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Anthroschools Human Evolution Resource Pack - Biology A-Level
Anthroschools Human Evolution Resource Pack - Biology A-Level
UCL AnthroSchools
Table of Contents
Teacher’s Guide....................................................................................................................3
How to Use this Resource Pack................................................................................................3
Aims of the resource pack...........................................................................................................................3
Syllabus Points.............................................................................................................................6
1.1 Human adaptations and selection pressures in hominid evolution................7
Learning Outcomes......................................................................................................................7
Adaptations in hominids..............................................................................................................................7
Theories of bipedalism.................................................................................................................................8
Suggested Timings.....................................................................................................................................18
Syllabus Points...........................................................................................................................18
2.1 Processes of evolution...............................................................................................19
Learning Outcomes....................................................................................................................19
Speciation....................................................................................................................................................19
What does evolution look like?.................................................................................................................19
Extra Resources..................................................................................................................30
Glossary................................................................................................................................31
3
Teacher’s Guide
How to Use this Resource Pack
We hope that the materials provided here will challenge students to apply their
knowledge of human evolution and reinforce their learning in A-level Biology.
Contained within this resource pack are a series of worksheets that address core
topics on evolution in A-level Biology. In this how-to-use guide, we will provide you
with some brief guidance about how to get the most out of the worksheets to apply
anthropological knowledge to biology material at A-level.
This covers the following points in the AQA A-Level Biology Syllabus
While sections build on each other, if you would like to select a particular,
individual section to address one specific topic (e.g. lactose intolerance), you can.
Students can either fill out the worksheet continuously over a series of lessons or
they can simply focus on a particular topic and return to the worksheet at another
time.
The pack has been designed to give you the most flexibility and challenge your
students to think across topics while continuously supporting their learning.
Some sections ask students to read an article, watch a video or analyse a graph and
then respond to questions using both the source material and the knowledge they
have gained from classroom or textbook learning. Any external materials (videos,
websites, articles) in the worksheet are from exclusively open access resources, all
available through hyperlinks provided.
The worksheets can be completed digitally or printed. Estimated timings for each
section are provided, though you are of course welcome to adjust the timings.
5
We will be adjusting this resource and adding some more, so make sure to check
back regularly at https://www.ucl.ac.uk/anthropology/anthroschools/teaching-
resources.
6
Sections
1.1. Human adaptations and selection pressures in hominid evolution
1.2. Recognising selection from fossil evidence and data
1.3. Natural selection in lactose intolerance and adaptive phenotypes
1.4. Phenotypes and environment - Sickle cell case study
Suggested Timings
1.1. 20-30mins
1.2. 20-30mins
1.3. 25-35mins
1.4. 25-30mins
Syllabus Points
3.4 Genetic information, variation and relationships between organisms
3.4.4 Genetic diversity and adaptation
Genetic diversity as the number of different alleles of genes in a population and its
importance for natural selection.
The principles of natural selection and its mechanism
Directional and stabilising selection
Natural selection results in species that are better adapted to their environment
Anatomical, physiological and behavioural adaptations
3.7 Genetics, population, evolution and ecosystems
3.7.1 Inheritance
The genotype is the genetic constitution of an organism
The phenotype is the expression of this genetic constitution and its interaction with
the environment
There may be many alleles of a single gene
3.7.3 Evolution may lead to speciation
Variation in phenotype
Definitions and effects on genetic diversity
Process of natural selection leading to evolutionary change
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Adaptations in hominids
There are many adaptations that make humans the species they are today. These evolved
over
millions of years due to various selection pressures. We can characterise adaptations in
behavioural, physiological and behavioural.
Here are some examples of other human adaptations: Hominid = all the
species of humans and
Reduced teeth size great apes (both extinct
and alive today)
Reduced tailbone
Bipedalism (walking on two feet)
Varied diet
Bipedalism = the
Refined tool use condition of having
Reduced gut size two feet or using two
Sweat glands feet for locomotion
1. All hominids (all the great ape and human species past and present) show a tendency
for upright posture, however Homo sapiens are the only living hominid that are
habitually bipedal (walk on two legs all the time). Can you think of any reasons why
being bipedal would be adaptive and selected for?
