Professional Documents
Culture Documents
2018 Cyto
2018 Cyto
Fragments of parenchymal
tissue are seen however there are lot of air drying and crushing artifacts obscuring the detailed
morphology. Focally preserved histiocytic collection is seen.
Smears showing Air Drying and Crushing Artifacts
Specimen: Fluid.
(About 0.5 ml of reddish fluid received)
Clinical Notes: CT scan post craniotomy shows scalp hematoma and persistent lateral and 3rd
ventricle bleed.
Microscopy: The smears are hypocellular with few blood formed elements in thick
protienaceous background.
Clinical Details: Swelling posterior cervical region since childhood. H/O increase in size. No
h/o fever, pain or weightloss. Soft to firm in consistency, measuring 5x4cm.
Microscopy: The smears show many squamous epithelial cells and some keratin flakes.
PAP SMEAR
CYTOLOGICAL FINDINGS
Pap Smear.
(Received 02 unstained smears on glass slides)
None available.
The smear is adequate for reporting.
Junctional zone is represented.
Endocervical epithelial fragments are also present
No epithelial/glandular cell abnormality is seen.
Inflammation is present.
Shift of normal vaginal flora is seen.
No malignant cell is seen
Within Normal Limits
Inflammatory Pattern
Shift of Normal Vaginal Flora
No Malignant Cell Seen
Note : This is a limited opinion due to absence of junctional zone/ endocervical
representation.
Clinical Details: Swelling posterior cervical region since 01yr. H/O increase in size. No h/o
fever, pain. No weightloss. Soft to firm in consistency, measuring 5x4cm. 4.5cc of pus
aspirated.
Microscopy: The smears show sheets of viable and degenerated, necrotic neutrophils.
Microscopy: The smears are hypocellular with blood in thick protienaceous background.
Clinical Notes: Bilateral breast lumps in noticed 5-6yrs back. Mobile nontender, firm and
measure variably from 01 to 02cm. Largest on right medial side was sampled.
Microscopy: The smears are hypocellular. Branched cohesive ductal epithelial fragments are
present in a background of blood with few scattered bare nuclei. No evidence of maliganacy is
seen.
Clinical Details: H/O nodular swellings in left submandibular area, 02x1.5cm, mobile,
nonadherant and tender. Noticed 04yrs ago. H/O fever.
Microscopy: The smears show mostly polymorphous lymphoid cells and tingible body
macrophages. There are lot of crushing artifacts. The background contains blood. No atypical
cells are seen.
The smears show polymorphous lymphoid cells and and neutrophils. There are lot of crushed
epitheloid histiocyte aggregates., vaguely forming granulomata. Focally in the background
necrotic material is identified mixed with blood. No atypical cells are seen.
Note :This lesion is most likely due to Tuberculosis, please correlate clinically and with
relevant laboratory investigations.
Patient’s Name: Muzammal
Age/Sex: 15Y/FM
Lab No : CYTO- 009/18
Date: 09-01-2018
Reference: Dr Zahida Qasim
Clinical Notes: Lump in left breast for 01yr. UOQ , 3.5x04cm, mobile , soft and nonadherant to
surrounding structures.
Microscopy: The smears are hypocellular showing occasional stromal fragments and no ductal
epithelial cells. The background comprises blood. No atypicalcells are seen.
Note : The smears are inadequate for opinion , repeat FNAC/ tissue biopsy is suggested if
clinically indicated.
Clinical Notes: Hard, mobile,1.5cm swelling in right angle of jaw (parotid) for last 01month.
Now increasing in size and no h/o pain on chewing. No h/o fever or weightloss.
Microscopy: The smears are moderately cellular showing cohesive nests of epithelial cells and
numerous chunks of stromal myxoid material. The background contains many myoepithelial
cells.
Microscopy: The smears show sheets of polymorphonuclear leukocytes and few lymphoid
cells clumps. The background comprises necrotic material.
Microscopy: The smears are hypocellular with occasional lymphocyte. The background is
proteinaceous.
Opinion: No Malignant Cell Seen
Note : Please also see histopathology report # S – 031/18 of the same patient.
Clinical Notes: Hard, mobile,1.5cm swelling in left angle of jaw (parotid) for last 4-5yrs, now
increasing in size for last 06months. Increase in size and no h/o pain on chewing with facial
discomfort. No h/o fever or weightloss.
Microscopy: The smears are moderately cellular showing cohesive nests of epithelial cells and
numerous chunks of stromal myxoid material. The background contains many myoepithelial
cells.
Clinical Notes: Left breast lump noticed 01yr back. Mobile nontender, firm and measures
3.5x04cm. Largest on right medial side was sampled.
Microscopy: The smears are hypocellular. Branched cohesive ductal epithelial fragments are
present in a background of blood with few scattered bare nuclei. No evidence of maliganacy is
seen.
Clinical Notes: Right breast lump noticed 02months back. Mobile nontender, soft and
measures 5.5x05cm in UIQ. No h/o fever or cough. Lactating mother.
Microscopy: The smears are moderately cellular. Branched cohesive, monolayered, ductal
epithelial sheets are present in a background of blood withscattered bare nuclei. Stromal
fragments are also seen. No evidence of maliganacy is seen.
Clinical Notes: H/o soft, large lump in right breast in UOQ for last 04months. Nodule measures
5x6.5cm. Right axilla is not involved. No h/o fever, cough, weight loss etc.
Microscopy: The smears are hypercellular showing three dimensional epithelial fragments.
These exhibit dispolarity and hyperchromasia and large atypical nuclei. Atypical epithelial cells
with high N/C ratio are also found in the background of blood.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Details: H/O 03 nodular swellings in left supraclavicular area, mobile, nonadherant and
tender. Noticed 01month ago.No H/O fever.
Microscopy: The smears show mostly polymorphous lymphoid cells. There are lot of crushing
artifacts. The background contains blood and few adipose tissue fragments. No atypical cells or
granulomata are seen.
Clinical Notes: Solitary thyroid nodule in right lobe for last 01yr. Feels dyspnoic but no
associated toxic symptoms. Cold nodule on scan.
The smears are moderately cellular. Sheets of follicular cells are present.Few hemosiderin laden
macrophages are also seen in the background of blood mixed with thin colloid.
Suggestive of Adenomatous Colloid Nodule
Bethesda Reporting Category II (Benign)
Clinical Notes: Swelling infront of neck, 6x3cm, since birth? Now increasing in size. Moves
with swallowing.
Microscopy: The smears comprise blood only. No follicular or any other epithelial cells are
seen.
PAP SMEAR
CYTOLOGICAL FINDINGS
Microscopy: The smears show blood with polymorphonuclear leukocytes and few lymphoid
cells clumps. No LD bodies are seen. The background comprises blood.
Clinical Details: Swelling on anterior chest wall since 01yr. H/O increase in size for last 01wk
after scratching. No h/o fever, weightloss. Firm, red and inflamed measuring 2.5cm. Pus
aspirated. Inflamed Sebaceous cyst?
Microscopy: The smears show sheets of viable and degenerated neutrophils. There are
admixed many mature squames.
Clinical Notes: Swelling in left thigh, progressively increasing in size. Fluid? sampled.
Microscopy:The smear is moderately cellular with cohesive tiny fragments of mature looking
adipose tissue. The background contains lipoid droplets.
Microscopy: The smears are comprise blood and its formed elements. No atypical cell is seen.
Microscopy: The smears are hypocellular showing mostly blood formed elements. No
epithelial/lymphoid cells are seen.
Opinion: Hemorrhagic Aspirate ----- Site NOS
Inadequate for Reporting
PAP SMEAR
CYTOLOGICAL FINDINGS
Microscopy: The smears are moderately cellular with inflammatory cells and mesothelial cells
showing reactive changes. The background is clear.
Microscopy: The smears are hypercellular with mostly lymphocytes and RBC. Mature and
larger forms of the former are seen in the protienaceous background.
Opinion: Lymphocytosis
Suspicious for Atypia
Note : Please correlate with clinical findings. Immunohistochemistry can be done on cell
block for definite diagnosis, if requested separately. and with site of aspiration.
Clinical Notes: Breast lump in ILQ on rightside, noticed 08months back. Mobile nontender,
firm and measures 02cm.
Microscopy: The smears are hypercellular. Branched cohesive ductal epithelial fragments are
present in a background of blood with many scattered bare nuclei. No evidence of malignacy is
seen.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Notes: Multinodular thyroid in right & left lobes for last 06yr. No associated toxic
symptoms. Measures 3x4cm.
