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  • ELL890-fMRI-lecture 1-Slides

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    This document discusses fMRI processing and analysis. It explains that fMRI measures the blood oxygen level dependent (BOLD) signal, which is related to neural activity levels. When neurons are active, they consume oxygen from blood flow, and the ratio of oxygenated to deoxygenated hemoglobin provides information about brain activation over time. The document also covers topics like the hemodynamic response function, 4D fMRI data, structural vs functional MRI, spatial normalization to a standard brain template, experiment design, and using the generalized linear model to analyze fMRI data statistically.

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    ELL890-fMRI-lecture 1-slides

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    This document discusses fMRI processing and analysis. It explains that fMRI measures the blood oxygen level dependent (BOLD) signal, which is related to neural activity levels. When neurons are active, they consume oxygen from blood flow, and the ratio of oxygenated to deoxygenated hemoglobin provides information about brain activation over time. The document also covers topics like the hemodynamic response function, 4D fMRI data, structural vs functional MRI, spatial normalization to a standard brain template, experiment design, and using the generalized linear model to analyze fMRI data statistically.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    25 views9 pages

    ELL890-fMRI-lecture 1-Slides

    Uploaded by

    runit
    This document discusses fMRI processing and analysis. It explains that fMRI measures the blood oxygen level dependent (BOLD) signal, which is related to neural activity levels. When neurons are active, they consume oxygen from blood flow, and the ratio of oxygenated to deoxygenated hemoglobin provides information about brain activation over time. The document also covers topics like the hemodynamic response function, 4D fMRI data, structural vs functional MRI, spatial normalization to a standard brain template, experiment design, and using the generalized linear model to analyze fMRI data statistically.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    of 9

    fMRI Processing

    and Analysis

    Rohit Misra
    MS(R) Student
    Neurocomputing Lab
    Dept. of Electrical Engineering
    IIT Delhi
    Blood Oxygen Level Dependent
    Signal

    • Neural activity
    requires energy
    • Energy is supplied via
    oxygenated blood
    • Oxyhemoglobin is
    diamagnetic, and
    deoxyhemoglobin is
    paramagnetic
    Presentation title
    Blood Oxygen Level Dependent
    Signal
    Hemodynamic Response Function (HRF) Repeated stimulation

    3
    Functional MRI
    BOLD for repeated stimuli

    4 Dimensional Data

    BOLD(x, y, z, t)

    Presentation title
    Structural vs Functional MRI

    Presentation title 20XX 5


    MNI Standard Template

    Presentation title 20XX 6


    fMRI Pre-Processing

    7
    Experiment Design

    Presentation title 20XX 8


    Generalized Linear Model

    Presentation title 20XX 9

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