Test Bank for Brown and Mulholland’s Drug Calculations 11th Edition by Tritak

Test Bank for Brown and Mulholland’s Drug

Calculations 11th Edition by Tritak

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Chapter 06: Reconstitution of Medications from Powders and Crystals: Oral and
Intramuscular
Tritak: Brown and Mulholland’s Drug Calculations: Ratio and Proportion Problems
for Clinical Practice, 11th Edition

ESSAY

Directions: Answer the questions below.

1. Ordered: 500,000 units Pfizerpen IM q6h.

Available: Pfizerpen 1 million units for reconstitution.
Directions for mixing: Add 18.2 mL diluent to yield 250,000 units per mL or add 3 mL
diluent to yield 1,000,000 units per mL.
How many mL will you give if you use 18.2 mL of diluent?

ANS:
2 mL

Have Want to Have

250,000 units : 1 mL = 500,000 units : x mL
25 x = 1  50 = 50
x = 2 mL

Proof: 1  50 = 50
25  2 = 50
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2. Ordered: Principen 200 mg po q6h.
Available: Principen (ampicillin) for oral suspension.
Directions: Add 72 mL of water. Shake well to make 100 mL. Each 5 mL yields 125 mg of
ampicillin.
How many mL will you give?

ANS:
8 mL

Have Want to Have

5 mL : 125 mg = x mL : 200 mg
125 x = 5  200 = 1000
x = 8 mL

Proof: 5  200 = 1000

125  8 = 1000

3. Ordered: Measles, mumps, and rubella virus vaccine 0.5 mL subcutaneous.

Available: 10 mL multidose vial.
Directions: Use only the special diluent supplied for reconstitution. Withdraw the entire
content (7 mL) of diluent and inject into the sterile vial of vaccine. Agitate to ensure thorough
mixing. Each dose is 0.5 mL.

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How many doses are in the vial?

ANS:
20 doses

Have Want to Have

0.5 mL : 1 dose = 10 mL : x dose
0.5 x = 1  10 = 10
x = 20 doses

Proof: 0.5  20 = 10
1  10 = 10

4. Ordered: Methicillin 750 mg IM q6h.

Available: Methicillin sodium 1 g.
Directions: Add 5.7 mL sterile water for injection. Each 2 mL equals 1 g methicillin sodium.
Discard after storing 24 hr at room temperature or after 4 days of refrigeration.
How many mL will you inject?

ANS:
1.5 mL

Have Want to Have

2 mL : 1000 mg = x mL : 750 mg
1000x = 2  750 = 1500
x = 1.5 mL
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Proof: 2  750 = 1500
1.5  1000 = 1500

5. Ordered: Penicillin G potassium 250,000 units IM q8h.

Available: Penicillin G potassium 1 million units.
Directions: Add 9.6 mL diluent for 100,000 units/mL. Add 4.6 mL diluent for 200,000
units/mL. Add 1.6 mL diluent for 500,000 units/mL.
How many mL will you give if you add 4.6 mL diluent to the powder?

ANS:
1.3 mL

Have Want to Have

200,000 units : 1 mL = 250,000 units : x mL
20x = 25
x = 1.25 = 1.3 mL

Proof: 1  25 = 25
20  1.25 = 25

6. Ordered: Ampicillin 350 mg IM q6h.

Available: Ampicillin 1 g.

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Directions: Add 3.5 mL diluent. Each mL equals 250 mg.

How many mL will you give?

ANS:
1.4 mL

Have Want to Have

250 mg : 1 mL = 350 mg : x mL
25x = 1  35 = 35
x = 1.4 mL

Proof: 1  35 = 35
25  1.4 = 35

7. Ordered: Cefadyl 400 mg IM q6h.

Available: Cefadyl 1g.
Directions: Add 2 mL Bacteriostatic Water for injection. Each 1.2 mL contains 500 mg of
cephapirin.
How many mL will you inject?

ANS:
1 mL

Have Want to Have

500 mg : 1.2 mL = 400 mg : x mL
5x = 1.2  4 = 4.8
x = 0.96 = 1 mL GRADESMORE.COM

Proof: 5  0.96 = 4.8

1.2  4 = 4.8

8. Ordered: Pfizerpen 600,000 units IM q12h.

Available: Pfizerpen 5 million units.
Directions: Add 8.2 mL diluent to yield 500,000 units/mL. Add 3.2 mL diluent to yield
1,000,000 units/mL.
If you add 8.2 mL of diluent, how many mL of Pfizerpen will you give?

