Dilated Cardiomyopathy (DCM):

1. What is the most frequent type of cardiomyopathy? a. Hypertrophic cardiomyopathy b.

Dilated cardiomyopathy c. Restrictive cardiomyopathy d. Arrhythmogenic cardiomyopathy

2. Which sarcomeric protein is associated with DCM? a. Troponin b. Dystrophin c. Myosin-

binding protein C d. Titin

3. What percentage of the general population is affected by DCM? a. 0.01% b. 0.04% c. 0.1%
d. 1%

4. Which gene mutation is most commonly associated with DCM? a. MYH7 b. SCN5A c. TTN d.
MYBPC3

5. What is the primary pathophysiological characteristic of DCM? a. Left ventricular

hypertrophy b. Right ventricular dilation c. Progressive severe systolic dysfunction d.
Increased coronary artery diameter

6. Which gene mutation is associated with the RNA binding protein 20 in DCM? a. MYH7 b.
RBM20 c. MYBPC3 d. SCN5A

7. What is the role of connexin 43 in DCM? a. Muscle contraction b. Sodium ion influx c. Cell
membrane stabilization d. Gap junction formation

8. Which clinical examination finding is not commonly associated with DCM? a. S3-S4 b.
Tachyarrhythmias c. Hypertension d. Severe mitral regurgitation

9. What ECG abnormality is commonly seen in DCM? a. Right bundle branch block (RBBB) b.
Left anterior fascicular block c. Atrial fibrillation d. Atrioventricular block

10. Which genetic factor is associated with 90% of familial cases of DCM? a. MYH7 mutation b.
TTN mutation c. LMNA mutation d. RBM20 mutation

Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC):

11. Which desmosomal protein is involved in structural stability in ARVC? a. Titin b.

Desmoplakin c. Plakoglobin d. Myopalladin

12. What is the characteristic ECG pattern seen in ARVC? a. Left bundle branch block (LBBB) b.
Right bundle branch block (RBBB) c. Atrial fibrillation d. Pseudo-infarction pattern

13. In ARVC, what is the typical location known as the "triangle of dysplasia"? a. Left
ventricular outflow tract b. Right ventricular outflow tract c. Postero-inferior wall of RV d.
Antero-lateral wall of LV

14. Which stage of ARVC is characterized by severe RV dilation and aneurysm formation? a.
Subclinical, early b. Severe RV dilation c. Malignant ventricular arrhythmias d. Triangle of
dysplasia

15. What is the treatment strategy for ARVC? a. ACE inhibitors b. Diuretics c. Cardiac
transplantation d. Anti-arrhythmics and catheter ablation
Restrictive Cardiomyopathy (RCM):

16. What is the primary characteristic of RCM? a. Left ventricular hypertrophy b. Diastolic
dysfunction c. Systolic dysfunction d. Right ventricular dilation

17. Which condition is NOT commonly associated with non-infiltrative RCM? a. Scleroderma b.
Idiopathic RCM c. Fabry's disease d. Pseudoxanthoma elasticum

18. Which imaging modality is useful for diagnosing RCM? a. CT scan b. MRI c. X-ray d. PET scan

19. What is the typical pattern of the diastolic pressure curve in RCM? a. Dip and plateau b.
Sawtooth pattern c. Rapid decline d. Square-root sign

20. What is the key difference between RCM and constrictive pericarditis? a. LV wall thickness
b. Diastolic A-V pressure difference c. Presence of QRS amplitude d. Pulmonary hypertension

21. Which condition is NOT a common cause of infiltrative RCM? a. Amyloidosis b. Sarcoidosis
c. Hemochromatosis d. Endomyocardial fibrosis

Cardiac Amyloidosis:

22. Which type of amyloidosis is associated with fibrils composed of light chains of
immunoglobulin? a. ATTR b. AL c. AA d. Aβ

23. What is the primary treatment goal in cardiac amyloidosis? a. Liver transplantation b.
Chemotherapy c. Diuretics d. ACE inhibitors

24. Which imaging modality is used to assess myocardial involvement in amyloidosis? a. X-ray
b. Echocardiography c. CT scan d. PET scan

25. Which medication is contraindicated in cardiac amyloidosis due to its high affinity for
amyloid fibers? a. Beta-blockers b. Diuretics c. ACE inhibitors d. Digitalis

26. What is the most common clinical consequence of cardiac amyloidosis? a. Dilated
cardiomyopathy b. Restrictive cardiomyopathy c. Hypertrophic cardiomyopathy d.
Arrhythmogenic cardiomyopathy

Other Cardiomyopathies:

27. Which cardiomyopathy is specific to temperate climates and is associated with

eosinophilia? a. Hypertrophic cardiomyopathy b. Loeffler endocarditis c. Non-compaction
cardiomyopathy d. Stress-induced cardiomyopathy

28. Which region is specifically associated with endomyocardial fibrosis? a. Temperate climates
b. Tropical regions c. Arctic regions d. Polar regions

29. What is the characteristic feature of endomyocardial fibrosis on histology? a. Infiltration

with eosinophils b. Amyloid fibrils c. Fibrosis in the apical and sub-valvular regions d.
Thrombotic necrosis

30. Which treatment is NOT commonly used in endomyocardial fibrosis? a. Corticosteroids b.

Hydroxyurea c. Heart transplantation d. Chemotherapy

Answers:

1. b, 2. d, 3. b, 4. c, 5. c, 6. b, 7. d, 8. c, 9. a, 10. c,
2. c, 12. b, 13. d, 14. c, 15. c, 16. b, 17. c, 18. b, 19. a, 20. b,

3. d, 22. b, 23. b, 24. b, 25. d, 26. b, 27. b, 28. b, 29. c, 30. d.