University of Guyana

Access Provided by:

Pharmacotherapy: A Pathophysiologic Approach, 11e

Chapter 114: Psoriasis

SELF­ASSESSMENT QUESTIONS
1. Which of the following may precipitate new­onset psoriasis?

A . Corticosteroids

B . Azathioprine

C . β­adrenergic blocker

D . Thiazide diuretics

2. Which of the following may exacerbate preexisting psoriasis?

A . β­adrenergic blocker

B . Lithium

C . Nonsteroidal anti­inflammatory drugs

D . All of the above

3. Comorbidities associated with psoriasis include all of the following except:

A . Psoriatic arthritis

B . Crohn’s disease

C . Multiple sclerosis

D . Multiple myeloma

4. A 33­year­old white man has been diagnosed with mild plaque psoriasis. Presenting clinical signs and symptoms may include all of the following
except:

A . Hypopigmentation

B . Pruritus

C . Erythema

D . Silvery scales on lesions

5. True or false: Psoriasis is an independent risk factor for artherosclerosis.

A . True

B . False
Downloaded 2022­7­14 7:11 A Your IP is 190.80.24.243
6. True or false: Psoriasis
SELF­ASSESSMENT is usually diagnosed
QUESTIONS, Rebeccabased on aWayne
M. Law; skin biopsy.
P. Gulliver Page 1 / 3
©2022 McGraw Hill. All Rights Reserved. Terms of Use • Privacy Policy • Notice • Accessibility
A . True
D . Silvery scales on lesions
University of Guyana
5. True or false: Psoriasis is an independent risk factor for artherosclerosis. Access Provided by:

A . True

B . False

6. True or false: Psoriasis is usually diagnosed based on a skin biopsy.

A . True

B . False

7. Appropriate nonpharmacologic therapy for the above patient in Question 4 includes all of the following except:

A . Moisturizer applied ad lib

B . Oatmeal baths

C . Tanning beds

D . Stress management clinics

8. Initial pharmacologic therapy for the above patient in Question 4 should be:

A . Betamethasone dipropionate 0.05% ointment for 2 months

B . Calcipotriol 50 mcg/g cream for 2 months

C . Methotrexate 5 mg/week for 2 months

D . PUVA treatments for 2 months

9. SCAT therapy refers to:

A . Steroid + plus calcipotriol use

B . Steroid + pluscoal tar use

C . Anthralin use

D . Tazarotene use

10. Joanne is a 28­year­old woman in the first trimester of pregnancy. She has severe plaque psoriasis that did not improve when she became
pregnant. In fact, the stress of pregnancy has resulted in a flare­up of her psoriasis. An appropriate treatment for Joanne’s psoriasis would be:

A . Methotrexate

B . NB­UVB

C . Topical tazarotene

D . Acitretin

11. Moderate­to­severe psoriatic lesions in a 33­year­old white woman fail to clear with topical therapy or NB­UVB. The NB­UVB treatments were
continued and acitretin added. Appropriate counseling for this patient includes all of the following except:

A . She must be on effective birth control for the duration of acitretin therapy.

B . She must be on effective birth control for at least 2 years after discontinuing acitretin.

C . She must not donate blood.

D . She must not have more than two alcoholic drinks per day.
Downloaded 2022­7­14 7:11 A Your IP is 190.80.24.243
12. Moderate­to­severeQUESTIONS,
SELF­ASSESSMENT psoriatic lesions in a 48­year­old
Rebecca M. Law; white
Wayne man is being treated with methotrexate. Although rare, pancytopenia can occur
P. Gulliver anytime
Page 2/3
©2022 McGraw
—even after Hill.
single All Rights
doses Reserved. The
of methotrexate. Terms of Use
patient • Privacy
should Policy •about
be counseled Noticethe
• Accessibility
early signs and symptoms of pancytopenia, which include:

A . Stomatitis/oral symptoms
A . She must be on effective birth control for the duration of acitretin therapy.
University of Guyana
B . She must be on effective birth control for at least 2 years after discontinuing acitretin. Access Provided by:

C . She must not donate blood.

D . She must not have more than two alcoholic drinks per day.

12. Moderate­to­severe psoriatic lesions in a 48­year­old white man is being treated with methotrexate. Although rare, pancytopenia can occur anytime
—even after single doses of methotrexate. The patient should be counseled about the early signs and symptoms of pancytopenia, which include:

A . Stomatitis/oral symptoms

B . Fever

C . Dyspnea/cyanosis

D . All of the above

13. Initial biologic selection for a patient with moderate­to­severe psoriasis who also has active psoriatic arthritis (as recommended by both the
Canadian Psoriasis Guidelines Addendum Committee and the British Association of Dermatologists) is:

A . Alefacept

B . Adalimumab

C . Ixekizumab

D . Tofacitinib

14. The systemic treatment of choice for children with severe psoriasis is currently:

A . Acitretin

B . Methotrexate

C . Cyclosporine

D . Prednisone

15. Precautions about the use of apremilast include all of the following except:

A . Take with food

B . Do not crush, split or chew the tablet

C . Drug interaction with St. John’s wort

D . Dose reduction in renal impairment

Downloaded 2022­7­14 7:11 A Your IP is 190.80.24.243

SELF­ASSESSMENT QUESTIONS, Rebecca M. Law; Wayne P. Gulliver Page 3 / 3
©2022 McGraw Hill. All Rights Reserved. Terms of Use • Privacy Policy • Notice • Accessibility