Test Bank For Nutrition Therapy and Pathophysiology 4th Edition Nelms

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Test Bank for Nutrition Therapy and Pathophysiology 4th Edition Nelms

Test Bank for Nutrition Therapy and Pathophysiology


4th Edition Nelms

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Chapter 10 - Nutritional Genomics
1. Identify the term that refers to the sequence in mRNA that is translated into the final protein product.
a. codon
b. intron
c. exon
d. chromatin
e. genome
ANSWER: c
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:04 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CC4R
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMF-8R5S-KCMB-CE4S-
R3TW-COSU-CQJS-CRSU-1ATO-GOSU-NAUF-8YSU-Q3MN-CC4U-RP5D-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

2. Which of the following is true of the work of Gregor Mendel?


a. He was the pioneer of the Human Genome Project.
b. He described the double-helical structure of DNA.
c. He discovered the laws of genetics in the year 1865.
d. He discovered that DNA is the genetic material in living beings.
e. He proposed the concept of the genetic code.
ANSWER: c
POINTS: 1
REFERENCES: Introduction
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:06 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CC4D
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMG-GO5S-K3TT-8Y4G-
NP3T-GYSU-Y3B1-8RSU-NPBO-GOSS-ECDD-GOSU-O3BO-CIUD-RC3Z-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

3. A copy of a specific gene situated in a given locus on a chromosome is called a(n):


a. allele
b. codon
c. chromatin
d. intron
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Chapter 10 - Nutritional Genomics

e. exon
ANSWER: a
POINTS: 1
REFERENCES: Glossary
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:08 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CC3Z
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJS-8F1G-CP33-GW3G-
CCJ1-GESS-KATT-8YSU-EAUR-GOSS-NAUR-GRSU-RAMG-GBTD-QCMR-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

4. A group of gene variants that occur together is called:


a. polygenic
b. translation
c. genotype
d. phenotype
e. haplotype
ANSWER: e
POINTS: 1
REFERENCES: Glossary
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:09 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CPKN
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMD-GO4U-YQJZ-GEAU-
1QJA-GCSS-RPUF-8YSU-13TT-GOSS-NQBA-CASU-QQJI-CTUG-RP3W-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

5. The production of RNA from DNA is accomplished by what process?


a. reduction
b. expression
c. subscription
d. transcription
e. translation
ANSWER: d
POINTS: 1
REFERENCES: Glossary
QUESTION TYPE: Multiple Choice
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Chapter 10 - Nutritional Genomics

HAS VARIABLES: False


KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:10 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CPJ3
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJO-CAHD-CCBI-GBTU-
OQDB-COSU-GQDD-CESU-YCTW-GOSU-R3MN-GHSU-QCTW-G7TD-RP3U-
E7JI-YT4D-JFNN-4OTI-GO4W-NQNBEE

6. Which of the following statements is true of the work of James Watson and Francis Crick?
a. They were the pioneers of the Human Genome Project.
b. They described the double-helical structure of DNA.
c. They discovered the laws of genetics in the year 1865.
d. They discovered that DNA is the genetic material in living beings.
e. They proposed the concept of the genetic code.
ANSWER: b
POINTS: 1
REFERENCES: Introduction
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:11 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CPKG
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJA-GR4S-NPBS-GITG-
NP3U-GRSS-CA3S-CESS-GQDG-GOSU-RC3O-8YSS-ECDB-GI1D-Q3TU-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

7. Identify the disease for which human disease gene was mapped with DNA markers for the first time.
a. diabetes
b. Alzheimer's disease
c. tuberculosis
d. Huntington's disease
e. phenylketonuria
ANSWER: d
POINTS: 1
REFERENCES: Nutritional Genomics: Nutrigenetics, Nutrigenomics, and Nutritional Epigenomics
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:13 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CPKF
Copyright Cengage Learning. Powered by Cognero. Page 3
Chapter 10 - Nutritional Genomics

QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-


43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJA-GC3D-NAJ1-CE4U-
YCJI-8YSS-CQBO-8YSU-13T1-GOSU-Y3JT-GESS-CPUG-CA4S-GC5B-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

8. The interaction between drugs and an individual's genome is referred to as:


a. nutrigenetics
b. nutrigenomics
c. pharmacogenomics
d. pharmacology
e. epigenomics
ANSWER: c
POINTS: 1
REFERENCES: Nutritional Genomics: Nutrigenetics, Nutrigenomics, and Nutritional Epigenomics
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:14 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CPKD
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJ3-CPOU-RQDR-CW5S-
GCT3-GYSS-NC31-CRSU-QPMF-GOSS-EPBI-GRSS-EQJT-8R4D-GPDR-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

9. What type of cell does not contain nuclei?


a. mature red blood cells
b. nerve cells
c. heart muscle cells
d. skeletal muscle cells
e. epithelium
ANSWER: a
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:15 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CPJ1
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJS-CA4U-OA3A-C3OU-
1AUG-CRSU-1QBS-8RSU-O3UD-GOSS-EP3W-CWSS-NPTS-CEAU-EQMB-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

10. How many pairs of chromosomes comprise the human genome?


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Chapter 10 - Nutritional Genomics

a. 23
b. 22
c. 21
d. 20
e. 19
ANSWER: a
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:17 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CPJZ
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMD-CRAG-EC5R-8RHD-
KPTU-GYSS-KQJZ-8YSS-RAJ3-GOSU-RPUG-GASU-KAMN-8RAG-GAMD-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

