GENERIC NAME MECHANISM OF ACTION SIDE EFFECTS NURSING RESPONSIBILITY

OMEPRAZOLE Inhibits hydrogen-potassium Frequent: Headache  Evaluate for therapeutic

adenosine triphosphatase , an Occasional: Diarrhea, abdominal pain, response. Question if GI
enzyme on the surface of gastrix nausea discomfort, nausea, or diarrhea
parietal cells. Increasing gastric pH, Rare: Dizziness, asthenia, vomiting, occurs.
and reduces gastric acid production. constipation, upper respiratory tract  Report headache, the onset of
BRAND NAME INDICATION infection, back pain, rash, cough. black, tarry stools, diarrhea,
Short-term treatment of erosive and abdominal pain.
PROSEC esophagitis, symptomatic  Educate the patient to avoid
gastroesophageal reflux, poorly alcohol.
responsive to other treatment.
Treatment of frequent uncomplicated
heartburn occurring 2 or more
days/week. Prevention of NSAID-
induced ulcers, stress ulcer
prophylaxis in critically ill pts.
DRUG ILLUSTRATION CONTRAINDICATION ADVERSE REACTION
 Hypersensitivity to omeprazole, Pancreatitis, hepatotoxicity, interstitial
other proton pump inhibitors. nephritis, and increased risk of
 Concomitant use with products Clostridioides difficile infection
containing rilpivirine.
 Increase risk of fractures, GI
infection, hepatic impairment of
CLASSIFICATION patients of Asian descent.
Pharmacotherapeutic:
BENZIMIDAZOLE
CLINICAL: Proton pump inhibitor

DOSAGE/FREQUENCY/ ROUTE
Route: IV infusion
Frequency: q24 hrs
Dosage: 40 mg

GENERIC NAME MECHANISM OF ACTION SIDE EFFECTS NURSING RESPONSIBILITY

 ACETAMINOPHEN Analgesics activates descending  Hypersensitivity reaction Baseline Assessment:
serotonergic inhibitory pathways in  Rash  Assess onset, type, location,
CNS. Antipyretic inhibits  Nausea duration of pain.
hypothalamic heat regulating center.  Stomach pain  Assess for fever
BRAND NAME INDICATION  Headache
TYLENOL It is used to temporarily relied mild to  Hoarseness Intervention:
moderate pain, headache, and fever.  Loss of Appetite  Assess for clinical
improvement and relief of pain,
and fever.
 Acetaminophen can cause
hematologic reactions. Monitor
DRUG ILLUSTRATION CONTRAINDICATION ADVERSE EFFECTS for anemia and decreased red
 Hypersensitivity to Early signs of Acetaminophen and white blood counts.
acetaminophen, severe Toxicity: Anorexia, nausea,  Educate the patient not to take
hepatic impairment or severe diaphoresis, fatigue within first 12-24 acetaminophen together with
active liver disease. hrs. warfarin as it can increase the
risk of bleeding.
Later signs: Vomiting, right upper
CLASSIFICATION quadrant tenderness, elevated LFTs
Pharmacotherapeutic: Central
Analgesic
Clinical: Non-narcotic analgesic,
antipyretic

DOSAGE/FREQUENCY/ ROUTE
Route: Oral
Frequency: 1 Tab prn
Dosage: 500 mg

Reference:
Kizior, R. J., & Hodgson, K. J. (2021). Saunders nursing drug handbook 2021 / Robert J. Kizior, Keith J. Hodgson. Elsevier.
https://www.nursetogether.com/acetaminophen-nursing-considerations/