Test Bank for Roachs Introductory Clinical Pharmacology, 9th Edition: Ford

Test Bank for Roachs Introductory Clinical

Pharmacology, 9th Edition: Ford

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Name: __________________________ Date: _____________

1. In general, progression from first-generation cephalosporins to fourth-generations

results in which of the following? Select all that apply.
A) An increase in sensitivity of gram-negative microorganisms.
B) A decrease in sensitivity of gram-negative microorganisms.
C) An increase in sensitivity of gram-positive microorganisms.
D) A decrease in the sensitivity of gram-positive microorganisms.
E) An increase in the sensitivity of viral microorganisms.

2. Cephalosporins are used to treat which of the following infections? Select all that apply.
A) Urinary tract infections
B) Bone infections
C) Skin infections
D) Community acquired pneumonias
E) Nosocomial pneumonias

3. Cephalosporins may be used throughout the perioperative procedure, including which of

the following? Select all that apply.
A) Postoperative period
B) Prophylactic period
C) Intraoperative period
D) Post-exposure period
E) Preoperative period

4. Which of the following should a nurse recognize as serious adverse reactions that can
occur with the use of cephalosporins? Select all that apply.
A) Toxic epidermal necrolysis (TEN)
B) Aplastic anemia
C) Nephrotoxicity
D) Stevens-Johnson syndrome (SJS)
E) Anaphylactic reaction

5. Common adverse reactions to cephalosporins include which of the following? Select all
that apply.
A) Drowsiness
B) Headache
C) Constipation
D) Heartburn
E) Vomiting

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 6. Which of the following is true of cephalosporins given via injection? Select all that
apply.
A) Thrombophlebitis can occur when cephalosporins are given IV.
B) Phlebitis can occur when cephalosporins are given IM.
C) Pain can occur when cephalosporins are given IM.
D) Tenderness can occur when cephalosporins are given IM.
E) Swelling can occur when cephalosporins are given IM.

7. Which of the following is a superinfection that may occur in a client being given a
cephalosporin? Select all that apply.
A) Osteomyelitis
B) Vaginal candidiasis
C) Pseudomembranous colitis
D) Otitis media
E) Conjunctivitis

8. Cephalosporins should be used cautiously in clients with which of the following? Select
all that apply.
A) Diabetes
B) Renal disease
C) Hepatic impairment
D) Bleeding disorder
E) Known penicillin allergy

9. What symptoms might a nurse observe in a client having a disulfiram-like reaction with
administration of a cephalosporin and alcohol? Select all that apply.
A) Flushing
B) Respiratory difficulty
C) Hypertension
D) Vomiting
E) Sweating

10. Which of the following should be included in the nurse's pre-administration assessment
prior to a client receiving a cephalosporin? Select all that apply.
A) Allergy history
B) Medical history
C) Medication history
D) Blood glucose
E) Current symptoms

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11. Which of the following is an example of a first generation cephalosporin? Select all that
apply.
A) Cefadroxil (Duricef)
B) Cefazolin (Ancef)
C) Cefprozil (Cefzil)
D) Cephalexin (Keflex)
E) Cefaclor (Raniclor)

12. During ongoing assessment of a client receiving cephalexin (Keflex), the nurse should
monitor the client for which of the following? Select all that apply.
A) Relief of symptoms
B) Development of a rash
C) Increase in appetite
D) Change in appearance or amount of drainage
E) Decrease in temperature

13. Which of the drug-specific nursing diagnoses may be used in the administration of a
cephalosporin? Select all that apply.
A) Risk for impaired comfort
B) Risk for impaired skin integrity
C) Diarrhea
D) Impaired urinary elimination
E) Ineffective tissue profusion

14. Which of the following cephalosporins' absorption is increased when administered with
food? Select all that apply.
A) Cefuroxime (Ceftin)
B) Cephalexin (Keflex)
C) Ceftibuten (Cedax)
D) Cefixime (Suprax)
E) Cefpodoxime (Vantin)

15. Which of the following information should the nurse obtain from the manufacturer's
package insert when preparing to administer a cephalosporin via a parenteral route?
Select all that apply.
A) Instructions regarding reconstitution
B) Storage of unused portions
C) Life of drug after reconstitution
D) Methods of IV administration
E) Precautions to be taken during administration

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16. When skin irritation is present during the administration of a cephalosporin, the nurse
should advise the client to avoid which of the following? Select all that apply.
A) Harsh soaps
B) Perfumed lotions
C) Antipyretic creams
D) Rubbing the area
E) Wearing rough or irritating clothing

17. The nurse should advise a client to contact the physician immediately if which of the
following occur during treatment with a cephalosporin? Select all that apply.
A) Vomiting occurs.
B) Severe diarrhea occurs.
C) Vaginal itching occurs.
D) Skin rash or hives occur.
E) Sores in mouth occur.

