The document contains summaries of multiple studies on changes to anterior segment parameters after glaucoma surgeries and implants. The studies found:
1) PreserFlo MicroShunt implantation results in minimal and temporary changes to the cornea and anterior chamber in the early postoperative period.
2) PreserFlo MicroShunt induces mild and transient changes to corneal astigmatism, axial length, and anterior chamber depth in the early postoperative period.
3) A shorter distance between the PreserFlo MicroShunt tube and the cornea causes more endothelial cell loss immediately after surgery, but the loss reduces over time.
The document contains summaries of multiple studies on changes to anterior segment parameters after glaucoma surgeries and implants. The studies found:
1) PreserFlo MicroShunt implantation results in minimal and temporary changes to the cornea and anterior chamber in the early postoperative period.
2) PreserFlo MicroShunt induces mild and transient changes to corneal astigmatism, axial length, and anterior chamber depth in the early postoperative period.
3) A shorter distance between the PreserFlo MicroShunt tube and the cornea causes more endothelial cell loss immediately after surgery, but the loss reduces over time.
The document contains summaries of multiple studies on changes to anterior segment parameters after glaucoma surgeries and implants. The studies found:
1) PreserFlo MicroShunt implantation results in minimal and temporary changes to the cornea and anterior chamber in the early postoperative period.
2) PreserFlo MicroShunt induces mild and transient changes to corneal astigmatism, axial length, and anterior chamber depth in the early postoperative period.
3) A shorter distance between the PreserFlo MicroShunt tube and the cornea causes more endothelial cell loss immediately after surgery, but the loss reduces over time.
The document contains summaries of multiple studies on changes to anterior segment parameters after glaucoma surgeries and implants. The studies found:
1) PreserFlo MicroShunt implantation results in minimal and temporary changes to the cornea and anterior chamber in the early postoperative period.
2) PreserFlo MicroShunt induces mild and transient changes to corneal astigmatism, axial length, and anterior chamber depth in the early postoperative period.
3) A shorter distance between the PreserFlo MicroShunt tube and the cornea causes more endothelial cell loss immediately after surgery, but the loss reduces over time.
Gambini G. Prospective Apart from significant PreserFlo implantation
et al. 2023 decrease in intraocular reduces the alterations to design pressure from from 20.9 ± 4.0 the anterior chamber as to 8.0 ± 2.8 mmHg (p < 0.0001) compared to conventional Early post- and to 10.8 ± 3.7 mmHg (p = filtering surgery, producing operative 0.0001) at day-1 and week-1. minimal & temporary anterior segment Anterior chamber parameters changes in biometrics of parameters such as TCA (total corneal the cornea in the modificatio ns induced astigmatism) changed postoperative period as by significantly from baseline (1.5 well as negligible PreserFlo MicroShunt ± 1.2 D) to both day 1 follow alterations to the ACD and in primary up (2.7 ± 1.9 D, p = 0.0003) ACV, demonstrating its open-angle glaucoma and week 1 follow up (2.2 ± minimal invasiveness and 1.6 D, p = 0.02). K1 showed safety. transient flattening at day 1 while K2 did not have any significant changes in the early postoperative period.There is rise in CCT value significantly at day 1(547 ± 49 vs. 529 ± 32 µm at baseline, p = 0.04), but then returned toward pre- operative values at week 1 (537 ± 39 µm, p = 0.57).However, no significant changes noted in both ACD and ACV values in eyes during the early postoperative period. M.I Barbera Prospective Two groups were analysed , Preserflo MicroShunt et al 2021 design one group where device was implant for glaucoma implanted as a stand-alone surgery induces mild and procedure & the other group transient changes in Changes to combined with cataract corneal astigmatism , axial corneal surgery. The anterior surface length & anterior chamber topography astigmatism, posterior surface depth in the early and astigmatism & total corneal postoperative period. biometrics astigmatism(TCA) increased in after each group 0.4±0.3/0.2±1.0 D, PreserFlo 0.08±0.1/0.03±0.1 D and MicroShunt 0.4±0.3/0.2±0.9 D surgery for respectively, at 3 months. In glaucoma the first week , there was increase (P=0.01) in anterior & posterior cornea elevation(ACE max, ACE min, PCE max) with no significant changes at 3 months. The AL decreased in both groups. There was a significant correlation between the IOP and the maximum elevation of the posterior surface of the cornea at the preoperative examination (r=0.93, P=0.02). Prospective The decrease of central A shorter tube-endothelial design endothelial cell density(ECD) distance causes more M.I Barbera decreases significantly at 1 corneal endothelial cell et al 2022 year(7.4%, p=0.04) where a density loss from the significant correlation of tube- immediate postoperative endothelial(TE) distance were period. However , the loss noted. Regarding TE distance of ECD reduces & has lower groups, in the < 200 μm group rates with time. Corneal there was 18% ECD reduction Endothelial vs. 1% in the > 500 μm group Cell Loss (p = 0.08). Endothelial cell loss After was related to TE distance PreserFlo (mean 482.9 ± 238 μm), with a MicroShunt higher rate at 1 month in Implantatio comparison to 12 months for n in the the same tube position in the Anterior anterior chamber (-174.8 ± Chamber: 65.2 cells/mm2 at 1 month vs. Anterior 30.2 ± 11.3 cells/mm2 at 12 Segment months, p < 0.01). From OCT Tube month 6, tubes located > 600 Location as μm from the endothelium a Risk showed EC loss close to zero. Factor A Alvani et Post trabeculectomy, a In conclusion, changes in al 2016 significant and persistent AL ACD insignificant and reduction, with a range of 0.1- transient. However, AL 0.19 and 0.1-0.9 mm changes and keratometry Ocular measured with contact and are of sufficient magnitude Biometric non-contact methods, and can affect the Changes respectively, was observed. refractive prediction of After With respect to topographic combined cataract surgery Trabeculect changes, 0.38-1.4 diopters (D) and trabeculectomy. omy with-the-rule (WTR) astigmatism was induced postoperatively. Immediate ACD reduction postoperatively, approximates its preoperative levels after 2 weeks. ACD reduction was insignificant in majority of cases.
Simsek M et Prospective In comparison with Our results showed that the
al 2018 preoperative values, ACA, changes in the anterior design ACD, and ACV values segment parameters decreased but CCT value observed in the early Stabilization increased in the 1st postoperative period after time of postoperative week (P<0.001). trabeculectomy returned to anterior In the 1st postoperative month, their baseline values after segment ACA, ACD, and ACV values approximately 1 month parameters significantly increased but CCT after the surgery and after value significantly decreased remained stable thereafter. trabeculect (P=0.002 for ACV; P<0.001 for omy ACA, ACD, and CCT). However, surgery no significant differences were observed between the baseline and 1st postoperative-month values (P>0.05 for all the parameters).