Development Formulation

Clear shampoo with APISCALP™ (*) SED1409166K

(*) Patent N° FR 3 034 314 - WO 2016/157073

This clear shampoo with Apiscalp™ is formulated to relieve all irritating and visible signs of dandruff.
Apiscalp™ is fighting against itching, dryness and hyperseborrhea of irritated scalp. Crodateric™ CAB
30 is a mild surfactant with gentle cleansing properties which, combined with an anionic surfactant,
confers mild detergency, excellent foaming and lathering characteristics to the formula. Crothix™ Liquid
increases viscosity in synergy with other detergents. This gentle shampoo with Apiscalp™ controls and
helps prevent the recurrence of scalp itching, irritation, redness to leave hair healthy.

Ingredient/INCI Name Functionality % w/w

Part A
Water Deionised (Aqua) - To 100
Citric Acid pH Adjuster 0.12
Sodium Citrate pH Adjuster 1.20
Part B
PEG-60 Hyrogenated Castor Oil Solubiliser 4.00
APISCALP™(Caprylic/Capric Triglyceride (and) Apium Graveolens Scalp care active 2.00
(Celery) Seed Extract)2
Part C
Empicol® ESB3 (Sodium Laureth Sulfate)3 Surfactant 30.00
Crodateric™ CAB 30 (Aqua (and) Cocamidopropyl Betaine)1 Surfactant 10.00
Phenoxyethanol Preservative 0.80
Part D
Waterlily Sap4 Fragrance 0.10
Crothix™ Liquid (PEG-150 Pentaerythrityl Tetrastearate (and) Surfactant thickener 2.50
Aqua (and) PEG-6 Caprylic/Capric Glycerides)1
Part E
Water Deionised (Aqua) - 2.00
Sodium Hydroxide 30% pH Adjuster 0.20

Suppliers: 1: Croda 2: Sederma 3: Huntsman 4: Expressions Parfumées

Procedure:
Weigh and mix Part A. Heat Part A to 55°C in bain-marie. Weigh and heat Part B to 55°C in bain-marie. Add Part B to
Part A with round helix stirring. Add ingredients of Part C one after one into Part A+B with round helix stirring. Add Part
D below 35°C with round helix stirring, mix well. Adjust pH with Part E to pH = 5.90 ± 0.10.

Appearance: Clear colourless fluid gel; pH: 5.90 ± 0.5; Viscosity: 1.000 cps ± 10% Sp.93, 2.5rpm, 1 min, 25°C,
Brookfield DV-I Prime
Stability: 3 months at 4°C, 25°C, 40°C and 1 month at 50°C
Centrifuge 10min @ 3000rpm and 1 x -80ºC/+25ºC 24 hours freeze-thaw cycle and autoclave 20min @120°C

Empicol® is a registered trademark of Hutsman

This formulation was developed in France. Contact your local sales representative with enquiries as ingredient availability can vary by region.

Non-warranty
The information in this publication is believed to be accurate and is given in good faith, but no representation or warranty as to its completeness or accuracy is made.
Suggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose. No
representation or warranty, expressed or implied, is made with respect to information or products including, without limitation, warranties of merchantability, fitness for a
particular purpose, non-infringement of any third party patent or other intellectual property rights including, without limit, copyright, trademark and designs. Any trademarks
identified herein, unless otherwise noted, are trademarks of the Croda group of companies.
©2018 Croda International Plc
www.sederma.com sederma@sederma.fr
www.crodarom.com marketing@crodarom.fr
www.crodapersonalcare.com
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Development Formulation

www.sederma.com sederma@sederma.fr
www.crodarom.com marketing@crodarom.fr
www.crodapersonalcare.com
Asia Pacific pc-asia@croda.com Latin America marketinglatam@croda.com 03/18PCSDF0065V2EN
Europe, Middle East & Africa pc-europe@croda.com North America marketing-usa@croda.com Page 2 of 2