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Voluntary Non-Remunerated Blood Donations To Ensure Blood Safety in The WHO South-East Asia
Voluntary Non-Remunerated Blood Donations To Ensure Blood Safety in The WHO South-East Asia
1. Introduc,on
• WHO aims to improve transfusion services worldwide, especially in low- and
middle-income countries (LMICs).
• This report focuses on the status of voluntary blood dona7on and related
ac7vi7es in the WHO South-East Asia Region, based on 2018 data.
• The goal is to collect data on na7onal blood systems, iden7fy gaps, and
opportuni7es for improvement in voluntary blood dona7ons.
• Global Training and Educa,on Sharing: In the modern world, which is ogen
referred to as a global village, training and educa7on can be shared among countries.
Online training and webinars have made it easier for individuals to access educa7on and
training opportuni7es. Professional socie7es like the Asian Associa7on of Transfusion
Medicine (AATM) can sponsor candidates for hands-on training in developed countries,
offering valuable educa7onal opportuni7es.
• Centraliza,on of Blood Transfusion Services (BTS): Centralizing blood
transfusion services can help address the gaps in human resource availability.
Centraliza7on can lead to more efficient and effec7ve u7liza7on of trained human
resources. Sri Lanka is cited as an example of a country that has successfully
demonstrated this approach in recent 7mes.
• Job Opportuni,es for Specialized Professionals: Professionals with specialized
knowledge and skills in the field of Transfusion Medicine, par7cularly in therapeu7c
apheresis and cellular therapies, have excellent job opportuni7es available to them in
various parts of the world. This specializa7on opens up career prospects and allows
professionals to contribute to the field on a global scale.
These opportuni7es reflect the poten7al for collabora7on, training, centraliza7on, and
career advancement within the field of blood transfusion services in the South-East Asia
Region and beyond.
• Origins of Safe Blood Donor Concept: The concept of a safe blood donor has
been present since the incep7on of the "mobile donor service" at the Bri7sh Red Cross
Blood Transfusion Service in 1921. During this service, blood grouping and syphilis
tes7ng were performed for the panel of donors included.
• Regular Repeat Donors: Regular repeat donors are considered the safest blood
donors for several reasons:
• They are screened for markers of transfusion-transmissible infec7ons (TTIs)
repeatedly over 7me, during each blood dona7on. This frequent screening reduces the
likelihood of donors being in the "window period" of TTIs, where infec7ons may not yet
be detectable.
• Studies have shown that regular repeat donors have a lower prevalence of TTIs,
such as an7bodies to HIV-1 and/or 2, an7bodies to hepa77s C virus (HCV), and surface
an7gen of hepa77s B virus (HBsAg), compared to replacement first-7me donors.
• Regular blood donors are typically well-informed about the tes7ng procedures
for TTIs conducted by blood centers. They also have a greater awareness of the risk
factors associated with TTIs, thanks to the repeated pre-dona7on counseling they
receive over the donor cycle.
This informa7on highlights the cri7cal role played by regular repeat donors in ensuring
the safety of the blood supply and reducing the risk of TTIs. Their awareness,
commitment, and consistent screening contribute to a safer blood dona7on process.
• Inform the Donor about the Recipients: Let the blood donor know
where their blood and blood components are being transfused. This creates a sense of
purpose and connec7on for the donor.
• Appeal for Repeat Dona,ons: Encourage the donor to become a
repeat donor by emphasizing the importance of dona7ng regularly. Ignite the passion
for regular blood dona7on.
• Highlight Impact: Share stories of the posi7ve impact of blood
transfusion, such as the success stories of regular blood transfusion in trea7ng
condi7ons like thalassemia. Demonstra7ng the real-world impact of dona7ons can
mo7vate donors.
• Show Apprecia,on: Express apprecia7on and gra7tude to the
blood donor. Thank the donor at least three 7mes during the blood dona7on process.
Use various communica7on channels such as SMS, WhatsApp, emails, and social media
planorms like Twicer, Facebook, and Instagram to follow up with thanks.
• Request Future Dona,ons: Ask for the next blood dona7on using
the aforemen7oned communica7on channels. Encourage donors to schedule their next
dona7on.
