DATE/ ROUTE/

PRECAUTION NURSING
TIME BRAND DOSAGE/ DRUG ADVERSE
ACTIONS INDICATION CONTRAINDI RESPONSIBILITI
ORDER NAME TIME INTERACTION EFFECT
CATIONS ES
ED INTERVAL

Zyprexa Chemical Short- term 10mg/ ODT ½ Antihypersentives: CNS: Use cautiously in  Monitor patients
effects: binds therapy for acute OPT in AM 1 may increase abnormal patients with for signs of NMS
February to dopamine manic episodes ODT at HS hypotensive effects. gait, heart disease, which is rare but
5, 2018 GENERIC and serotonin related to bipolar Monitor blood dizziness history of fatal
NAME: receptor, may I disorder. Long pressure closely. CV: chest seizures or  Monitor patient
antagonize term therapy for HALF LIFE: Alocohol use: may pain, conditions that for abnormal
Olanzapine adrenergic, schizophrenia, increase CNS tachycardia might lower the body temperature
muscarinic & agitation from 21 to 54 hours effects discourage EENT: seizure threshold regulation
CLASSIFIC hitaminergic schizophrenia using together. rhinitis, or hepatic  Monitor patient
ATION: receptors. and bipolar I ABSORPTION pharyngitis impairment. for weight gain
Therapeutic : GI: during treatment
Atypical effects: constipation Contraindicated  Tell patient to
antipsychotic relieves signs Food doesn’t EXCRETION: , dry mouth in patient’s avoid hazardous
and symptoms affect rate or About 57% in urine GU: hypersensitive to tasks until the
of psychosis. extent. About and 30% in feces or amenorrhea, the drug or any drugs CNS
40% of dose is metabolite. vaginitis. of its effects are
limited by first- components. known.
pass
metabolism.

57
DATE/
ROUTE/ DRUG ADVERS PRECAUTION
TIME BRAND NURSING
ACTIONS INDICATION DOSAGE/TIME INTERACT E CONTRAINDIC
ORDE NAME RESPONSIBILITIES
INTERVAL ION EFFECT ATIONS
RED

Fluanxol Acts as The 1mL IM q Drug-drug: CNS: Flupentixol should  Inform client that
Februar antagonist at maintenance of monthly CNS neurolepti not be given to Flupentixol can
y 15, various therapy of depression c patients who are occasionally cause a
2018 GENERIC dopamine, chronic with other malignant hypersensitive to dry mouth
NAME: serotonin, schizophrenic HALF LIFE: CNS syndrome the thioxanthenes.  Flupentixol can
adrenalin patients whose depressant EENT: It is also cause some skin to
Flupentixol and manifestations 35 hours including blurred contraindicated in become more
histamine do not include alcohol. vision, dry patients who have sensitive to sunlight
CLASSIFICATI receptor excitement, ABSORPTION: Some eyes, lens suspected or than usually in
ON: without agitation or antidepressa opacities. diagnosed  remind patient that
affecting the hyperactivity. Absorbed nt, some GI: subcortical brain before having any
Antipsychotics muscarinic following oral antihistamin constipatio damage, blood surgery, including
acetylcholin administration es n, dry dyscrasias, liver dental or emergency
e receptors. anxiolytics, mouth, damage, cerebro treatment, tell doctor
benzodiazepi anorexia, vascular or renal that you are taking
nes. hepatitis, insufficiency. flupentixol.
ileus.
GU:
EXCRETIO urinary
N: retention.

Urine and
feces

58
DATE/ ROUTE/
PRECAUTION
TIME BRAND DOSAGE/ DRUG ADVERSE NURSING
ACTIONS INDICATION CONTRAINDI
ORDE NAME TIME INTERACTION EFFECT RESPONSIBILITIES
CATIONS
RED INTERVAL

Februa Akineton Synthetic Parkinsonism PO 2mg 1tab The central Skin rashes, Untreated narrow 1. Assess for mental
ry 15, anticholinergi syndrome BID anticholinergic ataxia, angle glaucoma, status
2018 GENERIC c drug, especially to syndrome can impaired intestinal stenosis 2. Assess patient
NAME: blocks counter out occur when speech, or obstruction, response if
cholinergic muscular anticholinergic fatigue, mega colon, anticholinergic are
Biperidin responses in rigidity and HALF LIFE: agents such as dizziness, prostatic given
the CNS tremor, extra Akineton anxiety, hypertrophy, life 3. Assess for tolerance
CLASSIFIC pyramidal 24 hours (biperiden) are confusion, threatening over long term therapy,
ATION: symptoms. administered twitching tachycardia dosage may have to be
ABSORPTION concomitantly increased or change.
Anticholiner : with drugs that 4. Avoid activities that
gic have secondary require alertness may
Well absorbed anticholinergic cause dizziness and
from the GI actions, e.g., blurry vision.
tract. certain narcotic 5. Assess for
analgesics such parkinsonism
as meperidine,
the
phenothiazines
and other
antipsychotics, tri
cyclic
antidepressants,
certain anti
arrhythmic such
as the quinidine
salts,
and antihistamine
s.

59