CPC Aseptic Connections

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Distributed By:

01235 750 690


info@biopharmadynamics.com
www.biopharmadynamics.co.uk

ASEPTIC CONNECTION
TECHNOLOGY
INTRODUCING

MicroCNX

SERIES CONNECTORS

TUBE WELDING IS NO MATCH FOR THE NEW SMALL-FORMAT,


SINGLE-USE MICROCNX ™ SERIES CONNECTORS.
Experience a smaller, smarter, faster, and easier way to make sterile connections.

VISIT ENDOFTHEWELD.COM.

NOMINAL FLOW PATH (NFP) SIZE

NFP Cv VALUE NFP Cv VALUE NFP Cv VALUE

1/8” 0.27 3/32” 0.14 1/16” 0.04

cpcworldwide.com · 1-800-444-2474 13 cpcworldwide.com/bio · 1-800-519-7633


ASEPTIC STERILE CONNECTION
MICROCNX™ SERIES DIMENSIONS AND WEIGHTS

MICROCNX ™ POLYCARBONATE with teal cover For autoclave or gamma irradiation applications.
TERMINATION METRIC EQ. PART NO. PART WEIGHT

SERIES CONNECTORS
1/8” HOSE BARB 3.2 mm CNX17002HT 0.93" (23.6 mm) 2.25" (57.2 mm) 1.49" (37.8 mm) 0.27 oz (7.64 g)

3/32” HOSE BARB 2.4 mm CNX17003HT 0.93" (23.6 mm) 2.16" (54.9 mm) 1.49" (37.8 mm) 0.27 oz (7.62 g)

MicroCNX™ Connectors introduce a new category


1/16” HOSE BARB 1.6 mm CNX17001HT 0.93" (23.6 mm) 2.05" (52.1 mm) 1.49" (37.8 mm) 0.27 oz (7.60 g)
of aseptic micro-connectors that provide a simple, efficient
method of connecting tubing for small-format biomanufacturing
assemblies. MicroCNX connectors are the modern alternative
to the cumbersome, industrial process of tube welding.
Building on the inventiveness of CPC, the leader in single-use
PRODUCT DIMENSIONS
connection technology, the MicroCNX line of connectors is
engineered specifically for the challenging conditions of biologic
media transfer in bioprocessing, cell therapy and gene therapy
= Height
applications.
= Total Length
= Total Width

SPECIFICATIONS FEATURES BENEFITS


Intuitive three-step connection process reduces risk
OPERATING PRESSURE PINCH-CLICK-PULL
of operator error
Up to 60 psi, 4.1 bar
Lowers risk of operator error and related
Up to 75 psi, 5.1 bar for 48 hours Easy to use
performance, reliability and safety concerns

OPERATING TEMPERATURE Genderless


Eases single-use systems specifications with one
34°F to 104°F (1°C to 40°C) part number for both halves

TERMINATIONS CPC Click


Audible confirmation of assembly with no additional
hardware required
1/16”, 3/32” 1/8” ID hose barb (1.6mm,
2.4mm, 3.2mm)

MATERIALS TYPICAL FLOW RATE NOTE


Cv Value Range: 0.04-0.27
Main Components: Polycarbonate (white),
USP Class VI, ADCF
for MicroCNX hose barb terminations
Validation and Extractables data can be MICROCNX™ CONNECTORS ASSEMBLY PROCEDURE
requested at cpcworldwide.com/MicroCNX
Seals: Silicone (clear), platinum-cured,
USP Class VI, ADCF PINCH CLICK PULL
Protective Cover: Polypropylene (teal), DID YOU KNOW
USP Class VI, ADCF
MicroCNX connectors eliminate the need to
Membrane: Hydrophobic Polyethersulfone, Cv values represent the approximate expected flow rate in gallons per
minute of water at room temperature for a 1 PSI pressure drop. The flow purchase, calibrate, validate, maintain, and
USP Class VI is generally constrained by the smallest diameter, which in some cases allocate clean room space for tube welding
will be the termination diameter and not the Nominal Flow Path.
STERILIZATION equipment.
Caution: CPC does not recommend the use of
Gamma: Up to 50kGy irradiation. PVC tubing with the polycarbonate MicroCNX™ Scan code to visit webpage
Autoclave: One cycle up to 266°F (130°C) Series Connectors. Leachables from PVC tubing
for 60 minutes could be incompatible with polycarbonate Remove the protective cover Join halves and click together. Pull membrane strips directly away
material and affect product performance. on each half. from the connector.
Determining product application suitability is
solely the customer’s responsibility. CPC does not
Caution: CPC does not recommend the use of PVC tubing with the polycarbonate MicroCNX™ Series Connectors. Leachables from PVC tubing could be incompatible with polycarbonate material and affect product performance. Determining product
guaranty or warrant product suitability for any application suitability is solely the customer’s responsibility. CPC does not guaranty or warrant product suitability for any application or use.
application or use.
SCAN
cpcworldwide.com/MicroCNX

