DRUG NAME MODE OF INDICATION CONTRAINDICATIO SIDE/ADVERSE NURSING

ACTION N EFFECTS CONSIDDERATION

S
GENERIC NAME: Tranexamic Anti- Hypersensitivity > Side effects: 1.Unusual change in
Tranexamic acid acid (TXA) is a Fibrinolytic Active Intravascular CNS: Dizziness bleeding pattern should
BRAND NAME: medication that Action: TXA is Clotting EENT: Visual Abnormalities be immediately
Cyklokapron works by an Acquired defective color CV: Hypotension, reported to the
THERAPEUTIC inhibiting the antifibrinolytic vision thromboembolism, physician.
CLASS: breakdown of agent, which Subarachnoid thrombosis
Antifibrinolytic blood clots. It means it Hemorrhage Precautions: GI: Diarrhea, nausea, 2. For women who are
PHARMACOLOGI is not typically interferes with Use cautiously with renal vomiting taking Tranexamic acid
C CLASS: used to treat the body's impairment, hematuria to control heavy
Hemostatic agent myomas natural originating in the upper bleeding, the
ACTUAL DOSE, (uterine processes of urinary tract; and medication should only
TIMING, AND fibroids) breaking down conditions associated be taken during the
ROUTE: 500mg IV directly but blood clots. with increased thrombus menstrual period.
now then Q8H may be Reducing formation Interactions: >
prescribed in Blood Loss: In drug-drug: concurrent 3. Tranexamic Acid
specific the context of use of clotting factor should be used with
situations to myomas, which complexes may the risk extreme caution in
manage heavy can cause of thrombotic CHILDREN younger
menstrual heavy complications (give than 18 years old;
bleeding caused menstrual tranexamic acid 8 hr safety and effectiveness
by myomas. bleeding following clotting factor in these children have
(menorrhagia), replacement therapy) not been confirmed.
TXA can be
prescribed to 4. Unusual change in
reduce the bleeding pattern should
excessive blood be immediately
loss. By reported to the
preventing the physician.
premature
breakdown of 5. For women who are
blood clots in taking Tranexamic acid
the uterine to control heavy
lining, TXA bleeding, the
helps minimize medication should only
bleeding during be taken during the
menstruation. menstrual period.
Menstrual
Bleeding 6. The medication can
Control: TXA be taken with or
is particularly without meals.
effective in
controlling 7. If you miss a dose of
heavy Tranexamic Acid, take
menstrual it when you remember,
bleeding. It can then take your next
reduce the dose at least 6 hours
duration and later. Do not take 2
severity of doses at once.
menstrual
periods. 8. Inform the client that
Non-Hormonal he/she should inform
Option: TXA is the physician
a non-hormonal immediately if the
treatment, following severe side
making it a effects occur: Severe
suitable choice allergic reactions such
 for women who as rash, hives, itching,
cannot or do dyspnea. tightness in
not wish to use the chest, swelling of
hormonal the mouth, face, lips or
medications to tongue, Calf pain,
manage swelling or tenderness,
myoma-related Chest pain.
bleeding.
9. Swallow Tranexamic
Acid whole with plenty
of liquids. Do not
break, crush, or chew
before swallowing.
10. Store this
medication at room
temperature away from
moisture and heat.
1.Monitor BP carefully
when discontinuing
clonidine; hypertension
usually returns
within48 hr
2.Dosage Calculation:
Ensure the correct
dosage is prescribed
Blood Pressure and administered.
Regulation: Clonidine is 3. Advise patient to
Clonidine's contraindicated in take drug exactly as
primary patients with a history of prescribed and not to
Clonidine is a therapeutic sensitization or allergic stop abruptly because
GENERIC NAME: medication effect is the reactions to clonidine. CNS: drowsiness, dizziness, withdrawal symptoms
Clonidine primarily used lowering of Epidural administration sedation, weakness, fatigue, and severe
BRAND NAME: to treat high blood pressure. is contraindicated in the malaise, agitation, depression hypertension may
“Catapres”, Catapres- blood pressure It acts in the presence of an injection CV: bradycardia, severe occur.
TTS, Duraclon, (hypertension) brain to reduce site infection, in patients rebound HNT, orthostatic 4.Instruct patient to
Jenloga, and Kapvay and certain sympathetic on anticoagulant therapy hypotension consult prescriber if
THERAPEUTIC other nervous system and in those with a GI: constipation, dry mouth, dry mouth or
CLASS: conditions, but activity, bleeding diathesis. nausea, vomiting, anorexia, drowsiness becomes a
Antihypertensive it does not have leading to GU: urine retention, erectile problem.
