This document lists various pediatric conditions and diseases, and for many provides the most common causes. Some of the most frequent entries include:
- Acute gastroenteritis is most commonly caused by rotavirus.
- Otitis media and sinusitis are most common in the first 2 years, often caused by rhinovirus or RSV.
- Pneumonia can be caused by various viruses like RSV, parainfluenza, and influenza depending on a child's age.
- Congenital hypothyroidism is most commonly caused by thyroid dysgenesis.
- Minimal change disease is the most common cause of nephrotic syndrome in children.
- Leukemia is the second
This document lists various pediatric conditions and diseases, and for many provides the most common causes. Some of the most frequent entries include:
- Acute gastroenteritis is most commonly caused by rotavirus.
- Otitis media and sinusitis are most common in the first 2 years, often caused by rhinovirus or RSV.
- Pneumonia can be caused by various viruses like RSV, parainfluenza, and influenza depending on a child's age.
- Congenital hypothyroidism is most commonly caused by thyroid dysgenesis.
- Minimal change disease is the most common cause of nephrotic syndrome in children.
- Leukemia is the second
This document lists various pediatric conditions and diseases, and for many provides the most common causes. Some of the most frequent entries include:
- Acute gastroenteritis is most commonly caused by rotavirus.
- Otitis media and sinusitis are most common in the first 2 years, often caused by rhinovirus or RSV.
- Pneumonia can be caused by various viruses like RSV, parainfluenza, and influenza depending on a child's age.
- Congenital hypothyroidism is most commonly caused by thyroid dysgenesis.
- Minimal change disease is the most common cause of nephrotic syndrome in children.
- Leukemia is the second
This document lists various pediatric conditions and diseases, and for many provides the most common causes. Some of the most frequent entries include:
- Acute gastroenteritis is most commonly caused by rotavirus.
- Otitis media and sinusitis are most common in the first 2 years, often caused by rhinovirus or RSV.
- Pneumonia can be caused by various viruses like RSV, parainfluenza, and influenza depending on a child's age.
- Congenital hypothyroidism is most commonly caused by thyroid dysgenesis.
- Minimal change disease is the most common cause of nephrotic syndrome in children.
- Leukemia is the second
2. Chronic granulomatous disease (CGD)= S. aureus 3. Neonatal Sepsis = group B Streptococcus, E. coli, and Listeria monocytogenes Pericarditis = viral (coxsackie B, adenovirus, influenza, echovirus) 4. Otitis Media / sinusitis most in = first 2 years (rhinovirus, RSV most often)/ Strep Pneumonia 5. Otitis externa = Pseudomonas aeruginosa (most common cause), S. aureus (second most common cause). 6. Osteomyelitis: °( S. aureus most common overall, in all) ° (Pseudomonas—puncture wound) °( More Salmonella in sickle cell (S. aureus still most common) 7. Septic arthritis: °( Almost all S. aureus) °( Most in young children; hematogenous; LE > UE and other parts of body) 8. Most common STD in developed countries = Chlamydia 9. Bronchiolitis = RSV 10. Croup = Parinfluenza Virus Type 1 11. Epiglottitis = Hemophilus influenza 12. Viral encephalitis = HSV 13. Viral ,meningitis = Enteroviruses 14. Bacterial Meningitis newborns = GBS/E. coli 15. Bacterial Meningitis > 2 months = S.Pneumonia 16. Bacterial Meningitis young adults = S.Pneumonia/ Neisseria meningitides 17. PNEUMONIA = a. Viral Pneumonia i. RSV . infants ii. . Parainfluenza . kids iii. Influenza virus . adults iv. ( Nonviral causes more common in children older than 5 years of age° Most—M. pneumoniae, and C. pneumoniae (not trachomatis)° S.pneumoniae most common with focal infiltrate in children of all ages 18. Erythema infectious = Paravirus B19 19. Measles = Paramyxovirus 20. Rubella = Rubella virus 21. Roseola = HHV-6 22. Chicken box = VZD 23. Hand Foot And Mouth disease = Coxsackie A virus 24. Acute renal failure in young children = Hemolytic Uremic Syndrome (HUS) (Most from E. coli) 25. Abduminal mass = Neonate- Hydronephrosis / <1year Neuroblastoma / > 1year Willms tumor 26. MC brain