• Convenient Dona,on: Make it convenient for donors to donate by
reaching out to their workplaces or homes. Conduct outdoor blood dona7on drives in
collabora7on with resident welfare associa7ons, market welfare associa7ons, and
religious organiza7ons, where donors are likely to par7cipate during their free 7me.
• Minimize Wai,ng Time: Reduce donor wai7ng 7mes as much as
possible to make the dona7on process efficient and comfortable.
• Address Donor Adverse Reac,ons: Address any adverse reac7ons
experienced by donors promptly and professionally to ensure their well-being.
• Manage Donor Anxiety: Provide audio-visual engagement or other
distrac7ons to reduce donor anxiety during the dona7on process.
• Donor Deferral Management: Explain the reasons for donor
deferral and encourage the re-induc7on of temporarily deferred donors ager the
wai7ng period has passed.
• Enhance Personal Connec,on: Foster a strong personal connec7on
between donors and the service staff. A posi7ve donor experience can encourage
con7nued par7cipa7on.
These strategies aim to not only recruit new blood donors but also retain them as
regular donors. By focusing on donor engagement, convenience, and apprecia7on,
blood dona7on centers can create a suppor7ve environment that encourages ongoing
par7cipa7on in blood dona7on programs.
The current status of blood collec7on and the propor7on of Voluntary Non-
Remunerated Donors (VNRDs) in the 11 Member countries of the South-East Asia
Region is as follows:
• Eight out of the 11 Member States have more than 75% voluntary blood
dona7on.
• The Democra7c People’s Republic of Korea, Sri Lanka, and Thailand have
achieved a remarkable 100% blood supply from VNRDs.
• However, three countries, namely Maldives, Bangladesh, and Timor-Leste, have
less than 50% VNRDs, indica7ng a greater reliance on other types of donors.
This data suggests that a significant por7on of blood collec7on in the South-East Asia
Region comes from voluntary donors, reflec7ng a posi7ve trend toward safe and
sustainable blood supplies in many countries within the region. However, there is s7ll
room for improvement in those countries where the propor7on of VNRDs is rela7vely
low. Efforts to encourage voluntary non-remunerated blood dona7on and raise
awareness about its importance could further strengthen blood transfusion services in
these countries.
The current status of donor types and demographic characteris7cs in the South-East
Asia Region is as follows:
• Donor Types:
• Sri Lanka is the only country in the region that relies en7rely on voluntary blood
dona7on, except for autologous dona7ons.
• Bangladesh, Bhutan, Nepal, India, Indonesia, and Thailand report the prac7ce of
replacement, family, and directed blood donor systems.
• The paid donor system is not in prac7ce in any of the countries, which is a
posi7ve measure for blood safety.
• Gender of Blood Donors:
• There is significant varia7on in the gender distribu7on of blood donors across
Member States.
• Bangladesh and India have a male predominance of blood donors, with a ra7o of
95% males to 5% females.
• The gender distribu7on becomes more balanced in Indonesia, Nepal, and Sri
Lanka, with a ra7o of approximately 70% males to 30% females.
• In Bhutan, the gender distribu7on is close to 60% males to 40% females.
• Thailand stands out with a female preponderance of donors, where the
propor7on of female to male blood donors is 56% versus 46%.
• Age Criteria for Blood Dona,on:
• Different countries in the region have varying age criteria for blood dona7on.
• Bangladesh, Bhutan, Sri Lanka, and Thailand allow blood dona7on between 18
years and 60 years, with Thailand allowing those aged 17 years with parental consent.
• India and Nepal permit blood dona7on between 18 and 65 years, but in India,
first-7me blood donors can donate only up to the age of 60 years.
• Indonesia allows blood dona7on between 17 years and 65 years.
• Age Distribu,on of Blood Donors:
• All seven par7cipant countries have the highest number of blood donors in the
age group of 21 to 59 years.
• Bhutan, India, and Sri Lanka have more than 20% of blood donors under the age
of 20 years.
• Bangladesh and Nepal have more than 10% of blood donors under the age of 20
years.
• Nepal also has 5% of blood donors above the age of 60 years.
These demographic characteris7cs provide valuable insights into the profile of blood
donors in the South-East Asia Region, indica7ng varia7ons in donor types, gender
distribu7on, and age criteria across different countries. It also highlights the importance
of understanding and targe7ng specific demographics for effec7ve donor recruitment
and reten7on strategies.