14 cpcworldwide.com/bio · 1-800-444-2474 15 cpcworldwide.com/bio · 1-800-519-7633


ASEPTIC STERILE CONNECTION

ASEPTIQUIK CONNECTORS OPTIONS


WHAT IS ASEPTIQUIK® STERILE TECHNOLOGY? STERILIZATION FLOW
TERMINATIONS MATERIALS (CHOOSE 1) INFORMATION
AseptiQuik® Connectors provide quick and easy sterile connections, SANITARY

NE

TH
LE
HOSE BARB

LFO

PA
even in non-sterile environments–a critical capability for biopharmaceutical

TIB
FLANGES

ATE

E
U

G
W
L

E
PA
EA

YLS

AN
L

LO
ON

AB
OM
manufacturers. Featuring a straightforward, simple three-step connection

ES

ER
LF
B

EN

LAV
AC
AR
ON

LU
NA
H

OC
LYC

LYP
/2"

MM
IC
process and a wide range of termination options—including 1/8- to 1 1/2-inch

VA
"

MI
"

"

"

"

"

"
1/8

1/4

3/8

1/2

3/4

1/4

T
3/4

SIL
11

PO
1"

PO

NO
AU
GA

CV
sizes and genderless connections—the AseptiQuik series allows you to transfer ASEPTIQUIK® S
P P P P P P P P P 1/4" 0.19 – 1.74
media easily with less risk of error. Their robust, reliable performance eliminates SERIES
the need for clamps, fixtures or tube welders, giving you sterile, high-quality ASEPTIQUIK® G
P P P P P P P P P P 1/2" 1.5 - 31
single-use connections every time. SERIES
ASEPTIQUIK® G PPSU
P P P P P P P P 1/2" 1.5 - 31
SERIES
ASEPTIQUIK® L
P P P P P P P 1" 30-57
SERIES

FEATURES BENEFITS
Eases integration of single-use systems with
Genderless design universal mating between connectors of the same
series
ASEPTIQUIK CONNECTORS ASSEMBLY PROCEDURE
Rubust construction
Repeatable and reliable performance with no
additional hardware required FLIP CLICK
Innovative three-step connection process reduces risk
FLIP-CLICK-PULL
of operator error
Align the AseptiQuik
Pull tabs act as protective cover reducing part connector halves
Integrated pull tab covers complexity and ensure simultaneous removal of both
membranes with the pull tabs
hanging down.
CPC Click Audible confirmation of assembly Then, slide the two
Unsnap and flip halves together,
down the protective while independently
AQ AQ
pull tab covers on squeezing each side
NOMINAL FLOW PATH (NFP) SIZE
AQ

each AseptiQuik until you hear an


connector half. audible “CPC Click”.

PULL Scan code to watch


AseptiQuick assembly video
To complete the
connection, simply
snap the pull tabs
together by
pushing on the CPC
NFP CV RANGE NFP CV RANGE NFP CV RANGE
logos and pull the SCAN
AQS (0.25") 0.19 – 1.74 AQG (0.5") 1.5 – 30 AQG (1") 30 – 57 membranes from the
https://youtu.be/un2PnvUAZ0w
AseptiQuik connector
halves.
Cv values represent the approximate expected flow rate in gallons per minute of water at room temperature for a 1 PSI pressure drop. The flow is generally constrained
by the smallest diameter, which in some cases will be the termination diameter and not the NFP.

