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1. Match column I with column II:
Column I Column II
(i) GLUT – 4 (a) Abrin
(ii) Toxins (b) Alkaloid
(iii) Codeine (c) Drug
(iv) Curcumin (d) Enables glucose transport

Select the correct answer from the options given below:

(i) (ii) (iii) (iv)
1) (c) (a) (d) (b)
2) (d) (a) (c) (b)
3) (d) (a) (b) (c)
4) (b) (c) (a) (d)

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2. How many number of nitrogenous bases are present in half a turn of a
DNA molecule?
1) 10 Bases
2) 20 Bases
3) 5 Bases
4) None of these

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3. Given below are two statements:
Statement I: The building block for all nucleic acid, is nucleoside.
Statement II: A nucleotide has 4 chemically distinct components, a heterocyclic
compound, a monosaccharide, a phosphate group and a polysaccharide.
In the light of the above statements, choose the most appropriate answer from
the options given below:
(1) Both Statement I and Statement II are correct
(2) Both Statement I and Statement II are incorrect
(3) Statement I is correct but Statement II is incorrect
(4) Statement I is incorrect but Statement II is correct

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4. Adenine pairs with:
1) Guanine
2) Thiamine
3) Uracil
4) Both (2) & (3)

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 5. Given below are two statements:
Statement I: The skeletal heterocyclic and homocyclic rings are called purines
and pyrimidines respectively.
Statement II: The sugars found in polynucleotides is a monosaccharide pentose
sugar
In the light of the above statements, choose the most appropriate answer
from the options given below:
(1) Both Statement I and Statement II are correct
(2) Both Statement I and Statement II are incorrect
(3) Statement I is correct but Statement II is incorrect
(4) Statement I is incorrect but Statement II is correct

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6. Which bond is formed when the carboxylic group of one amino acid
reacts with the amino group of the next amino acid with the
elimination of a water moiety?
1) Glycosidic Bond
2) Peptide Bond
3) Sulphide Bond
4) Phosphodiester Bond

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7. Which type of bond is present between a phosphate and hydroxyl group of
sugar in a nucleotide?
1) Glycosidic bond
2) Peptide bond
3) Ether bond
4) Phosphoester bond

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 8. Given below are two statements:
Statement I: The backbone of DNA is formed by sugar-phosphate-sugar chain.
Statement II: The nitrogenous bases are projected perpendicular to this
backbone and face outside.
In the light of the above statements, choose the most appropriate answer
from the options given below:
(1) Both Statement I and Statement II are correct
(2) Both Statement I and Statement II are incorrect
(3) Statement I is correct but Statement II is incorrect
(4) Statement I is incorrect but Statement II is correct

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 9. Given below are two statements:
Statement I: The amount of Adenine will always be equal to the amount of
Guanine.
Statement II: There are two hydrogen bonds between Adenine and Guanine and
three hydrogen bonds between Thymine and Cytosine.
In the light of the above statements, choose the most appropriate answer
from the options given below:
(1) Both Statement I and Statement II are correct
(2) Both Statement I and Statement II are incorrect
(3) Statement I is correct but Statement II is incorrect
(4) Statement I is incorrect but Statement II is correct

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10. In a DNA Double Helix, at each step of ascent, the strand turns _____.
1) 3.4 nm
2) 0.34 Å
3) 360⁰
4) 36⁰

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11. Which form of DNA has pitch of 34 Å and the rise per base pair is 3.4 Å?
1) B – DNA
2) A – DNA
3) Z – DNA
4) C – DNA

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12. Given below are two statements:
Statement I: In the whole of the biosphere all proteins are not enzymes but all
enzymes are strictly proteins.
Statement II: No organic molecule other than protein can behave as a
biocatalyst.
In the light of the above statements, choose the correct answer from the
options given below.
1) Both statements are correct & Statement I is the Reason for Statement II.
2) Both statements are correct & Statement II is the reason for Statement I.
3) Both the statements are correct & independent.
4) Both the statements are incorrect.

