ZOOLOGY

18 Biotechnology And Its Application

C) increasing the use of agrochemicals

BASIS OF CLASSIFICATION
D) Both A & C
1. Biotechnology mainly deals with 7. Use of genetically modified crops in crop
[pg-207,E] field may [pg-208,M]
A) Industrial scale production of A) reduce the harmful effects of
biopharmaceutical fertilizers
B) Biological use of genetically modified B) maximize yield
microbes, fungi, plants and animals C) be environment friendly
C) Both A and B D) All of the above
D) None of these 8. Plants bacteria, fungi and animals whose
2. Which of the following is not included in genes have been altered by manipulation
the application of biotechnology- are called [pg-208,M]
[pg-207,E] A) Pest resistant organism
A) Waste treatment B) Hybrid organisms
B) Conventional hybridisation C) Genetically modified organism
C) Energy production D) Insect resistant organism
D) Genetically modified crops 9. Golden rice is genetically modified crop
3. Application like bioremediation, plant with incorporate gene meant for
processed food, therapeutics and biosynthesis of [pg-208,M]
diagnostics are related to [pg-207,E] A) Vitamin E B) Vitamin K
A) Biochemistry C) Omega-3 D) Vitamin A
B) Microbiology 10. ____ produced by Bacillus thuringiensis
C) Biotechnology [pg-208,E]
D) Medical Science A) t- toxin B) Bt toxin
4. ____ is/are the critical research area(s) of C) An acid D) All of these
biotechnology. [pg-207,E] 11. The bacterium Bacillus thuringiensis
A) Creating optimals conditions for produce ____ plants which reduces the
catalyst function amount of ____ used. [pg-208,M]
B) Providing best catalyst A) disease resistant, insecticide
C) Developing down streaming B) insect resistant, fertilizers
processing technique C) disease resistant, industrial enzyme
D) All of the above D) insect resistant, insecticide
PARAGRAPH- 12.1 BIOTECHNOLOGY 12. Which of the following crops are modified
APPLICATIONS IN AGRICULTURE using Bacillus thuringiensis? [pg-208,E]
A) Corn and cotton
5. Which of the following is not for B) Tomato and rice
increasing food production? [pg-208,E] C) Potato and soyabean
A) Agrochemical based agriculture D) All of the above
B) Organic agriculture 13. Which of the following is being grown in
C) Genetic engineered crop-based India by farmers as Bt crop? [pg-208,E]
agriculture A) Maize B) Brinzal
D) None of these C) Cotton D) Soyabean
6. Organic agriculture is a technique of 14. By inserting a piece of DNA from ____
raising crops for [pg-208,M] insect resistant transgenic cotton has
A) increased food production been produced. [pg-208,H]
B) reduction in required labour A) a wild relative of cotton
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B) bacterium A) Cry I Ac, Cry II Ab

C) an insect B) Cry I Ac, Cry II Ac, Cry I Ab
D) virus C) Cry II Ac, Cry I Ab
15. Some strains of Bacillus thuringiensis D) Cry I Ab
produce proteins that will insect like 24. Bt corn has been made resistant to corn
[pg-208,H] borer by the introduction of gene
A) Lepidopterans B) Coleopterans [pg-209,H]
C) Dipterans D) All of these A) Cry I Ac B) Cry II Ab
16. Coleopterans examples are/is- C) Cry I Ab D) Cry II Ac
[pg-208,E] 25. Cry II Ab and Cry I Ab produces toxins
A) Flies B) Mosquitoes that control [pg-209,M]
C) Beetles D) All of the above A) Cotton bollworms and corn borer
17. Bacillus thuringiensis forms protein resp.
crystals which contain a- [pg-208,H] B) Cotton bollworm and budworms of
A) Simple protein tobacco resp.
B) Non-toxic insecticidal protein C) Corn borer and cotton bollworms
C) Toxic insecticidal protein resp.
D) Simple lipids D) Nematodes and tobacco budworms
18. Why does Bt toxin protein crystal not kill resp.
the Bacillus? Because- [pg-208,M] 26. Which of the following nematodes infects
A) Bacteria encloses toxins in special the root of the tobacco plants which
sac reduces the production of tobacco?
B) Bacteria are resistant to toxin [Pg-209,H]
C) Toxin occurs as inactive protoxins in A) Melodiogyne incognitia
bacteria B) Ascaris
D) All of the above C) Wuckereria
19. Bt toxin kills insect by- [pg-209,M] D) Interobious
A) Inhibiting protein synthesis 27. A Novel strategy was adopted to present
B) Generating excessive heat Meloidiogyne incognita infection in
C) Creating pores leading to cell tobacco plants that was based on the
swelling and lysis in the mid gut process of [Pg-209,M]
epithelial cells A) DNA interference
D) None of these B) RNA interference
20. The choices of genes of Bacillus C) RNA initiation
thuringiensis, incorporated in to crop D) DNA initiation
depends upon [pg-209,M] 28. Resistance against a Nematode was
A) Crop B) Targeted pest introduce by implying RNA in ____
C) Both A and B D) Toxin plants. [pg-209,E]
21. The crops having cry genes need A) Tomato B) Bt corn
[pg-209,M] C) Bt cotton D) Tobacco
A) Small amount of fungicide 29. RNAi stand for [pg-209,E]
B) Large amount of pesticide A) RNA inteteron
C) Small amount of insecticide B) RNA interference
D) None of the above C) RNA inactivation
22. The Bt toxin protein [pg-209,E] D) RNA initiation
A) Obstruct a biosynthetic pathway 30. RNAi take place in all ____ organisms as
B) Causes death of the insect method of ____. [pg-209,M]
C) Stops egg laying of adult A) prokaryotes, insect resistant
D) Generating excessive heat B) eukaryotes, insect resistant
23. Cotton bollworm controlled by- C) eukaryotes, cellular defence
[pg-209,M]
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D) prokaryotes, cellular defence C) C-chain D) Both A and B