16 cpcworldwide.com/bio · 1-800-519-7633 17 cpcworldwide.com/bio · 1-800-519-7633


ASEPTIC STERILE CONNECTION
ASEPTIQUIK S SERIES DIMENSIONS

ASEPTIQUIK S ® POLYCARBONATE with blue pull tabs - For gamma irradiation applications.
TERMINATION METRIC EQ. PART NO. A B C

SERIES CONNECTORS 1/8" HOSE BARB

1/4" HOSE BARB


3.2 mm

6.4 mm
AQS17002

AQS17004
2.25" (57.2 mm)

2.25" (57.2 mm)


1.30" (33.0 mm)

1.45" (36.8 mm)


0.50" (12.7 mm)

0.65" (16.5 mm)

AseptiQuik® S Connectors provide quick and easy sterile connections 1/4" SANITARY 6.4 mm AQS33004 2.25" (57.2 mm) 1.50" (38.1 mm) 0.70" (17.8 mm)
for small-flow applications, even in non-sterile environments. The "FLIP- 3/8" HOSE BARB 9.5 mm AQS17006 2.25" (57.2 mm) 1.45" (36.8 mm) 0.65" (16.5 mm)
CLICK-PULL" design of AseptiQuik S enables users to easily transfer small
volumes of media with less risk of operator error than with traditional methods. 3/4" SANITARY 19.1 mm AQS33012 2.25" (57.2 mm) 1.60" (40.6 mm) 0.80" (20.3 mm)

The connector's genderless and robust design provides reliable performance MPC INSERT AQS17MPC 2.25" (57.2 mm) 1.49" (37.9 mm) 0.69" (17.5 mm)
without the need for clamps, fixtures or tube welders. Biopharmaceutical
manufacturers can now make 1/8", 1/4" and 3/8" hose barb and 1/4" and
3/4" sanitary sterile connections with the quality and market availability they
POLYCARBONATE HT with white pull tabs - For autoclave or gamma irradiation applications.
expect from the leader in single-use connection technology.
TERMINATION METRIC EQ. PART NO. A B C

SPECIFICATIONS 1/8" HOSE BARB 3.2 mm AQS17002HT 2.25" (57.2 mm) 1.30" (33.0 mm) 0.50" (12.7 mm)

FEATURES BENEFITS 1/4" HOSE BARB 6.4 mm AQS17004HT 2.25" (57.2 mm) 1.45" (36.8 mm) 0.65" (16.5 mm)
OPERATING PRESSURE Eases single-use systems specifications with one-
Up to 60 psi, 4.1 bar Genderless 1/4" SANITARY 6.4 mm AQS33004HT 2.25" (57.2 mm) 1.50" (38.1 mm) 0.70" (17.8 mm)
part number for both halves
Intuitive three-step connection process reduces risk 3/8" HOSE BARB 9.5 mm AQS17006HT 2.25" (57.2 mm) 1.45" (36.8 mm) 0.65" (16.5 mm)
OPERATING TEMPERATURE FLIP-CLICK-PULL
of operator error
39°F to 104°F (4°C to 40°C) 3/4" SANITARY 19.1 mm AQS33012HT 2.25" (57.2 mm) 1.60" (40.6 mm) 0.80" (20.3 mm)
Audible confirmation of connection with no
CPC Click MPC INSERT AQS17MPCHT 2.25" (57.2 mm) 1.49" (37.9 mm) 0.69" (17.5 mm)
additional hardware required
STERILIZATION
Gamma: Up to 50kGy irradiation Enables the ability to change a BPC or other single-
or AQS-MPC Combination use system with open format connections to closed
AutoClave High Temp (HT) Version: systems
Up to 266°F (130°C) for 60 minutes PRODUCT DIMENSIONS
Minimizes transitional flow disruptions throughout
AQS ¼" Sani with Smooth Bore
upstream processing
TERMINATIONS C C

