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    Latihan MDL

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    Muhammad Iqbal
    This document provides guidelines for determining detection limits for AKL analysis. It details the steps to calculate the method detection limit (MDL), limit of quantitation (LOQ), and identification limit (IDL) based on spike recoveries, standard deviations, and Horwitz coefficients. The analyst must test for high and low checks, signal to noise ratios, spike recoveries between 85-115%, and ensure regulatory requirements are met. If the MDL is greater than the IDL, the average should be removed from calculations. The conclusion will either reject or accept the detection limits based on these criteria.

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    Latihan MDL

    Uploaded by

    Muhammad Iqbal
    6 views2 pages
    This document provides guidelines for determining detection limits for AKL analysis. It details the steps to calculate the method detection limit (MDL), limit of quantitation (LOQ), and identification limit (IDL) based on spike recoveries, standard deviations, and Horwitz coefficients. The analyst must test for high and low checks, signal to noise ratios, spike recoveries between 85-115%, and ensure regulatory requirements are met. If the MDL is greater than the IDL, the average should be removed from calculations. The conclusion will either reject or accept the detection limits based on these criteria.

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    This document provides guidelines for determining detection limits for AKL analysis. It details the steps to calculate the method detection limit (MDL), limit of quantitation (LOQ), and identification limit (IDL) based on spike recoveries, standard deviations, and Horwitz coefficients. The analyst must test for high and low checks, signal to noise ratios, spike recoveries between 85-115%, and ensure regulatory requirements are met. If the MDL is greater than the IDL, the average should be removed from calculations. The conclusion will either reject or accept the detection limits based on these criteria.

    Copyright:

    © All Rights Reserved
    Download as XLSX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as xlsx, pdf, or txt
    6 views2 pages

    Latihan MDL

    Uploaded by

    Muhammad Iqbal
    This document provides guidelines for determining detection limits for AKL analysis. It details the steps to calculate the method detection limit (MDL), limit of quantitation (LOQ), and identification limit (IDL) based on spike recoveries, standard deviations, and Horwitz coefficients. The analyst must test for high and low checks, signal to noise ratios, spike recoveries between 85-115%, and ensure regulatory requirements are met. If the MDL is greater than the IDL, the average should be removed from calculations. The conclusion will either reject or accept the detection limits based on these criteria.

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    of 2

    Form AKL

    PANDUAN PENENTUAN DETEKSI LIMIT AKL

    Analis Logam
    Parameter
    Methode
    Tanggal Selesai
    Tanggal Mulai

    Spike = 0.10
    n = 10 Blk Hasil n=7 Spike Hasil %R
    1 Blk 1 1 Spike 1
    2 Blk 2 2 Spike 2
    3 Blk 3 3 Spike 3
    4 Blk 4 4 Spike 4
    5 Blk 5 5 Spike 5
    6 Blk 6 6 Spike 6
    7 Blk 7 7 Spike 7
    8 Blk 8 Rerata
    9 Blk 9 SD
    10 Blk 10 MDL = 3.14 X SD
    Rata-rata = MDL ,=
    SD = LOQ =
    IDL = (3 x SD) + Rata-rata CVHorwitz 21-0.5LogC C Fraksi =
    IDL =
    MDL > IDL Stop hilangkan rerata
    Tentukan Spike/ est. spike
    fpengali ( 3 - 5 ) 0.67 CVHorwitz
    Spike = dilakukan ppm

    Pengujian MDL Rumus Hasil Keterangan


    1. HC ( HighCheck) MDL x 10 = > spike
    2. LC ( LowCheck) MDL = < Spike
    3. S/N ( Sinyal/ Noise ) Rerata/ SD, ( 2.5 - 10 )
    4. Recovery ( 85-115)% Rerata/ Spike
    5. Requirement Regulasi>MDL>IDL 50.00
    6. %RSD %RSD < 0,67 CVHorwitz
    Lihat Regulasi terkecil terhadap parameter uji
    Analyzed by, Checked by

    0 Sri Nugroho
    Analist Chemist
    Simpulan
    Ditolak Diterima

    Lampiran : Penentuan Deteksi Limit


    Analyst : 0 Kurva Kalibrasi Cd

    Conc Intensitas 600.00


    0.000 22.16
    500.00
    0.005 30.25
    f(x) = 451.169532664546 x + 25.7021589919256
    0.010 36.17 400.00 R² = 0.996822474418479
    0.020 47.55
    0.050 52.85 300.00
    0.100 61.35
    200.00
    0.200 100.35
    0.500 250.14 100.00
    1.000 480.95
    0.00
    Correl 0.99841
    0.000 0.200 0.400 0.600 0.800 1.000 1.200
    200.00

    100.00

    0.00
    0.000 0.200 0.400 0.600 0.800 1.000 1.200
    Slope 451.16953
    intercept 25.70216

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