Professional Documents
Culture Documents
ME Sci 9 Q1 0104 TG
ME Sci 9 Q1 0104 TG
LESSON 1.4
Transport of Nutrients, Gases, and Other Molecules
Table of Contents
Learning Competency 1
Learning Objectives 1
Essential Questions 1
Prerequisite Topics 2
Lesson Proper 2
A. Introduction to the Lesson 2
B. Discussion 10
C. Practice & Feedback 17
Assess Performance 17
Synthesis 21
Bibliography 21
Grade 9 • Unit 1: Respiratory and Circulatory Systems
Learning Competency
At the end of this lesson, the given DepEd learning competency should be met
by the students.
● Explain how the respiratory and circulatory systems work together to
transport nutrients, gases, and other molecules to and from the different
parts of the body (S9LT-la-b-26).
Learning Objectives
In this lesson, you should be able to do the following:
● Explain the mechanism of how the respiratory and circulatory systems
work together in transporting nutrients, gases, and other materials within
an organism.
● Determine the mechanisms of material transport through blood.
Essential Questions
At the end of this lesson, the student should be able to answer the following questions.
● How does hemoglobin help the red blood cell carry out its function?
1
Grade 9 • Unit 1: Respiratory and Circulatory Systems
● How do the respiratory and circulatory systems work together to provide vital
materials in the body?
Prerequisite Topics
The students should know the following prerequisite topics before proceeding with the
lesson.
● Parts and functions of the respiratory system
● Parts and functions of the circulatory system
● Diffusion and osmosis
Lesson Proper
1. Recall the concept of diffusion and how it induces the gas exchange to occur. Where
is the site of the gas exchange? What is the mechanism for the exchange of gases
between the alveoli and the blood in the capillaries?
a. The gas exchange specifically happens in the alveoli within the lungs.
b. The mechanism for the exchange of gases between the alveoli and the blood
in the capillaries is diffusion. Diffusion is the movement of gases from a
higher concentration to a lower concentration.
i. Diffusion in the lungs happens when there is a difference in the
concentration of oxygen or carbon dioxide between the air inside the
alveoli and the blood within capillaries.
2
Grade 9 • Unit 1: Respiratory and Circulatory Systems
2. Identify the role of the circulatory system and the parts that work together to
perform its function. What is the circulatory system’s function? What are the
components of the circulatory system?
a. The major system responsible for the distribution and pumping of blood is
the circulatory system.
b. The components that serve as the transportation in the human body are
composed of the blood, the blood vessels, and the heart.
3. Recall the flow of blood inside the body. What are the two circulation loops? How does
the blood flow inside the body?
a. There are two major circulation loops namely the systemic and the
pulmonary circulation loops.
i. The systemic circulation loop is where oxygenated blood
(oxygen-rich, carbon dioxide-poor) is distributed into the body’s
systems (heart to the other organs).
ii. Coronary circulation is a part of the systemic circulation loop that is
the circulation of blood in the blood vessels of the heart muscle.
iii. The pulmonary circulation loop is when the deoxygenated blood
(oxygen-poor, carbon dioxide-rich) from the systemic circulation
returns to the heart. It enables the refilling of the oxygen in the blood
and the release of carbon dioxide.
b. The flow of blood in the systemic circulation is as follows:
3
Grade 9 • Unit 1: Respiratory and Circulatory Systems
i. Blood enters the heart via the two large veins called the inferior and
superior vena cava.
ii. The blood leaves the heart through the pulmonary arteries that lead
to the lungs.
iii. The oxygenated blood returns to the heart via the pulmonary veins.
iv. To prevent backflow of the blood, the heart has two valves namely the
tricuspid valve and the mitral valve. These two valves alternately
open and close during the pumping of the blood.
c. Use Option A to recall body reactions and relate them to the processes in
the circulatory system.
Procedure:
1. Identify which instances you can relate to, then recall your experiences.
2. Share your experiences with your seatmate.
4
Grade 9 • Unit 1: Respiratory and Circulatory Systems
Guide Questions:
1. What exactly did you feel based on your experiences?
Students’ answers may vary.
5
Grade 9 • Unit 1: Respiratory and Circulatory Systems
4. Recall the function of the heart. How does the heart act as a pump?
a. The heart is composed of strong cardiac muscle tissues that continuously
contract and relax.
b. The heart plays a vital role in pumping blood throughout the body.
i. It has four major chambers: two atria and two ventricles.
ii. These four chambers are highly coordinated in pumping blood that
must deliver oxygen to the tissues and take carbon dioxide for
disposal.
iii. The valves in the heart prevent the backflow of blood.
c. Use Option B to reiterate the function of the heart in the body.