tumor = Benign Astrocytoma( infratentorial) / Medullablastoma 27. MCC of cerebral Palsy = Intrapartum asphyxia 28. Most common Skull fractures Injuries During Deliveries = linear Skull fracture 29. MCC of Death in Tetanus = Respiratory arrest 30. MC complication in Infectious mononucleosis(EBV kissing diz) = Splenic Hemorrhage 31. MC helminthes = Ascariasis ( MC symptoms cough , Hemoptysis) 32. MCC of Craniotabes = prematurity 33. Most common pattern of human malformation = Trisomy 21 (Down Syndrome) 34. Second most common pattern of human malformation = Trisomy 18 (Edwards Syndrome) 35. Klinefelter Syndrome (XXY) most common findings manifested at = puberty 36. Most common type Ehlers-Danlos Syndrome =type 1 37. most common teratogen to which fetus can be exposed = Alcohol 38. most common Failure-to-thrive (FTT) is = nutritional neglect 39. most common PHYSICAL ABUSE = Bruises 40. Immersion burns most common in = infants 41. Croup most common in = winter 42. Most common laryngeal airway anomaly and is the most frequent cause of stridor in infants and children = Laryngomalacia 43. Second most common cause of stridor = Congenital Subglottic Stenosis 44. Third most common cause of stridor = Vocal Cord Paralysis 45. most common site of foreign body aspiration in children age <1 year = Larynx (In children age >1 year, think trachea or right mainstem bronchus. 46. Most common life-limiting recessive trait among whites = CYSTIC FIBROSIS (CF) 47. most common cause of exocrine pancreatic deficiency in children= CF 48. most common cause of anaphylaxis seen in emergency rooms = Food allergic reactions 49. Most common reasons Anaphylaxis = In hospital—latex, antibiotics, IVIg (intravenous immunoglobulin), radiocontrast agents (Out of hospital—food (most common is peanuts) 50. Subacute and Chronic Atopic Dermatitis Most Commonly Affects the = Flexural Surfaces of Joints 51. Most common Selective IgA deficiency = B-cell defect 52. Chemical conjunctivitis most common in = first 24 hours of life 53. Most common primary malignant intraocular tumor = Retinoblastoma 54. Most common area of Epistaxis = anterior septum (Kiesselbach plexus) Digital trauma (nose picking; most common) 55. Polyps Most common cause is = cystic fibrosis 56. Most common congenital heart lesion = VSD common are membranous 57. Most common cyanotic lesion = TOF 58. Most common cyanotic lesion presenting in the immediate newborn period = TOGA (More common in infant of diabetic mother) 59. most common form of acquired heart disease worldwide = Acute Rheumatic Fever 60. Secondary HTN most common in = infants and younger children 61. most common congenital disorder associated with malabsorption is cystic fibrosis 62. Most common anomaly causing incomplete bowel obstruction with malabsorption is = malrotation 63. Most common cause of intestinal obstruction in neonate = Hirschprung Disease 64. most common cause of lower gastrointestinal bleeding in infancy = Anal fissure 65. most common cause of OBSTRUCTIVE UROPATHY is = hydronephrosis (due to ureteropelvic junction obstruction or multicystic kidney disease) 66. Most common chronic glomerular disease worldwide = IgA Nephropathy (Berger disease) 67. Most common cause of nephrotic syndrome in adults = Membranous Glomerulopathy 68. Most common cause of chronic glomerulonephritis in older children and young adults = Membranoproliferative Glomerulonephritis 69. Most common hereditary human kidney disease = POLYCYSTIC KIDNEY DISEASE Autosomal-Dominant Type (Adults) 70. most common form of persistent proteinuria in school-aged children and adolescents = Orthostatic type 71. most common nephrotic syndrome seen in children is =Steroid-sensitive minimal change disease 72. Minimal Change Disease Most common = between 2 and 6 years of age 73. Most common disorder of sexual differentiation in boys (more in preterm) = Undescended Testes 74. Most common cause of testicular pain over 12 years old = Testicular Torsion 75. Most common cause of testicular pain 2–11 years of age = Torsion of Appendix Testes 76. Most common surgically treatable cause of subfertility in men = Varicocele 77. Most common Congenital hypothyroidism is = thyroid dysgenesis (hypoplasia, aplasia, ectopia); no