31. ____ is used for silencing of an unwanted 39. The main challenge for production of
gene [Pg-209,M] insulin using rDNA techniques was
A) RNA [Pg-211,M]
B) DNA polymerase A) Splitting A and B- peptide chains
C) Restriction enzyme B) Addition of C- peptide to proinsulin
D) All of these C) Getting insulin assembled to mature
32. Silencing of mRNA molecule in order to form
control the production of a harmful D) Removal of C- peptide from active
protein has been used in the protection insulin
of plants from [Pg-209,H] 40. Which of the following companies
A) Beetles B) Armyworm prepared human insulin in 1983?
C) Budworm D) Nematodes [Pg-211,E]
33. Transposons are also known as A) Monsanto B) Eli Lily
[Pg-209,E] C) Genetech D) GEAC
A) Silenced gene PARAGRAPH-12.2.2 GENE THERAPY
B) Plesotropic genes
C) Mobile genetic elements 41. Treatment of genetic disorder by
D) Both A and C
manipulating gene is called- [Pg-211,M]
34. Tobacco plant resistant to a nemotode
A) Gene therapy
have been developed by the introduction B) rDNA technology
of DNA and it is produced in the lost cells C) Bone marrow transplantation
as [Pg-209,M] D) Enzyme replacement therapy
A) A particular hormone 42. For the first time, therapy was tried on a
B) Toxic protein 4 year old girl in 1990 to treat ____.
C) Both sense and antisense RNA [Pg-211,E]
D) An antifeedant A) Cytosine Deaminase (CDA)
PARAGRAPH-12.2 BIOTECHNOLOGY B) Adenosine Deaminase (ADA)
APPLICATIONS IN MEDICINE C) Tyrosine oxidase
D) Glutamate tryhydrogenase
35. The first human hormone produced by 43. Which kind of therapy was given in 1990
recombinant technology is [Pg-210,E] to 4 year old girl with enzyme deficiency?
A) Oestrogen B) Progesterone [Pg-211,E]
C) Thyroxine D) Insulin A) Gene therapy
36. The demerits of using bovine insulin B) Chemotherapy
(from cow) and porcine insulin (from pig) C) Immunotherapy
in diabetic patients is- [Pg-211,M] D) Radiation therapy
A) It leads to hypercalcemic 44. Adenosine deaminase (ADA) deficiency
B) It may cause allergic reaction can be treated by ____ and ____ but it is
C) It is expensive not fully curative. Here A and B can be
D) All of the above [Pg-211,M]
37. The two polypeptides of human insulin A) A- gene therapy, B- radiation
are linked together by [Pg-211,M] therapy
A) Phosphodiester bonds B) A- bone marrow transplantation, B-
B) Disulphide bridge enzyme replacement therapy
C) Hydrogen bonds C) A- organ transplantation, B-
D) None of the above hormone replacement
38. ____ is removed during the maturation of D) A- radiation therapy, B- enzyme
proinsulin to insulin. [Pg-211,H] replacement therapy
A) A-chain B) B-chain
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45. The advantage of beginning gene therapy 51. Technique used to detect mutation in
prior to birth is- [Pg-211,H] genes is known as- [Pg-212,E]
A) The body would not reject it as it A) Gel electrophoresis
has not yet recognised 'self'. B) PCR
B) This would give the body plenty of C) Gene therapy
time. D) Autoradiography
C) The cell being extremely young are 52. Which of the following technique is based
more receptive to gene therapy. on the principle of antigen – antibody
D) None of these interaction? [Pg-212,H]
PARAGRAPH-12.2.3 MOLECULAR A) PCR
DIAGNOSIS B) ELISA
C) Recombinant DNA technology
46. Why using conventional method for D) Gene therapy
diagnosis is not very relevant? PARAGRAPH-12.3 TRANSGENIC
[Pg-212,M] ANIMALS
A) Early detection is not possible
B) Not reliable 53. Animals whose DNA is manipulated to
C) Results are incorrect possess and express an extra (foreign)
D) All of these gene are known as [Pg-212,E]
47. Which of the following molecular A) Transgenic animals
diagnostic technique is used to detect the B) Hybrid animals
presence of a pathogen in its early stage C) Transferrin animals
of infection- [Pg-212,E] D) All of the above
A) Angiography 54. Transgenic animals are those which have
B) Radiography foreign? [Pg-212,M]
C) Enzyme replacement technique A) DNA in all of their cells
D) Polymerase chain reaction B) Proteins in all of their cells
48. Why PCR is used? [Pg-212,E] C) RNA in all their cells
A) to detect HIV in suspected AIDS D) RNA in some of their cells
patients 55. 95% of all the existing transgenic
B) to detect Mutation in the genes of animals are [Pg-212,E]
suspected cancer patients A) Pigs B) Cows
C) Diagnose many genetic disorders C) Mice D) All of these
D) All of the above 56. Transgenic animals can be used to
49. A single stranded Nucleic acid tagged [Pg-212,213,E]
with a radioactive molecule is called A) Study normal physiology
[Pg-212,E] B) Study the biological effects
A) Plasmid C) Study the vaccine safety
B) Probe D) All of the above
C) Vector 57. Transgenic animals made to serve as
D) Selectable market models for human diseases. The disease
50. In which of the following method, a probe are- [Pg-213,M]
is allowed hybridise to its complementary A) Alzheimer's disease
DNA in the clone of cells? [Pg-212,M] B) Cancer
A) Enzyme linked Immono sorbent C) Cystic fibrosis
Assay (ELISA) D) All of these
B) PCR 58. Which of the following transgenic human
C) Autoradiography protein products development are used
D) Gene therapy to treat emphysema? [Pg-213,H]
A) 𝛼-1 antitrypsin B) 𝛼-1 trypsin
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C) 𝛼-1 albumin D) 𝛼-1 globulin invented a new process of making a

