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Stroke volume optimization

% Change in stroke volume (∆SV) is a sensitive method for


assessing preload responsiveness on all patients.

Monitor stroke volume

200 – 250 ml fluid


challenge over 5 –10 min* Yes

Yes No
SV increase >10% SV reduction >10%

No Monitor stroke volume for


clinical signs of fluid loss

Oesophageal Doppler-guided fluid management during major surgery: reducing


postoperative complications and bed days. NHS Technology Adoption Centre.
January 2012.

*A passive leg raising maneuver over 1-2 min. can also be used as a fluid challenge
Monnet X, Teboul JL. Passive Leg Raising. Intensive Care Med. 2008 Apr; 34 (4): 659-63.

Frank-Starling curve
Relationship between preload status and
fluid-induced increases in stroke volume.
Stroke volume Discontinue Increasing SV with fluid until
Continue fluid
fluid the plateau of the Frank-Starling
Continue ∆SV < 10% curve is reached has been shown
fluid ∆SV > 10% to improve the outcome of
high-risk surgery patients.
∆SV > 10% Lopes MR, et al. Goal-directed
∆P = fluid-induced increase in preload fluid management based on pulse
pressure variation monitoring
during high-risk surgery: a pilot
randomized controlled trial.
Preload Critical Care. 2007 Oct;11(5):R100.
Parameter Normal Range
CO (cardiac output) 4.0 - 8.0 L/min
CI (cardiac index) 2.5 - 4.0 L/min/m2
SV (stroke volume) 60 - 100 mL/beat
SVI (stroke volume index) 33 - 47 mL/beat/m2
SVR (systemic vascular resistance) 800 - 1200 dyn-s/cm5
SVRI (systemic vascular resistance index) 1970-2390 dyn-s/cm5/m2
SVV (stroke volume variation) <13%

Stroke volume variation optimization


Stroke volume variation (SVV) is a reliable indicator of preload
responsiveness on control-ventilated patients.

Not meeting perfusion requirements

Volume responsive SVV>13%

Yes No

Volume SVI normal SVI low SVI high


challenge

Pressor Inotrope Diuretic

McGee WT, A Simple Physiologic Algorithm for Managing Hemodynamics Using


Stroke Volume and Stroke Volume Variation: Physiologic Optimization Program.
J Intensive Care Med. 2009 Nov; 24 (6): 352-60.

Stroke Volume Variation (on control-ventilated patients)


Variation in arterial pulsations caused by heart-lung changes during
positive pressure ventilation.
25 25

20
20
SVmax Airway
Airway pressure
pressure
SVmax 15
15
SVmin
SVmin Arterial
Arterial pressure
pressure
10 10

5
5
SVmax-SVmin
SVmax-SVmin
0 %SVV%SVV
= =
0
SVmean
SVmean
-5 -5
0 0
1000 1000
2000 2000
3000 3000
4000 4000
5000 5000
6000 6000
7000 7000

Expiration
Expiration Inspiration
Inspiration
controlled
controlled ventilation
ventilation controlled
controlled ventilation
ventilation

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