INTRODUCTION than 4 times a year, with total resolution

between attack intervals. Meanwhile, acute

Rhinosinusitis is a disease that is
exacerbation of chronic rhinosinusitis is a
often found and affects the quality of life
sudden worsening of the symptoms of
and health of individuals which in turn will
patients, who have been diagnosed with
have an impact on economic and
chronic rhinosinusitis, such as early
employment problems (Rosenfeld et al.
symptoms before being given treatment
2015).
(Bailey et al. 2014).
Rhinosinusitis is inflammation of
Prevalence for CRS varies
the paranasal sinuses and nasal mucosa,
substantially with rates ranging from 1.0%
which is characterized by symptoms
to 12.1% across the world (Xu et al. 2016).
of nasal congestion, the presence of
Chronic rhinosinusitis affects 5-15% of
nasal secretions from both anterior and
the population in Europe and the United
posterior nasal drips, accompanied by
States with an increasing prevalence with
symptoms of spontaneous facial pain or
increasing age, with a mean of 2.7% in the
compression in the sinus area and
20- 29 age group and 6.6% 50-59 years.
decreased or lost smell (Rosenfeld et al.
After 60 years of age, the prevalence rate
2015).
of CRS decreases to 4.7% (Fokkens et al.
Rhinosinusitis is divided into
2020). The prevalence of CRS varies in
several types according to the duration of
Asian countries. A review revealed that
symptoms felt by the patient based on the
the prevalence of CRS in Asia ranged
classification made by the Task Force of
widely from 2.1 to 28.4%. South Korea
The American Academy of
established the Korea National Health and
Otolaryngology-Head and Neck Surgery
Nutrition Survey (KNHNS) and published
(AAO-HNS), namely: acute rhinosinusitis,
a series of studies about the prevalence and
subacute rhinosinusitis, chronic
risk factors of CRS in recent years. The
rhinosinusitis, chronic rhinosinusitis acute
prevalence of CRS was 6.95% among
exacerbation, and recurrent acute
4,098 subjects, and the risk factors for
rhinosinusitis. Acute rhinosinusitis lasts no
CRS included heavy stress, influenza
more than 4 weeks. Sub-acute
vaccination, septal deviation, and
rhinosinusitis, lasting between 4-12 weeks.
persistent allergic rhinitis (AR). While in
Chronic rhinosinusitis can last more than 12
2008–2012, the prevalence of CRSwNP
weeks. Recurrent acute rhinosinusitis, is a
and CRSsNP in 28,912 adults was 2.6 and
symptom experienced by the patient more
5.8%, respectively, in 2010–2012, the