Insulin therapy

Dicovered in 1921
Extracted from pigs and cows
Recently=DNA recombonent technology
THE ONLY DRUG WITH NO MAXIMUM DOSE
It’s the only pure anabolic hormone
 types
Soluble=clear=short acting=regular=unmodified
Insoluble=cloudy=intermediate=depot=modified
Addition of protamine +zinc=isophane or NPH insulin
Addition of zinc ions=lente
Available in 100units/ml
Roots=IV+IM+SC+INHALOR+INTRAPERITONEAL+CONTINEOUS
S.C INSULIN INFUSION(SCII)+oral(?????)
WARMING+EXCERSICE+LOCAL MASSAGE=INCREASE ITS
ABSORPTION
ANT ABD. WALL=UPPER ARMS=OUTER THIGHS=BUTTOCKS
SHORT+LONG ACTING INJ.15-30 MIN BEFORE MEAL
RAPID ACTING INJ. IMMEDIATELY
REMOVED BY LIVER+KID
T ½=10 MIN.
SIDE
EFFECTS=HYPOG.+LIPODYSTROPHY+WT.GAIN+ALLERGY(RARE)+P
ERIPHERAL EDEMA+AUTO.AB
INJ. SITES
REGULAR INJ.
PEN
PUMP
INHALOR
INHALORS
INJ. TECH
LIPODYSTROPHY
LIPODYSTROPHY
THANK YOU