SpecPlex® Gloss

ONE-STOP
•
SHINING Solution
Strengthen Skin’s ECM • Create Glossy skin, Add luster to skin
(NOI=80%)
• Enhance your natural glow
• Relieve skin stress
Make skin multi-active • Caring skin highlighter
Spec Chem Group·Application Center
Doris T Wang
 CONTENTS

 SpecPlex® Gloss：keep up with customers’ requirements

 What is SpecPlex® Gloss

 What does SpecPlex® Gloss bring to your skin

 Technical Supporting Data of SpecPlex® Gloss

 User Guide of SpecPlex® Gloss

SpecPlex ® Gloss：
keep up with customers’requirements

Skin dullness Rough and uneven skin Melanin deposition Wrinkled, Lifeless skin
Brightening luster Smoothening skin Uneven pigmentation, Energetic Skin
SpecPlex® Gloss：
keep up with customers’ requirements

Market Trends: Adorned beauty convert into natural beauty

 Wellness-Inspired Beauty Items, enjoy both its rejuvenating and skin-

nourishing effects, both externally and internally.

 Advocate natural and healthy beautifulness, naked/nude & tone-up Skin.

 Natural Look-Loving, dewy, “No Makeup” look style.

 Enhance skin’s regulating capacity, increased preference for curative skin

remedies

 Inclusivity of all skin types & colors

SpecPlex® Gloss：
keep up with customers’ requirements

Which one do you think is much more glossy?

And why? Except for inherent chromatic difference

The direction of light reflected from an object depends on its inherent nature.
SpecPlex® Gloss：
keep up with customers’ requirements

Beauty is not only from outside in but also from inside out ！

• Epithelium is one of the four

basic types of animal tissue,
outside
along with connective tissue,
muscle tissue and nervous
tissue. It is a thin, continuous,
protective layer of cells.

• An example is the epidermis,

the outermost layer of the skin.

• The epidermis is the outermost

of the three layers that make
up the skin, the epidermis
layer provides a barrier to
infection from environmental
pathogens and regulates the
amount of water released
inside from the body into the
atmosphere through
transepidermal water loss.
SpecPlex® Gloss：
keep up with customers’ requirements

Three main layers: The topmost layer (epidermis), the middle layer (dermis),
and the bottom layer (hypodermis).

The outermost part of the epidermis is the stratum corneum, or the skin
barrier. Scientists often liken the stratum corneum’s structure to being like
a brick wall. In this analogy, the skin cells are the bricks. Everything else—
including the skin barrier—is the mortar that holds it all together. This
mortar contains essential nutrients. Together, these compounds are referred
to as skin’s "natural moisturizing factor," because they help keep the deeper
layers of skin hydrated and nourished.

Source: Kiehls-skin care advice

SpecPlex® Gloss：
keep up with customers’ requirements

Skin Barrier Anti-pollution Protect Skin from External Stressors Water retention Skin smoothness Normal keratinization

Radiance/Gloss Brightening Youth/Smoothness without sags and crests Healthy/Natural-looking Plumping & Elastic
What is SpecPlex® Gloss
What Causes Skin Barrier Dysfunction?
The most significant factors that can impair barrier function are those
you likely already know;
1. like UV radiation, smoking, and chronic exposure to pollution.
2. Physical damage—like that incurred from over-exfoliating—can also
affect your skin barrier’s health,
3. Lifestyle factors, like your stress levels and how much sleep you get.
4. Inherent Aging
Any internal or external stressor that results in visible skin changes is
likely capable of disrupting or damaging your skin barrier.
6-Step Routine
1. Gentlely Remove aging cutin/horniness
without stripping away any of its essential
moisture
2. Soothe skin with moistures and nutritions
3. Scavenging stressful & sensitizing factors
4. Lock & replump essential ECM substance
5. Prevent the synthesis of melanin
6. Eliminate the pigmentation deposit
What is SpecPlex® Gloss
The epidermal extracellular matrix is a basement membrane, whereas the dermal ECM comprises fibrillar collagens and associated proteins. In skin, cell ECM
interactions influence normal homeostasis, aging, wound healing, and disease.