ANS:
1.2 mL

Have Want to Have

500,000 units : 1 mL = 600,000 units : x mL
5x = 6
x = 1.2 mL

Proof: 1  6 = 6
5  1.2 = 6

9. Ordered: Ticar 0.5 g.

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Available: Ticar 1g.

Directions: Add 2 mL sterile water for injection or 1% lidocaine HCl (without epinephrine).
Each 2.6 mL equals 1000 mg of Ticar.
How many mL will you give?

ANS:
1.3 mL

Have Want to Have

2.6 mL : 1000 mg = x mL : 500 mg
10x = 2.6  5 = 13
x = 1.3 mL

Proof: 2.6  5 = 13
10  1.3 = 13

10. Ordered: Rocephin 500 mg IM bid.

Available: Rocephin 0.5 g vial.
Directions: Add 1.8 mL of diluent to yield 250 mg/mL. Add 1 mL of diluent to yield 350
mg/mL.
How many mL will you give if you add 1 mL of diluent?

ANS:
1.4 mL

Have Want to Have

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350 mg : 1 mL = 500 mg : x mL
350x = 500
x = 1.428 = 1.4 mL

Proof: 1  500 = 500

350  1.428 = 499.8 = 50

Directions: Mark the amount to be given on each syringe.

11. Ordered: 100 mg Solu-Medrol IM every 6 hr times 5 doses for inflammatory allergic
reaction.
Available: 500 mg Solu-Medrol/8 mL.

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After reconstituting, how many mL will you give?

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ANS:
1.6 mL

Know Want to Know

62.5 mg : 1 mL = 100 mg : x mL
62.5x = 1  100
x = 1.6 mL

Proof: 62.5  1.6 = 100

1  100 = 100

12. Ordered: Penicillin G 250,000 units IM every 12 hr for pneumonia.

Available: Penicillin G sodium 5,000,000 units per vial.

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a. How much diluent will you add?

b. How many mL will you give?

ANS:
a. 18 mL
b. 1 mL

Know Want to Know

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250x = 1250 = 250
x = 1 mL

Proof: 1  250 = 250

250  1 = 250

The 1 mL concentration is recommended as penicillin can be irritating in a concentrated form.

13. Ordered: Tazidime 150 mg IM 4 times a day for chronic bronchitis.

Available: Tazidime 500 mg.

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How many mL will you give?

ANS:
1 mL

Know Want to Know

280 mg : 1.8 mL = 150 mg : x mL
280x = 1.8  150 = 270
280x = 270 GRADESMORE.COM
x = 0.964 = 1 mL

Proof: 280  0.964 = 269.9

1.8  150 = 270

14. Ordered: Penicillin G potassium 400,000 units IM every 12 hr for an open wound.
Available: Pfizerpen 5 million units.

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a. How much diluent will you add?

b. How many mL will you give?

ANS:
a. Add 8.2 mL of diluent to make 500,000 units/mL
b. 0.8 mL

Know Want to Know

5x = 4
x = 0.8 mL

Proof: 5  0.8 = 4
14=4

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15. Ordered: Pipracil 400 mg IM 2 times a day for a wound infection.
Available: Pipracil sodium 2 g.
Directions: Add 4 mL of sterile water for injection to yield 1 g per 2.5 mL.
How many mL will you give?

ANS:
1 mL

Know Want to Know

10x = 2.5  4 = 10
x = 1 mL

Proof: 10  1 = 10
2.5  4 = 10

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16. Ordered: Solu-Medrol 30 mg IM daily times 3 days for an autoimmune inflammation.

Available: Solu-Medrol 40 mg
Directions: Press down on activator to force 1 mL of diluent into the vial.
How many mL will you give?

ANS:
0.75 mL

Know Want to Know

4x = 3
x = 0.75 mL

Proof: 1  3 = 3
4  0.75 = 3
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17. Ordered: Rocephin 500 mg IM every 4 hr for otitis media.

Available: Rocephin (ceftriaxone sodium) 2 g.

