Emerys Elements of Medical Genetics 14th Edition Turnpenny Test Bank

Emerys Elements of Medical Genetics 14th Edition

Turnpenny Test Bank

To download the complete and accurate content document, go to:

https://testbankbell.com/download/emerys-elements-of-medical-genetics-14th-edition-
turnpenny-test-bank/

Visit TestBankBell.com to get complete for all chapters

Turnpenny: Emery’s Elements of Medical Genetics, 14th Edition
Chapter 10: Hemoglobin and the Hemoglobinopathies

Test Bank

Multiple Choice

1. The HbA form of hemoglobin consists of which globin chains?

A. 1 , 1 
B. 2 , 2 
C.  
D. 2 , 2 
E. 1 , 1 
ANS: B

2. Which of the following statements is true regarding the  and  globin chains?

A. They are identical at the nucleotide and amino acid sequence level
B. They differ at the nucleotide level but are identical at the amino acid level
C.  pairs only with 1, and  pairs only with 
D.  is expressed in the fetus, and  is expressed after birth
E.  is a pseudogene of 
ANS: B

3. This region regulates the switching of the -like globin chains during development.

A. Locus control region

B. Master globin regulator
C. Imprinting control region
D. Globin switch
E. Immediate early region
ANS: A

4. Which of the following statements is true of the sickle cell trait-associated form of
hemoglobin, Hb S?

A. It is characterized by a relative deficiency of  chains versus  chains

B. It has increased oxygen binding affinity relative to Hb A
C. It is less soluble than Hb A
D. It is dominant to Hb A
E. Therapeutic approaches have been highly successful in alleviating phenotypes
associated with Hb S

Copyright © 2012, 2007, 2005 by Churchill Livingstone, an imprint of Elsevier Ltd.

Emerys Elements of Medical Genetics 14th Edition Turnpenny Test Bank

Test Bank 10-2

ANS: C

5. The complete absence of  globin production gives rise to which phenotype?

A. Sickle cell disease

B. Hb H disease
C. -thalassemia
D. Hydrops fetalis
E. Normal adult hemoglobin production
ANS: D

Copyright © 2012, 2007, 2005 by Churchill Livingstone, an imprint of Elsevier Ltd.

Visit TestBankBell.com to get complete for all chapters