• Proteoglycan
• Polysaccharide Molecule

• Collagen Fiber
• Collagen Molecule

• Fibronectin
• Integrin

In biology, the extracellular matrix

(ECM) is a three dimensional network
of extracellular macromolecules, such
as collagen, enzymes, and
glycoproteins, that provide structural
and biochemical support to
surrounding cells.
What is SpecPlex® Gloss

SpecPlex® Gloss endows skin beauty not only from outside in but also from inside out ！

SpecPlex® Gloss is a water-soluble compound product with six skin brightening/lightening

ingredients. It can smooth skin through remove dead horn cells reduce the production of
melanin, removing the formed pigment and reducing pigmentation; it contains the
ingredients strenthening extracellular matrix (ECM) though promoting the production of
collagens and glycosaminoglycans (GAGs); Thus, it has the function of plumping/enriching
skin texture and lightening skin tone, delaying aging, moisturizing and nourishing skin, etc.
The six active ingredients cooperate with each other to achieve multi-level, multi-target,
multi-channel, uniform color and bright skin from the outside to the inside, lighten dullness,
help reducing wrinkle, moisturize skin. Therefore, SpecPlex® Gloss is recommended for toner,
serum, cream, lotion and other skin care products.
What is SpecPlex® Gloss
Easy to use

Product No.: 110052 Items Specification

Trade Name: SpecPlex® Gloss (NOI=80%)

Appearance Clear solution
INCI Name: Lactobionic Acid, Mandelic Acid, Tranexamic Acid, Carnosine, Nonapeptide-1,
Odor Characteristic
Niacinamide, Glycerin, 1,2-Hexanediol & Ethylhexylglycerin, water
CAS NO.: 96-82-2, 90-64-2, 1197-18-8, 305-84-0, 158563-45-2, 98-92-0, 56-81-5, 6920- pH 4.5-6.5

22-5 &70445-33-9, 7732-18-5 Refractive index (n25) 1.350-1.450

EC NO.: 202-538-3, 202-007-6, 214-818-2, 206-169-9, -, 202-713-4, 200-289-5, 230-
Heavy Metal (As) mg/kg ≤2
029-6 &408-080-2, 231-791-2
Heavy Metal (Cd) mg/kg ≤5
Application: Whitening/lightening, removing yellow, light spot, anti-aging (improve skin
elasticity), anti-glycosylation, moisturizing and etc. Heavy Metal (Hg) mg/kg ≤1

Dosage: 0.5-10.0% Heavy Metal (Pb) mg/kg ≤10

Storage: Store in a cool, ventilated place and keep container tightly sealed.
Aerobic plate count ≤ 100cfu/g
Shelf life: 2 years
Package: 25kg Yeast & mould ≤ 100cfu/g
What is SpecPlex® Gloss

Quality Control:
Heavy Metals (As, Cd, Hg, Pb) were not detected, under giving testing conditions.
What is SpecPlex® Gloss

The Features of SpecPlex® Gloss:

• Natural Original Complex with NOI=80%

• Safe and gentle to delicate skin, as well as to sensitive skin
• Soften skin surface and remove dead skin cells, smoothen sags and crests , normalize
keratinization
• Boost the production of collagen (↑>400% @ 0.1%) and Glycosaminoglycans (GAGs);
• Strengthen the structural and biochemical support of Skin’s extracellular matrix (ECM)
and skin barrier
• Plumping skin and increase skin elasticity
• Enhance your natural glow, cast Skin Highlighter and luster
• Relieve skin stress, show anti-allergic property, make skin multi-active
• Even skin tone, leave skin healthy/natural-looking
• Prevent and fade dull and yellowish tone, inhibit melanin deposit
• Nourish skin both externally and internally
Technical Supporting Data of SpecPlex® Gloss

The cytotoxicity of SpecPlex® Gloss (predict its oral toxicity)

SpecPlex® Gloss is super gentle and mild to your delicate skin, even at cellular level ! Cruelty Free

Conclusions:
• According to SN/T 2328-2009 and MTT method, the IC50 of SpecPlex ® Gloss is 2.6% on
the NIH/3T3 cell line.SpecPlex ® Gloss had no toxicity on NIH/3T3 cell line when the
concentration was not more than 1.56%.
• If converting above value into the acute oral toxicity LD50 of mice theoretically, then the
acute oral toxicity LD50 of SpecPlex ® Gloss was 4645mg/kg, so SpecPlex ® Gloss was
classified as grade 5 (non-toxic) according to GHS acute toxicity classification standard.

