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Records identified through Additional records identified

database searching (N=498) throught other sources (n=20)


Pubmed (n=138)
Cochrane (n=228)
Science Direct (n=132)
Medline (n=100)

Records after duplicated removed


(n=618)

Records screened (n=121)

Full-text articles
assessed for eligibility (n=71)

Studies included in qualitative synthesis


(n =7)

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