Theories of bipedalism
Read the following article to find out about some current theories of bipedalism. Were your
ideas similar?
2. Name two features that are used to identify if a fossil specie was bipedal or not
3. Summarise one of the current main theories for how and why bipedalism evolved
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For example, here we will be looking at the feature brain size. The human fossil record
contains many human skulls from across the world and of different ages. Brain size is one
feature that can be measured and is estimated from the volume of the brain case (where the
brain sits in the skull). This is known as the cranial capacity and measured in cubic
centimetres.
Below is a table containing the measurements of brain sizes for different human fossils.
Time (mya)
2
2. What kind of selection is occurring here to create this trend? Explain your answer
If you need a reminder about selection, check the info box below!
Types of selection:
When there is variation in phenotype, selection can cause different changes in phenotype
frequency. You should have encountered different types of selection in AQA syllabus point
3.7.3. Here are some graphs to remind you of the different types of selection.
1 2 3
3.
Explain why individuals within a population of a species may show a wide range of
variation in phenotype
Explain how evolutionary change over a long period of time has resulted in a great
diversity of species.
Identifying the steps of natural selection in the evolution of lactose tolerance
Recall definitions and sources of genetic diversity
In humans our culture and biology have evolved together over time to create the species we
are today. One example of this coevolution is between the food we eat and our digestive
system; as our diet changed, our digestive system also changed in order to digest different
types of food, for instance milk.
Humans haven’t always been able to digest milk. 11,000 years ago, before animal
domestication, humans would stop producing lactase once they had been weaned off milk
as a child. This would mean humans stopped drinking milk as adult. However, this changed
once livestock was domesticated and humans started dairying.
Watch this video to see what happened after this. Click here.
2. In order for humans to be able to drink milk into adulthood, the mutant gene would have
been selected for and increased in frequency through natural selection. Arrange the
following steps to see how lactose tolerance evolved through the process of natural
selection.
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Genetic Diversity
3. What is the most suitable definition of genetic diversity? Need a little help?
A. The number of different genes in a person
Definitions for these terms can
B. The number of different alleles in a population be found in syllabus point 3.4.4
C. The number of different genes in a population and 3.7.2, or look at our glossary
A. Mutation – increases/decreases
B. Flow of alleles into the population through migration – increases/decreases
C. Genetic bottleneck – increases/decreases
D. Meiosis – increases/decreases
Genetic diversity can affect variation in phenotype, because genes are transcripted and
translated into proteins to produce the phenotype. But the phenotype is also influenced by
the environment. In the next section we will investigate one interaction between genes and
the environment that affects the phenotype produced (see 1.4 Phenotype and Environment
– Sickle cell disease case study).
15
Source 3: Prevalence of malaria among patients with and without sickle cell disease (SCD), by year of
hospital admission, from Komba et al (2009) Malaria as a Cause of Morbidity and Mortality in Children
with Homozygous Sickle Cell Disease on the Coast of Kenya. (LINK)
16
1. Describe and compare the trends in the percentage of people with malaria between
individuals with SCD and those without SCD.
Malaria is a parasitic organism found in many areas of the world. Malaria Falciparum, a type
of malaria caused by the parasite plasmodium falciparum, accounted for 99.7% of malaria
cases in 2018 [WHO 2020]. This parasite enters the human bloodstream through the bite of
a malarial vector such as the female anopheles mosquito (this is the most common form of
transmission). After entering the blood, the malarial trophozoites (baby protozoa) infects
red blood cells, changing their properties and causing them to stick together. Those who are
heterozygous for the sickle cell trait show some protection against malaria. This because
the mutation in the haemoglobin prevents the malarial trophozoite from changing the
properties of the red blood cell, preventing them from sticking together.
Source 4: cdc.gov
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2. Where would you predict incidences of Sickle Cell Disease to be highest? Explain why?
3. Based on what you have learnt, reinterpret the graph above, identifying the types of
selection involved and when to explain the pattern of percentage of people with malaria
in those with SCD.
