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Dosage, Route,

Name of Drug Frequency and Mechanism of Action Indication Adverse Reactions Special Precautions Nursing Responsibilities
Timing
Generic: Dosage: 5 mg Nonselectively blocks Schizophrenia and Extrapyramidal Administered 1. Assess behavior, appearance,
Haloperidol postsynaptic dopamine manic states symptoms (EPS) cautiously to patients emotional status, response to
receptors in the brain, appear to be dose with severe environment, speech pattern,
Route: PO thereby producing related and typically impairment of liver thought content.
tranquilizing effect. occur in first few days or kidney function, 2. Assess mental status.
Brand: Zuredel of therapy. Marked and to patients with 3. Screen for comorbidities
Frequency: BID It has strong drowsiness/ lethargy, known allergies to (esp. seizure disorder, long
extrapyramidal, excessive salivation, other neuroleptic QT syndrome).
antiemetic effects; fixed stare may be mild drugs. 4. Monitor BP, heart rate.
Timing: 8, 6 weak anticholinergic, to severe in intensity. 5. Monitor ECG, QT interval.
sedative effects. Less frequently noted PATIENT/FAMILY 6. Supervise suicidal-risk pts
are severe akathisia TEACHING closely during early therapy
(motor restlessness), ● Full therapeutic (as depression lessens,
acute dystonias: effect may take energy level improves,
torticollis (neck muscle up to 6 wks. increasing suicide potential).
spasm), opisthotonos ● Do not abruptly 7. Monitor for rigidity, tremor,
(rigidity of back withdraw from mask-like facial expression,
muscles), oculogyric long-term drug fine tongue movement.
crisis (rolling back of therapy. 8. Assess for therapeutic
eyes). Tardive ● Drowsiness response (interest in
dyskinesia (tongue generally surroundings, improvement
protrusion, puffing of subsides during in self-care, increased ability
cheeks, continued to concentrate, relaxed facial
chewing/puckering of therapy. expression).
the mouth) may occur ● Avoid alcohol. 9. Provide sips of water when
during long-term ● Report muscle patient reports of dry mouth
therapy or after drug stiffness, lip
discontinuance and puckering, tongue
may be irreversible. protrusion,
Elderly female pts have restlessness.
greater risk of devel- ● Avoid
oping this reaction. overheating,
May increase risk of dehydration,
QT interval exposure to
prolongation, cardiac sunlight
arrhythmias. (increased risk
of heatstroke).
Classification Contraindications Side Effects
Functional: Patients in severe ● Blurred vision,
First- depressive states or ● constipation,
generation comatose states and ● orthostatic
(typical) with sensitivity to hypotension,
antipsychotic haloperidol. ● dry mouth,
● peripheral edema.
● Allergic reaction,
● difficulty urinating,
Chemical: ● decreased thirst,
C21H23ClFNO ● dizziness,
2 ● diminished sexual
function,
● drowsiness,
● nausea,
● vomiting,
● photosensitivity,
● lethargy.

Student’s Name: __________________________________________


Clinical Instructor: _________________________________________

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