Uchino Et Al 2008 Prevalence of Dry Eye Disease Among Japanese Visual Display Terminal Users - Ophthalmology

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References ORIGINAL ARTICLE | VOLUME 115, ISSUE 11, P1982-1988, NOVEMBER 2008 Download Full Issue

Article info
Prevalence of Dry Eye Disease among Japanese Visual
Display Terminal Users
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Miki Uchino, MD   • Debra A. Schaumberg, ScD, MPH • Murat Dogru, MD • ...


Toshihiko Satoh, MD, MPH • Toru Takebayashi, MD, MPH • Kazuo Tsubota, MD • Show all authors

Published: August 19, 2008 • DOI: https://doi.org/10.1016/j.ophtha.2008.06.022 PlumX Metrics

Objective
To determine the prevalence of dry eye disease (DED) and risk factors among young and middle-aged Japanese office
workers using visual display terminals (VDTs).

Design
Cross-sectional prevalence survey.

Participants
Four thousand three hundred ninety-three Japanese young and middle-aged office workers using VDTs.

Intervention
Office workers completed questionnaires sent by e-mail designed to detect dry eye diagnosis and risk factors.

Main Outcome Measures


Clinically diagnosed DED was defined as the presence of a previous clinical diagnosis of DED by dry eye specialists or
severe symptoms of DED (both dryness and irritation constantly or often). Current symptoms of DED and possible risk
factors such as age, duration of VDT use, type of VDT work, environmental factors, presence of systemic diseases,  
systemic medicine use, smoking history, and contact lens (CL) use were the main outcome measures. We used logistic
regression to examine associations between DED and other demographic factors.

Results
Of the 4393 office workers, 3549 (80.1%) completed the questionnaire. Clinically diagnosed DED was present in 266
(10.1%) of 2640 male subjects and in 195 (21.5%) of 909 female subjects. Severe symptoms of DED were observed in 711
male and in 436 female participants. More than 4 hours of VDT use was associated with an increased risk of DED (odds
ratio [OR], 1.68; 95% confidence interval [CI], 1.40–2.02). In addition, CL use (OR, 3.91; 95% CI, 3.37–4.53) increased the
risk of severe dry eye symptoms.

Conclusions
Dry eye disease leading to a clinical diagnosis or severe symptoms is prevalent among young and middle-aged Japanese
office workers. The condition is more prevalent among females, CL wearers, and prolonged VDT users. Relevant measures
directed against the modifiable risks could provide a positive impact on public health and quality of life of office workers.

Financial Disclosure(s)
The authors have no proprietary or commercial interest in any materials discussed in this article.

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Article info
Publication history
Published online: August 19, 2008
Accepted: June 18, 2008
Received in revised form: June 18, 2008
Received: March 6, 2008
Available online: August 16, 2008.

Footnotes
Manuscript no. 2008-298.

Financial Disclosure(s): The authors have no proprietary interest in any of the products mentioned in this paper.

Supported by the Japan Ministry of Health, Labour and Welfare, Tokyo, Japan (grant no.: H17-025).

Identification
DOI: https://doi.org/10.1016/j.ophtha.2008.06.022

Copyright
© 2008 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

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