Donor data management involves the collec7on, storage, and analysis of informa7on
related to blood donors. It plays a crucial role in maintaining a transparent and efficient
blood dona7on system. There are various types and methods of donor data
management:
• Na,onal Surveys among Blood Centres: This involves conduc7ng
surveys at the na7onal level to collect data from different blood centers and
organiza7ons involved in blood dona7on. These surveys aim to gather informa7on on
donor profiles, dona7on pacerns, and other relevant data.
• Comprehensive Research Data: Donor data can be collected
through comprehensive research studies focused on blood dona7on. These studies may
involve analyzing donor demographics, dona7on frequency, mo7va7ons, and other
factors that influence blood dona7on.
• Data Analysis by Individual Hospitals and Blood Centres: Hospitals
and individual blood centers ogen collect and analyze data specific to their opera7ons.
This data can include donor registra7on informa7on, dona7on history, and tes7ng
results. Analyzing this data helps in managing donor rela7onships and understanding
local donor trends.
• Donor Database Warehouse: A donor database warehouse is a
centralized repository that stores donor-related informa7on from mul7ple sources. It
allows for efficient data management and retrieval, making it easier to maintain
complete donor profiles, track donor behavior, and ensure compliance with tes7ng
standards.
The main applica7ons and advantages of donor data management include maintaining
complete donor profiles, understanding the epidemiology of donors and recipients,
facilita7ng coordina7on between blood centers, adhering to uniform tes7ng standards,
improving blood matching, addressing blood shortage issues, conduc7ng research on
donor and product risk factors, formula7ng and upda7ng donor guidelines, and
designing quality indicators for blood dona7on.
By u7lizing donor data management effec7vely, blood centers and organiza7ons can
enhance their ability to provide safe and sufficient blood products to meet the needs of
pa7ents and improve overall blood transfusion prac7ces.
Donor data are stored and retrieved using various methods and systems, depending on
the region and the level of organiza7on. Some common approaches to donor data
storage and retrieval include:
• Centralized Donor Databases: In European countries and some
other regions, centralized donor databases or "donor database warehouses" have been
established. These databases link comprehensive data of donors and recipients from
various sources. Individual hospitals and blood banks regularly collect and update data
on donors and transfusion recipients, which is then analyzed at a central level. Examples
include the Dutch Transfusion Data warehouse (DTD) project, Scandinavian Dona7ons
and Transfusions Database (SCANDAT) from Sweden and Denmark, and others.
• Data Collec,on and Valida,on: Donor data are typically collected
and managed by teams of experts, including researchers from the field of transfusion
medicine, data modeling specialists, and informa7on technology professionals. Uniform
data collec7on formats are ogen designed and shared with par7cipa7ng centers to
ensure consistency. Data valida7on processes are put in place to minimize discrepancies
and errors in the collected informa7on.
Centralized vs. Local/Regional Donor Data Management:
The donor data management system can be organized at different levels, each with its
own advantages and disadvantages:
Centralized Na,onal-Level Data Collec,on:
• Advantages:
• Enables centralized collec7on, management, and evalua7on of data.
• Facilitates the formula7on of na7onal-level policies and donor vigilance
programs.
• Consistency in data collec7on and repor7ng.
• U7lizes data from various regional centers for a comprehensive na7onal
perspec7ve.
• Challenges:
• Requires capacity-building in terms of staff training and data management
sogware.
• Addresses data privacy and security concerns.
• Ensures adequate internet connec7vity at all par7cipa7ng centers.
• May face difficul7es in linking data from diverse regional blood centers.
• May not account for regional varia7ons in epidemiology and demography.
Local/Regional-Level or Individual Blood Center Data Management:
• Advantages:
• Data collec7on at a more localized level, easier to manage.
• Promotes staff mo7va7on and awareness.
• Requires fewer resources compared to a na7onal-level system.
• Challenges:
• Data may not be easily extrapolated or applicable at the na7onal level.
• Limited scope for comprehensive na7onal policies.
• Relies on individual center's capacity and resources.
The choice between centralized and local/regional data management depends on the
specific goals and resources of the blood dona7on organiza7on or country, as well as
the need for both local and na7onal-level insights into donor and recipient informa7on.