Materials:
● computer and LCD projector (option 1)
● printed copy of the two figures below (option 2)
Procedure:
1. Distribute copies of the two figures below or flash them on screen using
the LCD projector.
6
Grade 9 • Unit 1: Respiratory and Circulatory Systems
2. Ask the students to study the two pictures below. With a seatmate, ask
them to discuss what the illustrations are depicting.
Guide Questions:
1. What are the illustrations depicting?
Answer: The first illustration is showing the struggle of a person in choosing
what to follow, brain or heart. The second illustration shows a person
7
Grade 9 • Unit 1: Respiratory and Circulatory Systems
trying to balance the heart and brain or it tells us that in life, the heart
should weigh more than the brain.
2. Using your scientific knowledge, what is wrong with the illustration?
Answer: There should be no battle on what to follow since the only function
of the heart is to pump blood. The heart does not have any control over
emotions or decisions.
5. Recall the function of blood and describe the types of blood cells and platelets. What
is the role of blood cells and platelets in the body?
a. The blood is the most abundant body fluid in humans. It is responsible for
transporting materials and for immune defense.
b. Red blood cells take oxygen in the lungs and deliver it to the tissues. It also
transports carbon dioxide and releases it into the lungs.
c. White blood cells (WBC) are immune cells involved in protecting the body
against infectious agents and foreign bodies.
d. Platelets help in the clotting of blood during an injury.
e. Use Option C to introduce red blood cells, white blood cells, and platelets.
Material:
● gadget with an internet connection
Teacher’s Preparation:
● Prepare a worksheet with the lyrics stated below.
8
Grade 9 • Unit 1: Respiratory and Circulatory Systems
Procedure:
1. Click the link to watch and listen to the song in the following video. Then,
fill in the missing lyrics shown below.
2. Ask student volunteers to list the missing words on the board. Let the
students come up with one concept where all of the missing words are
related to.
Guide Questions:
1. What are the missing lyrics?
9
Grade 9 • Unit 1: Respiratory and Circulatory Systems
Answer: The missing lyrics are (1) heart, (2) heart, (3) vein, (4) bleeding.
2. What body system are the missing words related to?
Answer: Circulatory system
3. What is the function of the missing words?
Answer: The heart pumps blood throughout the body, the vein is a kind of
blood vessel where deoxygenated blood flows, and bleeding refers to the
blood which transports nutrients and respiratory gases.
Teacher’s Notes
The activity is used to recall the components of the circulatory system.
B. Discussion
Using the jumping boards presented in the Introduction, start the discussion of the lesson
by using the flow below.
1. Discuss the two means of transporting materials through the blood. What are the
mechanisms of material transport through blood?
a. There are two means of transporting materials through the blood. It can be
through the plasma or by binding to the red blood cells.
b. The first means is the transport of materials via blood plasma. Blood
transports nutrients and hormones by dissolving these materials in the liquid
component of the blood, which is the plasma. The absorbed nutrients in the
digestive system are directly dissolved in the plasma for immediate
transport. Hormones are secreted by the hormonal organs into the blood
which mixes directly into the plasma. Waste materials like excess salts and
urea are also transported by the blood through incorporation into plasma.
c. The second means is the transport of gases via red blood cells. Gases like
oxygen and carbon dioxide can be transported in the blood plasma.
However, only a small portion of what is needed by the body cells can be
10
Grade 9 • Unit 1: Respiratory and Circulatory Systems
transported in this manner. For this, oxygen and carbon dioxide transport
heavily rely on red blood cells.
d. Use Option A to help the students have a background on the characteristics
of red blood cells.
e. Use Option B to help students realize how important blood is by organizing a
blood drive.
Material:
● gadget with an internet connection
Procedure:
1. Click the link to watch a short video about red blood cells. Then, answer
the guide questions that follow.
2. Divide the class into three groups. Each group should act on the scene
assigned to them. Remind the students that they should make their own
script based on how they understood the scene from the video in the link
above. Then, they need to relate the scene to the actual scenario in the
human body,
a. Group 1 - graduation day in the bone marrow
11
Grade 9 • Unit 1: Respiratory and Circulatory Systems
Guide Questions:
1. Where are the premature red blood cells located?
Answer: In the red bone marrow.
2. What does the graduation day of little RBCs represent?
Answer: The graduation day represents enucleation where the core of the
erythroblasts is removed and becomes a mature red blood cell.
3. How does enucleation help the mature red blood cells to carry out their
function?
