Skin Cancer

(Part 1)

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 Skin Cancer (Part 1)

Squamous Cell Keratoacanthom Basal Cell

Carcinoma a Carcinoma

CC (0) James Heilman, M.D. Modifications © 2019 BoardsMD CC (3.0) John Hendrix
made.

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 Squamous Cell Carcinoma
• Presentation: Hyperkeratotic papule, plaque, or nodule
• May have areas of ulceration, hemorrhage, or necrosis
• Sun-exposed areas: Hand, scalp, pinna, lower lip
• Slow-growing

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 Squamous Cell Carcinoma

Ulceration

CC (0) Public Domain. Kelly CC (0) James Heilman, M.D. Modifications

Nelson. made.

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 Squamous Cell Carcinoma
Actinic keratoses of the hand
• Pathophysiology: UV exposure
• May arise de novo or from actinic keratosis
• ↑ risk in immunocompromised
• Radiation, Arsenic, Lighter skin

CC (4.0) James Heilman, M.D. Modifications

made.

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 Squamous Cell Carcinoma
Dx: Biopsy => Keratin pearls

CC (4.0) Calicut Medical College

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 Squamous Cell Carcinoma
• Mgmt: Mohs Micrographic Surger y (MMS)
• Standard excision
• Curettage and electrodesiccation (C&E)
• If high-risk => + Radiation
• If refractory or metastatic => + Chemo

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Keratoacanthoma

Central keratin plug

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Keratoacanthoma

Central keratin plug

Jmcarhn CC (3.0). Modifications made.

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Marjolin Ulcer

CC (0) Raj d0509

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 Basal Cell Carcinoma
• Presentation: Upper face, arms, trunk
• Nodular: Pink, pearly papule, often with telangiectasias +/- rolled borders
• Superficial: Pink to light-red, scaly macules, patches, or thin plaques
• Morpheaform: Flesh-colored or light pink papule/plaque with ill-defined
borders
Telangiectasias
• Slow-growing and locally invasive

CC (3.0) John Hendrix. Modifications made.

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 Basal Cell Carcinoma
• Pathophysiology: UV exposure
• Lighter-skinned patients

CC (3.0) James Heilman, MD

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 Basal Cell Carcinoma
• Dx: Biopsy

• Mgmt: Mohs Micrographic Surger y (MMS)

• If superficial BCC or poor surgical candidate => 5-Fluorouracil or Imiquimod

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High-Yield Summary
Squamous cell carcinoma
• Presentation: Ulcerated papule with scale
• Sun-exposed areas: Hand, scalp, pinna, lower lip
• Slow-growing
• Pathophysiology: UV exposure
• May arise de novo or from actinic keratosis
• ↑ risk in immunocompromised
• Radiation, Arsenic, Lighter skin
• Dx: Biopsy => Keratin pearls
• Mgmt: Mohs Micrographic Surgery (MMS)
• If palpable local nodes => + Radiation, Node resection
• If distant metastases => + Chemo
Basal cell carcinoma
• Presentation: Shiny, pearly, ulcerative nodule
• Upper face, arms, trunk
• Blood vessels running through it
• Slow-growing and locally invasive
• Pathophysiology: UV exposure
• Lighter-skinned patients
• Dx: Biopsy
• Mgmt: Mohs Micrographic Surgery (MMS)
• If superficial BCC or poor surgical candidate => 5-Fluorouracil or
Imiquimod
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 High-Yield Summary
Squamous Cell Keratoacanthom Basal Cell
Carcinoma a Carcinoma

CC (0) James Heilman, M.D. Modifications © 2019 BoardsMD CC (3.0) John Hendrix
made.

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