How has donor data management helped in improving donor recruitment and
reten,on, donor and recipient safety – look-back in case of TTI?
Donor data management plays a crucial role in improving various aspects of blood
dona7on and transfusion systems. Here are some key contribu7ons and benefits of
donor data management:
• Promo,ng Voluntary Blood Dona,on: Donor data management
creates awareness about the importance of voluntary blood dona7on by highligh7ng
the gap between the na7on's blood supply needs and the number of dona7ons
required. This mo7vates voluntary blood donors to ac7vely par7cipate and surpass the
number of replacement dona7ons, which are ogen enrolled through passive
recruitment ac7vi7es.
• Strengthening Recruitment and Reten,on Strategies: Donor data
management provides valuable insights into the donor popula7on's epidemiology. This
informa7on helps in designing and implemen7ng effec7ve donor recruitment and
reten7on strategies. It assists in dissemina7ng informa7on about blood dona7on,
conduc7ng training for blood donor recruiters, and ini7a7ng donor apprecia7on
programs.
• Monitoring the Transfusion Chain: Donor data management helps
in monitoring the en7re transfusion chain, from donor recruitment to recipient
outcomes. This comprehensive view allows for becer management of blood resources
and ensures the safety of both donors and recipients.
• Research Data: Donor data can be a valuable source for research
across the transfusion chain. It helps in studying various aspects of blood dona7on and
transfusion, leading to evidence-based prac7ces and policies.
• Government Sensi,za,on: Centralized donor management systems
can raise awareness among government authori7es about blood donor-related issues.
This awareness can result in increased governmental investment in blood management
and infrastructure.
• Iden,fying Challenges: Donor data analysis can reveal challenges in
donor recruitment and reten7on. For example, it can iden7fy barriers to recrui7ng
female donors, reasons for a high percentage of first-7me donors, and issues with
replacement donor programs. This informa7on is essen7al for developing targeted
strategies and policies.
• Transfusion Safety: Donor data management contributes to
transfusion safety by reducing errors in transfusion-transmiced infec7on (TTI) tes7ng. It
supports staff training, consolida7on of laboratory centers, and the implementa7on of
highly sensi7ve screening tests. It also enables look-back studies for TTIs and efficient
laboratory prac7ces.
• Data Storage for Verifica,on: Some blood centers, like the Korean
Red Cross, store donor data for extended periods. This allows real-7me verifica7on of
donor eligibility and facilitates informa7on dissemina7on regarding urgent blood
requirements and rare blood groups.
• Interna,onal Collabora,ons: Projects like DOMAINE (Donor
Management IN Europe) bring together blood establishments from mul7ple countries to
collaborate on donor management. This interna7onal collabora7on enhances the
exchange of best prac7ces and experiences in donor recruitment and reten7on.
In summary, donor data management is a cri7cal component of a safe and efficient
blood dona7on and transfusion system. It supports recruitment, reten7on, safety,
research, and policymaking efforts, ul7mately helping blood centers meet the
challenges and demands of their popula7ons.
Quality indicators in voluntary blood dona7on are crucial tools for monitoring and
improving blood dona7on ac7vi7es. These indicators provide insights into the efficiency
and safety of the blood dona7on process. They are typically categorized into three main
types: structural indicators, process indicators, and outcome indicators. Here's how they
help in monitoring blood dona7on ac7vi7es:
• Structural Indicators: These indicators focus on the organiza7onal
and infrastructural aspects of blood dona7on programs. They include:
• Blood Donor Profile: These indicators encompass data on the gender ra7o of
donors (male to female), age distribu7on of donors, and the propor7on of first-
7me/repeat donors. Monitoring these indicators helps in understanding the
demographics of the donor pool.
• Donor Types: This includes informa7on on voluntary donors, replacement
donors, and family donors. It helps in assessing the reliance on voluntary, non-
remunerated donors.
• Blood Stocks: Monitoring blood stocks is essen7al for ensuring an adequate and
7mely supply of blood components.
• Dona,on Camps: Tracking the number of voluntary blood dona7on camps helps
assess the outreach and accessibility of dona7on opportuni7es.
• Donor Registries: Maintaining registries of voluntary and rare blood donors helps
in efficient donor management.