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13. Given below are two statements:
Statement I: All the biomolecules are constantly being changed into some
other biomolecules and also made from some other biomolecules.
Statement II: All the chemical reactions through which this breaking and
making occur constantly, are together called metabolism.
In the light of the above statements, choose the most appropriate
answer from the options given below:
(1) Both Statement I and Statement II are correct
(2) Both Statement I and Statement II are incorrect
(3) Statement I is correct but Statement II is incorrect
(4) Statement I is incorrect but Statement II is correct

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14. Given below are two statements:
Statement I: Majority of the metabolic reactions occur in isolation and are
always independent of each other.
Statement II: There is no uncatalyzed metabolic conversion in living systems.
In the light of the above statements, choose the most appropriate answer
from the options given below:
(1) Both Statement I and Statement II are correct
(2) Both Statement I and Statement II are incorrect
(3) Statement I is correct but Statement II is incorrect
(4) Statement I is incorrect but Statement II is correct

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15. Given below are two statements one is labelled as Assertion (A) & the
other is labelled as Reason (R).
Assertion: The formation of lactic acid from glucose in our skeletal muscle is
an example of catabolism.
Reason: The above case constitutes a biosynthetic pathway.
In the light of the above statements, choose the correct answer from the
options given below.
1) Both (A) & (R) are correct & (R) is the correct explanation of (A).
2) Both (A) & (R) are correct but (R) is not the correct explanation of (A).
3) (A) is correct but (R) is incorrect.
4) (A) is incorrect but (R) is correct.

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16. The blood concentration of hormones in a normal healthy individual
would be in:
1) Nanograms/L
2) Nanograms/mL
3) mM/L
4) mM/mL

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17. Given below are two statements one is labelled as Assertion (A) & the
other is labelled as Reason (R).
Assertion: Living organisms can not afford to attain a steady-state.
Reason: Steady-state is a non-equilibrium state.
In the light of the above statements, choose the correct answer from the
options given below.
1) Both (A) & (R) are correct & (R) is the correct explanation of (A).
2) Both (A) & (R) are correct but (R) is not the correct explanation of (A).
3) (A) is correct but (R) is incorrect.
4) (A) is incorrect but (R) is correct.

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18. Given below are two statements:
Statement I: Living process is a constant effort to prevent falling into
equilibrium.
Statement II: This can be achieved by energy input.
In the light of the above statements, choose the most appropriate answer
from the options given below:
(1) Both Statement I and Statement II are correct.
(2) Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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19. Given below are two statements one is labelled as Assertion (A) & the
other is labelled as Reason (R).
Assertion: Catalyzed reactions proceed at rates vastly higher than that of
uncatalyzed ones.
Reason: The rates of physical and chemical processes are influenced by
temperature among other factors.
In the light of the above statements, choose the correct answer from the
options given below.
1) Both (A) & (R) are correct & (R) is the correct explanation of (A).
2) Both (A) & (R) are correct but (R) is not the correct explanation of (A).
3) (A) is correct but (R) is incorrect.
4) (A) is incorrect but (R) is correct.

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20. How many H2CO3 molecules will be obtained in an hour from the
reaction given below if the reaction is not catalyzed by any enzyme?

1) 600000 molecules in an hour.

2) 300 molecules in an hour.
3) 100 molecules in an hour.
4) 200 molecules in an hour.

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21. Given below are two statements one is labelled as Assertion (A) & the
other is labelled as Reason (R).
Assertion: No enzyme is found to be active at high temperatures till date.
Reason: Enzymes generally functions in a narrow range of temperature & pH.
In the light of the above statements, choose the correct answer from the
options given below.
1) Both (A) & (R) are correct & (R) is the correct explanation of (A).
2) Both (A) & (R) are correct but (R) is not the correct explanation of (A).
3) (A) is correct but (R) is incorrect.
4) (A) is incorrect but (R) is correct.

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22. During the state where substrate is bound to the enzyme, a new
unstable structure of the substrate is formed which is called:
1) The active state
2) The transient state
3) The product state
4) The resting state

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23. Given below are two statements:
Statement I: In an enzyme catalysed chemical reaction, all other intermediate
structural states between the structure of substrate and the structure of product
are unstable.
Statement II: Stability is related to energy status of the molecule or the structure.
In the light of the above statements, choose the most appropriate answer from
the options given below:
(1) Both Statement I and Statement II are correct.
(2) Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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24. A general rule of thumb is that rate of a chemical reaction doubles or
decreases by ___ for every ___ change in either direction.