goiter 78. most common cause of Acquired hypothyroidism is = Hashimoto; thryroiditis 79. Most common cause of rickets = Vitamin D Deficiency 80. most common Congenital Adrenal Hyperplasia (CAH) = 21-Hydroxylase deficiency 81. Most common cause of Cushing Syndrome = Exogenesis 82. Most common cause of insulin resistance is childhood obesity = Type 2 DM 83. Most common adolescent hip disorder = Slipped Capital Femoral Epiphysis (SCFE) 84. Most common genetic cause of osteoporosis = OSTEOGENESIS IMPERFECTA 85. Most common Congenital Pancytopenia = Fanconi anemia (spontaneous chromosomal breaks) 86. most common acquired cause of bleeding disorders in children is = thrombocytopenia 87. Most common hereditary bleeding disorder = von Willebrand Disease (vWD) 88. most common presenting sign of Hodgkin Lymphoma = Painless, firm cervical or supraclavicular nodes () 89. Second most frequent malignancy in children; mortality 45% = Brain tumer 90. Most common Brain tumer = Infratentorial Tumors (Classic site—cerebellum) 91. Second most common malignant abdominal tumor = Wilms Tumor 92. Most common site of Pheochromocytoma = adrenal medulla 93. most common seizure usually present within 12–24 hours after birth= Hypoxic ischemic encephalopathy 94. Most common Complication of bacterial meningitis is = hearing loss 95. most common presentation of viral meningitis is = cerebellar ataxia and acute encephalitis. 96. Most common cause of lymphadenitis lasting >3 weeks = Bartonella (Cat-Scratch Disease) 97. Most common presentation of Cryptococcus neoformans = Pneumonia 98. Most common complication of Measles is = otitis media 99. mumps Most common in = winter/spring 100. most common complication of mumps = Meningoencephalomyelitis 101. Most common symptom of Ascariasis is = pulmonary disease—cough and blood- stained sputum 102. most common symptoms of Enterobiasis = itching and restless sleep and no eosinophilia 103. Most frequent congenital gastrointestinal anomaly = Meckel Diverticulum 104. Minimal Change Disease = Infection is the major complication (Most frequent is spontaneous bacterial peritonitis (S. pneumoniae most common) 105. Most frequent tumor of the optic nerve = Optic nerve glioma 106. Most TORCH infections are acquired in = first or second trimester. Most infants have IUGR 107. Congenital Syphilis = Treponema in scrapings (most accurate test) from any lesion or fluid, serologic tests a. Most helpful specific test is IgM-FTA-ABS b. Treatment—penicillin 108. Trisomy 18 (Edwards Syndrome) Most do not survive in = first year 109. Beckwith-Wiedemann Syndrome = Pancreatic beta cell hyperplasia—excess islets → hypoglycemia; hypoglycemia may be refractory; glucose control most important initial management 110. Most commercial formulas are = cow-milk–based with modifications to approximate breast milk 111. Osteosarcoma most common in = Midshaft of long bones 112. Ewings Sarcoma most common in = Metapheses of long bones 113. Most common type of cerebral Palsy = Pyramidal or spastic type 114. MCC of congenital diaphragmatic hernia = Buchdalick ( posterior ) 115. MCC of bowel obstruction in first 2 years = Intussusception 116. Most common GI emergency in neonates = NEC ( Comp.Short bowel synd. And intist.Stricture 117. Most specific sepsis screen test = neutropenia ( sensitive – I:T) 118. Most sensitive measure of volume state = HR 119. varicella infection = Most people over 18 years of age even without a reliable history of varicella infection, will still be immune 120. Bronchiolitis almost all children infected by age= <2 years, most severe at age 1–2 months in winter months. 121. Umbilical Hernia most close by = 5 years 122. Aortic Stenosis Most are = bicuspid aortic valve—usually asymptomatic in children 123. Valvular disease most important complication (mitral, aortic, tricuspid) in = Acute Rheumatic Fever 124. Most important early issue in Cleft Lip and Palate is = feeding (special nipple needed) 125. Chronic Diarrhea and Malabsorption = a. Fat i. Most useful screening test is stool for fat (Sudan red stain) ii. Confirm with 72-hour stool for fecal fat (gold standard for steatorrhea) iii. Steatorrhea is most prominent with pancreatic insufficiency; all require a sweat chloride iv. Serum trypsinogen is also a good screen (reflects residual pancreatic function) 126. Jejunal or Ileal Atresia Most present on = the first day of life. 127. Most frequent congenital gastrointestinal anomaly = Meckel Diverticulum 128. Most important primary treatment in IgA Nephropathy (Berger disease) = is blood pressure control. 