Answer: The enucleation will give red blood cells more area for carrying
respiratory gases.
4. What are hematopoietic stem cells?
Answer: Cells that produce blood cells such as white blood cells, red blood
cells, and platelets.
5. What is the role of the macrophages?
Answer: It plays a role in the differentiation and maturation of
erythroblasts.
6. What does the maze that the children played represent?
Answer: It represents the path where blood should circulate.
Teacher’s Notes
This activity can help students visualize the role of red blood cells.
12
Grade 9 • Unit 1: Respiratory and Circulatory Systems
Teacher’s Preparation:
● Talk to the local community blood center representative and the school’s
principal to set up a date for the blood drive.
● Set up meetings with the student members of the blood drive committee.
● Ensure all student chairpersons will fulfill their responsibilities.
Procedure:
1. Assign the following roles to responsible students.
a. Blood drive coordinator
b. Donor recruitment chairperson
c. Promotion chairperson
d. Site preparation chairperson
2. Divide the remaining students of the class into four groups. They will be
distributed to the four chairpersons and help with the responsibilities.
3. The role of the chairpersons and the members of the team are as follows:
a. Blood drive coordinator - prepare announcement flyers or posters
about the blood drive a week before the signup and prior to the
actual day of the blood drive as a reminder. The coordinator of the
team needs to ensure that the responsibilities of the three teams
are fulfilled.
b. Donor recruitment chairperson - recruit people who want to
donate. Prepare a signup list for the interested people and let them
provide their contact numbers so you could contact them on the
day or a day prior to the blood drive.
c. Promotion chairperson - ask permission from the principal before
putting the posters or giving fliers to students about the blood
drive. Coordinate with the school principal and local community
blood center if a seminar is possible to increase awareness on the
need for blood donation. You can also coordinate with the parent’s
association so you can also involve parents who want to donate
blood.
13
Grade 9 • Unit 1: Respiratory and Circulatory Systems
d. Site preparation chairperson - make sure that the site where the
blood drive will be held is ready. Ensure that the place has enough
ventilation (electric fans or aircon). Do not forget to provide a table
and several chairs.
Guide Questions:
1. What personal learnings did you get from the blood drive activity?
Students’ answers may vary.
2. How important is the role of blood in humans?
Answer: It is responsible for the circulation of important nutrients and
respiratory gases in order for cells to function properly.
Teacher’s Notes
This activity can help students realize the importance of blood in one's body
2. Describe the features and role of hemoglobin. What does hemoglobin look like? What
is the role of hemoglobin?
a. Hemoglobin is the iron-containing protein present in the red blood cells. It
carries oxygen and carbon dioxide to the different parts of the body.
b. A mature hemoglobin consists of four subunits, each containing an iron
atom bound to a heme group. The iron atom is important as it is the one
that binds to the gas molecules.
c. When hemoglobin is loaded with oxygen, it can be referred to as
oxyhemoglobin. It is characterized by a bright red color. In contrast,
deoxyhemoglobin is the form of hemoglobin without oxygen that is purple to
bluish.
d. Use Option C to create a hemoglobin model.
14
Grade 9 • Unit 1: Respiratory and Circulatory Systems
Materials:
● needle
● two orange pipe cleaners
● two red pipe cleaners
● four red buttons
● thread
Procedure:
1. Ask the students to perform the following steps in order to
make a hemoglobin model.
a. Fold each pipe cleaner similar to the figure shown below.
15
Grade 9 • Unit 1: Respiratory and Circulatory Systems
Guide Questions:
1. What do the pipe cleaners represent?
Answer: It represents the four globin chains of hemoglobin.
2. Why are there two colors of pipe cleaner to make a model of hemoglobin?
What does it represent?
Answer: The two same colors of pipe cleaners represent an alpha chain
while the other two same colors represent the beta chain.
3. What does the red button represent? What is it for?
Answer: The red button represents iron. The iron atom is important as it is
the one that binds to the gas molecules.
4. Based on your model, how would you describe the structure of
hemoglobin?
Answer: The hemoglobin is an iron-containing protein present in the red
blood cells which consist of four globin chains.
Teacher’s Notes
This activity can help students remember the role of the hemoglobin.
16
Grade 9 • Unit 1: Respiratory and Circulatory Systems
1. Ask the students to individually answer the following in their notebooks. The
teacher will ask a volunteer to recite his/her answer and check if the answer is
correct.