11. Identify the sex chromosomes that are present in human males?
a. A and B
b. A and A
c. X and X
d. Y and Y
e. X and Y
ANSWER: e
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:19 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBW-CPJI
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMB-G3UD-CCDD-CW4S-
EAMD-GYSS-GPBA-CESU-CP3A-GOSU-O3UD-8YSS-NAJS-8YHG-EC5R-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

12. How many primary components are present in nucleotides?


a. 1
b. 2
c. 3
d. 4
e. 5
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Chapter 10 - Nutritional Genomics

ANSWER: c
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:20 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YOKB
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJI-GA3G-GC5G-8FTS-
NAJO-GESU-1PDD-8RSU-OP33-GOSU-OCJS-CWSU-RCTS-CTUD-EC5G-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

13. How many nitrogenous bases are present in human DNA?


a. 1
b. 2
c. 3
d. 4
e. 5
ANSWER: d
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:21 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YOJ3
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMB-GHHU-K3T3-GO4D-
EP31-GESU-NCDF-CRSU-NAJT-GOSS-CAUR-COSS-CPMF-CFTU-Q3DG-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

14. What is a series of three nucleotide bases that encodes a specific amino acid called?
a. a gene
b. a codon
c. a protein
d. an allele
e. an autosome
ANSWER: b
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
Copyright Cengage Learning. Powered by Cognero. Page 6
Chapter 10 - Nutritional Genomics

KEYWORDS: Bloom's: Remember


DATE CREATED: 4/9/2019 9:22 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YOJA
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJ3-CRHG-GATA-8RHD-
EPBI-8RSS-C3BT-8RSU-NPTO-GOSU-G3DG-COSS-CC5R-GC4D-N3DD-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

15. Which chromosome number is linked to various disease states with nutritional implications including several cancers,
type 1 diabetes, and Crohn's disease?
a. 7
b. 10
c. 12
d. 15
e. 20
ANSWER: b
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:24 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YOKR
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMD-COAS-KA5G-8FOU-
QCMF-CCSU-GAMN-8YSU-O3B3-GOSS-C3UB-CRSS-GCBO-GFUD-GCUD-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

16. What percentage of human DNA is composed of noncoding DNA?


a. 95%
b. 90%
c. 85%
d. 80%
e. 75%
ANSWER: a
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:25 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YOKD
Copyright Cengage Learning. Powered by Cognero. Page 7
Chapter 10 - Nutritional Genomics

QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-


43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMD-GEAU-GAUF-8BTS-
C3T1-8YSU-O3DB-8RSU-K3T1-GOSS-CCDN-CCSS-RPBU-GE3D-RAJS-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

17. Which nitrogenous base pairs up with adenine in human DNA?


a. guanine
b. cytosine
c. arginine
d. thymine
e. lysine
ANSWER: d
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:27 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YOJO
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJO-GW3D-1AUR-8FTS-
CATU-GWSU-OQMD-8RSU-GPJO-GOSU-GCTU-GESS-E3MB-8BTU-RQMD-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

18. Which of the following enzymes accomplishes transcription?


a. DNA polymerase
b. DNA activase
c. DNA transcriptase
d. RNA transcriptase
e. RNA polymerase
ANSWER: e
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:28 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YOJS
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJZ-GYAU-EP3I-GYHG-
KQJT-GWSS-RPBW-CESU-ECUG-GOSU-E3UF-CESU-Y3JW-GJOU-NAJ3-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

19. In humans, the inheritance of genes for blue eyes is classified as:
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Chapter 10 - Nutritional Genomics

a. X-linked dominant
b. X-linked recessive
c. autosomal recessive
d. autosomal dominant
e. Y-linked
ANSWER: c
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:30 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YOJI
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJT-CE4U-EC5F-CC5G-
KP5D-CASU-YCDN-CRSU-KAJZ-GOSU-ECBW-GRSS-RCBZ-CE5U-KP5N-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

20. What kind of hereditary disease is cystic fibrosis?


a. X-linked dominant
b. X-linked recessive
c. autosomal recessive
d. autosomal dominant
e. Y-linked
ANSWER: c
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:38 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YOTW
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJT-GH3U-OAMG-GITU-
1PT3-GASU-13MN-CESS-KPUB-GOSU-Y3BA-GASU-KPBI-8RHU-N3UD-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

21. In mammalian DNA, approximately what percentage of cytosines are methylated?


a. 19%
b. 2–5%
c. 6–8%
d. 10%
e. 12–15%
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Chapter 10 - Nutritional Genomics

ANSWER: b
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:39 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YQB3
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJU-CR4D-CPJI-GB1U-
KQBW-CWSU-YPBO-8YSS-EATA-GOSU-KQJW-GRSU-RP3T-G3OS-GC3Z-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

22. Low intake of which nutrient (particularly when combined with high alcohol intake) is associated with increased colon
cancer risk?
a. thymine
b. riboflavin
c. niacin
d. folate
e. biotin
ANSWER: d
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:40 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YQNR
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJ3-CW3D-KP3I-G71S-
CC3A-GRSS-NP5N-CESU-N3DB-GOSS-RPMD-GOSU-GCTO-GYAG-GCBO-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

23. Which nutrient in fruits and vegetables is likely the most important in reducing the risk of cancer?
a. antioxidants
b. fatty acids
c. amino acids
d. sugars
e. minerals
ANSWER: a
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Multiple Choice
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Chapter 10 - Nutritional Genomics