This case study of sickle cell disease shows how mutations can be beneficial in some
contexts, and environments, and potentially harmful in others. Anthropologists and social
scientists often attempt to study diseases in socio-cultural contexts rather than seeing
inherited disease caused by mutations as binary. Understanding the nature of the mutation
and the environment and social context it is in can help create more effective
health interventions.
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Sections
2.1 Processes of evolution
2.2 Classifying human species
2.3 Extension Challenge: species in the hominin lineage
Suggested Timings
2.1 30-40mins
2.2 35-45mins
2.3 60mins
Syllabus Points
3.4 Genetic information, variation and relationships between organisms
3.4.4 Genetic diversity and adaptation
Natural selection results in species that are better adapted to their environment
3.4.5 Species and taxonomy
Definition of a species and processes of speciation
Taxonomy including the taxa kingdom, phylum, class, order, family, genus, species
Phylogenetic classification
Genetic sequencing
3.7 Genetics, population, evolution and ecosystems
3.7.2 Evolution may lead to speciation
Species exist as one or more populations
Concept of gene pool and allele frequency
3.7.3 Evolution may lead to speciation
Natural selection as differential survival and reproduction
Speciation through reproductive isolation
Variation in phenotype
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This worksheet will investigate the processes of evolution and show how natural selection
can lead to new species. To begin with watch this video from Khan Academy for an overview
of this topic.
Click here!
Speciation
1. Fill in the gaps in the following paragraph to test your knowledge on speciation:
Remember!
What does evolution look like?
The definition for evolution
in the AQA specification is
There are many definitions and ways of describing evolution. Often
this: change in allele
it depends on the scale you are looking at whether that is change frequencies in a population
at the level of the species, population, of allele frequencies.
Let’s look at some common misconceptions about evolution to deepen our understanding.
Below are some statements to do with the processes and outcomes of evolution.
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A. Evolution follows a straight line (is progressive), with more complex organisms being
the most advanced products of natural selection.
B. An ant is as evolutionarily advanced as a gorilla*. *This sentence means that two
C. Humans have evolved from chimpanzees. completely different species are
at the evolutionary stage they
D. Humans’ closest relatives are chimpanzees.
ought to be, given their
E. Natural selection would still be able to produce change environment. There is no “finish
without variation. line” for evolution!
F. Natural selection acts on phenotypes.
G. Each species has evolved to be adapted to their specific environment.
3. Which one of the following pictures describes better the way evolution via natural
selection occurs? Why?
B.
A.
Click here!
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Now that we understand how species are formed, let’s look at how species are classified.
1. Match the classification name to the correct taxa and highlight the binomial name.
Kingdom
Phylum Definitions for these
Class taxa can be found in the
glossary if you are stuck
Order
Family
Genus
Species
There are many ways to classify species. You could look at specific anatomical features, like
whether an organism has wings; for example, grouping organisms that have wings together
in one group and those without wings in another group. Using this logic, you could group
together butterflies, bats and birds. However, this doesn’t mean these species are closely
related to each other evolutionarily.
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Source 5: https://ib.bioninja.com.au/standard-level/topic-5-evolution-and-biodi/54-cladistics/structural-
evidence.html
2. Can you think of any other kinds of analogous characteristics? Write down two examples
Remember analogous characteristics often have the same function but have different
evolutionary origins and therefore will have different structures.
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Phylogeny
Homologous characteristics are used in phylogeny, the study of the evolutionary history of
groups of organisms. Phylogenetic trees are used to show evolutionary line of descent and
the relationship between species. Take a look at the phylogeny of the humans and our
closest relatives. This group of species are collectively called the hominids.
Hominids
5. Are Chimpanzees or Bonobos more closely related to humans (Homo sapiens)? Explain
your answer
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You can now even buy kits that let you send samples of spit to a lab that sequences your
DNA for you to understand your own genetic identity. Check out the surprising way saliva
has brought these six strangers together.
Click here!
6. From an evolutionary perspective, how is it possible that six people with different
phenotypes share almost the exact same genetic pool?