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a. How much diluent will you add?

b. How many mL will you give?

ANS:
a. Add 7.2 mL of diluent
b. 2 mL

Know Want to Know

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250 mg : 1 mL = 500 mg : x mL
250x = 500
x = 2 mL

Proof: 250  2 = 500

1  500 = 500

18. Ordered: Kefzol 75 mg IM daily for 3 days for a burn infection.

Available: Kefzol 500 mg for reconstitution.

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a. How many mL of diluent will you add?

b. How many mL will you give?

ANS:
a. Add 2 mL of diluent
b. 0.9 mL
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Know Want to Know
225 mg : 1 mL = 200 mg : x mL
225x = 200
x = 0.888 = 0.9 mL

Proof: 225  0.88 = 198

1  200 = 200

19. Ordered: Librium 75 mg IM one time only for anxiety.

Available: Librium 100 mg with 2 mL of diluent to yield 100 mg per 2 mL
How many mL will you give?

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ANS:
1.5 mL

Know Want to Know

100 mg : 2 mL = 75 mg : x mL
100x = 2  75 = 150
x = 1.5 mL

Proof: 2  75 = 150
100  1.5 = 150

20. Ordered: Velosef 200 mg IM 4 times a day for a urinary tract infection.
Available: Velosef 250 mg per vial.

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a. How many mL of diluent will you add?

b. How many mL will you give?

ANS:
a. Add 1.2 mL of sterile diluent
b. 1 mL

Know Want to Know

250 mg : 1.2 mL = 200 mg : x mL
250x = 240
x = 0.96 mL round to 1 mL

Proof: 1.2  200 = 240

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0.96  250 = 240

21. Ordered: Methicillin (Staphcillin) 1 g every 8 hr IV for a respiratory infection.

Available: Staphcillin 4 g in powdered form in the vial.
Directions: Add 5.7 mL of diluent to yield 8 mL. Further dilute in 100 mL of D5W and
infuse in 40 min.
How many mL per hr will you set the infusion device to infuse?

ANS:
150 mL per hr to infuse in 40 min

Know Want to Know

8 mL : 4 g = x mL : 1 g
4x = 8  1 = 8
x = 2 mL
Withdraw 2 mL from the vial.

Proof: 1  8 = 8
42=8

Know GRAtoDKnow
Want ESMORE.COM

4x = 10  60 = 600
x = 150 mL per hr to infuse in 40 min
Proof: 10  60 = 600
4  150 = 600

22. Ordered: Piperacillin sodium 2 g IV every 8 hr for a pelvic infection.

Available: Piperacillin 4 g vial in powdered form.
Directions: Add 7.8 mL of diluents to yield 10 mL of drug solution. Dilute the dose in 200
mL of D5W to infuse in 90 min.
How many mL per hr will you set the infusion device to infuse?

ANS:
133 mL per hr

Know Want to Know

10 mL : 4 g = x mL : 2 g
4x = 10  2 = 20
x = 5 mL
Withdraw 5 mL from the vial and inject into 200 mL D5W.
Proof: 10  2 = 20
4  5 = 20

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Know Want to Know

9x = 20  60 = 1200
x = 133.3 = 133 mL per hr to set the infusion device
Proof: 20  60 = 1200
9  133.3 = 1199.9

23. Ordered: Doxycycline (Vibramycin) 100 mg IV every 12 hr for gonorrhea.

Available: Vibramycin vial with powder to make 100 mg of medication.
Directions: Add 8 mL of diluent to make 100 mg of Vibramycin. Further dilute in 150 mL of
D5W to infuse in 50 min.
How many mL per hr will you set the IV infusion device to infuse?

ANS:
180 mL per hr

Know Want to Know

x = 3  60 = 180
x = 180 mL per hr

Proof: 1  180 = 180

3  60 = 180
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24. Ordered: Maxipime 500 mg IV every 8 hr for otitis media.
Available: Maxipime 1 g.
Directions: Add 8.7 mL of diluents to yield 10 mL of drug solution. Further dilute dose in
100 mL of D5W to infuse in 40 min.
How many mL per hr will you set the IV infusion device to infuse?

ANS:
150 mL per hr

Know Want to Know

100 x = 500
x = 5 mL
Add 5 mL of Maxipime to 100 mL of D5W.