HAS VARIABLES: False


KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:42 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YQBT
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMF-CCAS-EAJZ-CP1D-
QCJO-CCSS-CA31-8YSU-QPUG-GOSU-CCDG-8YSU-GP3W-CPUG-KCDD-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

24. Identify a common factor that is associated with metabolic syndrome and predisposition to diabetes and cardiovascular
disease.
a. highly acidic blood
b. highly alkaline blood
c. nutritional deprivation
d. poor digestion
e. a lack of excitatory neurotransmitters
ANSWER: c
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Understand
DATE CREATED: 4/9/2019 9:43 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YQBS
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMB-CWAG-EC3U-CW5U-
N3BS-GRSS-EA3I-CESS-R3MB-GOSU-RCT1-COSS-RC5N-G7UD-OAMB-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

25. Identify the neurological disorder that occurs due to the deletion of sections of chromosomes.
a. Down syndrome
b. Turner syndrome
c. Klinefelter syndrome
d. Marfan syndrome
e. Angelman syndrome
ANSWER: e
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:44 AM
DATE MODIFIED: 4/9/2019 11:08 AM
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Chapter 10 - Nutritional Genomics

QUESTION ID: JFND-GO4N-8BBU-YQJ3


QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJA-GA3D-R3JT-CRHD-
QA5B-CASU-Q3TA-8YSU-YPDD-GOSU-EQBW-GRSS-NQMR-8Y3S-EPTA-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

26. Which gene mutation is responsible for familial hypercholesterolemia?


a. cholesterol-generating gene
b. fatty acid assimilating gene
c. HDL receptor gene
d. VLDL receptor gene
e. LDL receptor gene
ANSWER: e
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:46 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YQKR
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJW-GI1G-CQMB-CE3S-
CQMD-CESU-CP3S-8RSU-E3MF-GOSU-ECJO-GYSU-13BA-GAHD-GCTW-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

27. Consuming a diet supplemented with which of the following fatty acids reduces the inheritance of APC gene?
a. long-chain omega-3 PUFAs
b. short-chain omega-3 PUFAs
c. long-chain omega-3 MUFAs
d. short-chain omega-6 MUFAs
e. long-chain omega-6 MUFAs
ANSWER: a
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:48 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YQJ1
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJS-GTUD-O3JU-8RHU-
GPTT-CCSU-GPB3-CRSU-NP5B-GOSU-GPJO-GYSS-NP3I-8YAD-RPJI-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

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Chapter 10 - Nutritional Genomics
28. Which gene has been the target of nutritional genomics intervention to modulate CVD risk?
a. APOG gene
b. APOE gene
c. APOC gene
d. APOB gene
e. APOA gene
ANSWER: b
POINTS: 1
REFERENCES: Nutritional Genomics and the Practice of Nutrition and Dietetics
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:49 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YQJZ
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMB-GJOU-QP3Z-CR5S-
NATS-GESU-YC5N-CESS-KCDF-GOSU-NQBW-8RSS-CCTO-GAHD-EPJT-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

29. Which genotype is most likely associated with dietary and other lifestyle interventions in order to minimize CVD risk?
a. APOE E1+ genotype carriers
b. APOE E3+ genotype carriers
c. APOE E4+ genotype carriers
d. APOE E2+ genotype carriers
e. APOE E5+ genotype carriers
ANSWER: c
POINTS: 1
REFERENCES: Nutritional Genomics and the Practice of Nutrition and Dietetics
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:51 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YTKN
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMB-8BOU-1P5B-GWHU-
GAJO-CESS-NAMR-CRSU-1QBU-GOSU-OQB1-GWSU-O3JZ-GITS-CC5G-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

30. The LIPOGAIN clinical trial has shown that a diet high in saturated fat:
a. improved insulin sensitivity
b. improved glucose metabolism
c. reduced insulin synthesis
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Chapter 10 - Nutritional Genomics

d. reduced insulin secretion


e. increased DNA methylation in adipose tissues
ANSWER: e
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:52 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YTKG
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJA-CO3S-CP3A-CE4G-
ECBT-CWSS-NPTT-CESS-N3MG-GOSS-NPDF-CWSU-1P5G-GW4G-GA5D-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

31. Which of the following genes encodes the transcription factor that is involved in circadian regulation and SNPs in
humans?
a. APOE gene
b. oncogene
c. MTHFR gene
d. CLOCK gene
e. tumor suppressor gene
ANSWER: d
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:54 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YTKD
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJU-GH4U-CQB3-GCHS-
G3T3-CASS-RA3S-8YSU-O3JO-GOSS-GCBS-GASU-OC5R-CEAS-EPTT-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

32. Which initiative was developed to establish a coordinated evidence-based process for evaluating genetic tests and
translating genomic applications that are in transition from research to both clinical and public health applications?
a. The Human Genome Project
b. The Evaluation of Genomic Applications in Practice and Prevention
c. The Accountability of Clinical and Public Health Applications
d. Health Insurance Portability and Accountability Act
e. The Dietitians in Integrative and Functional Medicine
ANSWER: b

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Chapter 10 - Nutritional Genomics

POINTS: 1
REFERENCES: Nutritional Genomics and the Practice of Nutrition and Dietetics
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:55 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YTJT
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJI-CPOS-EC31-CPTD-
R3DR-CASU-NATW-CESU-Q3BT-GOSS-NCJZ-COSU-NCBO-CPTG-NCDG-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