• Process Indicators: These indicators focus on the steps and
processes within the blood dona7on system. They include:
• Donor Deferral Rate: This indicator measures the rate at which donors are
temporarily deferred, usually due to medical reasons. High deferral rates may indicate
issues with donor eligibility criteria or donor educa7on.
• TTI Prevalence Rate: Monitoring the prevalence of transfusion-transmiced
infec7ons (TTIs) among donors helps assess the safety of donated blood.
• Donor Adverse Events: Tracking adverse events experienced by donors during or
ager dona7on helps in ensuring donor safety.
• CUE (Confiden,al Unit Exclusion): CUE refers to the removal of donated blood
units from the supply due to concerns about donor health or eligibility. High CUE rates
may indicate issues with donor screening.
• Donor No,fica,on and Recall: Monitoring whether donors are informed of their
test results and recalling poten7ally infected donors is essen7al for preven7ng TTIs.
• Outcome Indicators: These indicators assess the overall impact of
blood dona7on ac7vi7es and donor sa7sfac7on. They include:
• Donor Feedback and Complaints: Gathering feedback and addressing donor
complaints help improve the donor experience and the quality of services.
• Donor Sa,sfac,on: Assessing donor sa7sfac7on levels helps in understanding the
overall donor experience and iden7fying areas for improvement.
• Correc,ve Measures: Monitoring whether correc7ve ac7ons are implemented in
a 7mely manner in response to iden7fied issues is essen7al for con7nuous
improvement.
Quality indicators enable blood banks and health authori7es to iden7fy areas of
concern, implement correc7ve ac7ons, and measure the effec7veness of quality
improvement efforts. They also facilitate comparisons between different regions and
countries, enabling benchmarking and the development of effec7ve donor policies.
Ul7mately, quality indicators play a vital role in ensuring the safety and sufficiency of
the blood supply.
Experience from different parts of the world, how they have improved voluntary
blood dona,on
The role of voluntary blood donors in mo7va7ng others and sefng an example cannot
be overstated. Here are some key points from the provided informa7on:
• Role Models: Voluntary blood donors can serve as role models for
others in their communi7es. When people see their peers dona7ng blood willingly and
without remunera7on, it can inspire them to do the same.
• Influence of Organiza,ons: Social, religious, and educa7onal
organiza7ons have the poten7al to promote voluntary non-remunerated blood
dona7on (VNRD) effec7vely. They can leverage their influence and networks to raise
awareness about the importance of VNRD and organize dona7on drives.
• Military and Paramilitary Forces: These forces play a unique role in
mo7va7ng blood dona7on. Their patrio7c values and dedica7on to the na7on can
inspire others to contribute to the well-being of the community by dona7ng blood.
• Financial Support: Adequate funding is essen7al to support blood
services and VNRD ini7a7ves. Without sufficient financial resources, it can be
challenging to create and maintain the infrastructure needed for safe and efficient blood
collec7on and distribu7on.
• Poli,cal Will: Poli7cal commitment and support are crucial for the
success of VNRD programs. Governments should priori7ze blood services and enact
policies and regula7ons that promote voluntary dona7on while discouraging
remunerated or professional dona7on.
• Educa,on: Educa7ng the general public about the importance of
VNRD and dispelling myths and misconcep7ons surrounding blood dona7on is essen7al.
Educa7onal campaigns can help create a culture of voluntary dona7on.
• Regula,on: Effec7ve regula7on of blood services ensures that they
meet quality and safety standards. Regula7on helps maintain public trust in the blood
dona7on process.
• Na,onal Database: A na7onal database of donors and blood
components can streamline the blood supply chain. It can help iden7fy donor
demographics, rare blood types, and dona7on trends, making it easier to match donors
with recipients.
• Commitment at All Levels: Achieving the goal of 100% self-
sufficiency in blood supply based on VNRD requires commitment at the na7onal,
regional, and local levels. Coopera7on among various stakeholders, including
governments, organiza7ons, and individuals, is vital.
In summary, voluntary blood donors play a pivotal role in promo7ng a culture of VNRD.
Their influence, coupled with support from organiza7ons, financial resources, poli7cal
commitment, educa7on, and effec7ve regula7on, can contribute to a safe and
sustainable blood supply system.