1/8", 1/4" and 3/8" ID hose barb (3.2mm,


6.4mm and 9.5mm), 1/4" and 3/4" sanitary
and MPC insert A = Height/Diameter
TYPICAL FLOW RATE:
Cv Value Range: 0.19 - 1.74
NOTE A A
B = Total Length
MATERIALS Validation and Extractables data can be C = Hose Barb Length
for AseptiQuik S
Main Components: requested at cpcworldwide.com/AseptiQuik-S
Polycarbonate (white)
Pull Tabs/Caps: B B

Polycarbonate (blue, standard version)


Polycarbonate (white, HT version) Cv values represent the approximate expected flow rate in gallons per
DID YOU KNOW
Seals: minute of water at room temperature for a 1 PSI pressure drop. The flow Did you know that the AseptiQuik S is perfect
is generally constrained by the smallest diameter, which in some cases
for simplifying the process to pull flask
Silicone (clear), platinum-cured
Membrane:
will be the termination diameter and not the Nominal Flow Path.
samples from your bioreactor? NOTES
Polyethylene (standard version)
Hydrophobic polyethersulfone (HT version), Scan code to visit webpage
PTFE strip sticker

WARNING: Pressure, temperature, chemicals, and operating environment can


affect the performance of couplings. It is the customer’s responsibility to test
the suitability of CPC’s products in their own application conditions.

SCAN

cpcworldwide.com/AseptiQuik-S

18 cpcworldwide.com/bio · 1-800-519-7633 19 cpcworldwide.com/bio · 1-800-519-7633


ASEPTIC STERILE CONNECTION
ASEPTIQUIK G SERIES DIMENSIONS

ASEPTIQUIK G ® POLYCARBONATE with blue pull tabs - For gamma irradiation applications.
TERMINATION METRIC EQ. PART NO. A B C

SERIES CONNECTORS 1/4" HOSE BARB

3/8" HOSE BARB


6.4 mm

9.5 mm
AQG17004

AQG17006
2.62" (66.6 mm)

2.62" (66.6 mm)


1.62" (41.2 mm)

1.62" (41.2 mm)


0.82" (20.8 mm)

0.82" (20.8 mm)

AseptiQuik® G Connectors enable quick and easy sterile connections, 1/2" HOSE BARB 12.7 mm AQG17008 2.62" (66.6 mm) 1.95" (49.5 mm) 1.15" (29.2 mm)
even in non-sterile environments. The easy-to-use genderless design simplifies
3/4" HOSE BARB 19.1 mm AQG17012 2.62" (66.6 mm) 2.36" (59.9 mm) 1.56" (39.6 mm)
system integration and minimizes the risk of operator error. The connectors' robust
construction provides enhanced user confidence and reliable performance without 3/4" SANITARY 19.1 mm AQG33012 2.62" (66.6 mm) 1.66" (42.2 mm) 0.86" (21.8 mm)

the need for clamps, fixtures or tube welders. Biopharmaceutical manufacturers 1-1/2" SANITARY 38.1 mm AQG33024 2.62" (66.6 mm) 2.86" (72.6 mm) 2.02" (51.3 mm)
benefit from a full range of interchangeable 1/4" to 1-1/2" termination solutions
with the quality and market availability they expect from the leader in single-use
connection technology.
POLYCARBONATE HT with white pull tabs - For autoclave or gamma irradiation applications.
TERMINATION METRIC EQ. PART NO. A B C

SPECIFICATIONS FEATURES BENEFITS 1/4" HOSE BARB 6.5 mm AQG17004HT 2.62" (66.6 mm) 1.62" (41.2 mm) 0.82" (20.8 mm)