1) 1/4 ; 10⁰
2) 1/2 ; 20⁰
3) 1/2 ; 10⁰
4) 1/3 ; 10⁰

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25. Given below are two statements:
Statement I: Enzymes show highest activity below the optimum pH.
Statement II: A significant increase in temperature will preserve the enzyme
in a temporarily inactive state.
In the light of the above statements, choose the most appropriate answer
from the options given below:
(1) Both Statement I and Statement II are correct.
(2) Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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26. Given below are two statements one is labelled as Assertion (A) & the
other is labelled as Reason (R).
Assertion: Velocity of enzymatic reaction increases with increase in substrate
concentration, ultimately it reaches Vmax which is not exceeded by any further
rise in concentration of the substrate.
Reason: Enzyme molecules are fewer than the substrate molecules & after
saturation no free enzyme molecule are left to bind with additional substrate
molecule.
In the light of the above statements, choose the correct answer from the
options given below.
1) Both (A) & (R) are correct & (R) is the correct explanation of (A).
2) Both (A) & (R) are correct but (R) is not the correct explanation of (A).
3) (A) is correct but (R) is incorrect.
4) (A) is incorrect but (R) is correct.
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27. The process in which binding of a chemical shuts off the enzyme activity
is called:
1) Competition
2) Activation
3) Inhibition
4) Degeneration

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28. Given below are two statements one is labelled as Assertion (A) & the
other is labelled as Reason (R).
Assertion: In competitive inhibition, the inhibitor competes with the substrate
molecule for the substrate binding site of the enzyme.
Reason: The chemical formula of the competitive inhibitor closely resembles
with the substrate molecule.
In the light of the above statements, choose the correct answer from the
options given below.
1) Both (A) & (R) are correct & (R) is the correct explanation of (A).
2) Both (A) & (R) are correct but (R) is not the correct explanation of (A).
3) (A) is correct but (R) is incorrect.
4) (A) is incorrect but (R) is correct.

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29. Succinate closely resembles in structure with which of the following
chemicals ?
1) Pyruvate
2) Succinic dehydrogenase
3) Ubiquinone
4) Malonate

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30. Given below are two statements:
Statement I: Some competitive inhibitors are often used in the control of
bacterial pathogens.
Statement II: Collagen is the most abundant protein in plant world.
In the light of the above statements, choose the most appropriate answer
from the options given below:
(1) Both Statement I and Statement II are correct.
(2) Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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 31. Given below are two statements:
Statement I: Some proteinaceous enzymes carry hereditary information
which is passed on from parental generation to progeny.
Statement II: Ribozymes are nucleic acids with catalytic power.
In the light of the above statements, choose the most appropriate answer
from the options given below:
(1) Both Statement I and Statement II are correct.
(2) Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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32. Enzymes are divided into ___ classes each with 4-13 subclasses and
named accordingly by a ___ digit number.
1) 4 ; 3
2) 4 ; 6
3) 6 ; 2
4) 6 ; 4

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33. Which enzyme catalyse the linking together of P-O bond?
1) Lyases
2) Ligase
3) Isomerase
4) Dehydrogenase

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34. Which of the following enzyme is responsible for catalyzing the
oxidoreduction between two substrates?
1) Hydrolase
2) Transferase
3) Dehydrogenase
4) None of these

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 35. Given below are two statements:
Statement I: Co-factors are bound to the enzyme to make the enzyme
catalytically active.
Statement II: These co-factors are non-protein constituents.
In the light of the above statements, choose the most appropriate answer
from the options given below:
(1) Both Statement I and Statement II are correct.
(2) Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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36. In the instances where a non protein part binds to an
enzyme to make it catalytically active, the proteinaceous
portion of the enzyme is called as:
1) Coenzyme
2) Apoenzyme
3) Co-factor
4) Holoenzyme