18. The physician writes an order for a pediatric client to receive cephalexin (Keflex) 500
mg twice daily for 10 days. The client is unable to swallow tablets, but the cephalexin is
available in a 250 mg/5 ml suspension. How many teaspoonfuls will the client receive at
each dose?

19. The physician writes an order for a client to receive cefixime (Suprax) 400 mg daily for
14 days. Suprax is available in a 250 mg/5 mL suspension. How many mL will the
client need for 14 days?

20. The physician orders cefdinir (Omnicef) 300 mg by mouth every 12 hours for a client.
The client is unable to swallow tablets due to swelling in the throat and mouth.
Omnicef is available in a 125 mg/5 mL suspension. How many mL will the nurse need
to prepare for each dose?

21. A health care center is conducting a seminar on cephalosporins drugs. During the
question-and-answer period, the audience wants examples of conditions that can be
treated by cephalosporins. Which of the following infections should the nurse state as
examples?
A) Hemolysis
B) Urinary tract infections
C) Nausea and diarrhea
D) Jaundice

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22. Which of the following should a nurse carefully monitor in a patient who has been
administered cephalosporin as well as aminoglycosides for a wound infection?
A) Nausea
B) Nephrotoxicity
C) Increased bleeding
D) Respiratory difficulty

23. A nurse needs to administer a cephalosporin to a patient. The patient informs the nurse
that he is allergic to penicillin. Which of the following actions is the nurse most likely to
take in such a situation?
A) Inform the primary health care provider.
B) Obtain patient's occupational history.
C) Administer an antipyretic drug.
D) Suggest kidney function tests.

24. The nurse administers cefuroxime to a patient at least one hour before meals, as
prescribed. However, the patient experiences a GI upset. Which of the following is an
appropriate nursing intervention in this case?
A) Administer an antacid.
B) Lower the dosage.
C) Discontinue the drug.
D) Administer the drug with food.

25. A 75-year-old patient with a history of renal impairment is admitted to the primary
health care center with a UTI and has been prescribed a cephalosporin. Which of the
following interventions is most important for the nurse to perform when caring for this
patient?
A) Monitoring fluid intake.
B) Monitoring blood creatinine levels.
C) Testing for occult blood.
D) Testing for increased glucose levels.

26. An 8-year-old female patient visits the health care center with her mother. Her mother
informs the nurse that the child began taking a cephalosporin two days ago for treatment
of tonsillitis. To address a nursing diagnosis of impaired skin integrity, which of the
following actions should the nurse encourage the patient to follow?
A) Apply sunscreen on skin.
B) Avoid wearing rough clothes.
C) Wear clothes with long sleeves.
D) Avoid consumption of alcohol.

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27. A patient is being treated for a lung infection by the health care facility. The nurse is
required to administer powder ceftibuten to the patient. Which of the following nursing
interventions is appropriate when administering this powder cephalosporin?
A) Keep drug powder refrigerated until it is used.
B) Warm the oral suspension before use.
C) Mix the drug powder with fruit juice.
D) Administer the drug along with food.

28. Patients taking antibiotics, especially cephalosporins, are susceptible to superinfection,

so the nurse wants to ensure that they are aware of the signs and symptoms of
superinfections. Which of the following should the nurse mention as the symptoms of
superinfections?
A) Headaches
B) Constipation
C) Abdominal cramps
D) Cough and cold

29. A nurse is preparing the medical history report of a patient with a urinary tract infection.
Which of the following conditions should the nurse identify as one in which the use of
cephalosporins is restricted?
A) Aplastic anemia
B) Renal disease
C) Abdominal cramps
D) Headache

30. A patient who was administered cephalosporins has developed a skin rash. The nursing
assistant is scared and thinks that this is a serious reaction. The nurse tells him that this
is a mild reaction. Which of the following should the nurse mention as the symptoms of
serious hypersensitivity reaction?
A) Pruritis
B) Skin rashes
C) Renal dysfunction
D) Urticaria

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Test Bank for Roachs Introductory Clinical Pharmacology, 9th Edition: Ford

Answer Key
1. A, D
2. A, B, C, E
3. A, C, E
4. A, B, C, D, E
5. B, D, E
6. A, C, D, E
7. B, C
8. B, C, D, E
9. A, B, D, E
10. A, B, C, E
11. A, B, D
12. A, B, C, D, E
13. A, B, C, D
14. A, E
15. A, B, C, D, E
16. A, B, D, E
17. A, B, C, D, E
18. Two teaspoonfuls per dose
19. 112 mL
20. 12 mL
21. B
22. B
23. A
24. D
25. B
26. B
27. A
28. C
29. B
30. C

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