We Spec Chem promise that we don’t do any animal test.

Fig.1 Cell viability under different concentrations of SpecPlexTMGloss

Technical Supporting Data of SpecPlex® Gloss

The cytotoxicity of SpecPlex® Gloss （Melanocytes）

SpecPlex™ Gloss is super gentle and mild to your delicate skin, even at cellular level ! Cruelty Free

Fig.1 Cell viability under different concentrations of
Conclusions:
• According to SN/T 2328-2009 and MTT
method, the IC50 of SpecPlexTMGloss is
2.2% on the melanocyte cell.
SpecPlexTMGloss had no toxicity on
melanocyte cell when the concentration
was not more than 1.6%.
• SpecPlex™ Gloss will not disrupt the normal
SpecPlexTMGloss
function of melanocyte cell.

We Spec Chem promise that we don’t do any animal test.

Technical Supporting Data of SpecPlex® Gloss

Safety: Skin irritation & Corrosion on 3D Constituted Human Epidermis- (Testing sample: SpecPlex® Gloss)

Cosmetics and skin interactionsa Highly Similar Testing Process

Acute skin irritation is a local, reversible inflammatory The method employs a three dimensional (3D) human skin model Positive Negative SpecPlex®
response resulting from normal skin contact with irritating Group
with a functional epidermal stratum corneum structure, which is control control Gloss
drugs. The mechanism of skin irritation occurs because the evaluated by the percentage of the stimulating or corrosive Mean OD 0.117±0.01 0.849±0.01
test substance contacts the skin by expanding, infiltrating 0.794±0.028
threshold dose level defined by the test substance after the skin is 士SD 2 2
or destroying the epidermal barrier, and then acting on the exposed and the cell viability is decreased by measurement. The 100.00±1.4
stratum corneum cells to produce a toxic effect. irritant strength of the test substance.
Viability (%) 13.81±1.44 93.54±3.35
4
Conclusion: (according to OECD TG 439 chemicals in vitro skin irritation) reconstructed human epidermis test Result of skin irritation: super safe
method，under the testing conditions, the tissue viability of the sample “ SpecPlex™ Gloss“ is 93.54% (viability
>50% ) and it is considered as no skin irritation.
Technical Supporting Data of SpecPlex® Gloss

Safety: Skin irritation & Corrosion on 3D Constituted Human Epidermis- (Testing sample: SpecPlex® Gloss)

Testing Process Microscopic diagram

Fig 1. Negative Control Fig 2. SpecPlex® Gloss Fig 3. Positive Control

DPBS Buffer 5% SDS

Result of skin irritation

Group Positive Negative SpecPlex®
control control Gloss
Summary: 3D reconstructed human epidermis, Applying SpecPlex® Gloss didn’t
Mean OD 0.117 0.849 0.794 cause any skin tissue damage or morphologic changes, the skin model of Fig 2 still
士SD ±0.012 ±0.012 ±0.028 show integrated and clear morphology as Fig 1, compared with Fig 3.
Viability (%) 13.81 100.00 93.54
±1.44 ±1.44 ±3.35
Technical Supporting Data of SpecPlex® Gloss

The allergenicity (anti-allergic) of the SpecPlex® Gloss on mast cell

Negative Control Positive Control Gloss-20%

Gloss-10% Gloss-5% Gloss-2.5%

Gloss-1.25% Gloss-0.625% Gloss-0.3125%

Fig. 1 Effect of SpecPlex® Gloss on release rates of β-hexosaminidase at different
concentrations(***,p＜0.001 vs. negative control.The higher the release rate of β-
hexosaminidase, the stronger the allergenicity.)