33. The APOE gene variant that puts an individual at risk for CVD is also associated with which other disease?
a. Alzheimer's disease
b. Crohn's disease
c. cystic fibrosis
d. type 1 diabetes
e. phenylketonuria
ANSWER: a
POINTS: 1
REFERENCES: Nutritional Genomics and the Practice of Nutrition and Dietetics
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 9:57 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YT1N
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJI-8BUD-GAJT-GHAG-
R3JI-GYSU-E3MG-8YSS-EAMD-GOSS-CQB3-8YSU-YA3Z-8YHD-1QDF-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

34. Companies such as 23andMe, deCODEme, and Navigenics are conducting what type of business?
a. nutritional consulting
b. dietetic research
c. direct-to-consumer genetic testing
d. licensing nutritionists
e. assessing cardiovascular risk
ANSWER: c
POINTS: 1
REFERENCES: Nutritional Genomics and the Practice of Nutrition and Dietetics
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
Copyright Cengage Learning. Powered by Cognero. Page 15
Chapter 10 - Nutritional Genomics

DATE CREATED: 4/9/2019 9:58 AM


DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YT1F
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJ1-8YAG-EQBO-CFUD-
OA5G-8YSS-RCUB-CRSU-QA3Z-GOSU-RP5B-GHSS-CA5D-GBTG-RCTI-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

35. "Junk DNA" appears to play an important role in the:


a. stimulation of cognitive awareness
b. regulation of gene expression
c. enhancement of reproductive fitness
d. modulation of lifespan
e. stimulation of psychic phenomena
ANSWER: b
POINTS: 1
REFERENCES: Nutritional Genomics and the Practice of Nutrition and Dietetics
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:00 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YTT1
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMR-CO5G-RPBI-CPTU-
G3MG-GOSU-EPJW-8RSS-CC3I-GOSS-RQBT-GESU-C3BO-CT1D-OAJI-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

36. Mr. and Mrs. G are a married couple who are in their late 30s. They are referred by their physician to an outpatient
nutritional counseling center that specializes in genetics. Both of them have been tested for several genetic conditions as
they are at risk of developing various chronic diseases due to the familial predisposition. Mrs. G is particularly concerned
due to the history of cancer and dementia in her family, whereas obesity runs in Mr. G's family.

A registered dietitian reads the genetic report and finds that Mrs. G has a polymorphism in the methylenetetrahydrofolate
reductase gene, which is linked to the increased risk of:
a. Alzheimer's disease
b. diabetes
c. hyperlipidemia
d. cancer
e. obesity
ANSWER: d
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
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Chapter 10 - Nutritional Genomics

PREFACE NAME: Multiple


KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:01 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YTTO
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMR-GR5U-CPJS-GT1D-
QCUF-COSU-GPJ1-CRSU-KPBW-GOSS-E3T1-GHSU-K3JI-CI1U-K3TZ-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE
PREFACE GLOBAL ID: GCID-e362eb7016b6-5ad9-a164-4e9b-f930ad9d

37. Mr. and Mrs. G are a married couple who are in their late 30s. They are referred by their physician to an outpatient
nutritional counseling center that specializes in genetics. Both of them have been tested for several genetic conditions as
they are at risk of developing various chronic diseases due to the familial predisposition. Mrs. G is particularly concerned
due to the history of cancer and dementia in her family, whereas obesity runs in Mr. G's family.

Which nutrient should the registered dietician suggest Mrs. G to include in her diet via supplements to reduce the risk of
cancer?
a. niacin
b. arginine
c. vitamin A
d. biotin
e. folate
ANSWER: e
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
PREFACE NAME: Multiple
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:07 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YO3Z
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJI-CE3U-1QBO-GW4D-
G3MB-8RSU-GC5B-8YSU-CQJ3-GOSS-GA3U-GWSS-KQJ3-CTUD-EATO-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE
PREFACE GLOBAL ID: GCID-54e423c7972b-3619-47b4-1ecd-bf2a98f5

38. Mr. and Mrs. G are a married couple who are in their late 30s. They are referred by their physician to an outpatient
nutritional counseling center that specializes in genetics. Both of them have been tested for several genetic conditions as
they are at risk of developing various chronic diseases due to the familial predisposition. Mrs. G is particularly concerned
due to the history of cancer and dementia in her family, whereas obesity runs in Mr. G's family.

A diet high in which foods can potentially lower Mrs. G's risk of developing cancer?
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Chapter 10 - Nutritional Genomics

a. red beets and apples


b. strawberries and kiwis
c. cauliflower and carrots
d. celery and onions
e. watermelon and pineapple
ANSWER: c
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
PREFACE NAME: Multiple
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:09 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YTBA
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJO-G7TU-EQBW-CA5D-
YQJO-COSU-YQJT-CRSS-RCBA-GOSU-O3TT-CCSS-RAUG-CITG-RCJI-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE
PREFACE GLOBAL ID: GCID-e0ab6d60516a-ff78-f724-d018-56df97e6

39. Mr. and Mrs. G are a married couple who are in their late 30s. They are referred by their physician to an outpatient
nutritional counseling center that specializes in genetics. Both of them have been tested for several genetic conditions as
they are at risk of developing various chronic diseases due to the familial predisposition. Mrs. G is particularly concerned
due to the history of cancer and dementia in her family, whereas obesity runs in Mr. G's family.