59. When was the first transgenic cow, Rosie product is called- [Pg-214,M]
produced? [Pg-213,E] A) bioethics
A) 1979 B) 1997 B) patent
C) 1996 D) 1999 C) bio piracy
60. ____ was introduced in the first trans D) genetic recombination
genetic cow- [Pg-213,M] 66. Bio patent means [Pg-214,E]
A) 𝛼-1 antirypsin A) Right to use an invention
B) Human 𝛽-Lactalbumin B) Right to use application are
C) 𝛽-1 antitrypsin processes
D) None of these C) Both A and B
61. The first transgenic cow, Rosie produced D) None of these
[Pg-213,H] 67. ____ have been present in India from long
A) Human calcium enriched milk (2.4 time yet foreign country got patent
g/l) through the US patent and Trademark
B) Human protein enriched milk (2.4 office. [Pg-214,M]
g/l) A) Brown rice B) Basmati rice
C) Human calcium enriched milk (2.6 C) Co-667 D) All of these
g/l) 68. Bioethics is- [Pg-214,E]
D) Human protein enriched milk (2.8 A) Process of discovery and
g/l) commercialisation of new products.
62. ____ are used in testing safety of polio B) Use of bio resources with proper
vaccine before they are used on human. authorisation.
[Pg-213,E] C) Standards used to regulate human
A) Transgenic pig activities in relation to the biological
B) Transgenic monkey world.
C) Transgenic rabbits D) All of these
D) Transgenic mice 69. Exploitation of bio resources of a nation
63. ____ animals are made that carry genes by multinational companies without
which makes them more sensitive to authorisation from the concerned
toxic substances than non-transgenic country is referred to- [Pg-214,E]
animals. [Pg-213,M] A) Bioethics
A) Transgenic B) Mutaled B) Bioweapon
C) Transverred D) Transformed C) Bio piracy
D) Bio-exploitation
PARAGRAPH-12.4 ETHICAL ISSUE
70. Bio piracy is related with the- [Pg-214,E]
64. Which committee takes decision A) Stealing of bio resources
regarding the validity of GM research and B) Traditional knowledge and
the safety of introducing GM-organisms utilization
for public services? [Pg-213,E] C) Biomolecules and regarding bio
A) Indian Council of Medical Research resources exploitation
(ICMR) D) Both A and C
B) Genetic Engineering Approval 71. ____ was taken by Indian parliament to
committee (GEAC) meet and fulfill the requirements of
C) Indian Institute of Science patent terms and other emergency
Education and Research (IISER) provisions in this regard? [pg-214,E]
D) Genetic Engineering Appraisal A) Indian patents bill
Committee (GEAC) B) Bioethics act
65. A ____ granted to a person who has either C) Bio piracy act
invented a new and useful product, made D) All of these
improvement existing product or
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