According to the experimental results,SpecPlex® Gloss at the above different concentrations

did not significantly increase the release rates of allergy marker β-hexosaminidase in mast
cells, contrary to the positive control (Compound 48/80,allergen).
Therefore, SpecPlex® Gloss has no allergenicity under testing concentrations (up to 20%).
Fig.2 Cell morphology (A ,B and C-I were the negative control,positive control and SpecPlex® Gloss
Besides, SpecPlex® Gloss showed certain anti-allergic effect, because it inhibited the release
groups (20%,10%,5%,2.5%,1.25%,0.625%,0.3125%,respectively). There were no significant changes in
of allergy marker β-hexosaminidase in mast cells comparing with negative control. cell morphology of SpecPlex® Gloss groups compared with the negative control group.
Technical Supporting Data of SpecPlex® Gloss

• Components of the ECM are produced intracellularly by resident cells and

secreted into the ECM via exocytosis.
• Once secreted, they then aggregate with the existing matrix. The ECM is
composed of an interlocking mesh of fibrous proteins and glycosaminoglycans
(GAGs).
• Collagens are the most abundant protein in the ECM. In fact, collagen is the
most abundant protein in the human body and accounts for 90% of bone matrix
protein content.
• Collagens are present in the ECM as fibrillar proteins and give structural support
to resident cells.
• Elastins, in contrast to collagens, give elasticity to tissues, allowing them to
stretch when needed and then return to their original state. This is useful in skin,
and these tissues contain high amounts of elastins.
• Elastins are synthesized by fibroblasts and smooth muscle cells.
Technical Supporting Data of SpecPlex® Gloss

Promoting effect of SpecPlex® Gloss on collagen content in fibroblasts.

SpecPlex®Gloss promoted the collagen content in fibroblasts, and

the promotion rate reached 105% when the concentration was 0.1%,
Fig.1 Cell collagen content in different groups
and the promotion effect was concentration-dependent.
（***P＜0.001 vs. control cells）
Technical Supporting Data of SpecPlex® Gloss

Promoting ECM-related gene expression-SpecPlex™ Gloss

According to the results of PCR test, compared with blank control (BC) group,
SpecPlexTM Gloss can obviously promote the gene content of collagen I,
collagen VII and Laminin, i.e. the expression of ECM-related genes, to
enhance the ECM function.

Results of RT-PCR (Reverse transcription-Polymerase chain reaction) Test

Sample Mean SD P Value Gene

BC 1 0.05 / Collagen I

SpecPlex™ Gloss 1.29 0.09 0.009**

BC 1.01 0.19 / Collagen IV

SpecPlex™ Gloss 1.04 0.06 0.835

BC 1.00 0.03 / Collagen VII

SpecPlex™ Gloss 1.37 0.05 0.00**

BC 1.00 0.05 / Laminin

SpecPlex™ Gloss 1.24 0.04 0.003**

 Technical Supporting Data of SpecPlex® Gloss

Inhibition effect of SpecPlex® Gloss on tyrosinase activity in melanocytes.

A-Control B-Gloss 0.2% C-Gloss 0.1%

D-Gloss 0.05% E-Gloss 0.025% F-Gloss 0.0125%

Fig.5 Dopa staining of melanocytes (A and B-F were the control group and SpecPlex®Gloss group (0.2%, 0.1%, 0.05%,
0.025% and 0.0125%, respectively). The larger and darker of the dark brown area, the higher the activity of tyrosinase
in the cells .

Fig. 4 (up): Tyrosinase activity in different groups (the darker the color, the higher the tyrosinase
activity) ; (down) Inhibition effects of different concentrations of SpecPlexTM Gloss on the activity
of tyrosinase (*p＜0.05, **p＜0.01,***p＜0.001 vs.control)
Technical Supporting Data of SpecPlex® Gloss

Inhibition effect of SpecPlex® Gloss on Melanin production

SpecPlexTMGloss(%)

SpecPlex® Gloss(%)

Fig.7 Lysates of B16F10 melanocytes in different groups (the darker the color, the
higher the melanin production)

