Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice 11th Edition Test Bank

Abrams’ Clinical Drug Therapy: Rationales for

Nursing Practice 11th Edition Test Bank

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1. An obese client who has an elevated triglyceride level and reduced high-density
lipoprotein cholesterol is seen by the primary care provider. What do these data suggest
in this client?
A) the development of arthritic syndrome
B) the development of metabolic syndrome
C) the development of Reye's syndrome
D) the development of Tay-Sachs disease

2. A client has an elevated total serum cholesterol of 260 mg/dL. Which aspect of client
teaching of lifestyle changes is most important for the client?
A) Eat organic foods.
B) Stop smoking.
C) Increase rest periods.
D) Drink whole milk.

3. A client with a diagnosis of cardiovascular disease is taking atorvastatin to reduce serum

cholesterol. What is the goal of therapy for LDL cholesterol for a client taking
atorvastatin calcium?
A) 100 to 115 mg/dL
B) 75 to 85 mg/dL
C) less than 60 mg/dL
D) less than 130 mg/dL

4. A client is taking atorvastatin to reduce serum cholesterol. Which aspect of client

teaching is most important?
A) Call the health care provider if muscle pain develops.
B) It is unacceptable to eat dietary fats.
C) Decrease the dose if lethargy occurs.
D) Eat two eggs per day to increase protein stores.

5. A client has begun taking cholestyramine. Which are noted as the most common
adverse effects?
A) nausea, flatulence, and constipation
B) increased appetite and blood pressure
C) fatigue and mental disorientation
D) hiccups, nasal congestion, and dizziness

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 6. A client who has been taking a statin has seen an improvement in cholesterol laboratory
values; however, the low-density lipoprotein remains elevated. What medication will be
added to the medication regimen?
A) digoxin
B) vitamin D
C) cholestyramine
D) calcium carbonate

7. A client is taking cholestyramine to reduce LDL cholesterol. Cholestyramine will cause

a decrease in absorption of which medication?
A) digoxin
B) ibuprofen
C) aspirin
D) acetaminophen

8. A client is prescribed fenofibrate. When providing client teaching, which accurately

describes the action of fenofibrate?
A) It binds to bile acids in the intestinal lumen.
B) It increases oxidation of fatty acids in the liver.
C) It inhibits an enzyme required for hepatic synthesis.
D) It inhibits mobilization of free fatty acids from peripheral tissues.

9. Which single drug class is known to be most effective in reducing the major types of
dyslipidemia?
A) statins
B) bile acid sequestrants
C) fibrates
D) niacin

10. A client is taking cholestyramine and ezetimibe. What administration guideline is most
important to teach this client?
A) The two medications should be taken together.
B) The ezetimibe inhibits cholesterol in the liver.
C) The cholestyramine is administered 1 hour after ezetimibe.
D) The administration of ezetimibe is 1 hour before cholestyramine.

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11. A client has been reading about the use of flax seed to lower cholesterol. What should
the client be taught about the use of oat bran and cholestyramine?
A) Cholestyramine absorption will be increased with oat bran.
B) Cholestyramine absorption will be decreased with oat bran.
C) Bleeding will be increased with oat bran and cholestyramine.
D) Hypoglycemia will result from oat bran and cholestyramine.

12. Which herbal and dietary supplement has shown proven success in lowering LDL and
total cholesterol in research studies?
A) soy
B) flaxseed oil
C) red yeast rice
D) garlic

13. A client is scheduled to have serum triglyceride level assessed. How long should the
client be without food or fluids prior to the serum triglyceride test?
A) 6 hours
B) 8 to 10 hours
C) 12 hours
D) 24 hours

14. An older adult client, who leads a sedentary lifestyle, has recently been diagnosed with
dyslipidemia. The client is disappointed to learn about this condition, stating, “First it
was the diabetes and then the arthritis, now this.” The nurse has performed health
education with the client and has described metabolic syndrome. In addition to the
elevated cholesterol levels, what aspect of the client's health is congruent with a
diagnosis of metabolic syndrome?
A) sedentary lifestyle
B) age over 65
C) arthritis
D) diabetes mellitus

15. A male client has been diagnosed with moderately increased LDL, and his primary care
provider wishes to begin him on a statin. What is a potential disadvantage of statins that
the care provider should consider? Select all that apply.
A) Statins are nephrotoxic.
B) Statins are expensive.
C) Statins are contraindicated in clients with a history of myocardial infarction.
D) Statins require regularly scheduled blood work.
E) Statins have an immunosuppressive effect.

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16. A client will begin taking atorvastatin, and the nurse is conducting relevant health
education. The nurse should emphasize the need to report any new onset of:
A) muscle pain.
B) dry mouth.
C) pruritus (itching).
D) increased thirst.

17. An older adult client is being treated in the hospital for a stroke and is undergoing an
extended stay on a rehabilitation unit. The client's spouse has been participating actively
in the client's care and performs much of the feeding and hygiene needs. This evening,
the spouse has brought in a number of healthy snacks to keep at the client's bedside.
Knowing that the client's medication regimen includes simvastatin, the nurse would
remove which item?
A) purple grapes
B) cranberry cocktail
C) grapefruit juice
D) trail mix (salted nuts and seeds)

18. A client has been largely unsuccessful in achieving adequate control of dyslipidemia
through lifestyle changes and the use of a statin. As a result, the client has been
prescribed cholestyramine. What change in this client's lipid profile will the nurse
identify as the most likely goal of therapy?
A) reduction in triglycerides
B) reduction in total serum cholesterol levels
C) increase in HDL levels
D) reduction in LDL cholesterol levels

19. A 66-year-old woman's most recent physical assessment and diagnostic workup reveal
the presence of dyslipidemia. The woman is a candidate for monotherapy with a statin,
and she will soon begin treatment with atorvastatin. The nurse should anticipate what
order?
A) “atorvastatin 150 mg PO BID”
B) “atorvastatin 10 mg PO OD”
C) “atorvastatin 50 mg PO TID with meals”
D) “atorvastatin 75 mg PO BID”

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20. An elderly client with dyslipidemia has had fenofibrate added to the existing medication
regimen. In addition to having the lipid profile drawn on a regular basis, the nurse
should educate the client about the need for what ongoing laboratory testing during
therapy?
A) complete blood count (CBC)
B) liver panel
C) INR and aPTT
D) reticulocyte count

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Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice 11th Edition Test Bank

Answer Key
1. B
2. B
3. D
4. A
5. A
6. C
7. A
8. B
9. A
10. D
11. A
12. C
13. C
14. D
15. B, D
16. A
17. C
18. D
19. B
20. B

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