Study Design Table Anterior Segment

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Article Study Results Conclusion

design

Gambini G. Prospective Apart from significant PreserFlo implantation


et al. 2023 decrease in intraocular reduces the alterations to
design
pressure from from 20.9 ± 4.0 the anterior chamber as
to 8.0 ± 2.8 mmHg (p < 0.0001) compared to conventional
Early post- and to 10.8 ± 3.7 mmHg (p = filtering surgery, producing
operative
0.0001) at day-1 and week-1. minimal & temporary
anterior
segment Anterior chamber parameters changes in biometrics of
parameters
such as TCA (total corneal the cornea in the
modificatio
ns induced astigmatism) changed postoperative period as
by
significantly from baseline (1.5 well as negligible
PreserFlo
MicroShunt ± 1.2 D) to both day 1 follow alterations to the ACD and
in primary
up (2.7 ± 1.9 D, p = 0.0003) ACV, demonstrating its
open-angle
glaucoma and week 1 follow up (2.2 ± minimal invasiveness and
1.6 D, p = 0.02). K1 showed safety.
transient flattening at day 1
while K2 did not have any
significant changes in the early
postoperative period.There is
rise in CCT value significantly
at day 1(547 ± 49 vs. 529 ± 32
µm at baseline, p = 0.04), but
then returned toward pre-
operative values at week 1
(537 ± 39 µm, p =
0.57).However, no significant
changes noted in both ACD
and ACV values in eyes during
the early postoperative period.
M.I Barbera Prospective Two groups were analysed , Preserflo MicroShunt
et al 2021 design one group where device was implant for glaucoma
implanted as a stand-alone surgery induces mild and
procedure & the other group transient changes in
Changes to combined with cataract corneal astigmatism , axial
corneal surgery. The anterior surface length & anterior chamber
topography astigmatism, posterior surface depth in the early
and astigmatism & total corneal postoperative period.
biometrics astigmatism(TCA) increased in
after each group 0.4±0.3/0.2±1.0 D,
PreserFlo 0.08±0.1/0.03±0.1 D and
MicroShunt 0.4±0.3/0.2±0.9 D
surgery for respectively, at 3 months. In
glaucoma the first week , there was
increase (P=0.01) in anterior &
posterior cornea
elevation(ACE max, ACE min,
PCE max) with no significant
changes at 3 months. The AL
decreased in both groups.
There was a significant
correlation between the IOP
and the maximum elevation of
the posterior surface of the
cornea at the preoperative
examination (r=0.93, P=0.02).
Prospective The decrease of central A shorter tube-endothelial
design endothelial cell density(ECD) distance causes more
M.I Barbera
decreases significantly at 1 corneal endothelial cell
et al 2022
year(7.4%, p=0.04) where a density loss from the
significant correlation of tube- immediate postoperative
endothelial(TE) distance were period. However , the loss
noted. Regarding TE distance of ECD reduces & has lower
groups, in the < 200 μm group rates with time.
Corneal there was 18% ECD reduction
Endothelial vs. 1% in the > 500 μm group
Cell Loss (p = 0.08). Endothelial cell loss
After was related to TE distance
PreserFlo (mean 482.9 ± 238 μm), with a
MicroShunt higher rate at 1 month in
Implantatio comparison to 12 months for
n in the the same tube position in the
Anterior anterior chamber (-174.8 ±
Chamber: 65.2 cells/mm2 at 1 month vs.
Anterior 30.2 ± 11.3 cells/mm2 at 12
Segment months, p < 0.01). From
OCT Tube month 6, tubes located > 600
Location as μm from the endothelium
a Risk showed EC loss close to zero.
Factor
A Alvani et Post trabeculectomy, a In conclusion, changes in
al 2016 significant and persistent AL ACD insignificant and
reduction, with a range of 0.1- transient. However, AL
0.19 and 0.1-0.9 mm changes and keratometry
Ocular measured with contact and are of sufficient magnitude
Biometric non-contact methods, and can affect the
Changes respectively, was observed. refractive prediction of
After With respect to topographic combined cataract surgery
Trabeculect changes, 0.38-1.4 diopters (D) and trabeculectomy.
omy with-the-rule (WTR)
astigmatism was induced
postoperatively. Immediate
ACD reduction
postoperatively, approximates
its preoperative levels after 2
weeks. ACD reduction was
insignificant in majority of
cases.

Simsek M et Prospective In comparison with Our results showed that the


al 2018 preoperative values, ACA, changes in the anterior
design
ACD, and ACV values segment parameters
decreased but CCT value observed in the early
Stabilization increased in the 1st postoperative period after
time of postoperative week (P<0.001). trabeculectomy returned to
anterior In the 1st postoperative month, their baseline values after
segment ACA, ACD, and ACV values approximately 1 month
parameters significantly increased but CCT after the surgery and
after value significantly decreased remained stable thereafter.
trabeculect (P=0.002 for ACV; P<0.001 for
omy ACA, ACD, and CCT). However,
surgery no significant differences were
observed between the
baseline and 1st
postoperative-month values
(P>0.05 for all the
parameters).

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