PHARMACOLOGI a direct mode decreased heart dysfunction 5. During oral
C CLASS: centrally of action on rate and blood Metabolic: weight gain clonidine therapy.
acting alpha-agonist myomas vessel Skin: pruritus, dermatitis Tominimize these
hypotensive agents (uterine constriction. with transdermal patch, rash effects, prescriber may
ACTUAL DOSE, fibroids). This results in suggest taking most of
TIMING, AND Clonidine reduced blood dosage at bedtime.
ROUTE: works by acting pressure, 6. Instruct patient to
75mcg tab, 1 tab SL on specific making it an report chest
now rep BP after receptors in the effective pain,dizziness with
30mins central nervous antihypertensiv position
system. e medication. changes,excessive
Pain drowsiness, rash, urine
Management: retention, and vision
Clonidine is changes. As needed,
also used in tell patient to rise
some cases for slowly to avoid
pain hypotensive effects.
management, 7. Assess blood
particularly for pressure and apical
neuropathic pulse before initial
pain, as it can dose. Ifsystolic blood
modulate the pressure is <90
transmission of mmhgor pulse is <60
pain signals in bpm,with hold drug
the central and notify physician.
nervous 8.Check for edema
system. infeet, legs daily,
9. Monitor input-
output ratio: check for
decreasing output.
10. Note allergic
reactions: fever, rash,
pruritus, urticaria,
andioedema.
 1.Assess for allergy to
any ingredient, sulfite;
hemochromatosis,
hemosiderosis,
haemolytic anemias
2. Assess for skin
lesions, color; gums,
teeth (color); bowel
sounds
3. Confirm that client
Myomas, does have iron
especially when deficiency anemia.
they cause Contraindicated with 4. administer the right
heavy allergy to any ingredient; drug in the right dose
menstrual sulphite allergy; and route at the right
bleeding hemochromatosis, time > do not crush,
(menorrhagia), hemosiderosis, chew or cut tablets and
can lead to iron haemolytic anemias capsules
GENERIC NAME: deficiency Precaution: Use 5. Give drug with
Ferrous Sulfate Its mode of anemia in some cautiously with normal CNS: CNS toxicity, acidosis, meals (avoiding milk,
BRAND NAME: action is related women. iron balance; peptic coma, and death with eggs, coffee, and tea)
Slow FE, Fer-In-Sol, to correcting Ferrous sulfate ulcer, regional enteritis, overdose 6. Administer liquid
Feratab, “Iron”, Mol- iron deficiency is often ulcerative colitis GI: GI upset, anorexia, preparations in water or
Iron, Feosol, and and anemia, prescribed to Interactions: nausea, vomiting, juice to mask the taste
MyKidz Iron 10 which can be address the drug-drug: decreased nti- constipation, diarrhea, dark and prevent staining of
THERAPEUTIC caused by anemia infective response to stools, temporary staining of teeth; have patient
CLASS: Iron various factors, associated with ciprofloxacin, teeth drink solution with a
Preparation including heavy myomas by norfloxacin, ofloxacin; straw
PHARMACOLOGI menstrual replenishing decreased effects of 7. Do not take this
C CLASS: Iron bleeding iron stores and levodopa if taken with drug with antacids nor
Preparation associated with supporting red iron; tetracyclines unless
ACTUAL DOSE, myomas. blood cell absorption with antacids, prescribed.
TIMING, AND production. cimetidine; decreased 8. Warn patient that
ROUTE: 1 tab OD increased serum iron stool may be dark or
PO levels with green
chloramphenicol 9. Arrange for periodic
drug-food: decreased monitoring of Hct and
absorption with antacids, Hgb levels
eggs or milk, coffee and 10. keep this drug out
tea; avoid concurrent of reach of children
administration of any of (may cause fetal
those poisoning)
 1.Caution patient to
avoid salt substitutes
containing potassium
or foods containing
high levels of
potassium or sodium
unless directed by
health care
professional.
2.Caution patient to
avoid sudden changes
in position to decrease
Blood Pressure orthostatic
Regulation: Hypersensitivity to drug hypotension. Use of
The primary or its components alcohol, standing for
therapeutic Pregnancy (second and) long periods,
effect of trimesters) Precautions exercising, and hot
losartan is the Use cautiously in: weather may increase
reduction of heart failure, renal or orthostatic
blood pressure. hepatic impairment, hypotension.May cause
It can help obstructive biliary dizziness.
manage disorders high-dose 3. Caution patient to
hypertension diuretic therapy black avoid driving or other
GENERIC NAME: and reduce the patients pregnant patients activities requiring
Losartan Losartan is risk of (first trimester) or alertness until response
BRAND NAME: used primarily cardiovascular breastfeeding patients, CNS: dizziness, insomnia, to medication is
Cozaar to treat high events children younger than headache,asthenia, known.
