Wipe the first blood
 Wipe first drop of blood with a dry sterile cotton to avoid
contamination of blood samples.
7. Apply intermittent pressure
 DO NOT SQUEEZE the heel too hard as it may cause
interstitial fluid to leak and contaminate specimen.
 If blood flow slows down, release grip and wipe puncture
site again with DRY cotton to remove clot.
 Additional reminders:
 Avoid layering
 Do not use alcohol/ lotion prior to pricking
 Consider the space between the 2 pricks
 Maximize the use of the filter paper
8. Dry the samples
 Dry samples horizontally on drying rack at room temp
25deg C for at least 4 hours or completely dry.
 Dry on the drying rack in alternate manner.
 Avoid exposure to direct sunlight, artificial light or
heating instruments.
Are your samples ACCEPTABLE?
What is an acceptable sample?
 A sample taken MORE THAN 24 HOURS AFTER BIRTH
 A sample with demographic details that are COMPLETE
and CORRECT
 A sample with blood spots that are ADEQUATE FOR
TESTING
 A sample with blood spots that are COMPLETELY DRIED
(FOR A MINIMUM OF 4 HOURS) BEFORE SENDING OUT
 A sample with NO SERUM RINGS, RODENT OR INSECT
BITES
 A sample received in the Newborn Screening Center
Central Luzon NOT MORE THAN 14 DAYS AFTER
COLLECTION.
What is an UNSATISTACTORY SAMPLE?
 INSUFFICIENT
 CONTAMINATED
 OUT-DATED CARDS
 LATE
 <24 HOURS
 DATA ERASURES
 MISSING INFORMATION
 NO FEEDING
 NPO/TPN/SOY (Separated from Unsat)
 BLOOD TRANSFUSION (Separated from Unsat)
Recommendations to avoid the following:
Reasons for Repeat Sample
 Positive  Performing the test
(Slightly Elevated Result)
 Preterm
(<37 weeks)
 Low Birth Weight
(<2000 grams)
 Sick Infants
(NICU)
*Payment will be shouldered by parents
 Entering results into the database
STEP 3. Handling and Transporting NBS Samples  Analyzing the results
 Do not batch the samples. After 4-6 hours of proper
drying send the samples right away. STEP 5. Releasing of NBS Results
 Do not staple.
 Do not fold.  If elevated in one of the disorders:
 Physicians and/or NBS Coordinators in the involved NSF are
STEP 4. Performing NBS Test informed immediately after release of result from the
laboratory.
 Sorting of Samples at the Newborn Screening Center  Physicians or NBS Coordinators must inform the parents
immediately either for confirmatory or repeat sample
collection.
 If normal and G6PD deficient, results are released:
 7-21 days from date of receipt for emails
 14-21 days from date of receipt for courier
 3-4 weeks for postal mail
 Only abnormal results/elevated results are faxed to hospitals.
 There should be a designated person to handle the result.
 Numbering of Samples
STEP 6. Recalling of Patients

What to do with Patients with Positive Initial Screens?

 Recall patient -due to elevated and unsatisfactory results
 If slightly elevated, repeat screening
 If significantly elevated, confirmatory testing
 Check if confirmatory test is done

Follow-up results for confirmatory test

 Automated Punching of blood spots If positive – refer the patient to specialist
If negative – Inform AP and close the case

STEP 7. Managing, Referring and Monitoring of Positive Cases

 Prompt and appropriate management of positive cases is

essential in saving babies from the consequence of the
disorder

 Refer patients with positive screen to medical institutions with

available physicians or specialist capable of managing the
disorder.

RECALL AND FOLLOW-UP MANAGEMENT

 The success of a national program of Newborn Screening is
measured not only by the number of babies diagnosed but,
more so by the quality of life of the saved infants.

 The National Comprehensive Newborn Screening System

(NCNBSS) is a nationwide integrated system that includes the
diagnosis and management of babies with positive screens and
their follow-up.

 Each participating institutions should establish an effective

system in the recall of patients with elevated and rejected
samples.
 Designate a person to take charge of the recall.
 Define process in the recall of patient.
 Define strategies in the recall of patient.
 Establish proper documentation for prompt recall. (ex.
Narrative report )

PROMPT recall of patient would mean PROMPT management of

babies thereby saving them from possible mental retardation and
death. Never give up on any case!
*Should there be difficulty in recalling patients, you may seek the
assistance from the nearest RHU or DOH Regional Office.  Report discrepancy within the day of receipts otherwise, it
will mean the order was received in good order and
Short Term Follow-up Process condition.

Payment:
TERMS:
45 days- Non-Philhealth Accredited
60 days- Philhealth Accredited

Term of payment starts from the BILLING STATEMENT DATE.

Partial payment is not accepted.

MODES:
 Walk-in or Bank Transfers

Banco De Oro Account Number: 1460040765

Account Name: Angeles University Foundation
Medical Center, Inc.
Landbank Account Number: 1522-222-000
Account Name: AUFMC,INC

Where are the confirmatory centers? How much? PNB Account Number: 437600500039
Account Name: AUF Medical Center, Inc.
Please see separate sheet.
Sending of Samples to NSC-CL:
Who are the specialists? LBC, DHL, AIR 21, ABest, 2Go, Stat Delivery

Protocol:
 Use the courier’s SMALL POUCH for NBS samples.
 Answer all inquiries regarding contact details and
address.
 Remember proper way of packaging samples.
 The NBS Coordinator should personally secure the
samples in the pouch and fill in required information.
 Fill-out the airway bill for shipper’s detail and NSC-CL is
the consignee. DO NOT FORGET TO WRITE THE ACCOUNT
NUMBER of NSC-CL and tick the box “BILL CONSIGNEE”.

ADMINISTRATIVE MECHANICS Replacement Matrix

Modes of Ordering:

Delivery:
COURIER REPORTING OF NBS PROGRAM
Allow 3-7 working days from receipt of PO or 10 working days if
facility is outside the service area of the courier.  Use the recommended form for reporting.
 Complete the details asked in the form for necessary updates.
*Note: Notify NSC if otherwise.  Follow instructions written in the form.

PICK UP Submission of Report

In order that all reports from Newborn Screening Facilities in

Central Luzon be recorded, Newborn Screening Coordinators shall
submit the NBS Monthly Census Reports to CLCHD via Google
Form.
 The original sales invoice will accompany the ordered kits
along with official receipts of payments.
Newborn Screening Monthly Census Reports shall be submitted
on or before the 5th day of the following month via Google Form.
(https://tinyurl.com/NBSReports) Example: June report will be
submitted on or before 5th of July.

Newborn Screening Center Central Luzon

Telephone : (045) 624-6571
Telefax : (045) 624-6503
Office Mobile : (0917) 820-8118
(0908) 820-2155
(0908) 820-0867
Email : nscaufmc@gmail.com

Department of Health-CLCHD
Contact Persons: Divina Rae Bermudez, NBS Medical Coordinator
Madeline Gayle L. Tayag, NBS Nurse Coordinator
Jelly Anne C. Quinajon, NBS Nurse Coordinator
Contact Numbers:
0932-743-6736 – Ms. Tayag
0933-269-6354 – Ms. Quinajon

-END-