In addition to advice on specific nutrients and foods, what should the registered dietician advise Mrs. G to avoid or limit
in order to lower her risk of this specific polymorphism?
a. physical exercise
b. alcohol
c. polyunsaturated fat
d. fructose
e. sucrose
ANSWER: b
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
PREFACE NAME: Multiple
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:11 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YTBT
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
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Chapter 10 - Nutritional Genomics

43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMG-CR4D-RCJW-CPTS-
RPJU-GHSS-E3UF-8YSU-ECJZ-GOSU-OAJU-GHSU-EPTO-GRHU-KPBI-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE
PREFACE GLOBAL ID: GCID-8a3b61d689c3-c81b-6534-f4f9-0338f38e

40. Mr. and Mrs. G are a married couple who are in their late 30s. They are referred by their physician to an outpatient
nutritional counseling center that specializes in genetics. Both of them have been tested for several genetic conditions as
they are at risk of developing various chronic diseases due to the familial predisposition. Mrs. G is particularly concerned
due to the history of cancer and dementia in her family, whereas obesity runs in Mr. G's family.

Mr. G's genetic profile shows that he has a variation in the APOE gene, which puts him at higher risk for:
a. hyperlipidemia
b. cystic fibrosis
c. prostate cancer
d. diabetes
e. Alzheimer's disease
ANSWER: a
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Multiple Choice
HAS VARIABLES: False
PREFACE NAME: Multiple
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:13 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YC1B
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJI-CRHU-NQBZ-CA5S-
NA5N-CESU-GQBO-CRSS-C3J3-GOSU-NP3U-GOSS-RCBS-G7UD-QP31-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE
PREFACE GLOBAL ID: GCID-eb8eeb9f7823-13d9-b6a4-cb56-0ccba31c

41. Production and degradation of proteins are influenced by environmental factors such as nutrition.
a. True
b. False
ANSWER: True
POINTS: 1
REFERENCES: Introduction
QUESTION TYPE: True / False
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:18 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YC3A

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Chapter 10 - Nutritional Genomics

QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-


43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMR-GO3G-GATT-CA5D-
ECJI-CWSU-1PTS-8YSU-EPB1-GOSS-EAMR-GRSS-K3JZ-GH5D-1PTA-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

42. Attention to nutritional genomics and pharmacogenomics has been escalating and this trend is likely to continue in the
coming years.
a. True
b. False
ANSWER: True
POINTS: 1
REFERENCES: Nutritional Genomics: Nutrigenetics, Nutrigenomics, and Nutritional Epigenomics
QUESTION TYPE: True / False
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:19 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YC3U
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJU-GBOU-CCJI-8YHU-
OP3Z-CESU-NAUF-CRSS-CQMF-GOSU-1A3U-COSS-KCMN-G31S-RP3S-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

43. Each gene is a linear sequence of nucleotides that are actually responsible for encoding fatty acids.
a. True
b. False
ANSWER: False
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: True / False
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:20 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YC3O
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJI-GJTS-K3DG-GEHD-
KA5G-8YSS-KCMF-8RSS-N3TZ-GOSS-CCTW-8YSU-1AJO-CW4D-1P3T-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

44. Epigenetics relates not to the genome sequence itself but to the inherited pattern of gene expression regulated by
modifications to DNA.
a. True
b. False
ANSWER: True
POINTS: 1
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Chapter 10 - Nutritional Genomics

REFERENCES: An Overview of the Structure and Function of Genetic Material


QUESTION TYPE: True / False
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:21 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YC3W
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMB-GRAD-ECJT-GPTU-
ECTA-GESS-E3TZ-CRSS-RQJW-GOSU-QCB1-GESU-CQBW-GFOS-KQBW-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

45. An individual is called homozygous for a gene when the alleles from both parents for that gene differ.
a. True
b. False
ANSWER: False
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: True / False
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:21 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YCNG
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJT-GA4D-KCMD-GOHU-
GPJI-GHSS-CPJ3-CESS-KA31-GOSS-KQMD-GHSS-CCBI-GO5S-GAT1-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

46. Like DNA methylation, histone modification is a form of epigenetic regulation.


a. True
b. False
ANSWER: True
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: True / False
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:22 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YPT1
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJI-C3TU-YPUN-GE3S-
KAT3-GYSU-QPTA-8YSU-YPJS-GOSU-EAJT-CWSU-Q3T1-COAG-N3JU-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

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Chapter 10 - Nutritional Genomics
47. Several well-defined cancers have a clearly established genetic inheritance based on mutations in a single gene.
a. True
b. False
ANSWER: True
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: True / False
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:23 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YP4B
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJA-GE5G-C3JO-CE3D-
YCMR-GOSS-C3UR-8YSU-Q3T3-GOSS-ECJO-CWSU-NPBU-GAAD-KPB1-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

48. Colon cancer risk reduction in humans via intake of cruciferous vegetables is linked to glutathione S-transferase
genotype.
a. True
b. False
ANSWER: True
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: True / False
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:24 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YP4F
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJO-GT1S-CCTA-GHAS-
CATU-GOSU-KQMF-8RSU-GCJW-GOSU-QPBA-8YSU-OAJO-GF1G-G3JW-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

49. The recommendation of one diet intervention in response to one polymorphism is likely too complicated.
a. True
b. False
ANSWER: False
POINTS: 1
REFERENCES: Nutritional Genomics and the Practice of Nutrition and Dietetics
QUESTION TYPE: True / False
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:26 AM

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Chapter 10 - Nutritional Genomics

DATE MODIFIED: 4/9/2019 11:08 AM


QUESTION ID: JFND-GO4N-8BBU-YP3U
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJA-GYAD-KPJ3-GEHD-
Y3DN-GWSU-RATI-CRSS-NATA-GOSS-GPT1-CESS-C3TS-CFUG-NPUD-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

50. The assembly of a polypeptide chain based on the sequence of mRNA is known as translation.
a. True
b. False
ANSWER: True
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: True / False
HAS VARIABLES: False
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:26 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YP3I
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJT-CW5U-G3JO-CAHD-
YA5N-CWSS-E3MF-CRSS-KAJ3-GOSU-RPB3-8YSU-G3T1-CR3S-EAJU-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

51. _______________ is a technology used to measure expression of thousands of genes simultaneously.