THERAPEUTIC blood pressure associated with age 6 (safety not fatigueCV: hypotension 4.Advise patient to
CLASS: Angiotensin (hypertension). high blood established). EENT: sinus disordersGI: notify health care
receptor blockers Its mode of pressure. nausea, vomiting, diarrhea, professional of all Rx
(ARBs) action is Cardiovascular dyspepsia, abdominal or OTC medications,
PHARMACOLOGI focused on its Protection: painMetabolic: vitamins, or herbal
C CLASS: antihypertensiv Losartan may hyperkalemiaMusculoskeleta products being taken
Angiotensin II e properties and provide l: joint pain, back and to consult with
ACTUAL DOSE, the renin- additional pain,muscle cramps health care professional
TIMING, AND angiotensin- cardiovascular Respiratory: symptoms of before taking other
ROUTE: 100mg, 1 aldosterone protection by upper respiratory infection, medications.
tab OD AM PO system. reducing the dry cough 5. Instruct patient to
strain on the Other: hypersensitivity notify health care
heart and blood reactionsincluding professional if swelling
vessels. It is angioedema of face, eyes, lips, or
sometimes used tongue or if difficulty
in patients with swallowing or
heart failure or breathing occur.
a history of 6. Emphasize the
stroke to importance of follow-
manage blood up exams to evaluate
pressure and effectiveness of
improve overall medication.
heart health. 7. Hypertension:
Encourage patient to
comply with additional
interventions for
hypertension (weight
reduction, low-sodium
diet, discontinuation of
smoking, moderation
of alcohol
consumption, regular
exercise, stress
management).
Medication controls but
does not cure
hypertension.
8. Instruct patient and
family on proper
technique for
monitoring BP. Advise
them to check BP at
least weekly and to
report significant
changes.
9. Instruct patient to
notify health care
professional of
medication regimen
before treatment.
10. Emphasize the
importance of
continuing to take as
directed, even if
feeling well. Take
missed doses as soon as
remembered if not
almost time
for next dose; do not
double doses.
Medication controls but
does not cure
hypertension.

1. Provide information
to the patient about the
medication, its purpose,
potential side effects,
 and the importance of
compliance.
2. Use cautiously in
patients with heart
block, heart failure or
severe aortic stenosis.
3. Instruct patient to
Blood Pressure immediately notify
Reduction: By prescriber of dizziness,
inhibiting arm or leg swelling,
calcium difficulty breathing,
channels, hives or rash.
amlodipine 4. Advise patient to
reduces the Hypersensitivity to have his blood pressure
contraction of amlodipine checked to monitor for
blood vessels, hypotension.
leading to 5. Patients with liver
vasodilation. disease remove this
This dilation of drug from their systems
blood vessels very slowly thus
lowers systemic necessitating
vascular modification of the
resistance, dosing regimen -Check
which blood pressure an hour
decreases blood or two after
pressure. administering the drug.
GENERIC NAME: Reduced 6. Monitor patient
Amlodipine Cardiac carefully (BP, cardiac
BRAND NAME: Amlodipine is a Workload: rhythm, and output)
“Norvasc” and medication Amlodipine's Frequent: Peripheral edema, while adjusting drug to
Katerzia primarily used vasodilatory Headache, Flushing therapeutic dose; use
THERAPEUTIC to treat high effect reduces Occasional: Dizziness, special caution if
CLASS: blood pressure the heart's palpitation, nausea, unusual patient has CHF.
calcium channel (hypertension) workload by fatigue or weakness 7. Monitor BP very
blockers and certain making it easier Rare: Chest pain, carefully if patient is
PHARMACOLOGI heart for the heart to Bradycardia, Orthosatic also on nitrates.
C CLASS: conditions. pump blood hypotension 8. Monitor cardiac
calcium channel Amlodipine's through relaxed rhythm regularly
blockers primary blood vessels. during stabilization of
ACTUAL DOSE, mechanism of This can be dosage and periodically
TIMING, AND action is related beneficial for during long-term
ROUTE: to its effects on individuals therapy.
10mg tab, 1 tab OD the with 9. Administer drug
PM PO cardiovascular hypertension or without regard to
system such as certain heart meals.
calcium conditions, as it 10. Report irregular
channel can help lower heartbeat, shortness of
blockade and blood pressure breath, swelling of the
blood pressure and improve hands or feet,
reduction overall cardiac pronounced dizziness,
function. constipation.
Management of
Hypertension:
Amlodipine is
primarily used
to treat high
blood pressure
and help
maintain blood
pressure within
 a normal range.
This can reduce
the risk of
heart-related
complications
associated with
hypertension.

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