RISK FACTORS OF PRETERM BIRTHS IN UMBU

RARA MEHA GENERAL HOSPITAL:

A CASE CONTROL STUDY
STASYA ZEPHORA1, ERICK KRISTIANTO ADITYATAMA1, STEVIA ARIELLA PASANDE1, TANTRI
ERIKA2, SONDANG H. PANJAITAN3
1GENERAL PRACTITIONER, MD, UMBU RARA MEHA GENERAL HOSPITAL, WAINGAPU OF EAST

SUMBA REGENCY, EAST NUSA TENGGARA

=DEPARTMENT OF PEDIATRICS , MD, FACULTY OF MEDICINE, DIPONEGORO UNIVERSITY, DR.

KARIADI HOSPITAL, SEMARANG

3PEDIATRICIAN, MD, UMBU RARA MEHA GENERAL HOSPITAL, WAINGAPU OF EAST SUMBA

REGENCY, EAST NUSA TENGGARA

• Prematurity is the first leading cause of neonatal mortality.

• Indonesia has the incidence of prematurity 35% and has a major role of
verview neonatal mortality.
• East Nusa Tenggara has high rate of neonatal death (26/1,000 live births)
compared to the national rate of 20/1,000 live births

• The purpose of this study is to acknowledge the most significant

risk factor that is associated with preterm births ntroduction
• The research population are all babies with risk factors who were referred to
Umbu Rara Meha General Hospital on November 2017 to April 2018.
• Research is an analytic study with case control design and retrospective
ethods studies of 60 samples.
• Research instrument used is Medical Record. Data were analyzed by chi-
square test for bivariate and logistic regression for multivariate.

• The results showed that there was a significant association between anemia
(p: 0,001; OR: 9.000; 95% CI: 2.239-36.171) and Pre-labor Rupture of Membrane
(p: 0,027; OR: 3.500; 95% CI: 1.112-11.017) of preterm birth.
• We continued to analyze both of risk factors with logistic regression showing
anemia was the only significant factor in this research (p=0,002; OR: 9.585 ; CI
95% 2.239 – 36.171).
• Preeclampsia, ANC under standard, Gestational Hypertension, Pulmonal esults
Tuberculosis, High risk age of pregnancy, and Gemelli showed no significant
relationship with the occurrence of premature labor.

Variables OR CI 95% p
Preeclampsia 0.444 0.100 – 1.974 0.236
ANC Understandard 0.875 0.318 – 2.410 0.500
Gestational Hypertension 0.310 0.030 – 3.168 0.306
Gemelli 2.154 0.363 – 12.764 0.335
Anemia 9.000 2.239 – 36.171 0.001
High Risk Age of Pregnancy 1.000 0.282 – 3.544 0.626
Pulmonal Tuberculosis 1.000 0.060 – 16.763 0.754
Prelabor Rupture of Membrane 3.500 1.112 – 11.017 0.027

• Anemia in pregnancy is the only risk factor on the incidence of preterm birth in
Umbu Rara Meha General Hospital.
onclusion • ANC during pregnancy is recommended due to anemia screening and its
interventions to prevent preterm birth and decrease neonatal mortality.

Keyword: Preterm birth, Anemia in Pregnancy, Neonatal Mortality, Prelabor Rupture of Membrane
1. M.S. Kosim, A. Yunanto, R. Dewi, G.I. Sarosa, A. Usman. 2012. Buku Ajar Neonatologi IDAI.
2. T.L. Gomella. 2013. 7th Edition Neonatology: Management, Procedures, On Call Problems, Diseases, Drugs. New York, NY: Lange Medical Books/McGraw-Hill
3. Departemen Kesehatan Republik Indonesia. Riset Kesehatan Dasar (Riskesdas). 2012. Jakarta: Badan Penelitian dan Pengembangan Kesehatan
4. Arvin BK, Nelson Ilmu Kesehatan Anak. Prof. DR.dr. A. Samik Wahab Sp.A (K). 2012. Jakarta: EGC
5. Pediatrics AAP. Neonatal Morbidity and 1-Year Survival of Extremely Preterm Infants. Pediatrics. 2017.
6. Farstad T, Bratlid D, Med S, Markestad T; Norwegian Extreme Prematurity Study Group Bronchopulmonary dysplasia—prevalence, severity and predictive factors in a
national cohort of extremely premature infants. 2011. Acta Paediatr.
7. Dahlan, Sopiyudin ,2014. Statistik Untuk Kedokteran Dan Kesehatan Edisi 6. Jakarta, Salmba Medika. Sudjana (2009)