Eases single-use systems specifications with one- 3/8" HOSE BARB 9.5 mm AQG17006HT 2.62" (66.6 mm) 1.62" (41.2 mm) 0.82" (20.8 mm)
OPERATING PRESSURE Genderless
part number for both halves
Up to 60 psi, 4.1 bar 1/2" HOSE BARB 12.7 mm AQG17008HT 2.62" (66.6 mm) 1.95" (49.5 mm) 1.15" (29.2 mm)
Intuitive three-step connection process reduces risk
Up to 75 psi, 5.1 bar for 48 hours FLIP-CLICK-PULL
of operator error 3/4" HOSE BARB 19.1 mm AQG17012HT 2.62" (66.6 mm) 2.36" (59.9 mm) 1.56" (39.6 mm)
Audible confirmation of connection with no
OPERATING TEMPERATURE CPC Click
additional hardware required
3/4" SANITARY 19.1 mm AQG33012HT 2.62" (66.6 mm) 1.66" (42.2 mm) 0.86" (21.8 mm)
34°F to 104°F (1°C to 40°C)
AseptiQuik PPSU enables genderless connection for 1-1/2" SANITARY 38.1 mm AQG33024HT 2.62" (66.6 mm) 2.86" (72.6 mm) 2.02" (51.3 mm)
a greater range of chemical applications, offering
STERILIZATION Chemical Compatibility and pH Range
versatile connections across downstream processes
Standard (blue) and PPSU (purple) Version: with a pH range from 2 to 12
Gamma: up to 50kGy POLYPHENYLSULFONE with purple pull tabs - For gamma irradiation applications.
AseptiQuik PPSU meets a broader range of
High Temperature (white) Version: BPA-free
Application Requirements TERMINATION METRIC EQ. PART NO. A B C

or
Gamma: up to 50kGy
1/4" HOSE BARB 6.4 mm AQG17104 2.62" (66.6 mm) 1.62" (41.2 mm) 0.82" (20.8 mm)
Autoclave:
One cycle up to 266°F (130°C) for 60 minutes 3/8" HOSE BARB 9.5 mm AQG17106 2.62" (66.6 mm) 1.62" (41.2 mm) 0.82" (20.8 mm)

TERMINATIONS 1/2" HOSE BARB 12.7 mm AQG17108 2.62" (66.6 mm) 1.95" (49.5 mm) 1.15" (29.2 mm)

1/4", 3/8", 1/2", 3/4" ID hose barb (6.4mm, 9.5mm,


TYPICAL FLOW RATE:
Cv Value Range: 1.5 - 31
NOTE 3/4" HOSE BARB 19.1 mm AQG17112 2.62" (66.6 mm) 2.36" (59.9 mm) 1.56" (39.6 mm)
12.7mm, 19.0mm) and 3/4", 1-1/2" sanitary Validation and Extractables data can be
for AseptiQuik G requested at cpcworldwide.com/AseptiQuik-G 3/4" SANITARY 19.1 mm AQG33112 2.62" (66.6 mm) 1.66" (42.2 mm) 0.86" (21.8 mm)

MATERIALS
Main Components:
Polycarbonate (white), (standard and HT versions) DID YOU KNOW
Polyphenylsulfone (off white) (PPSU version) Cv values represent the approximate expected flow rate in gallons per Did you know that the AseptiQuik G is perfect
Pull Tabs/Caps: minute of water at room temperature for a 1 PSI pressure drop. The flow for connecting different buffers to your
is generally constrained by the smallest diameter, which in some cases
Polycarbonate (blue, standard), (white, HT will be the termination diameter and not the Nominal Flow Path. chromatography skid? PRODUCT DIMENSIONS
version), (purple, PPSU version)
Seals: Scan code to visit webpage C C

Silicone (clear), platinum-cured


A = Height/Diameter
Membranes:
B = Total Length
Polyethylene (standard and PPSU versions), A A
C = Hose Barb Length
Hydrophobic polyethersulfone (HT version),
PTFE strip sticker
WARNING: Pressure, temperature, chemicals, and operating environment can SCAN
affect the performance of couplings. It is the customer’s responsibility to test B B
the suitability of CPC’s products in their own application conditions.
cpcworldwide.com/AseptiQuik-G

20 cpcworldwide.com/bio · 1-800-519-7633 21 cpcworldwide.com/bio · 1-800-519-7633


ASEPTIC STERILE CONNECTION
ASEPTIQUIK L SERIES DIMENSIONS

ASEPTIQUIK L ® Polycarbonate with blue pull tabs - For gamma irradiation applications.