Microscopy: The smears are moderately cellular. Tight clusters of follicular cells are
present.Few hemosiderin laden macrophages are also seen in the background of blood mixed
with thin colloid.
PAP SMEAR
CYTOLOGICAL FINDINGS
Microscopy: The smears are moderately cellular showing mature squames and
polymorphonuclear cells. Mucoid material is present in the back ground. No atypical cell is
seen.
PAP SMEAR
CYTOLOGICAL FINDINGS
PAP SMEAR
CYTOLOGICAL FINDINGS
Microscopy: The smears are hypocellular with few lymphocyte. Occasional mesothelial cell is
seen in clear background.
Microscopy: The smears are moderately cellular. The background of blood shows quite afew
cells with drying artifacts. Morphology is not discernible
Note : The smears are inappropriate for reporting, repeat FNAC is suggested. Please
immerse slides in absolute alcohol immediately after preparation for better preservation.
Please also provide complete clinical information for better interpretation.
Note : The smears are inappropriate for reporting, repeat test is suggested. Please add
absolute alcohol immediately after retrieval of specimen for better preservation. Please also
provide complete clinical information for better interpretation.
Pap Smear.(Liquid based cytology
(Received 05ml fluid with LBC brush)
Prepared x02 smears.
Patient’s Name: Asia
Age/Sex: 38Y/FM
Lab No : CYTO – 039/18
Date: 21-02-2018
Reference: Medpath Lab
Clinical Details: Swelling left arm since 01month. H/O increase in size and pain. No h/o fever,
or weightloss. History of I/m injection 3-4months earlier. OE; Soft to firm in consistency,
measuring 10x08cm. Pus aspirated in needle butt.
Microscopy: The smears show sheets of viable, degenerated and necrotic neutrophils.
Note : Please correlate with clinical findings and microbial culture findings.
Clinical Details: Right breast tender nodule (1.2cm) involving the OUQ, noticed on USG. H/O
pain esp. premenstrual for last 02year. No h/o increase in size, fever or weight loss. No Family
history of breast pathology.
Microscopy : The smears are hypocellular with few small,cohesive fragments of ductal
epithelium seen along with some adipose tissue fragments. Atypia, mitoses or necrosis are not
identified. The background shows blood.
Clinical Notes: Recurrentlump in left breast last year. Now for last 15days in UOQ, 2.5cm,
mobile , tender and nonadherant to surrounding structures.
Microscopy: The smears are hypocellular showing occasional histiocyte and no ductal epithelial
cells. The background comprises blood. No atypical cells are seen.
Note : The smears are inadequate for opinion , tissue biopsy is suggested if clinically
suspicious.
Clinical Notes: H/O right breast lump noticed 2-3months back. Mobile,tender, firm and square
in shape? measures 3.5x04cm in UOQ.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with few scattered bare nuclei. No evidence of malignancy
is seen.
Clinical Details: Left breast nontender nodule (2x2cm) involving the IUQ, noticed 12year ago.
Now increasing in size, No h/o fever or weight loss. Now getting checked due to cancer
awareness program. Breastfed 03 children, LCB 3yr. Four ml of yellowish milky fluid aspirated
and lump reduced in size.
Microscopy : The smears are moderately cellular with numerous foamy histiocytes in a
protienaceous background. The latter contains few inflammatory cells too. No ductal cells are
identified. Atypia, mitoses or necrosis are not seen.
Microscopy: The smears are hypocellular showing blood formed elements only. No follicular /
epithelial/lymphoid or any other parenchymal cells are seen.
Note : Repeat FNAC is suggested. This Please provide complete clinical information .
Clinical Details: H/O right parotid swelling for last 03weeks. Following h/o fever, No h/o or
weight loss. Large 5x6cm, hard swelling.
Microscopy: The smears are moderately cellular. Cohesive sheets of ductal epithelium are
present in monolayers. The background comprises blood with occasional stromal fragment.
Many epitheloid histiocyte collections / granulomata are seen.
Note : This may represent Viral infection, however necrotizing sialmetalpasia cannot be
ruledout. Please correlate with relevant laboratory and clinical findings.
PAP SMEAR
CYTOLOGICAL FINDINGS
Note Opinion is limited due to air drying effects and absence of junctional zone
representation.
Microscopy: The smears are hypercellular with sheets of atypical large lymphoid cells mixed
with neutrophils.
Microscopy: The smears are acellular . Amorphous material is seen in clear background.
Note : The aspirate is autolysed. Please preserve sample in alcohol/formalin for better
interpretation.
Clinical Notes: Multiple thyroid nodules for last 09yr. Feels few associated toxic symptoms.
Microscopy: The smears are moderately cellular. Sheets of follicular cells are present.
Numerous hemosiderin laden macrophages are also seen in the background of blood mixed with
thin colloid.
Clinical Details: H/O left cervical lymphadenopathy (7x8cm) for 2wks, progressively increasing
in size. H/O low grade fever. No family hx of TB.
Microscopy: The smears show monomorphous population of lymphoid cells many showing
crushing as well. There are few larger cells also presesnt. In the background blood is present.
Notes : Excision biopsy with immunohistochemistry is suggested for tissue diagnosis and
further categorization.
Clinical Notes: Left breast lump noticed 8-10yr back. Mobile nontender, firm and measures
05x06cm. No h/o fever, weight loss or family h/o Ca breast.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with few scattered bare nuclei. No evidence of maliganacy
is seen.
Clinical Notes: Breast lump in UIQ of right breast, noticed 02months back. Associated with
pain. Measures 3x3cm.
Microscopy: The smears are hypocellular. Monolayered, cohesive ductal epithelial fragments
are present in a background of blood with few scattered cells with larger nuclei..
Note : In the light of age and clinical information of paeu de orange, this aspirate may not
be a true representative of the lesion. Trucut biopsy / US guided FNAC is suggested.
Microscopy: The smears are hypercellular with many mature neutrophils. Occasional
lymphocyte and mesothelial cells are seen in the background.
PAP SMEAR
CYTOLOGICAL FINDINGS
Source of specimen: Pap Smear.
(Received 04x unstained slide)
Specimen: Fluid.
(About 10ml of straw colored fluid received)
The smears are hypercellular with many mature neutrophils. Occasional lymphocyte and
mesothelial cells are seen in the background.
Clinical Notes: Right breast lump noticed 3-4yr back in UOQ. Mobile nontender, firm and
measures 05x05cm. Lipoma is present in right shoulder aswell.
Microscopy: The smear is hypocellular with cohesive tiny to medium sized fragments of mature
looking adipose tissue. The background contains lipoid droplets.
Clinical Notes: Left breast lump noticed 04months back. Mobile,nontender, hard and measures
05x05cm. Axillary nodes palpable. USG; BIRAD IV. Family h/o Ca breast .
Microscopy: The smears are hypercellular showing three dimensional, partly dyshesive
epithelial fragments. These exhibit dispolarity and nuclear hyperchromasia . Atypical epithelial
cells with high N/C ratio and eccentric nuclei are found in the background.
Clinical Details: Swelling back of chest, left side. H/O increase in size. No h/o fever, pain or
weightloss. Scanty white material obtained with foul smell.
Microscopy: The smears are hypocellular and show keratin flakes and few anuclear squames.
The background is clear.
Note : This may represent epidermal inclusion cyst, please correlate with clinical findings.
Adenomyoepithelioma
Patient’s Name: Mehboob Hussain
Age/Sex: 48Y/M
Lab No : CYTO -059/18
Date: 12-03-2018
Reference: Ultra Lab
Clinical Notes: Swelling infront of neck, for last 2.5 years. USG shows multinodular goiter with
prominent left lobe.
Microscopy: The smears comprise only scanty blood. No follicular or any other epithelial cells
are seen.
Note : The smears are inadequate for opinion , repeat FNAC is suggested if clinically
indicated.
Microscopy: The smears are hypocellular with mostly blood and occasional clump of
lymphocyte.
Clinical Notes: Left breast lumpin UIQ,noticed 01yr back. Mobile nontender, firm and
measures 2.5x03cm. Nonlactating mother, LCB 05months.
Microscopy: The smears are moderatel cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with few scattered bare nuclei. No evidence of malignancy
is seen.
