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Required Practical: CP16 Title of experiment: Synthesise aspirin from 2-hydroxybenzoic acid

Outline of procedure:

Hazardous substances/procedure Nature of the hazards Control measures Information source


(precautions)
(Full URL, date accessed or page reference)

Ethanoic anhydride Causes severe skin burns, Wear splash proof goggles https://science.cleapss.org.uk/Resource/SSS069-
irritant to the skin, may cause Ethanoic-anhydride.pdf
Dispense in a fume cupboard.
respiratory irritation.
Avoid inhaling the vapour.

Take care to avoid skin contact

2-hydroxybenzoic Irritant, corrosive, health Use the smallest amount https://science.cleapss.org.uk/resource/sss026-


hazard. Causes serious eye possible. salicylic-acid-asprin-salol-and-oil-of-
damage; harmful if swallowed. wintergreen.pdf
Wear eye protection.

Ensure good ventilation.

Concentrated sulfuric acid Corrosive. Danger. It causes Use lowest concentration https://science.cleapss.org.uk/resource/sss022-
severe skin burns and eye possible sulfuric-vi-acid.pdf
damage. It reacts violently,
Use the smallest volume
becoming very hot, when
possible
mixed with water.
Wear eye protection

Disposals: Carried out by: Julia AL Kaouri

Checked by:

Date:

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