ANSWER: Microarray
POINTS: 1
REFERENCES: Glossary
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:27 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YPBA
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJT-CAAD-QC3U-CAHU-
CC5G-8YSU-RP3Z-8YSS-RAJO-GOSS-KC3A-CRSS-NCJT-GPUG-EA3A-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

52. _______________ is a small noncoding RNA molecule involved in the regulation of gene expression.
ANSWER: MicroRNA; miRNA
POINTS: 1
REFERENCES: Introduction
QUESTION TYPE: Completion
HAS VARIABLES: False
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Chapter 10 - Nutritional Genomics

STUDENT ENTRY MODE: Basic


KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:28 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YPNF
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJO-GO3G-EP31-GCAU-
CA3I-CCSU-1QJ1-8RSU-C3T3-GOSU-RCMN-GHSU-RCDG-8RAD-YPJS-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

53. One of the hottest areas of debate regarding the interplay between ethics and genetics has to do with direct-to-
consumer marketing of _______________.
ANSWER: genetic tests
POINTS: 1
REFERENCES: Nutritional Genomics: Nutrigenetics, Nutrigenomics, and Nutritional Epigenomics
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:29 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YPB1
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJ1-GEAU-RCMD-GP1U-
R3JI-GASS-E3TU-8YSS-NPUD-GOSU-QPMF-CESS-R3JS-GW4U-YCDD-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

54. _______________ was identified as the blueprint of life in the year 1944.
ANSWER: Deoxyribonucleic acid; DNA
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:30 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YPBT
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMB-GO3S-ECBS-GRHU-
KCBI-COSU-OPBI-CRSS-GP5N-GOSS-NA5R-GCSS-CCDR-GF1U-ECTS-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

55. The nitrogenous bases include adenine and _______________ (both purines) as well as thymine and
_______________.
ANSWER: guanine; cytosine
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Chapter 10 - Nutritional Genomics

POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:38 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YPKD
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJI-G3UD-C3JO-GWAS-
CCTT-CASU-1CTS-CRSU-QAJW-GOSS-CCBO-COSU-1ATZ-GWHU-KCBU-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

56. DNA contains noncoding regulatory sequences called _______________ to which molecules can bind in order to
signal unwinding of a specific region of DNA for creation of a needed protein.
ANSWER: promoter regions
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:39 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YPJ1
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMR-CPTD-EP3U-CFTU-
ECMR-8YSU-EPMN-8YSU-CC3T-GOSU-GPT3-8RSU-O3TS-GFTD-RCDR-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

57. The coding strand of DNA that serves as the template for mRNA synthesis is known as the _______________ strand.
ANSWER: sense
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:40 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-YPJO
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJU-CWAU-O3UG-CRAU-
RPTA-8RSS-GCJ3-8YSU-1PTW-GOSU-YAJ1-GCSS-CATO-GF1U-CCDF-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE
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Chapter 10 - Nutritional Genomics

58. The complement of RNA transcripts produced when genes are "expressed" is referred to as the _______________.
ANSWER: transcriptome
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:43 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOKN
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJU-GO3U-YA5F-CC5D-
GQJU-GCSU-1C3U-8YSU-1PTS-GOSU-Y3JO-CCSU-QCDD-8R3S-GPDD-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

59. _______________ in nucleotides can both promote or suppress the production and function of a protein.
ANSWER: Polymorphisms; Variations
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:44 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOKG
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJW-GF1U-KQBT-GJTS-
KCJZ-GOSU-QQMF-CESU-RC5B-GOSU-RCDG-CCSS-E3JT-CRHD-QATU-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

60. As opposed to monogenic diseases, diseases such as obesity, diabetes, cancer, and cardiovascular disease are
_______________.
ANSWER: polygenic
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:45 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOKF

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Chapter 10 - Nutritional Genomics

QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-


43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJ3-GBTD-YQMN-GF1U-
CQBO-GASS-G3DB-CRSS-NATO-GOSS-K3UD-GASU-KPBZ-CFOS-KAT1-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

61. It is predicted that there are a few hundred _______________ genes in humans.
ANSWER: imprinted
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:46 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOJU
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMG-GIOU-GCBA-GA3U-
GC3O-CRSU-OP3U-CESU-RPBO-GOSU-E3JS-8RSU-QPTA-GAAU-KC5D-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

62. Environmental factors play a critical role in regulating gene _______________.


ANSWER: expression
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:47 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOJT
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMN-C3UD-C3BA-CTTS-
KQDN-8RSU-OA33-CESS-KATZ-GOSU-YP3W-CESU-QC3S-CE5G-K3BO-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

63. Epidemiological research has linked processed meats to increased risk of _______________ cancer.
ANSWER: colon
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:48 AM
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Chapter 10 - Nutritional Genomics

DATE MODIFIED: 4/9/2019 11:08 AM


QUESTION ID: JFND-GO4N-8BBU-NOJZ
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMR-CC4U-Q3UF-GFTU-
OP3I-GCSU-13UB-CRSS-RPUF-GOSS-KQJI-CESU-QPUB-G7OU-NAUG-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