Clinical Notes: Multinodular thyroid, more so in left lobe for last 2-3yr. H/O associated toxic
symptoms for which already taking neomercazole and inderal.Now has no signs of toxicity and
TFT are WNL. Blood stained fluid 12 ml aspirated.
Microscopy: The smears are hypocellular. Occasional tiny clumps of follicular cells are
present.Few hemosiderin laden macrophages are also seen in the background of blood mixed
with thin colloid.
Microscopy: The smears are moderately cellular with lymphocyte and few RBCs. Occasional
columnar epithelial cells are seen. However the smear shows degenerative effects.
Clinical Notes: Right breast lump noticed 2-3months back in OUQ. Mobile nontender, firm
and measures 3.5x05cm. Nonadherent to underlying structures.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with few scattered bare nuclei. No evidence of maliganacy
is seen.
Microscopy: The smears are hypercellular. There are many small clumps of atypical cells with
hyperchromatic nuclei and irregular nuclear contours. The background comprises blood,
inflammatory cells, reactive mesothelial cells and protienaceous background.
Specimen: CSF.
(About 2.5 ml of clear fluid received)
Microscopy: The smears are cellular with few mature lymphocyte and neutrophils.
PAP SMEAR
CYTOLOGICAL FINDINGS
CYTOLOGICAL FINDINGS
Clinical Details: H/O left submandibular swelling for last 02months. No H/O weight loss or
fever. Size 2.5-03cm. mobile, nontender, nonadherant.
The smears show polymorphous lymphoid cells. Many epitheloid histiocyte collections are
present in the background composed of blood containing numerous neutrophils.
Microscopy: The smears are hypocellular with few lymphocytes and neutrophils. Occasional
mesothelial cell is seen in a clear background.
Microscopy: The smears show sheets of viable and degenerated, necrotic neutrophils. The
background shows phagocytic histiocytes .
Clinical Notes: Right breast lump for last 1year. Size 13x10cm, mobile nontender, firm nodule.
H/o low grade fever and weight loss.
Microscopy: The smears are moderately cellular. branched and unbranched cohesive and partly
dyshesive ductal epithelial, three dimensional fragments are present in a background of
proteinaceous material with scattered histiocytes.
Microscopy: The smears show few inflammatory cells, along with few epithelial cells.
PAP SMEAR
CYTOLOGICAL FINDINGS
Microscopy: The smears are hypocellular with few lymphocyte. Occasional mesothelial cell is
seen in clear background.
PAP SMEAR
CYTOLOGICAL FINDINGS
Note : This is a limited sample, please correlate with clinical findings. Please send smear
covering atleast 10% of the slide surface area, well preserved in absolute alcohol
immediately after preperation.
Report by Dr Asna Haroon Khan
(Al Rehman Medical Laboratory)
Microscopy: The smears are hypocellular with mostly RBC and occasional lymphocyte. The
background is dense.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Notes: Lump in left breast for 01yr.Tender, mobile, multiple nodules, nonadherant to
surrounding structures.
Microscopy: The smears are hypocellular showing scanty blood only and no ductal epithelial
cells. No atypicalcells are seen.
Note : The smears are inadequate for opinion , repeat FNAC/ tissue biopsy is suggested if
clinically indicated. Please note that left or right was not marked on the slides.
Specimen:
Clinical Notes: Swelling on right shoulder posteriorly, for last 2-3years. Now neck stiffness is
experienced..
Microscopy:The smears are hypocellular with cohesive tiny fragments of mature looking
adipose tissue. The background contains lipoid droplets.
Microscopy: The smears are hypercellular with many mature neutrophils. Occasional
lymphocyte and mesothelial cells are seen in the background.
Clinical Notes: Breast lump at the base of left areola with nipple retraction noticed 20 days
back. Size 3x3cm, painful.
Microscopy: The smears are moderately cellular with sheets of degenerated neutrophils ,
phagocytic histiocytes, giant cells and many granulomata. Afew normal looking ductal epithelial
fragments are also present. No evidence of maliganacy is seen.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Details: Copious PV discharge and PC bleeding. OE: Cervical ectropion, hypertrophy
and curdy discharge.
Microscopy: The smear is adequate for reporting.
Junctional zone is represented.
Endocervical epithelial fragments are not present.
No epithelial/glandular cell abnormality is seen.
Mild Inflammation is seen.
No malignant cell is seen.
Clinical Notes:Nodule in right lobe for last few years. No H/O associated toxic symptoms .
Rapidly increased in size over last 06wks. Size 08x05cm. Brown colloidal fluid, 30 ml,
aspirated.
Microscopy: The smears are hypocellular. Many hemosiderin laden macrophages are seen in the
background of thick colloid. Follicular cells are not seen.
Clinical Details: H/O left preauricular swelling for last 02years. No H/O weight loss or fever.
Size 2.5cm. mobile, nontender, nonadherant.
Microscopy: The smears show polymorphous lymphoid cells. Many epitheloid histiocyte
collections are present in the background composed of blood containing lymphoid cells.
Note : The lesion may be due to tuberculosis, please correlate with clinical and relevant
investigations.
Clinical Notes: Left breast lump noticed 02years back. Mobile,discoid, nontender, hard and
measures 05x05cm in OUQ. Ipsilateral axillary node is palpable. Previously done FNAC of LN
was reported benign. No Family h/o Ca breast .
Microscopy: The smears are hypercellular showing three dimensional, dyshesive epithelial
fragments. These exhibit dispolarity and nuclear pleomorphism. Atypical epithelial cells with
high N/C ratio are found in the background.
Microscopy: The smears are hypocellular with few inflammatory cells and mesothelial cells.
The background is protienaceous.
Clinical Notes: Right breast lump noticed 03months back. Mobile nontender, firm and
measures upto 01cm in IUQ. H/O pregnancy of about 07wks duration.
Microscopy: The smears are hypocellular. Small tight cohesive ductal epithelial fragments are
present in a background of blood with few scattered bare nuclei. No evidence of maliganacy is
seen.
Clinical Details: H/O right cervical nodule (2x3cm) of long standing, progressively increasing in
size. Also noticed increase in size during URTI. No H/O low grade fever. No family hx of TB.
Clinical Notes: Right cervical Lump for last 1.5month, measuring 4x2cm. Also h/opain and
dysphagia/odynophagia with weight loss.
Microscopy: The smears are moderately cellular. Clusters of atypical cells are seen
intermingled with lymphocyte and neutrophils. Blood and necrotic tissue with scattered atypical
cells is forming the background .
Microscopy: The smears show many viable and degenerated, necrotic neutrophils. Amongst
these few macrophages with phagocytosed material are also seen. Lymphocytes are also present.
Clinical Notes: Multinodular thyroid for last 20yr. Gradually increasing in size Now feels
dyspnoic but no associated toxic symptoms.
Microscopy: The smears are moderately cellular. Monolayeredsheets of follicular cells are
present.Few hemosiderin laden macrophages are also seen in the background of blood mixed
with colloid.
Opinion: Adenomatous Colloid Nodule ----- Thyroid
Bethesda reporting Category II (Benign)
Clinical Notes: Left breast lump for last 06months. Size 29.9x24.3x26.3cm, mobile nontender,
firm nodule. H/o pain for last 01month. H/O paternal aunt being diagnosed for CA breast.
Microscopy: The smears are hypocellular. Few groups of partly dyshesive ductal epithelial cell
are seen, these show air drying effects. Few normal looking epithelial fragments are also seen.
Naked , air dried nuclei are present in a background of blood.
Clinical Details: Swelling posterior cervical region since 02months. H/O increase in size. There
is h/o fever, pain. No weightloss. Soft to firm in consistency, measuring 5x4cm. One cc of pus
aspirated.
Microscopy: The smears show sheets of viable and degenerated, necrotic neutrophils.
Clinical Notes: Enlarged thyroid in right & left lobes for last 12yrwith a nodule on right side.
No associated toxic symptoms. Measures 3x4cm and gives pressure symptoms.
Microscopy: The smears are hypocellular. Few clusters of follicular cells are present in the
background of blood mixed with thick colloid.
Clinical Notes: Multinodular thyroid around the neck for last 20yr. No associated toxic
symptoms. Measures 10x12cm and associated with difficulty in breathing.
Microscopy: The smears are moderately cellular. Tight clusters and monolayered sheets of
follicular cells are present.Few hemosiderin laden macrophages are also seen in the background
of blood mixed with thin colloid.
Microscopy: The smears are hypocellular with few lymphocyte. Occasional mesothelial cell is
seen in clear background.