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Hominins
Hominids
Although Homo sapiens are the only remaining living hominin, we used to share the planet
with many other human species. Over the last century countless archaeological discoveries
have uncovered fossils of these now extinct species. Studying these fossils is important to
understand the story of our evolution.
Human evolutionists look at features, such as brain size, teeth structure, and bone structure,
in order to identify the fossil’s species and to see how they relate to other fossils. However,
this process can be tricky, and the fossil record is far from complete, so there is a lot of
debate in human evolution on the identity of certain fossils, how many hominin species
existed and what the exact evolutionary relationship is.
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We are now going to look at some of the more well-known and understood hominin species.
1. Complete the species profiles below by using information from the following website.
Click here!
Early hominins
Sahelanthropus tchadensis
Estimated age ____________________
Date discovered ____________________
Location ____________________
Main characteristics
Orrorin tugenensis
Estimated age ____________________
Date discovered ____________________
Location ____________________
Main characteristics
Ardipithecus ramidus
Estimated age ____________________
Date discovered ____________________
Location ____________________
Main characteristics
Australopiths
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Australopithecus afarensis
Estimated age ____________________
Date discovered ____________________
Location ____________________
Main characteristics
Australopithecus africanus
Estimated age ____________________
Date discovered ____________________
Location ____________________
Main characteristics
Robust Australopiths/Paranthropus
Estimated age ____________________
Date discovered ____________________
Location ____________________
Main characteristics
Homo erectus
Estimated age ____________________
Date discovered ____________________
Location ____________________
Main characteristics
Homo neanderthalis
Homo sapiens
Estimated age ____________________
Date discovered ____________________
Location ____________________
Main characteristics
Hopefully you are now more familiar with the hominin species!
2. Based on the estimated age of each fossil place these species groups onto the following
timeline of human evolution
Extra Resources
Virtual lab where you can interact with human fossils - https://africanfossils.org/
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Glossary
Adaptation
A change in structure, function, or behaviour by which a species or individual improves its chance of
survival in a specific environment.
Alleles
An allele is a variant form of a gene.
Analogous characteristics
Analogous structures are similar structures that evolved independently in two living organisms to
serve the same purpose.
Animalia
That one of the basic groups of living things that comprises either all the animals or all the
multicellular animals.
Anopheles
A mosquito of a genus which is particularly common in warmer countries and includes the
mosquitoes that transmit the malarial parasite to humans.
Bipedalism
The condition of having two feet or of using only two feet for locomotion.
Chordata
A chordate is an animal that belongs to the phylum Chordata, which is part of the Deuterostomes
kingdom (see definition below). The phylum (see definition below) Chordata includes a wide range of
organisms, as it is comprised of all vertebrates, which are organisms with a backbone, and many
invertebrates; organisms that don't have a backbone.
Class
In biological classification, class (Latin: classis) is a taxonomic rank, as well as a taxonomic unit,
a taxon, in that rank.
Disease Incidence
Incidence refers to the occurrence of new cases of disease or injury in a population over a
specified period of time. Although some epidemiologists use incidence to mean the number of new
cases in a community, others use incidence to mean the number of new cases per unit of
population.
Evolution
Evolution is change in the heritable characteristics of biological populations over successive
generations.
Family
In biology, a family is a taxonomic rank, or a taxon at that rank. Each family contains one or more
genera (see definition below – Genus).
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Gene
A base sequence of DNA that codes for the amino acid sequence of a polypeptide, or a functional
RNA.
Genetic Bottleneck
A genetic bottleneck occurs when a population is greatly reduced in size.
Genetic Diversity
The number of different alleles in a population.
Genetic Sequencing
Sequencing DNA means determining the order of the four chemical building blocks - called "bases" -
that make up the DNA molecule. The sequence tells scientists the kind of genetic information that is
carried in a particular DNA segment.
Genus
Genus, plural genera, biological classification ranking between family and species.
Haemoglobin
Hemoglobin, also spelled haemoglobin, iron-containing protein in the blood of many animals—in the
red blood cells (erythrocytes) of vertebrates—that transports oxygen to the tissues.
Heterozygous
A heterozygous individual is a diploid organism with two alleles, each of a different type.