129. Precocious Puberty= (Girls—sexual development <8 years old Boys—sexual development <9 years old) Most common etiologies: - Sporadic and familial in girls /Hamartomas in boys 130. The most serious sequelae of Kawasaki disease are = cardiac-related.( important test is 2D echocardiogram; repeat at 2–3 weeks and, if normal, at 6–8 weeks. Also get ECG, follow platelets.) 131. Immune Thrombocytopenic Purpura (ITP) Most resolve within = 6 months 132. Best initial diagnostic test for Respiratory distress syndrome (RDS) = chest radiograph (Best initial treatment oxygen, Most effective treatment—intubation and exogenous surfactant administration) 133. best test For Transient tachypnea of the newborn (TTN) / Meconium aspiration is = Chest x-ray for 134. best test for Diaphragmatic hernia is = Postnatal x-ray (Best initial treatment— immediate intubation in delivery room for known or suspected CDH, followed by surgical correction when stable (usually days). 135. Best diagnosis for Herpes Simplex=: PCR, any body fluid (Best treatment: IV acyclovir ASAP) 136. best tool to determine patterns of growth = Growth chart is the. 137. best growth curve indicator for acute malnutrition = Weight/height <5th percentile is the single 138. best clinical indicator for measure of under- and overweight = BMI 139. best test for CF = Sweat test 140. Best initial test for Diagnosis Orbital cellulitis = CT scan with contrast of orbits and surrounding area 141. best test for diagnosing all cardiac congenital defects is =.Echocardiography is the 142. best test for Gastroesophageal Reflux Disease (GERD) = Esophageal pH monitoring a. H2-receptor antagonist (ranitidine, cimetidine, famotidine)—first-line with overall best safety profile b. Proton pump inhibitor (omeprazole, lansoprazole, pantoprazole)—most potent for severe reflux and esophagitis 143. best test Pyloric Stenosis is = ultrasound 144. Testes should be descended by 4 months of age or will remain undescended; surgery best performed at = 6 months 145. best test for Cushing Syndrome is = Dexamethasone-suppression test single 146. SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)= a. Best screen: ANA b. Best test: anti-dsDNA (more specific for lupus; reflects disease activity) c. AntiSmith = Specific 147. best test for Sickle Cell Anemia = Hb electrophoresis 148. Best test Acute Lymphoblastic Leukemia is = bone marrow aspirate → lymphoblasts 149. best initial test for all BRAIN TUMORS = Head CT scan (MRI best imaging test overall) 150. Best initial test for Wilms Tumor is =ultrasound –(Abdominal CT scan confirmatory test) 151. Most tumors can be localized by = CT scan (best initial test) and MRI 152. Best screen for Wilson Disease = serum ceruloplasmin (decreased) 153. best test For viral meningitis = PCR of CSF is the 154. Best initial diagnostic test for RDS= chest radiograph 155. first-line therapy for Allergic Rhinitis = Antihistamines 156. first-line therapy for otitis media = amoxicillin (high dose) (Alternate first-line drug or history of penicillin allergy = azithromycin 157. first-line therapy for Sinusitis = amoxicillin (Alternative—cefuroxime axetil, cefpodoxime, azithromycin) 158. Most useful screening test for Chronic Diarrhea and Malabsorption is = stool for fat (Sudan red stain) 159. Initial presentation Neuroblastoma often as = metastasis 160. Primary initial pulmonary hallmark for RSD is = hypoxemia (Most accurate diagnostic test—L/S ratio (part of complete lung profile; lecithinto- sphingomyelin ratio) 161. Hallmark in Toxoplasmosis =hydrocephalus with generalized calcifications and chorioretinitis 162. Hallmark in Rubella =the classic findings of cataracts, deafness, and heart defects 163. Hallmark in CMV = microcephaly with periventricular calcifications; petechiae with thrombocytopenia 164. Hallmark in Herpes =skin vesicles, keratoconjunctivitis, acute meningoencephalitis 165. Hallmark in Syphilis =osteochondritis and periostitis; skin rash involving palms and soles and is desquamating; snuffles (mucopurulent rhinitis) 166. Most food allergies are = egg, milk, peanuts, nuts, fish, soy, wheat, but any food may cause a food allergy. 