Clinical Details: H/O rightParotid nodule for last 01month. No H/O weight loss. H/O
pain and fever. Size 1.5-1.5cm. Fixed.
Note : The lesion may be due to tuberculosis, please correlate with clinical and
relevant investigations.
Clinical Notes: Painless swelling infront of neck, for last 2 years. Size : 3.5x2.8cm.
Microscopy: The smears comprise only scanty blood. No follicular or any other epithelial cells
are seen.
Note : The smears are inadequate for opinion , repeat FNAC is suggested if clinically
indicated.
Microscopy: The smears are moderately cellular with white blood mostly lymphocytes and few
neutrophils in a clear background.
Microscopy: The smears are hypocellular. Few clumps of follicular cells are present. The
background of blood is mixed with thin colloid.
Clinical Details: H/O left cervical lymphadenopathy 1.5cm for 201wk, progressively increasing
in size. H/O RHC pain and cough for last 3-4days. Noh/o fever or rash. Strong family Hx of TB.
Microscopy: The smears are moderately cellular showing cohesive nests of epithelial cells and
few chunks of stromal tissue are also seen. The background contains many epithelial cells and
blood.
Note : The differential also includes Mixed Salivary Gland Tumor. Excision is required for
definite tissue diagnosis.
Microscopy: The smears are hypocellular with few degenerated cells only. The background is
amorphous.
Opinion: No Malignant Cell Seen
Microscopy: The smears are hypocellular with few lymphocyte. Occasional mesothelial cell is
seen in clear background.
Clinical Details: H/O bilateral neck swellings for last 06months. H/O weight loss, but no
fever. Discrete, variably sized, mobile, nontender, nonadherant, bilateral nodes. Both
sides sampled.
Note : The lesion may be due to tuberculosis, please correlate with clinical and
relevant investigations.
Microscopy: The smears are hypocellular showing occasional squamous cell and no ductal
epithelial cells. The background is clear.
Note : The smears are inadequate for opinion , tissue biopsy is suggested if clinically
indicated.
Clinical Notes: Left breast lump noticed 01yr back. Mobile,tender, hard and measures
03x05cm, below the nipple. Axillary lump was exiced 15days ago and reported to be invasive
breast carcinoma.
Microscopy: The smears are hypocellular showing tiny, dyshesive epithelial clusters. These
exhibit nuclear hyperchromasia and pleomorphism . Afew such cells are also found in the
hemorrhagic background.
Clinical Notes: Thyroid enlarged for last 03yr. No definite associated toxic symptoms, though
she has anxiety. USG and scan not done yet. Has been taking intermittent treatment for toxic
symptoms.
Microscopy: The smears are hypocellular. Few clumps of follicular cells are present embedded
in colloid. Many hemosiderin laden macrophages are also seen in the background of blood mixed
with thin colloid.
Clinical Details: Swelling right jaw region since 02yr. H/O vexing and vanning in size. No h/o
fever, pain. No h/o weightloss. Firm in consistency, measuring 3x2cm. skin reddened and
pointing seen. Pus aspirated.
Microscopy: The smears show sheets of viable and degenerated, necrotic neutrophils.
Occasionally the background shows mature squamous epithelial cells.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Notes: H/o soft, lump in right breast in LOQ for last 02months. Nodule measures
2x2cm. skin is tethered. Nipple is normal looking. No h/o fever, cough, weight loss etc.
Microscopy: The smears are hypercellular showing dyshesive, epithelial fragments. These
exhibit dispolarity and hyperchromasia and large atypical nuclei. Atypical epithelial cells with
high N/C ratio are also found in the background of blood.
Clinical Details: Lump left breast since 05days. No h/o fever, pain or weightloss. Soft to firm in
consistency, measuring 3x3cm. Pus aspirated.
Microscopy: The smears show sheets of viable and degenerated, necrotic neutrophils. Few
plump epithelial cells are also seen.
Clinical Details: Swelling left side of neck for 1.5months. H/O dyspnea and dysphagia. Size is
2x2cm. No other lymphadenopathy.
Microscopy: The smears show sheets of squamous cells, few show individual cell
keratinization. Viable and degenerated neutrophilsare also seen.
Note : Keeping in view the clinical history and age of the patient, primary in upper
aerodigestive tract may please be ruledout.
Clinical Details: EUS done. Periampullary growth leading to obstructive jaundice, Findings;
heterogenous mass around distal end of CBD measuring 2.5x1.5cm. ROSE shows scanty
malignant cells.
Microscopy: The smears comprise blood. Occasional atypical epithelial cells are seen.
Note : Please also see histopathology report # S- 654-2018 of the same patient.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Details: H/O thyroid swelling (2x3cm) for last 06months. Firm, mobile and
progressively increasing in size. No H/O associated symptoms.
Microscopy: The smears show polymorphous population of lymphoid cells showing extensive
air drying and crushing artifacts. There are few large cells also present. Afew clusters of
polygonal cells are also identified. In the background blood formed elements including
eosinophils are present.
Notes : Repeat FNAC with appropriate fixation/ tissue biopsy is suggested for definite
diagnosis.
Report by Dr Asna Haroon Khan
(Al Rehman Medical Laboratory)
Clinical Details: H/O central thyroid swelling (2x3cm) for last 06months. Firm, mobile and
progressively increasing in size. Small supraclavicular nodule is also palpable. No H/O
associated symptoms.
Microscopy: The smears show atypical cells with extensive streaking affect. There are few
large cells also presentwith ample eosinophilic cytoplasm. Afew singly scattered large cells with
hyperchromatic nuclei are also identified. The background contains necrotic material ,blood
formed elements including eosinophils.
Notes : Opinion is limited due to exrensive crushing. Differential include high grade
thyroid carcinoma. Please correlate with imaging findings.
Specimen: CSF.
(About 1.5 ml of clear fluid received)
Microscopy: The smears are cellular with few mature lymphocyte and red blood cells.
Clinical Notes: Swelling forehead, 2x2cm, for last 05yr. No h/o fever, pain, weight loss or any
other active complaint. OE : overlying skin is normal.
DDx: cyst/ lipoma.
Microscopy: The smears comprisescanty blood only. No adipocytes or any other epithelial cells
are seen.
Note : The smears are inadequate for opinion , repeat FNAC/ excision is suggested if
clinically indicated.
Clinical Notes: H/o hard, mobile, nontender, lump in right breast in UIQ for last 3-4months.
Nodule measures 8x6cm. History of goiter for last 07 years aswell.
Note : Morphology is suggestive of a high grade neoplasm. Biopsy is suggested for definite
tissue diagnosis.
Clinical Details: Lump in OUQ of left breast since 05days. No available h/o fever, pain or
weightloss. Firm in consistency, measuring 3x3cm. No FHx of Ca breast.
Microscopy: The smears show sheets of viable and degenerated, necrotic neutrophils.
Occasional cluster of plump epithelial cells is also seen.
Clinical Notes: Thyroid nodule in left lobe for last 01month. Feels dysphagia but cleared by
ENT. No associated toxic symptoms. Multiple calcific nodules on USG. OE; Multinodular more
on left. 12cc thick colloid aspirated.
Microscopy: The smears are hypocellularwith mostly acute inflammatory cells. No follicular
cells are present however few large bizarre looking hyperchromatic cells are seen with large
nuclei.Few hemosiderin laden macrophages , microcalcification and occasional multinucleated
giant cells are also seen in the background of thick colloid.
Note : Considering the age of the patient and history of rapid growth , excision is suggested
for definite diagnosis.
Reported by Dr Asna Haroon Khan
(Al Rehman Medical Laboratory)
Clinical Notes: Solitary thyroid nodule in right lobe for last 01yr. Feels dyspnoic but no
associated toxic symptoms. Cold nodule on scan.
Microscopy: The smears are moderately cellular. Sheets of follicular cells are present.Few
hemosiderin laden macrophages are also seen in the background of blood mixed with thin
colloid.
Clinical Notes: Breast lump above the left areola noticed 30 days back. The nipple is retracted
on this side since childhood and has not breast fed children from this side. OE; size 5x3cm,
slightly painful firm with tethering of skin. No FHx of breast pathology. Last child born is 3yrs.
Microscopy: The smears are moderately cellular with sheets of neutrophils and few
lymphocytes. Many phagocytic histiocytes, multinucleate giant cells and epitheloid cell
granulomata are present. Afew normal looking ductal epithelial fragments are also present. No
evidence of malignacy is seen.