According to the results of cell tyrosinase activity test and cell dopa staining
experiment, SpecPlex® Gloss can inhibite the activity of tyrosinase in melanocytes.
The inhibition rate is 58.5% at 0.1% and IC50 is 633μg/mL（≈0.0633%）.
In addition, it also has a significant inhibitory effect on the production of melanin in
B16F10 melanocytes, the inhibitory rate reached 41.4% when the concentration was
Fig. 6 (Up): B16F10 melanocytes collected by centrifugation in different groups
0.4%.The inhibition effect is concentration dependent.
(the darker the color, the higher the melanin production) (Down): Inhibition
effects of different concentrations of SpecPlex™ Gloss on melanin production
(*p＜0.05, **p＜0.01,***p＜0.01 vs.control)
Technical Supporting Data of SpecPlex® Gloss

Clinically Brightening Effect of SpecPlex® Gloss

Test product：SpecPlex® Gloss (5.0%) Batch No： C20071503

Subjects： 37 females Age range: 25-55 years old
Performance Test: inclusion/exclusion criteria
Test Site：Face
Application Frequency：Twice a day after cleaning face in the morning and evening.
Test Period：28 days (2020.10.12 - 2020.11.09)
Test Parameters：
ITA ° (Defines the value of skin pigmentation. The higher the value, the lighter the skin tone.)
L* (Indicates the black and white brightness of the skin. The higher the melanin content, the smaller the value.)
a* (Represents the balance between red and green. The more rosy the skin, the higher the value.)
b*( Represents the balance between yellow and blue. The yellower the skin, the higher the value.)
Test condition：Temperature: 20℃- 25℃; Humidity: 40% - 60%;
Test instrument: C-CUBE (PIXIENCE); VisioFace 1000D
Design of Study: Aim to assess the brightening effect of the test cosmetic product after 28 days application, in the
female subject.
Technical Supporting Data of SpecPlex® Gloss

Clinically Brightening Effect of SpecPlex® Gloss “Zen-like” State in skin

Fig2 Change rate of the parameters at different time

Fig1 Changes in the value of the parameters at different time 16.00%
4.00

Change rate of the parameters

11.00%
the value of the parameters

3.00

2.00 6.00%

1.00
1.00%
0.00
7d 14d 28d
7d 14d 28d
-1.00 -4.00%

-2.00 -9.00%

-3.00
-14.00%
∆ITA° ∆L* ∆a* ∆b*
ITA° L* a* b*

The three coordinates of CIELAB represent the lightness of the color (L* = 0 yields black and L* = 100 indicates diffuse white; specular white may be higher), its position between red and green (a*,
where negative values indicate green and positive values indicate red) and its position between yellow and blue (b*,where negative values indicate blue and positive values indicate yellow).

According to theory of Individual Typology Angle & CIELAB Color Space and above results, 5% SpecPlex® Gloss can leaves skin harmoniously and
healthily pink-reflecting beauty with white, rather than limiting to a pure white skin color.
 Technical Supporting Data of SpecPlex® Gloss

Clinically Brightening Effect of SpecPlex® Gloss

Fig 3 the score of the test sample evaluted by the subjects Skin Photos of Typical Testing Subjects:

Irritation
5.00

4.00

Brightening effect 3.00 Moisturizing effect

2.00

Glossiness Smoothness

0 day 7 days 14 days 28 days

Technical Supporting Data of SpecPlex® Gloss

Clinically Brightening Effect of SpecPlex® Gloss

User Guide of SpecPlex ® Gloss

Product Name Supplier/ INCI Name w/w% Function

Cetearyl Olivate & Sorbitan Olivate 3.0 Emulsifier
Cetyl Palmitate & Sorbitan Palmitate and Sorbitan Olivate 1.5 Emulsifier
SpecSufc® M68 Spec Chem/ Cetearyl Glucoside &Cetearyl Alcohol 0.5 Emulsifier
SpecKare® GTCC Spec Chem/ Caprylic/capric Triglyceride 2.0 Emollient
Isopropyl Myristate 1.0 Emollient
Dicaprylyl Carbonate 3.0 Emollient
A
Butyrospermum Parkii (Shea Butter) 1.0 Emollient
SpecThem® C1618 Spec Chem/ Cetearyl Alcohol 2.0 Emollient
SpecThem® GMS Spec Chem/ Glyceryl Stearate 1.0 Emulsifier
Spec Chem/ Glyceryl Linoleate & Glyceryl Oleate & Glyceryl
SpecKare® 3GF 4.0 Humectant, Emollient
Linolenate
Dimethicone 2.0 Tactile Enhancers
Disodium EDTA 0.1 Chelating Agent
Clinical Test- Brightening Cream
Water To 100
Procedure:
Glycerin 5.0 Humectant
1. Mix Phase A and heat to 80℃,
Propylene Glycol 3.0 Humectant stirring until completely dissolved;
B SpecPlex® Gloss Spec Chem/ Lactobionic Acid, Mandelic Acid, Tranexamic Acid, 2. Mix Phase B components and stir
Carnosine, Nonapeptide-1, Niacinamide, Glycerin, 1,2-Hexanediol 5.0 Whitening Agent well;
&Ethylhexylglycerin, water 3. Add Phase A into B, homogenize for
SpecThem® XTG200 Spec Chem/ Xanthan gum 0.15 Stabilizer 3-5min;
Sodium Hydroxide（20%） q.s. pH controlling Agent 4. Disperse Phase C and cool the base
below 60℃, then add Phase C to above
Sodium Acrylate / Sodium Acryloyldimethyl Taurate Copolymer 0.6 Stabilizer
C sample;
Water 5
5. Cool the base below 45℃, add Phase
Spec Chem/ Poria cocos sclerotium extract, Portulaca Oleracea D, stirring until room temperature.
SpecPlex® PCalm Extract, Palmitoyl Tripeptide-8, Dipotassium Glycyrrhizate, 3.0 Relieve anti-allergic
D
Glycerin, Water

SpecKare® DPA Spec Chem/ Panthenol 0.5 Humectant

E ParbFree® CE85 Spec Chem/ Caprylyl Glycol, Ethylhexylglycerin 1.0 Preservative
User Guide of SpecPlex ® Gloss
Formulation Example 1: Glossy & Lifting Spray

Product Name Supplier/ INCI Name w/w% Function

Water To 100
Description：
Disodium EDTA 0.05 Chelating Agent This lifting and forming spray can erase dynamic wrinkles
instantaneously by using two Neurotransmitter inhibitory
Glycerin 3.0 Humectant
peptides- SpecPed® SKE & SpecPed® SC-AH8, and can also
A Butylene Glycol 2.0 Emollient speed up skin's metabolism to impart radiance and slow
Propylene Glycol 1.0 Emollient down melanin deposit to keep skin smooth bright and
charming by using SpecPlex™ Gloss.
SpecWhite® LBA Spec Chem/ 0.5 Lightening Agent
PVP 2.0 Sensory Agent

Spec Chem/ Lactobionic Acid, Mandelic Acid, Tranexamic Acid, Procedure:

SpecPlex® Gloss Carnosine, Nonapeptide-1, Niacinamide, Glycerin, 1,2-Hexanediol 3.0 Glossy Agent 1. Mix Phase A while stirring until uniform;
&Ethylhexylglycerin, water
2. Add Phase B and C into A while stirring until uniform;
Spec Chem/ Dipeptide diaminobutyroyl 5. Add Phase D to adjust pH to 5.5-6.5.
SpecPed® SKE (0.1%) Benzylamide diacetate, Glycerin, Caprylyl Glycol 1.0 Lifting & Firming Agent
&Ethylhexylglycerin, Water Properties:
Appearance: Clear yellowish liquid
SpecPed® SC-AH8 (0.05%) Spec Chem/ Acetyl Hexapeptide-8, Aqua, Caprylyl Glycol 5.0 Lifting & Firming Agent
B pH: 5.5±0.5 (1:10 aqueous solution)
SpecKare® HA (<10KDa) Spec Chem/ Sodium Hyaluronate 0.02 Humectant Stability:45 ℃ for a month; -18 ℃ for a month