64. Cancer can result from genome-wide _______________ due to inappropriate gene activation and chromosomal
instability.
ANSWER: hypomethylation
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:48 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOJS
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJA-GOAD-GPJS-C3TS-
RCBA-CWSU-K3JW-CESS-CQB3-GOSS-RP5B-8RSS-CPDB-8Y5U-YCT1-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

65. The interaction of folate status and MTHFR genotype with _______________ appears to be of critical importance.
ANSWER: alcohol
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:49 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOJW
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJ3-GFTG-RP5R-GOAS-
EA3O-8YSU-YAJI-CRSU-OATU-GOSU-1CJZ-CESS-E3J3-GWHU-OAUB-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

66. Dietary modification such as avoidance of phenylalanine in the diet is effective for an autosomal recessive trait called
_______________.
ANSWER: phenylketonuria
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Completion
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Chapter 10 - Nutritional Genomics

HAS VARIABLES: False


STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:50 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NO1N
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJA-CITU-1CJT-GWHS-
GPBO-GCSU-E3J3-8YSU-EAJT-GOSS-GPDN-CASU-NPUG-CP1U-E3JO-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

67. _______________ have allowed for testing hundreds of thousands of SNPs throughout the genome to identify
associations with specific traits.
ANSWER: Genome-wide association studies; GWAS
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:51 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NO1B
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJS-CC4U-QPDN-CRHU-
OPBA-8YSS-CQDG-8YSS-KQJS-GOSU-1P5D-GYSU-O3JT-8R3G-KC3Z-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

68. Since oxidative DNA damage is thought to play a role in carcinogenesis, adequacy of _______________ is suggested
to be anticarcinogenic.
ANSWER: antioxidants
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:52 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOT3
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJT-CEAU-OAUB-GTUD-
1CJ3-CRSU-13TT-CESU-YCBA-GOSS-GPJI-GCSS-K3BT-GEHG-CCTW-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

69. The Evaluation of Genomic Applications in Practice and Prevention initiative was developed by the Office of Public
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Chapter 10 - Nutritional Genomics
Health Genomics of the _______________.
ANSWER: Centers for Disease Control and Prevention
POINTS: 1
REFERENCES: Nutritional Genomics and the Practice of Nutrition and Dietetics
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:53 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NO1G
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJT-CC5U-Y3TZ-GYAS-
EP5N-CESU-NCUR-CRSU-GPDG-GOSS-RPUD-GOSU-13BZ-G71S-N3MD-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

70. In addition to the genome sequence, the role of _______________, the microbiome, and modulation of gene
expression by dietary factors must also be considered in the overall scope of genome–nutrient interactions.
ANSWER: epigenetics
POINTS: 1
REFERENCES: Nutritional Genomics and the Practice of Nutrition and Dietetics
QUESTION TYPE: Completion
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 10:58 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOTU
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJO-CT1S-CA3O-C3UD-
NPUG-GASU-RC5N-8YSU-C3JZ-GOSU-E3TI-GASS-KC3I-CJTD-K3UF-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

71. Briefly outline the ethical challenges in nutritional genomics research.


ANSWER: This area includes issues related to protection of human research participants (i.e., privacy
and identifiability of genetic information), recruitment of diverse participants in genomics
research, community engagement, and other related areas.
POINTS: 1
REFERENCES: Nutritional Genomics: Nutrigenetics, Nutrigenomics, and Nutritional Epigenomics
QUESTION TYPE: Subjective Short Answer
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Understand
DATE CREATED: 4/9/2019 10:59 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOTO
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Chapter 10 - Nutritional Genomics

QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-


43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMD-GAAD-EQMG-GP1U-
RCUD-CRSU-RPJ3-CESU-QQDR-GOSU-K3T1-GCSS-R3B3-GC5D-CP3U-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

72. Discuss the sex chromosomes.


ANSWER: Of the 23 pairs of chromosomes, 22 are autosomes and one pair is comprised of the sex
chromosomes. Males have one X and one Y chromosome, while females have two X
chromosomes, so the gender of offspring is determined by the male parent.
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Subjective Short Answer
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 11:00 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NOTZ
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJI-GBTD-OAUD-GIOU-
GPDB-GHSU-Q3DB-8YSS-NQDF-GOSU-NQJU-8RSS-EPUF-8F1U-YCJ1-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

73. List the classifications of inherited genes.


ANSWER: Inherited genes can be classified as autosomal dominant, autosomal recessive, X-linked
dominant, X-linked recessive, or Y-linked.
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Subjective Short Answer
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 11:01 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NQNN
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJ3-8YAD-GQBW-CA3D-
YC5R-GASU-1QJA-8YSU-NPTU-GOSS-GCBW-CESU-Q3MF-8YHS-RCB1-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

74. Describe familial hypercholesterolemia.


ANSWER: Familial hypercholesterolemia is an autosomal dominant disorder characterized by absence
or mutation of LDL receptors leading to severely elevated LDL cholesterol levels and risk
of early myocardial infarction and death.
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Subjective Short Answer
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Chapter 10 - Nutritional Genomics

HAS VARIABLES: False


STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 11:01 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NQNB
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJS-CA4G-EAJS-GP1G-
GP3T-CCSU-GPBU-8YSS-GQJZ-GOSU-NA3O-COSS-KC3O-GE3U-YPUG-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

