2 .

Ordinary connective tissue

it
CT :

mainly composed of matrix I structure

Collagen
function determined by properties formed from a-chains (20 structure)

of the matrix in triple helix sshapel

arranged

many of which bundle to form

:

connective tissue
fibrils
which are highly organized
in+O ga
I regions
matrix over laD Elastic fibre = elastin fibrillin
in

camorphous ( ( microfibrils)
-= -

- -

ordinary :
specialized
AKA IT ,
.
proper
e in tissues Skin
g such as
e
9
. .

with fibrocytes Cells

Osteocytes then larger) lung
filers bladder
·
(largest)
ligaments
GOVtG
protein
ground substance

(liquid)
Can only stretch to x and

must be mixed with for

overstretch
tissue fluid organic molecules protection against
ER

(cell organelles
Hydrostatic pressure

lowest
proteoglycans glycoproteins forming preprocollagen / collagen precursor) Highest
artery vein lymph
(waterbinding) /protein I
binding) hydroxylation which requires Reason :

Vitamin C High vascular resistance in capillary bed

intO triple helix (snape)

slows blood before it reaches veins

1011agen elastin forming procollagen (collagen precursor) causes of eclema

linelasticl (elastic) 1
.
inflammation/infection causes

yes NO yes NO
flexible ~
vascular permeability
#1 1 Il
e e
I Il Il I .
2
Depleted plasma protein due to
strong
liver/cirrhosis (disease)
registration peptide
function & carboxyl termini 3 due to
collagen shape amino .

High venous pressure

function solubility , prevent aggregation pregnancy
fiberbundle strength bone
1
Removed by procollagen peptidase .
3 Lymphatic obstruction due to

metastasis

elephantiasis (roundworm infection)

fibrils
2 strength + soluble insoluble lymph nocles :
flexible
11 1 and assembles
clear
infect and cancercells
detect and
reticulum scaffold i e liver
3
. .

stroma
If lymph nodes are palpable it's because

they enlarge
(mitosis) infections
during
mest tensile force BM
4 neCk
Numerous in
in all direction
axillat

mediastinum

fibrils anchor mesentery

7
collagens to
groin
BM