2172. Tuberculosis and HIV Coinfection in Hospitalized Colombian adherent. 85.

adherent. 85.2% of patients had CD4 counts less than 200 CD4 cells/µL and 68.8 had
Patients HIV viral loads greater than 100,000 copies/mL. Within the past year, 8.5% of patients
Maria Alvarez, Resident1; Juan Pablo Villa, Infectious Disease Resident2; Carlos had had tuberculin testing; 4 of the tuberculin tests were positive and only 1 was treated.
Agudelo Restrepo, MD, MSc3; Alicia Hidron, MD, DTMH4; Lina Echeverri, MD5; 41.8% of patients had previously had TB, and of these only 13% were on HAART. Types
Jaime Mauricio Ramirez, MD6; Adriana Ocampo, MD7; Glenys Porras, MD8; of compromise with tuberculosis are depicted in the table. The main concomitant oppor-
Ivan Trompa, MD9; Carlos Restrepo, MD, MSc10; Laura Restrepo, Medical Student1; tunistic infections were candidiasis (14.1%), histoplasmosis (11.7%) and toxoplasmosis
Alejandro Eusse, Medical Student1; 1Universidad Pontificia Bolivariana, Medellín, (7.8%). Antituberculous medication toxicity occurred in 12.5%; 3.9% needed change
Colombia; 2Internal Medicine, Universidad Pontificia Bolivariana, Medellín, in treatment. The mean hospital stay was 23.2 (SD +14.7) days, 14.8% of patients required
Colombia; 3Infectious Diseases, Clínica Universitaria Bolivariana Universidad admission to the intensive care unit and 10.2% readmission, mortality was 5.5%.
Pontificia Bolivariana, Medellín, Colombia; 4Medicine, Universidad Pontificia
Bolivariana, Medellín, Colombia; 5Hospital San Vicente Fundación, Medellín, Table: Types of Compromise With Tuberculosis
Colombia; 6Hospital Universitario San Vicente Fundación, Medellín, Colombia;
7
Centros Especializados San Vicente Fundación, Rionegro, Colombia; 8Hospital Type of tuberculosis N = 128 n (%)
General de Medellín, Medellín, Colombia; 9IPS Universitaria, Clínica León XIII,
Medellín, Colombia; 10Clínica Universitaria Pontificia Bolivariana, Medellín, Only pulmonary TB 44 (34.4)
Extrapulmonary + pulmonary 62 (48.4)
Colombia
Extrapulmonary (without pulmonary) 22 (17.2)
Session: 240. HIV: Other Opportunistic Conditions Nodal 8 (6.3)
Saturday, October 29, 2016: 12:30 PM Meningeal 3 (2.3)
Disseminated 3 (2.3)
Background. Patients with HIV have between 20 and 37 times greater risk of tu- Others 6 (4.7)

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berculosis infection. Concomitant treatment of latent tuberculosis (TB) infection with
early highly active antiretroviral therapy (HAART) in high prevalence countries helped
decrease HIV-associated infections by 44% and mortality decreased by 35%.
Methods. Descriptive study including patients admitted with TB/HIV at 6 hospi-
tals in Medellín, Colombia, where data were prospectively collected for 1 year.
Results. In all, 128 HIV/TB infected patients were admitted: 79.7% were male with a
mean age of 38.4 years (standard deviation 11.3). De novo HIV diagnosis was made in
28.9%. At the time of admission, 47% of patients were on HAART and 35% were
Others: bone, peritoneal, soft tissues, intestinal, pleura
Conclusion. Sustainable strategies in order to implement and maintain LTBI diag-
nosis and treatment programs in HIV/TB coinfected patients, as well as programs en-
forcing the use and adherence to HAART are needed in developing countries where
the burden of TB is high
Disclosures. All authors: No reported disclosures.

Poster Abstracts • OFID 2016:3 (Suppl 1) • S599