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37. Given below are two statements:
Statement I: Three kinds of coenzymes can be identified as; prosthetic
groups, co-factors and metal ions.
Statement II: The prosthetic groups are inorganic compounds.
In the light of the above statements, choose the most appropriate answer
from the options given below:
(1) Both Statement I and Statement II are correct.
(2) Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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38. Which of the following is the prosthetic group and part of
the active site of an enzyme which catalyzes the breakdown of
hydrogen peroxide to water and oxygen?
1) Catalase
2) Peroxidase
3) Haem
4) Both 1 and 2

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39. Which of the following pyrimidine is found in both RNA and DNA?
1) Cytosine
2) Adenine
3) Guanine
4) Thymine

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40. What is Michaelis Menten Constant (Km)?
1) Maximum rate of enzymatic activity.
2) Substrate concentration at which the reaction attains half of its maximum
velocity.
3) The rate of a metabolic reaction.
4) Substrate concentration at which the reaction attains its maximum velocity.

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41. Given below are two statements:
Statement I: Tertiary structure is essential for the activity of a
proteinaceous enzyme.
Statement II: A cofactor is a type of coenzyme.
In the light of the above statements, choose the most appropriate
answer from the options given below:
(1) Both Statement I and Statement II are correct.
(2) Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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42. Given below are two statements:
Statement I: In a DNA molecule two strands of polynucleotides
are parallel and complimentary to each other.
Statement II: The backbone of DNA is formed by sugar- phosphate
- nitrogenous base chain.
In the light of the above statements, choose the most appropriate
answer from the options given below:
(1) Both Statement I and Statement II are correct.
(2) Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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43. Given below are two statements:
Statement I: Starch is the reserved food material in animals.
Statement II: Glycosidic bond is formed by dehydration
In the light of the above statements, choose the most appropriate
answer from the options given below:
(1) Both Statement I and Statement II are correct.
(2) Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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 44. Given below are two statements:
Statement I: The hexose sugar present in RNA is ribose.
Statement II: Glycogen, lactose and starch are Polysaccharides.
In the light of the above statements, choose the most
appropriate answer from the options given below:
(1)Both Statement I and Statement II are correct.
(2)Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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45. Given below are two statements one is labelled as Assertion (A) & the
other is labelled as Reason (R).
Assertion: Starch when reacts with Iodine, gives blue colour.
Reason: Starch can hold I2 molecules in its pleated structure.
In the light of the above statements, choose the correct answer from the
options given below.
1) Both (A) & (R) are correct & (R) is the correct explanation of (A).
2) Both (A) & (R) are correct but (R) is not the correct explanation of (A).
3) (A) is correct but (R) is incorrect.
4) (A) is incorrect but (R) is correct.

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46. Given below are two statements:
Statement I: Adenine and Guanine are substituted purines.
Statement II: Nucleic acids exhibit a wide variety of
secondary structures.
In the light of the above statements, choose the most
appropriate answer from the options given below:
(1)Both Statement I and Statement II are correct.
(2)Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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47. Given below are two statements:
Statement I: Valine is a neutral amino acid.
Statement II: Sucrose is a disaccharide.
In the light of the above statements, choose the most
appropriate answer from the options given below:
(1)Both Statement I and Statement II are correct.
(2)Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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48. Given below are two statements:
Statement I: All the chemical reactions in a living organism are
called Turn over.
Statement II: The most important form of energy currency in living
systems is the bond energy in a chemical call ATP.
In the light of the above statements, choose the most
appropriate answer from the options given below:
(1)Both Statement I and Statement II are correct.
(2)Both Statement I and Statement II are incorrect.
(3) Statement I is correct but Statement II is incorrect.
(4) Statement I is incorrect but Statement II is correct.

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49. Holoenzyme consists of a non protein constituent called ___
and a protein portion called the___.
1) Apoenzyme; Coenzyme
2) Coenzyme; Prosthetic group
3) Prosthetic group; Coenzyme
4) Coenzyme; Apoenzyme

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50. Which of the following is a cofactor for the proteolytic enzyme
carboxypeptidase?
1) Iron
2) Cobalt
3) Zinc
4) None of these

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