Clinical Notes: Diffuse thyroid swelling since childhood. H/O generalized weakness with it.
Microscopy: The smears are hypocellular. Clusters of follicular cells are present.Few
macrophages are also seen in the background of blood mixed with thin colloid.
Clinical Notes: Solitary thyroid nodule(02cm) in isthmus of thyroid for last 03yr. Feels
dyspnoeic but no associated toxic symptoms.
Microscopy: The smears are moderately cellular. Sheets of follicular cells and macrofollicles are
present. Clusters of hemosiderin laden macrophages are also seen in the background of blood
mixed with thick colloid.
Microscopy: The smears show occasional inflammatory cells. No epithelial cell is identified.
The background is proteinaceous and contains few RBC.
Note : Cystic mucoepidermoid carcinoma cannot be ruled out, please correlate with clinical
findings. Excision biopsy is suggested for definite tissue diagnosis.
Microscopy: The smears comprise blood. Afew epithelial cells are seen. No overt atypia is seen.
Note : Please also see histopathology report # S- 752-2018 of the same patient.
Reported by Dr Asna Haroon Khan
(Al Rehman Medical Laboratory)
Clinical Notes: Suspicious of intestinal TB. Multiseptate fluid. Diagnostic tap done.
Microscopy: The smears are hypocellular with few lymphocyte and occasional mesothelial cell
is seen in a proteinaceous thick background.
Clinical Notes: A thyroid nodule(4x3cm) in center for last 10yr. Now c/o sore throat often but
no associated toxic symptoms.
Microscopy: The smears are moderately cellular. Clusters of follicular cells are present. Sheets
of epitheloid histiocytes are also present. Few hemosiderin laden macrophages are also seen in
the background of blood mixed with colloid.
Clinical Notes: Thyroid nodule(2x2cm) in isthmus for last 04months. H/O toxic symptoms like
fine tremors and associated weightloss and weakness.USG showed a nodule(1.2x0.8cm)with
cystic component.
Microscopy: The smears are moderately cellular. Macrofollicles of follicular cells are
present.Few hemosiderin laden macrophages are also seen in the background of blood mixed
with thick colloid.
Microscopy: The smears are moderately cellular with blood formed elements and mesothelial
cells. Afew large cells with vacuolated cytoplasm and hyperchromatic nuclei are also seen.The
background is thick and protienaceous.
Clinical Notes: Left breast lump in UOQnoticed 01month back. Mobile nontender, firm and
measures 3.5cm. No palpable axillary nodes. Associated myalgias and joint pains.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with few scattered bare nuclei. Stromal fragments are also
seen. No evidence of malignancy is seen.
Note : Keeping in view the age of the patient, regular followup is suggested and excision
biopsy is recommended if clinically suspicious.
Clinical Details: H/O nodular swellings in left postauricular area, 02x1.5cm, mobile,
nonadherant and tender. Noticed 02months ago. One sebaceous cyst in scalp. No associated
symptoms.
Microscopy: The smears show mostly polymorphous lymphoid cells and tingible body
macrophages. There are lot of crushing artifacts. The background contains blood. No atypical
cells are seen.
Clinical Details: Left breast, nontender lump involving the lateral side noticed 02 months ago.
Now increasing in size, No h/o fever or weight loss. Yellowish milky fluid aspirated and similar
nipple discharge.
Microscopy : The smears are hypocellular with occasiona smallductal and stromal fragments.
Occasional foamy histiocyte is also seen in the clear background. Atypia, mitoses or necrosis are
not seen.
PAP SMEAR
CYTOLOGICAL FINDINGS
None available.
Microscopy: The smears are hypocellular with few neutrophils and lymphocyte. Occasional
mesothelial cell is seen in clear background.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Details: Lump left breast since 07days. No h/o fever, pain or weightloss. Soft to firm in
consistency, measuring 02cm. Lactating LCB 01yr. Milky fluid aspirated.
Microscopy: The smears show clusters of viable and degenerated neutrophils. Few fragments
of adipose tissue are also seen. The background contains foamy histiocytes and inspissated
secretions.
Clinical Notes: Solitary thyroid nodule in center of neck for last 25yr. Now feels dyspnoeic but
no associated toxic symptoms. Cold nodule on scan. She has sporadically been taking
Neomercazole. TFT are WNL. HCV+ and has taken Tx once, now PCR positive again.
Microscopy: The smears are moderately cellular. Three dimensional sheets of follicular cells
are present, these show oblong nuclei and occasional grooves.Nuclear overlapping is also seen.
Similar cells are also seen in the background of blood mixed with scanty thick colloid.
Clinical Notes: Left breast lump, UIQ,noticed 01wk back. Mobile nontender, firm and
measures 1.5cm.
Microscopy: The smears are hypercellular. Branched cohesive ductal epithelial fragments are
present in a background of blood with many scattered bare nuclei. Cellular stromal fragments are
also seen. No evidence of maliganacy is seen.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Notes: USG: Swelling left angle of mandible, 54.8x42.9x61.7mm. Cystic and
peripheral echogenic texture. Complex parotid mass with prominent posterior group enlarged
LN, largest 22mm.
Microscopy: The smears comprise blood only. No epithelial or other cells are seen.
Note : The smears are inadequate for opinion , repeat FNAC is suggested.
Clinical Notes: Recurrent ovarian cyst. Lap findings : Large left ovarian cyst, adherent to
adjacent structures, found on laparotomy, marsupulization done.
Microscopy: The smears are hypocellular with few blood formed elements in a clear
background.
Clinical Notes: Diffuse thyroid swelling for last 04months. No associated toxic symptoms.
Subcentimeter nodules on USG. No nodules visible on clinical examination. Random FNAC
done.(Declined US guided FNAC)
Microscopy: The smears are moderately cellular. Macro and microfollicles of normal looking
cells are present.Few hemosiderin laden macrophages are also seen in the background of blood
mixed with thin colloid.
Specimen: Fluid.
(About 0.5 ml of reddish fluid received)
Microscopy: The smears are moderately cellular with inflammatory cells , mostly lymphocytes
and other blood formed elements in thick background containing microbial colonies.
Microscopy: The smears are hypocellular with few lymphocyte. Rare mesothelial cell is seen
in clear background.
Microscopy: The smears show sheets of viable and degenerated, necrotic neutrophils.
Microscopy: The smears are hypercellular with mostly lymphocytes and occasional neutrophil
and RBC. Mature and larger forms of the lymphocytes are seen in a clear background.
Opinion: Lymphocytosis
Note : Please correlate with clinical findings.
Clinical Details: Left breast nontender nodule (4x3cm) involving the UOQ, noticed 10days ago.
Now increasing in size, No h/o fever or weight loss. No associated skin or nipple
changes.Breastfeeding. Milky fluid aspirated.
Microscopy : The smears are hypocellular showing foamy histiocytes in a clear background.
The latter contains few inflammatory cells too. No ductal cells are identified. Atypia, mitoses or
necrosis are not seen.
Clinical Notes: Multinodular thyroid for last 20yr. No associated toxic symptoms. Measures
10x12cm.
Microscopy: The smears are hypocellular. Few clusters of follicular cells are present and few
hemosiderin laden macrophages are also seen in the background of blood. Few clusters show
oblong nuclei with cleaves and occasion inclusion like morphology. Few large nuclei are also
seen.
Note : Few clusters are suspicious for features of papillary carcinoma thyroid. However
fixation artifacts are also present. Excision is suggested for definite diagnosis.
Microscopy: The smears comprise blood and its formed elements. Few mesothelial cells are
also present. No atypical cell is seen.
Microscopy: The smears are hypercellular with lymphocyte and occasional mesothelial cell in
clear background. There are groups of large atypical cells seen with pleomorphic nuclei.
Clinical Details: Swelling right submandibular region for 04yr. H/O increase in size. No h/o
fever, pain or weightloss. Soft to firm in consistency, measuring 3x3cm. Overlying skin is
normal.
Microscopy: The smears are hypocellular showing blood formed elements only including
neutrophils.
Note : Please correlate with clinical findings. Repeat FNAC or biopsy may be considered
in case of high clinical suspicion.
Microscopy:The smear are hypocellular with few tiny cohesive fragments of mature looking
adipose tissue. The background contains lipoid droplets and few lymphocytes.
Clinical Notes: Multinodular thyroid with a dominant nodule in right lobe for last several years.