A. Identify what is being described in each item.
i. The liquid component of blood. Answer: plasma
ii. These are secreted by the hormonal organs into the blood which
mixes directly to the plasma. Answer: hormones
iii. These are round and flat cells with an indention in the center like
doughnuts without a hole. Answer: Red blood cells
iv. This atom is the one that binds to the gas molecules. Answer: Iron
atom
v. It refers to hemoglobin loaded with oxygen. Answer: oxyhemoglobin
vi. It is the form of hemoglobin without oxygen that is purple to bluish.
Answer: deoxyhemoglobin
Performance Assessment
Use the following activities to assess understanding.
1. S Y H O Y E R T R C E T
2. O N H M O L B E G I
3. A L A P M S
17
Grade 9 • Unit 1: Respiratory and Circulatory Systems
4. N R O I
5. Y N X G E O
Answer Key:
It transports nutrients,
3. A L A P M S Plasma hormones, and proteins to the
parts of the body that needs it.
Use the Check Your Understanding section in the study guide. Students
II. may answer it in their notebooks, and they will be checked and graded
afterward. Choose only selected items if not possible due to time.
A. Identify how each given material is transported by the blood. Put letter A if it
is transported by the plasma and letter B if the transport is through the
hemoglobin of the red blood cells.
1. urea Answer: A
2. carbon dioxide Answer: B
18
Grade 9 • Unit 1: Respiratory and Circulatory Systems
3. progesterone Answer: A
4. glucose Answer: A
5. amino acids Answer: A
6. water Answer: A
7. salts Answer: A
8. oxygen Answer: B
9. testosterone Answer: A
10. creatine Answer: A
B. Explain the reason for each of the following occurrences then identify its
importance in the body.
Answer Key:
Occurrence Explanation Importance
19
Grade 9 • Unit 1: Respiratory and Circulatory Systems
RBC during
It will have the space to
RBCs transport maturity has an
carry and transport
materials at maturity indention at the
materials.
center.
IV. Additional worksheets during class when time permits or after class.
20
Grade 9 • Unit 1: Respiratory and Circulatory Systems
Synthesis
Use the following strategies to end the lesson.
2. To further deepen understanding, you may also ask the following questions.
a. Why is the red blood cell enucleated?
Answer: The enucleation of red blood cells is an adaptation for its role. The
biconcave shape aids diffusion and allows the cell to have more hemoglobin
hence, more oxygen molecules.
b. Why is the blood-red in color?
Answer: The blood is red in color because of hemes, a subunit making up
each hemoglobin protein.
3. Read in advance the next lesson which discusses in detail the respiratory and
cardiovascular health.
Bibliography
Johnson, George B. and Peter H. Raven. 2001. Biology: Principles & Explorations. Austin: Holt,
Rinehart and Winston.
21
Grade 9 • Unit 1: Respiratory and Circulatory Systems
McLaughlin, Daniel P., Jonathan A. Stamford, and David A. White. 2007. Human Physiology.
London: Routledge.
Reece, Jane B. and Neil A. Campbell. 2011. Campbell Biology. Boston: Benjamin
Cummings/Pearson.
Riddel, Jennifer. 2012. Your Body's Systems. Pdf. Open School BC.
Weller, Alan. 2011. Human Anatomy. New York: Dover Pictura Electronic.
22
Grade 9 • Unit 1: Respiratory and Circulatory Systems
True or False. Write true if the statement is correct and false if incorrect (10 points).
23
Grade 9 • Unit 1: Respiratory and Circulatory Systems
A. Short-Response Answers. Use the given figure to answer the questions that follow. (6
points)
24
Grade 9 • Unit 1: Respiratory and Circulatory Systems
6. How many oxygen molecules are carried on 100 molecules of hemoglobin that are
completely saturated? Answer: 400 molecules of oxygen.
Number of hemoglobin molecules per red blood cell 250 million molecules
25
Grade 9 • Unit 1: Respiratory and Circulatory Systems
Short-Response Essay. Provide concise and accurate answers to the following questions (5
points for each item).
1. Beans, tofu, baked potatoes, and cashews are examples of foods that are rich in
iron. Do you think it is important to get enough iron in your diet? Why or why not?
Answers: Iron has several advantages such as healthy pregnancy, increased energy,
and better athletic performance. However, too much iron could elevate the risk for
liver cancer and diabetes.
2. Doping is where people are injected with erythropoietin. The result will be an
increase in the number of red blood cells in the body. This is done to improve the
ability to obtain oxygen to the cells of the muscle. Do you think blood doping should
be allowed in athletics? Why or why not?
Answers: If doping will be allowed in sports, the competition will no longer depend
on the humane natural strength and endurance but science and medicine instead
since the more medicine the athlete uses, the more advantage the athlete has.
26