Hominin
Any of the lineages of human beings, including the early human predecessors such as Homo erectus,
Homo habilis, Homo neanderthalensis, and Australopithecus species.
Homo sapiens
Homo sapiens, (Latin: “wise man”) the species to which all modern human beings belong. Homo
sapiens is one of several species grouped into the genus Homo, but it is the only one that is not
extinct.
Hominidae
Hominidae, in zoology, one of the two living families of the ape superfamily Hominoidea, the other
being the Hylobatidae (gibbons). Hominidae includes the great apes—that is, the orangutans (genus
Pongo), gorillas (Gorilla), and chimpanzees and bonobos (Pan)—as well as human beings (Homo).
Homologous characteristics
Characteristics in different organisms that are similar because they were inherited from a common
ancestor that also had that character.
Homozygous
A homozygous individual is a diploid organism with two alleles, each of the same type.
Interbreed
(With reference to an animal) breed or cause to breed with another of a different race or species.
"wolves and dogs can interbreed".
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Kingdom
In biology, kingdom is the second highest taxonomic rank, just below domain.
Lactase
An enzyme which catalyses the hydrolysis of lactose to glucose and galactose.
Lactose intolerance
Lactose intolerance is a common digestive problem where the body is unable to digest lactose, a
type of sugar mainly found in milk and dairy products. This is caused by an absence of lactase
enzyme in the body.
Locus
The specific location of a gene in a DNA molecule.
Malaria
An intermittent and remittent fever caused by a protozoan parasite which invades the red blood
cells and is transmitted by mosquitoes in many tropical and subtropical regions.
Mammalia
A class of vertebrate animals.
Mutation
A mutation is a change that occurs in our DNA sequence, either due to mistakes when the DNA is
copied or as the result of environmental factors
Natural Selection
Natural selection is the process through which populations of living organisms adapt and change.
Order
A taxonomic rank used in classifying organisms, generally below the class, and comprised of families
sharing a set of similar nature or character.
Parasite
A parasite is an organism that lives on or in a host organism and gets its food from or at the expense
of its host. There are three main classes of parasites that can cause disease in humans: protozoa,
helminths, and ectoparasites.
Phenotype
The term "phenotype" refers to the observable physical properties of an organism; these include the
organism's appearance, development, and behaviour.
Phylogenetic Tree
A branching diagram that shows the evolutionary relationships among different biological species
based on similarities and differences in their physical or genetic characteristics.
Phylogeny
Phylogeny, the history of the evolution of a species or group, especially in reference to lines of
descent and relationships among broad groups of organisms.
Phylum
A primary category in biological taxonomy especially of animals that ranks above the class and below
the kingdom.
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Plasmodium
Plasmodium is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and
insects. The life cycles of Plasmodium species involve development in a blood-feeding insect host
which then injects parasites into a vertebrate host during a blood meal.
Primates
Primate, in zoology, any mammal of the group that includes the lemurs, lorises, tarsiers, monkeys,
apes, and humans. In taxonomy, the order Primates is the highest order of mammals. They are
placental mammals with good eyesight and flexible hands and feet.
Protozoa
Protozoa are single celled organisms. They come in many different shapes and sizes ranging from an
Amoeba which can change its shape to Paramecium with its fixed shape and complex structure.
Sapiens
Homo sapiens is one of several species grouped into the genus Homo, but it is the only one that is
not extinct. Sapiens is the present participle of sapere or "to be wise".
Speciation
The formation of new and distinct species in the course of evolution. Speciation involves the splitting
of a single evolutionary lineage into two or more genetically independent lineages.
Species
A group of living organisms consisting of similar individuals capable of exchanging genes or
interbreeding. The species is the principal natural taxonomic unit, ranking below a genus and
denoted by a Latin binomial, e.g. Homo sapiens.
Taxon
A group of one or more populations of an organism or organisms that form a taxanomic unit of any
rank. (plural. Taxa)
Taxonomy
The classification of something, especially organisms. A scheme of classification.
Trophozoites
A growing stage in the life cycle of some sporozoan (type of protozoan) parasites, when they are
absorbing nutrients from the host.
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