75. Briefly discuss the connection between folate intake and cancer risk.
ANSWER: Low intakes of folate have a long association with cancer risk, including cancer of the
colon, and this risk appears to escalate in the presence of high alcohol intake. It is also
possible that high folate intake and consequent hypermethylation of tumor suppressors
could increase cancer risk.
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Subjective Short Answer
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Understand
DATE CREATED: 4/9/2019 11:02 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NQNG
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMR-GJ1G-EAMB-CW5U-
Q3DD-GRSU-CPBS-8YSU-EQMN-GOSS-RP5N-GWSS-GAUF-GW5S-EATA-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

76. Outline the differences between nutrigenetics and nutrigenomics.


ANSWER: Nutrigenetics is the interaction between an individual's genetic profile (i.e., genotypes of
specific genes and the function of proteins encoded by those genes) with nutrients and
other bioactive food components. In contrast, nutrigenomics is the study of mechanisms by
which nutrients and other food-derived bioactive substances interact with the genome to
influence gene expression.
POINTS: 1
REFERENCES: Glossary
QUESTION TYPE: Subjective Short Answer
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Understand
DATE CREATED: 4/9/2019 11:03 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NQNR
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
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43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMMG-CO3S-EPTT-GY4D-
EPDB-GYSU-YP33-8YSS-RC31-GOSU-QA3W-CASU-NCBO-CE5U-YCDF-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

77. Discuss what happens once transcription is complete.


ANSWER: Once transcription is complete, mRNA undergoes post-transcriptional processing.
Enzymes in the nucleus excise segments of the mRNA known as introns, while leaving the
segments known as exons. Thus, only exons are ultimately translated into the final protein
product. While DNA remains in the nucleus, the messenger RNA carries the code out of
the nucleus into the cytosol, where ribosomes on the rough endoplasmic reticulum are
prepared for protein assembly. The complement of RNA transcripts produced when genes
are "expressed" is referred to as the transcriptome.
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Subjective Short Answer
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Understand
DATE CREATED: 4/9/2019 11:04 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NQBU
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJI-CO5G-NP31-GR5D-
QPB1-GHSS-NQDD-8YSS-ECB3-GOSU-NCTU-GRSS-EP33-GRAU-NC5F-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

78. Give examples of an autosomal recessive trait and an autosomal dominant disorder.
ANSWER: An example of an autosomal recessive trait is phenylketonuria, in which affected
individuals inherit one mutated copy of the phenylalanine hydroxylase gene from each
parent (homozygous). The resulting inability to convert phenylalanine to tyrosine requires
lifelong phenylalanine restriction to prevent mental retardation. Familial
hypercholesterolemia is an example of an autosomal dominant disorder and is
characterized by absence or mutation of LDL receptors leading to severely elevated LDL
cholesterol levels and risk of early myocardial infarction and death.
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Subjective Short Answer
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Remember
DATE CREATED: 4/9/2019 11:05 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NQBT
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJS-8B1D-CCJU-8F1D-
QCTT-CRSU-QC3T-8RSS-RQJI-GOSU-ECJA-8RSU-YPUB-GC4U-ECBS-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

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Test Bank for Nutrition Therapy and Pathophysiology 4th Edition Nelms

Chapter 10 - Nutritional Genomics


79. Discuss the epigenetic regulation of gene expression.
ANSWER: Gene expression is regulated in many ways, including DNA methylation; histone
methylation, acetylation, or phosphorylation; and transcription factors. More recently,
noncoding RNAs, such as the miRNAs, have been identified as playing a regulatory role as
well. All of these regulatory mechanisms can be influenced by early programming in
response to nutrition and other environmental factors in fetal life or infancy as well as
throughout the lifespan.
POINTS: 1
REFERENCES: An Overview of the Structure and Function of Genetic Material
QUESTION TYPE: Subjective Short Answer
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Understand
DATE CREATED: 4/9/2019 11:06 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NQBZ
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJO-CAHU-RA5B-G7UG-
N3B3-GOSS-NCUR-CESU-CA3S-GOSU-NAUN-GASS-KQJ3-CCAU-CP5F-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

80. Discuss the link between genetics and obesity.


ANSWER: Obesity has a clear link to genetics, demonstrated by numerous studies showing that
obesity does persist in families even where food intake and physical activity patterns
differ. However, the escalating obesity epidemic in recent decades supports the idea that,
while susceptibility to obesity is genetically and epigenetically determined, the
development of obesity itself is the result of a susceptible genome in the presence of a
conducive environment. In other words, placing susceptible individuals in an obesogenic
environment—one characterized by plentiful energy-dense, high-fat foods and
technological advances requiring little in the way of physical activity—results in obesity.
POINTS: 1
REFERENCES: Nutritional Genomics in Disease
QUESTION TYPE: Subjective Short Answer
HAS VARIABLES: False
STUDENT ENTRY MODE: Basic
KEYWORDS: Bloom's: Analyze
DATE CREATED: 4/9/2019 11:07 AM
DATE MODIFIED: 4/9/2019 11:08 AM
QUESTION ID: JFND-GO4N-8BBU-NQBS
QUESTION GLOBAL ID: GCID-E7BW-1TBP-GJUD-1QDB-CA5U-E3BZ-CE5N-43JU-C3TN-4P5D-GR4N-
43JO-CITN-4C5B-GE5D-OP33-CTDI-GWN8-EPRW-EMJW-8Y4U-CP31-8FUG-
RQB3-CASU-C3BO-8YSS-KQJO-GOSU-GPDB-CRSS-G3UR-GAAS-CA3Z-E7JI-
YT4D-JFNN-4OTI-GO4W-NQNBEE

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