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THE BRAIN FROM TOP TO BOTTOM http://thebrain.mcgill.ca/flash/a/a_03/a_03_p/a_03_...

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SEEKING PLEASURE AND AVOIDING PAIN

Pleasure-Seeking Our most powerful motivations come from behaviours that have proven beneficial to our species from an
Behaviour evolutionary standpoint. Specialized systems in the brain have thus evolved to give us pleasure when we
engage in these behaviours.
Pleasure and Drugs
Avoiding Pain The brain has two major pathways that help to activate behaviours: the reward circuit, which is part of the
medial forebrain bundle (MFB); and the punishment circuit, or periventricular system (PVS).

Both the MFB, through the desire/action/satisfaction cycle, and the PVS, through the successful fight or
flight response, lead the organism to behave in a way that preserves its homeostasis. Together, they form
the behavioural approach system (BAS).

Opposing the BAS is the behavioural inhibition system (BIS), characterized by Henri Laborit in the early
1970s. Stimulation of the BIS causes an overall inhibition of behaviour, thus working against the BAS.

Neural Darwinism

Protect Your Immune System


by Refusing To Be Dominated!

The motivating effect that


rewards have on
behaviour is universally
recognized, though the
exact role of pleasure is
still debated. Is pleasure
a determining factor in
whether an individual
evinces a particular
behaviour, or simply a Under natural conditions, the BIS is activated when we observe that our actions will be ineffective. When
concomitant of the fight or flight appears impossible, very often the only choice left to ensure survival is to submit and accept
behavioural response? things as they are. The BIS is the result of an evolutionary history in which this system made itself useful by
Either way, the operating intermittently, temporarily preventing any useless actions that could only have made matters
motivations that drive our worse.
behaviour appear to be
intimately linked to For example, consider a small mammal in the middle of a field who suddenly sees a bird of prey flying
pleasure. overhead. The best thing to do is not to move, in the hope of not being seen. In human societies based on
competition, many people activate their behavioural inhibition system continually, to avoid reprisals.

In such cases, the inhibition of behaviour is no longer merely an adaptive interval between approach and
avoidance behaviours, but instead becomes a chronic source of anxiety. This sense of uneasiness
gradually undermines the individual’s health. Indeed, the inhibition of behaviour has many negative
consequences, and they have been abundantly documented. The most obvious ones are psychosomatic
illnesses, stomach ulcers, and arterial hypertension. But prolonged activation of the BIS can also lead to
more serious genetic disorders such as cancers and all of the pathologies associated with impaired
immune function.

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THE BRAIN FROM TOP TO BOTTOM http://thebrain.mcgill.ca/flash/a/a_03/a_03_p/a_03_...

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