Now feels dyspnoeic and obstructive symptoms but no associated toxicity. TFTs are WNL. Scan
not available.
Microscopy: The smears are hypocellular. Tiny clusters of follicular cells are present.
Numerous hemosiderin laden macrophages are also seen in the background of blood mixed with
thin colloid.
Opinion: Suggestive of Adenomatous Colloid Nodule ----- Thyroid
Bethesda reporting Category II (Benign)
Clinical Details: H/O nodular swellings in left axilla, 1.5cm, mobile, nonadherant and slightly
tender. Noticed 10months ago after an episode of breast abscess during lactation.
Microscopy: The smears show mostly polymorphous lymphoid cells and tingible body
macrophages. There are lot of crushing artifacts. The background contains blood. No atypical
cells are seen.
Clinical Notes: Bilateral breast lumps in noticed 03months back. Mobile nontender, firm and
measure variably from 01 to 03cm. Largest subareolar (03cm)on right side was sampled.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with few scattered bare nuclei. No evidence of maliganacy
is seen.
Clinical Notes: Right hand nodule on lateral aspect,noticed 02months back. Measures01x1.5cm.
No h/o fever.
Microscopy: The smears are hypocellular. Few cohesive epithelial fragments are present in a
background of blood with few scattered multinucleate giant cells. No evidence of malignancy is
seen.
Note : The morphology is most suggestive of benign skin adnexal tumor/cyst, however
differential also includes Giant cell tumor of tendon sheath. Please correlate.
Clinical Details: Obstructive jaundice due to Ca head of pancreas. ROSE: showed malignant
cells likely Ca.
Note : Please also see histopathology report # S- 923-2018 of the same patient.
Microscopy: The smears are hypercellular with mostly lymphocytes and RBC. Mature and
larger forms of the former are seen in the protienaceous background.
Opinion: Lymphocytosis
Suspicious for Atypia
Clinical Notes: Lipomatous , soft nontender lump , 3x3cm. Left side of back.
Microscopy: The smears are hypocellular showing occasional fibrous stromal fragments and
blood formed elements only. No parenchymal cells or adipocytes are seen.
Microscopy: The smears are hypercellular with many cells containing vesicular and
occasionally cleaved nuclei. The background contains lymphocytes and neutrophils.
Note : Reactive mesothelial atypia cannot be ruledout. Opinion is limited by lack of clinical
information, please correlate.
Reported by Dr Asna Haroon Khan
(Al Rehman Medical Laboratory)
Microscopy: The smears are hypercellular with blood formed elements in thick protienaceous
background.
Note : Please correlate with clinical findings. Please also see report #
S- 941/2018 of the same patient.
Clinical Details: H/O nodular swelling in left axilla, 03x3.5cm, mobile, nonadherant and
nontender. Noticed 02months ago. H/O Birad IV breast lesions.
Microscopy: The smears show mostly polymorphous lymphoid cells and tingible body
macrophages. The background contains blood. No atypical cells are seen.
Clinical Details: Swelling in submental region since 01yr. H/O increase in size. No h/o fever,
pain or weightloss. Soft to firm in consistency, measuring 3x4cm, 0.5cc of pus aspirated.
Microscopy: The smears show sheets of viable and degenerated, necrotic neutrophils.
Occasional histiocyte and multinucleate giant cell is also identified. Numerous chunks of
anuclear squames are also present.
Note : Differentials include infected sebaceous cyst and thyroglossal cyst. Please correlate
with clinical/ microbial culture findings.
Clinical Details: Swelling on right nasal ala for last02wks. H/O small pimple scratching
followed by this polypoid lesion. No h/o fever, pain or weightloss. Soft to firm in consistency,
measuring 1.5cm, necrotic and lobular surface.
Microscopy: The smears show sheets of viable and degenerated neutrophils. Occasional
stromal/ endothelial cell clusters are also identified.
CYTOLOGICAL FINDINGS
Clinical Notes: H/ofirm lump in right breast in LOQ for last 03days. Nodule measures 2x2cm.
No h/o tenderness, fever, cough, weight loss etc.Right axilla and nipple are not involved.
Microscopy: The smears are hypercellular showing three dimensional epithelial fragments.
These exhibit dispolarity and hyperchromasia and large atypical nuclei. Atypical epithelial cells
with high N/C ratio are also found scattered in the background of blood.
PAP SMEAR
CYTOLOGICAL FINDINGS
Note : The smear should at least cover 10% surface of the glass slide.
Report by Dr Asna Haroon Khan
(Al Rehman Medical Laboratory)
Specimen: CSF.
(About 01 ml of clear fluid received)
Clinical Notes: Fever, vomiting, headache with alert mental status. To ruleout malignancy
Microscopy: The smears are scantily cellular with fewdegenerated mature lymphocyte and
neutrophils.
Microscopy: The smears show mostly inflammatory cells, neutrophils mixed with few
lymphocytes and RBC. Occasional urothelial cells are also seen.
Opinion: Inflammation +
Negative for High Grade Urothelial Carcinoma
PAP SMEAR
CYTOLOGICAL FINDINGS
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Notes: Bilateral breast lumps in noticed 03yrs back. Mobile nontender, firm and
measure variably from 01 to 02cm. Largest in left breast LOQ was sampled. One was removed
from right about 02yrs ago.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with manyscattered bare nuclei. No evidence of malignancy
is seen.
Note : Please note that only the nodule on left was sampled.
Clinical Notes: Left lobe of thyroid for last 02yrs. No h/o pain , fever or increase in size. H/O
weight loss. About 100ml of fluid aspirated.
Microscopy: The smears are hypocellular with few inflammatory cells and mostly RBC.The
background is proteinaceous.
Clinical Details: H/O bilateral cervical nodes (1-2cm) for last 01yr, progressively increasing in
size. H/O low grade fever. No family hx of TB.
Microscopy: The smears show a population of mature lymphocytes mostly with some
immunoblasts. Occasional large cell is seen too. Few tingible body macrophages are seen. In the
background scattered eosinophils are present.
PAP SMEAR
CYTOLOGICAL FINDINGS
Microscopy: The smears are hypocellular with few lymphocyte and occasional mesothelial cell
showing degenerative changes. The background is clear.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Notes: H/olarge lump in left breast on lateral side for last 05months. Nodule measures
7x6.5cm. Nipple is fixed and retracted. H/O backache. No h/o fever, cough, weight loss etc.
BIRAD V.
Microscopy: The smears are hypercellular showing three dimensional epithelial fragments.
These exhibit dispolarity and hyperchromasia and large atypical nuclei. Atypical epithelial cells
with high N/C ratio are also found in the background of blood.
Microscopy:The smear is hypocellular with few mature looking adipocytes. The background
contains lipoid droplets and inflammatory cells.
Clinical Notes: Right cheek swelling x4months. No h/o fever, pain or weight loss. Oval lump
2x2cm with normal skin.
Microscopy: The smears comprise blood and its formed elements. No atypical cell is seen.
Opinion: Hemorrhagic Aspirate
Note : This may represent benign vascular lesion.Please correlate with clinical and
radiological findings.
Microscopy: The smears are hypercellular with many mature and degenarated neutrophils.
Occasional lymphocyte are seen in the background.
Clinical Notes: Enlarged thyroid for last 08months. No associated toxic symptoms. USG; MNG.
Microscopy: The smears are moderately cellular. Sheets of follicular cells are present.Few
hemosiderin laden macrophages are also seen in the background of blood mixed with thin
colloid.
Cell block is noncontributory.
Clinical Notes: Enlarged thyroid for last 01yr. Progressive increase in size for last 03months. No
associated toxic symptoms. Measure 6x4cm, nontender.
Microscopy: The smears are hypocellular. Few follicular cells are present in the background of
blood mixed with thin colloid.
Cell block is noncontributory.
Clinical Notes: Bilateral breast lumpsnoticed 5-6yrs back. Right sided operated 01wk ago.
FNAC of left side 03yrs ago. Three nodules palpable on left side in periareloar region. Mobile
nontender, firm and measure variably from 02 to 03cm.Largest one in IUQ was sampled.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present.Few fragments also show apocrine change. The background is of blood withscattered
bare nuclei. No evidence of malignancy is seen.
Microscopy: The smears are hypercellular with mostly lymphocytes and occasional neutrophil
and RBC. Mature and larger forms of the lymphocytes are seen in a clear background.
