Professional Documents
Culture Documents
Omeprazole 2
Omeprazole 2
Omeprazole 2
1. Peptic ulcer
2. GERD
3. H pylori infection
4. NSAID induced ulcer
5. Reflux esophagitis
6. Zollinger-Ellison syndrome
7. Prophylaxis for ulcers
Uses
• GERD:
– <1 year: Safety and efficacy not established
– 5-10 kg: 5 mg PO qDay
– 10-20 kg: 10 mg PO qDay
– >20 kg: 20 mg PO qDay
Uses
• Erosive Esophagitis
• <1 month: Safety and efficacy not established
• Aged 1 month to <1 year
• 3 to <5 kg: 2.5 mg qDay
• 5 to <10 kg: 5 mg qDay
• ≥10 kg: 10 mg qDay
• May treat for up to 6 weeks
• Aged 1-16 years
• 5 to <10 kg: 5 mg PO qDay
• 10 to <20 kg: 10 mg PO qDay
• ≥20 kg: 20 mg PO qDay
• May treat for 4-8 weeks
Adverse Effects
• Headache (7%)
• Abdominal pain (5%)
• Diarrhea (4%)
• Nausea (4%)
• Vomiting (3%)
• Flatulence (3%)
• Dizziness (2%)
• Upper respiratory infection (2%)
• Acid regurgitation (2%)
• Constipation (2%)
• Rash (2%)
• Cough (1%)