SpecKare® DPA Spec Chem/ D-Panthenol 0.5 Humectant

Humectant
SpecKare® TRHL Spec Chem/ Trehalose 2.0
Emollient
Spec Chem/ Poria cocos sclerotium extract, Portulaca Oleracea
SpecPlex® PCalm Extract, Palmitoyl Tripeptide-8, Dipotassium Glycyrrhizate, 5.0 Calming Agent
Glycerin, Water
C ParbFree® PE91 Spec Chem/ 1,2-Hexanediol & Ethylhexylglycerin 1.0 Preservative
D Sodium Hydroxide q.s. pH Adjuster
User Guide of SpecPlex ® Gloss
Formulation Example 1: Glossy Essence
Product Name Supplier/ INCI Name w/w% Function Procedure:
Steareth-20 0.2 Stabilizer 1. Mix Phase B and heat to 85℃, stirring until
SpecSufc® M68 Spec Chem/ Cetearyl Glucoside and Cetearyl Alcohol 0.1 Emulsifier completely dissolved;
SpecThem® GMS Spec Chem/ Glyceryl Stearate 0.05 Emulsifier
2. Mix Phase C and D components and stir well at
85℃，add them into B
Dimethicone 1.0 Sensory Agent
A 3. Add Pre-dissolved Phase A at 85℃, homogenize
Squalane 1.0 Conditioning Agent for 5min;
SpecKare® VEA Spec Chem/ Tocopheryl Acetate 0.3 Antioxidant Agent 4. Cool the base below 60℃, then add Phase E to
Sodium Acrylate/Sodium above sample;
0.5 Thickener
Acryloyldimethyl Taurate Copolymer 5. Cool the base below 45℃, add Phase F, stirring
SpecThem® SCB21 Spec Chem/ Acrylates/C10-30 Alkyl Acrylate Crosspolymer 0.1 Thickener until room temperature.
B
Water 50.0
SpecThem® XTG200 Spec Chem/ Xanthan Gum 0.1 Stabilizer Properties:
Hydroxyethyl Cellulose 0.1 Stabilizer Appearance: White Essence
Glycerin 5.0 Humectant pH: 5.5±0.5 (1:10 aqueous solution)
C Butylene Glycol 3.0 Stability:45 ℃ for a month; -18 ℃ for a month
Emollient
Glycereth-26 2.0 Emollient
Solubilisant LRI Sensient/ PPG-26-Buteth-26 (and) PEG-40 Hydrogenated Castor Oil (and) Water 2.0 Solubilizer
Water To 100
Cyclodextrin 0.1 Sensory Agent
SpecKare® NMF50 Spec Chem/ Betaine 2.0 Humectant
D SpecKare® TRHL Spec Chem/ Trehalose 2.0 Humectant
Disodium EDTA 0.05 Chelating Agent
SpecKare® ALLA Spec Chem/ Allantoin 0.05 Conditioning Agent
E Arginine q.s. pH Adjuster
Spec Chem/ Poria cocos sclerotium extract, Portulaca Oleracea Extract, Palmitoyl
SpecPlex® PCalm 3.0 Calming Agent
Tripeptide-8, Dipotassium Glycyrrhizate, Glycerin, Water

F Spec Chem/ Lactobionic Acid, Mandelic Acid, Tranexamic Acid, Carnosine,

SpecPlex® Gloss 5.0 Glossy Agent
Nonapeptide-1, Niacinamide, Glycerin, 1,2-Hexanediol &Ethylhexylglycerin, water
SpecKare® DPA Spec Chem/ D-Panthenol 0.5 Emollient
PrzvFree® CE85 Spec Chem/ Caprylyl Glycol, Ethylhexylglycerin 0.8 Preservative
User Guide of SpecPlex ® Gloss

Stability Test : (Initial @ RT pH=5.56)

• Usage: Water Soluble, easy to use, cold process capable, Add below 45℃

• Recommended dosage: Daily use:0.5-10.0%

• Intensive use: 10.0-20.0%

• Recommended pH: 5.5-7.0, 6.5 prefer

Stability Test : (after 3 month @ RT)

• Stability: Stable at various temperature with clear appearance

• Recommended Application: Anti-stress, Anti-pollution, Skin Lightening, Skin

smoothing, Anti-premature aging, Anti-aging, etc. Both can be used in rinse-off and

leave-on products.
3-month Speed-up Stability Test @ various temp
Application Center ·