Nature

ACLF

Acuteinsult Chronicinjury
•Ethanol •Chronicliver
disease
•HepatitisBreactivation
•Viralhepatitis •Cirrhosis
•Autoimmunehepatitis •Asymptomatic
king's college hospital meld
•Compensated
•Drug-inducedliverinjury
•Wilson'sdiseaseflare •Noprior
decompensation
•Unknown

Liverfailure
•laundice
•Coagulopathy
•Ascitesorhepaticencephalopathy

Reversibility
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NatureReviews|Gastroenterology&Hepatology

Acute-on-chronic liver Visit

failure: terminology,…
mechanisms
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