Opinion: Lymphocytosis
Clinical Notes: Lump in left face for 03yr. Gradually increasing in size. No associated oozing
or neuralgias.
Microscopy: The smears are hypocellular showing occasional stromal fragments and no
epithelial cells. The background comprises blood.
Note : The smears are inadequate for opinion , repeat FNAC/ tissue biopsy is suggested if
clinically indicated.
Clinical Notes:Multinodular thyroid, cystic in left lobe for last 09months. TSH value is 0.048.
T3 and T4 are WNL. Large 5x6cm nontender nodule.
Microscopy: The smears are hypocellular. Follicular cells are not present. Many hemosiderin
laden macrophages are also seen in the background of blood mixed with thin colloid.
Cell block shows blood mixed with many hemosiderin laden macrophages.
Clinical Notes: Left breast lump noticed 1.5month back. Mobile nontender, firm and measures
02x 02cm, in IUQ near the areola.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with many scattered bare nuclei. No evidence of
maliganacy is seen.
Microscopy: The smears are Moderately cellular with blood formed elements in protienaceous
background.
Clinical Notes: Breast lumpnoticed 2-3wks back. Mobile nontender, firm and measures from
02x 02cm. No family H/O breast pathology.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with scattered bare nuclei. No evidence of malignancy is
seen.
Clinical Notes: Enlarged thyroid for last 20yr. No associated toxic symptoms. Now increasing
in size and causing dysphagia and difficulty in breathing. Measures 08x07cm.
Microscopy: The smears are moderately cellular. Few clusters of follicular cells are present
and few chunks of thick colloid are also seen in the background of blood. Few clusters show
papillary architecture with vesicular oblong nuclei, cleaves and occasion inclusion like
morphology.
Note : Few clusters are suspicious for features of papillary carcinoma thyroid. However
drying artifacts are also present. Excision is suggested for definite diagnosis.
Clinical Notes: Breast lumpnoticed 05yr back. Mobile nontender, firm and now measures from
03x03cm. Has bourn 03 children with this and also breast fed them. Now lactating. No family
H/O breast pathology.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present. Occasional one shows apocrine change. The background of blood contains scattered
bare nuclei. No evidence of malignancy is seen.
Clinical Notes: Breast lumpnoticed 01yr back. Mobile nontender, firm and measures from
04x03cm in upper half of breast. No associated symptoms. No family H/O breast pathology.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present. The background of blood contains scattered bare nuclei. No evidence of malignancy
is seen.
Microscopy: The smears are hypocellular with mostly blood formed elements. There are
occasional small clumps with cells having irregular nuclear contours. No overt sign of
malignancy is seen. The background is clear.
Note : This may represent degenerative atypia, please correlate with clinical and
radiological findings.
Reported by Dr Asna Haroon Khan
(Al Rehman Medical Laboratory)
Clinical Details: Right cervical lump since 01yr. H/O increase in size. Previous FNAC was
reported to be hypocellular.
Microscopy: The smears are hypocellular with clumpedanuclear squames and amorphous
material. Occasional group of squamous cells and some keratin flakes are also identified. The
background shows few inflammatory cells.
Clinical Notes:Multinodular thyroid, more so in isthmus and left lobe for last 2-3months. No
H/O associated toxic symptoms. Chocolate colored fluid 02ml aspirated.
Microscopy: The smears are moderately cellular. Small clumps of benign looking follicular
cells are present.Numerous hemosiderin laden macrophages are also seen in the background of
blood mixed with thick colloid.
Clinical Details: H/O nodular swellings in right axilla, 02x1.5cm, mobile, nonadherant and
tender. H/O fever (PUO) for 01month. Treated for Hep C 7yrs ago
Microscopy: The smears show mostly polymorphous lymphoid cells and tingible body
macrophages. There are adipose tissue fragments also present. The background contains blood.
No atypical cells are seen.
Age/Sex: 30Y/M
Lab No : CYTO – 205/18
Date: 15-10-2018
Reference: Medpath Lab
Clinical Details: Swelling right cervical region since 01wk. H/O increase in size. H/O fever with
rigors and pain. No weightloss. Firm in consistency, measuring 5x4cm, 4.5cc of pus aspirated.
Microscopy: The smears show sheets of viable and degenerated, necrotic neutrophils.
Microscopy: The smears are moderately cellular with lymphocytes in thick protienaceous
background.
Clinical Details: H/O nodular swellings in left side of neck for last 01wk. It measures 02x1.5cm,
mobile, nonadherant and nontender. H/O pustule in scalp.
Microscopy: The smears show mostly polymorphous lymphoid cells and tingible body
macrophages. The background contains blood. No atypical cells are seen.
Clinical Details: Swelling right cervical region since 04months. H/O increase in size x 1month.
H/O fever fatigability and spontaneous rupture with pus discharge. No h/o weightloss. Firm to
soft in consistency, irregular, measuring 5x4cm. Small amount of pus aspirated.
Microscopy: The smears show sheets of viable and degenerated, necrotic neutrophils.
Clinical Notes: Left breast lumps for last 15yrs. Increase in sizenoticed 5-6yrs and now painful
for last 03months. Mobile tender, firm and measures 10x10cm in IUQ. Overlying skin is free
with prominent veins.
Microscopy: The smears are moderately cellular. Small to medium partly dyshesive ductal
epithelial fragments are present in a background of blood. Few stromal crushed fragments are
also present showing spindle morphology.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Details: Swelling upper eyelid. H/O increase in size and pain. No h/o fever and
weightloss. Firm in consistency, measuring 0.6cm, fixed to epidermis. Two passes were made
and very scanty aspirate obtained.
Microscopy: The smears show few epithelial/ squamous cells and some stromal fragments.
The background contains blood.
Clinical Notes: Right axillary lump noticed 05yr back. Now increasing in size. Mobile,
soft,nontender and measures 3x2cm.
Microscopy: The smears show cohesive smallto medium sized fragments of mature looking
adipose tissue. The background contains lipoid droplets.
Microscopy: The smears are hypercellular with lymphocyte and mesothelial cell in clear
background. There are many groups of medium to large atypical cells containing pleomorphic
nuclei.
Clinical Notes: Breast lump in left breast, noticed 10months back. Increasing in size gradually.
No h/o nipple discharge. It measures 10x10cm, slightly tender, overlying skin is red.
Microscopy: The smears are hypocellular with few fragments of atypical epithelium showing
large cells with high N/C ratio and moderate nuclear pleomorphism.Epithelial fragments are
present in a background of thick blood.
The cell block also shows few atypical cells.
Note : The smears are hypocellular however in the light of age and clinical information of
inflamed skin, Trucut biopsy is strongly suggested before embarking any major procedure.
Clinical Notes: Known thyrotoxic on neomercazole. Now c/o increase in goiter size. Scan shows
heterogenous hyper functioning nodule in left lobe and a cold nodule in right lobe.
Microscopy: The smears show small to medium sized clusters of follicular cells. These show
drying artifacts.Few hemosiderin laden macrophages are also seen in the background of blood.
Note : Side of the lobes sampled is not specified on the slides received.
Reported by Dr Asna Haroon Khan
(Al Rehman Medical Laboratory)
Microscopy: The smears are hypocellular with thick background of blood formed elements.
Clinical Notes: Swelling infront of neck, for last 1-2months. H/O insomnia, weightloss,
dyspnea, dysphagia and tachycardia. CT scan shows aggressive nodule in right lobe with
massive mediastinal lymphadenopathy. Pulmonary nodule in left upper lobe is also identified.
Note : The smears are inadequate for opinion , repeat FNAC is suggested if clinically
indicated.
Clinical Details: Left breast tender nodule (02cm) involving the subareolar region, noticed 3-
4months ago. No h/o increase in size, fever, nipple discharge or weight loss. No Family history
of breast pathology.
Microscopy : The smears are hypocellular with few tiny, cohesive fragments of ductal
epithelium seen along with many adipose tissue fragments. Atypia, mitoses or necrosis are not
identified. The background shows blood.
Clinical Details: H/O right thyroid swelling (2x3cm) for last 1.5months. Firm, mobile and
progressively increasing in size. No H/O associated symptoms, though appetite is increased and
sleep is reduced.
Microscopy: The smears show medium to small clusters of follicular cells are present. These
shows enlarged nuclei with overlapping and occasional cleaves. These show some drying
artifacts. In the background is formed by blood.