167. most common presenting sign for Hodgkin = Painless, firm cervical or supraclavicular nodes Lymphoma 168. most obvious manifestation in Cerebral Palsy is = impaired ability of voluntary muscles (rigidity and spasticity). 169. In Spinal Muscle Atrophy (SMA) Treatment is supportive; there is no cure most die in first = 2 years of life 170. MCC of limp = Trauma 171. MC joint in septic Arthritis = Hip (Adults = knee) 172. Red Current jelly = intussusception 173. Drug of choice for lead poisioning in children = Sucomir ( in adults Penicillamine ) 174. Drug of choice for impetigo = penicillin 175. Adrenal Medullary Tumor . Children = Neuroblastoma (Pheochromocytoma: adults) 176. Cardiac 1ry Tumor . Child = . Rhabdomyoma . associated w/ Tuberous sclerosis 177. Cause of Death in premature = NRDS = hyaline membrane disease 178. Cause of Death in SLE pts. = . Lupus Nephropathy Type IV (Diffuse Proliferative) = Renal Disease 179. Non Hodgkin.s Lymphoma =. Follicular small clear cell 180. Pt. with Hodgkin.s =. Young Male (except Nodular Sclerosis type . Female) ( Reed Strenberg cells) 181. Pt. with Minimal Change Disease = Young Child 182. Site of Diverticula = Sigmoid Colon 183. Thyroid CA=. Papillary CA 184. Tumor of Infancy =. Benign vascular tumor = port wine stain = Hemangioma 185. Type of Hodgkin.s =. Mixed Cellularity (versus: lymphocytic predominance, lymphocytic depletion, nodular sclerosis) 186. Type of Non-Hodgkin.s = Follicular, small cleaved 187. Type of Soft Tissue Tumor of Childhood = Rhabdomyosarcoma 188. Bug in Otitis Media & Sinusitis in Kids =. Strep. Pneumoniae 189. Complication of COPD =. Pulmonary infections 190. Enzyme deficiency = 21 hydroxylase - 95% of CAH 191. Hypertension children = Renal disease; cystic disease, Wilm's tumor 192. Hypopituitarism = kids Craniopharyngioma 193. MC muscle dystrophy in children = Becker.s Muscular Dystrophy (Similar to Duchenne, but less severe 194. Duchenne Muscular Dystrophy = Deficiency of dystrophin protein → MD X-linked recessive 195. Erb-Duchenne Palsy = Trauma to superior trunk of brachial plexus Waiter.s Tip 196. Lesch-Nyhan = HGPRT deficiency/ Gout, retardation, self-mutilation 197. Ehler.s-Danlos = Defective collagen 198. Felty.s Syndrome = Rheumatoid arthritis, neutropenia, splenomegaly 199. Goodpasture.s = Autoimmune: ab.s to glomerular & alveolar basement membranes. Seen in men in their 20.s 200. Guillain-Barre = Polyneuritis following viral infection/ autoimmune (ascending muscle weakness & paralysis; usually self-limiting) 201. Hashitoxicosis = Initial hyperthyroidism in Hashimoto.s Thyroiditis that precedes hypothyroidism 202. Buerger.s Disease = Acute inflammation of medium and small arteries of extremities → painful ischemia → gangrene Seen almost exclusively in young and middle-aged men who smoke. 203. Berger.s Disease = IgA nephropathy causing hematuria in kids, usually following infection 204. Henoch-Schonlein purpura = Hypersensivity vasculitis = allergic purpura. Lesions have the same age. 1. Hemmorhagic urticaria (with fever, arthralgias, GI & renal involvement) 2. 83. Associated with upper respiratory infections 205. Kawasaki most Affect = Medium size vessels ( especially coronaries ) 206. Hirschprung.s Disease = Aganglionic megacolon 207. Rotor Syndrome = Congenital hyperbilirubinemia (conjugated) (Similar to Dubin- Johnson, but no discoloration of the liver) 208. Horner.s Syndrome = Ptosis, miosis, anhidrosis (lesion of cervical sympathetic nerves often 2 to a Pancoast tumor) 209. Reye.s Syndrome =. Microvesicular fatty liver change & encephalopathy 2 to aspirin ingestion in children following viral illness, especially VZV 210. Pancoast Tumor = Bronchogenic tumor with superior sulcus involvement → Horner.s Syndrome 211. Raynaud.s = Disease: recurrent vasospasm in extremities = seen in young, healthy women i. = Phenomenon: 2 to underlying disease (SLE or scleroderma)