Histopath Unit 1

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5

The Medical
Technologist’s Prayer
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WELCOME EVERYONE TO !!!

Prof. Mark Jefferson S. Merto, RMT


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Part I : General Pathology


Part II: Histopathologic Techniques
Part III: Cytologic Techniques
General Pathology
Introduction
Review of Normal Histology
Terminologies
Branches of Pathology
Diseases
Etiology
Pathogenesis
Morphologic changes and Functional
Derangements
Clinical Significance
General Pathology

At the end of this unit, the student is able to:

1- Discuss the Normal Histology (recall)


2- Describe the Normal Structure of Cells and Tissues
3- Define different Terms associated with Pathology
4- Explain the Pathophysiology of Disease Process
5- Define the Division and Scope of Pathology
6- Enumerate the Biologic Causes of Disease
7- Differentiate between the Structure of Normal and
Abnormal Cells and Tissues
General Pathology

KEY TERMINOLOGIES
 HISTOLOGY
 PATHOLOGY  HYPERTROPHY
 HISTOPATHOLOGY  ATROPHY
 DYSTROPHY
 HISTOPATHOLOGIST  AGENESIA
 HISTOTECHNOLOGIST  APLASIA
 HYPOPLASIA
 HYPERPLASIA
 BIOPSY  DYSPLASIA
 FNAB  ATRESIA
 AUTOPSY  NECROSIS
 APOPTOSIS
 KARYOLYSIS
 KARYORRHEXIS
 PYKNOSIS
 AUTOLYSIS
General Pathology

• The term Histology was coined in 1819 by


Karl Mayer, who combined the two Greek
words histos (tissues) and logos (study).
General Pathology

CELL
• is the fundamental structural and functional unit of
the body.
General Pathology

TISSUE
• A tissue is a group of cells, in close proximity, organized
to perform one or more specific functions.
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Pathology is a branch of medical science primarily concerning


the cause, origin and nature of disease. It involves the
examination of tissues, organs, bodily fluids and autopsies in
order to study and diagnose disease
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Histopathology is the diagnosis and study of diseases of the tissues, and


involves examining tissues and/or cells under a microscope. Histopathologists
are responsible for making tissue diagnoses and helping clinicians manage a
patient's care.
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FINE NEEDLE ASPIRATION BIOPSY (FNAB)


is a simple procedure that involves passing a thin needle
through the skin to sample fluid or tissue from a cyst or solid
mass,
General Pathology

An EXCISIONAL BIOPSY is a medical test in which the whole


lesion or mass is removed and tested.
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