TERMINATION METRIC EQ. PART NO. A B C

SERIES CONNECTORS 3/4" HOSE BARB

1" HOSE BARB


6.4 mm

25.4 mm
AQL17012

AQL17016
4.22" (107.2 mm)

4.22" (107.2 mm)


2.95" (74.9 mm)

3.15" (80.0 mm)


1.50" (38.1 mm)

1.70" (43.2 mm)

AseptiQuik® L Connectors enable quick and easy sterile 1-1/2" SANITARY 38.1 mm AQL33024 4.22" (107.2 mm) 3.40" (86.4 mm) 1.95" (49.5 mm)
connections, in large-volume, high-flow production environments. The
large-format, 3/4", 1" hose barb and 1-1/2" sanitary genderless design
simplifies system integration and minimizes the risk of operator error.
The connectors' robust construction provides reliable performance
without the need for clamps, fixtures or tube welders. Biopharmaceutical Polycarbonate HT with white pull tabs - For autoclave or gamma irradiation applications.
manufacturers benefit from the interchangeable connection sanitary flow
solutions for full-scale bioprocessing production environments with the TERMINATION METRIC EQ. PART NO. A B C

quality and market availability they expect from the leader in single-use 3/4" HOSE BARB 6.4 mm AQL17012HT 4.22" (107.2 mm) 2.95" (74.9 mm) 1.50" (38.1 mm)
connection technology.
1" HOSE BARB 25.4 mm AQL17016HT 4.22" (107.2 mm) 3.15" (80.0 mm) 1.70" (43.2 mm)

1-1/2" SANITARY 38.1 mm AQL33024HT 4.22" (107.2 mm) 3.40" (86.4 mm) 1.95" (49.5 mm)

SPECIFICATIONS
FEATURES BENEFITS PRODUCT DIMENSIONS
OPERATING PRESSURE
Up to 60 psi, 4.1 bar Eases single-use systems specifications with one- B
Genderless
part number for both halves
Up to 75 psi, 5.1 bar for 48 hours
Intuitive three-step connection process reduces risk
FLIP-CLICK-PULL
OPERATING TEMPERATURE of operator error A = Height/Diameter
34°F to 104°F (1°C to 40°C) CPC Click
Audible confirmation of connection with no B = Total Length
additional hardware required A
C = Hose Barb Length
STERILIZATION Fast and efficient fluid transfer of large volumes
Large Internal Diameter
or
Gamma: Up to 50kGy irradiation under low pressures
Autoclave High Temp (HT) Version:
Up to 266°F (130°C) for 60 minutes C

TERMINATIONS TYPICAL FLOW RATE:


Cv Value Range: 30 - 57
3/4", 1" ID hose barb (19.0 mm, 25.4 mm)
and 1-1/2" sanitary for AseptiQuik L NOTE
Validation and Extractables data can be
MATERIALS requested at cpcworldwide.com/AseptiQuik-L
Main Components:
Polycarbonate (white)
Cv values represent the approximate expected flow rate in gallons per
Pull Tabs/Caps:
Polycarbonate (blue, standard version)
minute of water at room temperature for a 1 PSI pressure drop. The flow
is generally constrained by the smallest diameter, which in some cases
will be the termination diameter and not the Nominal Flow Path.
DID YOU KNOW
Polycarbonate (white, HT version) Did you know that the AseptiQuik L is perfect
Seals: for connecting TFF, TFDF, and ATF and other
Scan code to visit webpage
Silicone (clear), platinum-cured filtration processes that require large flow
Membranes: volumes?
Polyethylene (standard version)
Hydrophobic polyethersulfone (HT version),
PTFE strip sticker
WARNING: Pressure, temperature, chemicals, and operating environment can
affect the performance of couplings. It is the customer’s responsibility to test
SCAN
the suitability of CPC’s products in their own application conditions.
cpcworldwide.com/AseptiQuik-L https://www.cpcworldwide.com/Blog/post/how-to-choose-sterile-connectors

22 cpcworldwide.com/bio · 1-800-519-7633 23 cpcworldwide.com/bio · 1-800-519-7633

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