Note : Please correlate with clinical findings. Also refer to Histopathology report # S- 1217-
2018 of the same patient.
Clinical Notes: Nodular thyroid swelling for last 02yrs. No associated toxic symptoms.
Multiple nodules on USG. Isthmic nodule FNAC done.
Microscopy: The smears are moderately cellular. Macro and microfollicles of normal looking
cells are present.Few hemosiderin laden macrophages are also seen in the background of blood
mixed with colloid.
Clinical Notes: Thyroid swelling for last 01month. H/O associated weakness. No associated
toxic symptoms. Multiple nodules on USG. Nodule visible on left side.
Microscopy: The smears are hypocellular. Occasional follicular cells of normal looking
morphology are present.Few hemosiderin laden macrophages are also seen in the background of
blood mixed with thin colloid.
Microscopy: The smears are moderately cellular with mixed inflammatory cells predominantly
lymphocytes. Occasional mesothelial cell is seen in a proteinaceous background.
Clinical Details: Right breast tender nodule (7x5cm), noticed 15days ago. No h/o fever.
Breastfeeding a 02yr old child.
Microscopy : The smears are moderately cellular with many fragments of ductal epithelium.
These show abundant cytoplasm. Few foamy histiocytes and multinucleate giant cells are also
seen in a hemorrhagic background. Atypia, mitoses or necrosis are not seen.
Specimen: Fluid.
(About 10 ml of reddish fluid received)
Microscopy: The smears are hypocellular with only blood formed elements with increased
mature lymphocytes in the background.
Clinical Details: right breast mildly tender nodule (2x2cm) involving the LOQ, noticed 08year
ago. Now gives pain, No h/o fever or weight loss. Breastfeeding a 02month old child. Whitish
milky fluid aspirated.
Microscopy : The smears are moderately cellular with many foamy histiocytes in a
protienaceous background. The latter contains few inflammatory cells too. Few cohesive
fragments of ductal epithelium are also identified. Atypia, mitoses or necrosis are not seen.
Microscopy:The smear is hypocellular with rare cohesive tiny fragments of mature looking
adipose tissue. The background contains blood.
Microscopy: The smears comprise blood and its formed elements. Occasional stromal
component and epithelial cells are also seen. No atypical cell is seen.
Microscopy: The smears are hypocellular with occasional lymphocyte and degenerated cells.
The background is clear.
Note : Please also see histopathology report # S – 1273/18 of the same patient.
Microscopy: The smears comprise blood and its formed elements. Occasional stromal
component is also seen. No atypical cell is seen.
Clinical Notes: Swelling in left thigh, progressively increasing in size for last 02 months.
Similar smaller swelling on left arm.
Microscopy:The smear is moderately cellular with cohesive tiny fragments of mature looking
adipose tissue. The background contains lipoid droplets.
Microscopy: The smears are hypocellular with only blood formed elements like mature
lymphocytes and many hemosiderin laden macrophagesin the background with
Note : Please also see histopathology report # S-1293-2018 of the same patient.
PAP SMEAR
CYTOLOGICAL FINDINGS
Microscopy: The smears are hypercellular with mostly lymphocytes and RBC. Mature as well
as larger forms of the former are seen in the protienaceous background. Some also show irregular
nuclear contours.
Opinion: Lymphocytosis
Suspicious for Atypia
Microscopy: The smears are hypercellular with mostly lymphocytes and RBC. Mature as well
as larger/ activated forms of lymphocytes are seen in the protienaceous background.
Opinion: Lymphocytosis
Clinical Notes: Swelling infront of neck ( thyroid nodule) for last 8-9yr. Feels dyspnoeic for
last one year but no associated toxic symptoms. Thyroid function tests are within normal limits.
MNG on USG.
Microscopy: The smears are hypocellular. Occasional tiny clumps of follicular cells are present.
Many hemosiderin laden macrophages are also seen in the background of blood mixed with thin
colloid.
Clinical Notes: Right breast lump, in IUQ,following spontaneous rupture of breast abscess
05months back. Mobile nontender, firm and measures 3.5x04cm.
Microscopy: The smears are hypocellular. Occasional cohesive ductal epithelial fragmentis
present in a background of blood mixed with few inflammatory cells. No evidence of
malignancy is seen.
Clinical Notes: Right axilla lump for last 01month. Mobile nontender, firm and measures
1.5x03cm. Straw colored fluid aspirated in needle butt.
Microscopy: The smears are hypocellular. Occasional cohesive ductal epithelial fragmentis
present in a background of blood mixed with few inflammatory cells and histiocytes. The
background is proteinaceous. No evidence of malignancy is seen.
Clinical Details: H/O bilateral cervical lymphadenopathy for last 01month. No history of fever
or other symptoms . Largest palpable 04cm submantle.
Microscopy: The smears show sheets atypical lymphoid cells many showing crushing as well.
These have large nuclei with open chromatin with streaking effect. The cytoplasm is negligible
and nucleoli are prominent. Afew multinucleate forms are also seen. In the background there
are similar lymphoid cell present.
Microscopy: The smears are hypocellular. Afew clusters of inflammatory cells are also
identified. There are few scattered cells withlarge vesicular nuclei also present. These show rare
membrane irregularity too. In the background colloid, histiocytes and calcific spherules are also
present.
Notes : Morphology is suspicious of PTC nuclear features, however opinion is limited due
to hypocellularity. Excision is suggested.
Microscopy: The smears are hypercellular with lymphocyte and occasional mesothelial cell in
clear background. There are groups of large atypical cells seen with pleomorphic nuclei
exhibiting nuclear membrane.
PAP SMEAR
CYTOLOGICAL FINDINGS
Clinical Notes: Hard lump on upper right leg following a trauma about 6yrs ago. MRI shows
calcified nodule separate from bone in soft tissue. OE; 3x4cm hard tender lump below right
fibula head.
Microscopy: The smears comprise blood and its formed elements. No atypical cell is seen.
Clinical Notes: Right axillary lump noticed 01yr back. Now increasing in size. Mobile,
soft,nontender and measures 5x5cm. No nipple discharge or association with M/cycle.
Microscopy: The smears show few cohesive small sized fragments of mature looking adipose
tissue. The background contains lipoid droplets and blood.
Clinical Notes: Thyroid coldnodule in isthmus for last 04months. Feels dyspnoeic but no
associated toxic symptoms.Para10 with7 alive issues, LCB 04yrs.
Microscopy: The smears are moderately cellular. There are cellswith enlarged nuclei. Clusters
of cells are also identified with overlapping and occasional grooves. Vague papillary forms are
also seen. In the background blood formed elements are seen.
Clinical Notes: Left breast lump noticed 01wk back. Mobile nontender, firm and measures 1-
2cm. No axillary involvement. Family h/o Ca breast- mother.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with few scattered bare nuclei. No evidence of malignancy
is seen.
Microscopy: The smears are hypocellular with occasional lymphocyte and degenerated cells.
The background is clear.
Note : The sample is degenerated, thus the opinion is limited. Please also see histopathology
report # S – 1385/18 of the same patient.
Reported by Dr Asna Haroon Khan
(Al Rehman Medical Laboratory)
Clinical Notes: Left breast lump noticed 3months back. Mobile nontender, firm and measure
variably from 1.5cm in outer lower quadrant. No nipple or axillary involvement.
Microscopy: The smears are hypercellular. Branched cohesive ductal epithelial fragments are
present. In a background of blood scattered bare nuclei and many histiocytes are present . No
evidence of malignancy is seen.
Clinical Notes: Breast lump in IUQ on rightside, noticed some time ago. Now pregnant
02months and wanted checkup. Mobile nontender, firm and measures 02cm.
Microscopy: The smears are moderately cellular. Branched cohesive ductal epithelial fragments
are present in a background of blood with many scattered bare nuclei. No evidence of
malignancy is seen.
Clinical Notes: Breast lump in LOQ, periareolar on rightside, noticed 05months back. Mobile
nontender, firm and measures 02cm. No associated symptoms.
Microscopy: The smears are hypercellular. Branched cohesive ductal epithelial fragments are
present in a background of blood with many scattered bare nuclei. No evidence of malignancy is
seen.
The sections show fibrin clots and necrotic/ inflamed tissue fragments. Scanty fragments of
decidualized stroma / cytotrophoblast are also present. There is no evidence of atypia or
malignancy.
The specimen consists of dark brown fragments measuring 0.5x1x0.5cm, entirely embedded as such, in
one cassette.