Proof: 1  500 = 500

100  5 = 500

Know Want to Know

2 x = 5  60 = 300

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x = 150 mL per hr

Proof: 5  60 = 300
2  150 = 300

25. Ordered: Ranitidine (Zantac) 50 mg IV every 8 hr for gastric ulcers.

Available: Zantac injection (ranitidine hydrochloride) 50 mg in 50 mL 0.45% sodium
chloride.
Directions: Infuse in 20 min.
How many mL per hr will you set the IV infusion device to infuse?

ANS:
150 mL per hr

Know Want to Know

2 x = 5  60 = 300
2 x = 300
x = 150 mL per hr

Proof: 5  60 = 300
2  150 = 300

26. Ordered: Cipro 400 mg IV for a urinary tract infection. Infuse in 90 min.
Available: Cipro (ciprofloxacin) 400 mg in 40 mL of sterile 1% solution.
GRA
Directions: Further dilute in 200 DEofSM
mL ORE.COM
D5W.
a. How many drops per min will you set the IV device to infuse using a gravity tubing at 20
drops per mL?
b. How many mL per hr will you set the electronic infusion device?

ANS:
a. Use the drop rate formula: drop/time  volume = drops per min

b. 160 mL

Know Want to Know

240 mL : 90 min = x mL : 60 min
3x = 8  60 = 480
3x = 480
x = 160 mL per hr

Proof: 80  60 = 480
3  160 = 480

27. Ordered: Ticar (ticarcillin) 500 mg IM daily for 4 days for a skin infection.
Available: Ticar for IM or IV use.

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Directions: For IM use, add 2 mL of sterile water for Injection. Each 2.6 mL of solution will
contain 1 g of ticarcillin.
How many mL will you inject?

ANS:
1.3 mL

Know Want to Know

2.6 mg : 1000 mg = x mL : 500 mg
10x = 2.6  5 = 13
10x = 13
x = 1.3 mL

Proof: 2.6  5 = 13
10  1.3 = 13

28. Ordered: Oxacillin 250 mg IV every 8 hr for 4 doses for a respiratory tract infection. Infuse
in 150 mL of D5W in 50 min.
Available: Oxacillin sodium 1 g.
Directions: Add 5.7 mL sterile water for Injection. Each 1.5 mL contains 250 mg of oxacillin.
a. How many mL per hr will you set the gravity infusion set with 15 drops per min?
b. How many mL per hr will you set the electronic infusion device to infuse?

ANS:
a.
b. 180 mL GRADESMORE.COM

Know Want to Know

x = 3  60 = 180
x = 180 mL

Proof: 3  60 = 180
1  180 = 180

29. Ordered: Tagamet 200 mg IV every 12 hr for a duodenal ulcer.

Available: Tagamet multidose vial with 300 mg per 2 mL.
Directions: Dilute each dose with 50 mL of D5W to infuse in 30 min.
a. How many mL of Tagamet will you need?
b. How many mL per hr will you set the electronic infusion device to infuse?

ANS:
a. 1.33 mL

Know Want to Know

150x = 1  200 = 200

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Test Bank for Brown and Mulholland’s Drug Calculations 11th Edition by Tritak

150x = 200
x = 1.33 mL

Proof: 2  200 = 400

300  1.33 = 399

b. 100 mL

Know Want to Know

3x = 5  60 = 300
x = 100 mL per hr

Proof: 5  60 = 300
3  100 = 300

30. Ordered: 40 mEq potassium chloride in 200 mL of D5W to infuse in 90 min for potassium
depletion.
Available: 20 mL single-dose vial for IV use. Each mL contains 2 mEq of potassium
chloride.
a. How many mL of medication will you need to inject into 200 mL of D5W for infusion?
b. How many mL per hr will you set the electronic infusion device to infuse?

ANS:
a. 20 mL
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Know Want to Know
2 mEq : 1 mL = 40 mEq : x mL
2x = 40
x = 20 mL

Proof: 2  20 = 40
1  40 = 40

b. 133 mL

Know Want to Know

9x = 20  60 = 1200
9x = 1200
x = 133.33 = 133 mL per hr

Proof: 20  60 = 300
9  133.33 = 1199.9

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