Number 2, August 1979

ARTICLES
Clinical Indicators of Left Main Coronary Artery Disease in Unstable Angina. G. D. Plotnick, H. L Green, N.H.
Carliner, L C. Becker, and M. L. Fisher 149
Reactive Hyperreninemia in Renovascular Hypertension After Angiotensin Blockade with Saralasin or Converting
Enzyme Inhibitor. D. B. Case and J. H. Laragh 153
Ventriculoatrial Intervals: Diagnostic Use with Paroxysmal Supraventricular Tachycardia. D. G. Benditt, E. L. C.
Pritchett, W. M. Smith, and J. J. Gallagher 161
Infection Due to Corynebacterium Species in Marrow Transplant Patients. W. E. Stamm, L. S. Tompkins K. F.
Wagner, G. W. Counts,t E. D. Thomas, and J. D. Meyers 167
Safety of Changing Intravenous Delivery Systems at Longer than 24-Hour Intervals. J. D. Band and D. G. Maki 173
Campylobacter Enteritis: Clinical and Epidemiologic Features. M. J. Blaser, I. D. Berkowitz, F. M. LaForce, J. Cra-
vens, L. B. Reller, W. L. L Wang 179
Autoantibodies and the Spectrum of Sjogren's Syndrome. M. Martinez-Lavin, J. H. Vaughan, andE. M. Tan 185
The Chronicity of Symptoms and Disability in Reiter's Syndrome. R. Fox, A. Calin, and R. C Gerber 190
Immunologic and Coagulation Disorders in Chlorpromazine-Treated Patients. M. H. Zarrabi, S. Zucker, F. Miller,
and R. M. Derman 194
Hyperamylasemia in Diabetic Ketoacidosis: Sources and Significance. F. Vinicor, L M. Lehrner, R. C. Karn, and A. D.
Merritt 200

SHORT PAPERS
Obstruction of the Proximal Right Coronary Artery with Acute Inferior Infarction Due to Blunt Chest Trauma. P. B.
Oliva, A. Hilgenberg, andD. McElroy 205
Pheochromocytoma Associated with Hypercalcemia and Ectopic Secretion of Calcitonin. H. Heath III and A. J. Edis .. 208
Prolactin-Secreting Tumors in Men: Surgical Cure. A. Pont, R. Shelton, W. D. Odell, and C B. Wilson 211
Amino Acid Deficiency and the Skin Rash Associated with Glucagonoma. J. A. Norton, C. R. Kahn, R. Schiebinger, C
Gorschboth, and M. F. Brennan 213
Hereditary C2 Deficiency with Common Variable Immunodeficiency. M. Seligmann, J. C. Brouet, and M. Sasportes . . . 216
Hemodialysis in the Treatment of Psoriasis. A. R. Nissenson, M. Rapaport, A. Gordon, and R. G. Narins 218
Bladder Complications in Patients Receiving Cyclophosphamide for Systemic Lupus Erythematosus or Rheuma-
toid Arthritis. P. H. P/otz, J. H. Klippel, J. L Decker, D. Grauman, B. Wolff, B. C. Brown, and G. Rutt 221

BRIEF REPORTS
Flagella on Legionnaires' Disease Bacteria: An Interim Report. B. M. Thomason, F. W. Chandler, andD. G. Hollis 224
Case-Control Study of Oral Contraceptive Pills and Endometrial Cancer. R. I. Horwitz and A. R. Feinstein 226
Massive Amikacin "Overdose." P. W. L Ho, F. D. Pien, andN. Kominami 227
Hairy-Cell Leukemia Presenting as Aplastic Anemia. R. L Brearley, R. M. Chapman, andB. Brozovic 228

DIAGNOSIS AND TREATMENT

New Drugs: Bretylium Tosylate: A Newly Available Antiarrhythmic Drug for Ventricular Arrhythmias. R. H Heissen-
butteland J. T. Bigger Jr. 229

NIH CONFERENCE
Basic and Clinical Studies of Endorphins. W. E. Bunney Jr., C B. Pert, W. Klee, E. Costa, A. Pert, and G. C. Davis 239

REVIEW
Multimodal Primary Cancer Treatment (Adjuvant Chemotherapy): Current Results and Future Prospects. R. B.
Weiss and V. T. DeVita Jr. 251

BASIC REVIEW
Fever: Pathogenesis, Pathophysiology, and Purpose. H. A. Bernheim, L. H. Block, and E. Atkins 261

ACADEMIA AND CLINIC

The Effect of a Primary-Care Pathway on Internal Medicine Residents' Career Plans. D. L. Goldenberg, J. T. Pozen,
and A. S. Cohen 271

MEDICINE AND PUBLIC ISSUES

A National Study of Internal Medicine and Its Specialties: II. Primary Care in Internal Medicine. R. C. Mendenhall,
A. R. Tarlov, R. A. Girard, J. K. Michel, andS. E. Radecki 275
National Study of Internal Medicine Manpower: III. Subspecialty Fellowship Training 1 9 7 6 - 1 9 7 7 . A. R. Tarlov, P. A.
Weil, M. K. Schleiter, and The Association of Professors of Medicine Task Force on Manpower 287
National Study of Internal Medicine Manpower: IV. Residency and Fellowship Training 1 9 7 7 - 1 9 7 8 and 1978-
1979. A. R. Tarlov, M. K. Schleiter, P. A. Weil, and The Association of Professors of Medicine Task Force on
Manpower 295

PERSPECTIVE
Hemoperfusion to Treat Intoxications. J. A. Lorch and S. Garella 301

Contents continued on next page

Annals of Internal Medicine • Volume 91 vii
 Contents continued from page vii

EDITORIALS AND EDITORIAL NOTES Splenectomy in Sickle-Cell Disease 320

The Place of the General Internist in Primary P. W. Wilson, W. R. Berry, and W. F. Rosse
Care. M. L Peterson 305 Ftenal Excretion of Technetium-99m Diphospho-
Internal Medicine Manpower: Trends in Training nate in Osteomalacia 320
Programs and Policy Implications. P. R. Lee /. Fogelman and R. G. Bessent
andL. B. LeRoy 307 Danazol and Thyroid Function 321
Importance of Identifying Left Main Coronary Ar- J. Worts man, J. Hirschowitz, and N. Soler
tery Narrowing in Subsets of Patients with Cor- Adrenocorticotropin (ACTH) Test and
onary Artery Disease. S. E. Epstein 308 Hyponatremia 321
New Light on the Insulin Controversy. R. P. L. I. Rose
Hudson 311 Spironolactone and Metabolic Acidosis 321
At Your Pleasure. The Editor 312 D. W. Nierenberg; P. A. Gabow, S. Moore, and R.
W. Schrier
AD LIBITUM Stretococcal Pharyngitis and Gram Stains 322
The Pile of Paper on the Professor's Desk. G. R. A. Wright and E. N. Scho/es; G. Crawford
Dunea 313 Legionella pneumophila in Drinking Water of
Guinea Pigs 323
Under the Crystal Eye. B. Z. Paulshock 313
R. W. Connor and D. N. Gilbert
Treatment of Aspergillosis in Leukemia 323
LETTERS B. A. Adelman, A. Bentman, P. Rosenthal, B. R.
Nuclear Power and Health 314 Smith, K. R. Bridges, and W. Holmes
H. R. Maxon; L R. Solon and V. W. Side/ Ocular Toxoplasmosis 324
Training the Internist 315 R. P. Handler
J. A. Barondess; W. B. Bateman, Jr., H. G. Ampicillin Rash and Hyperuricemia 324
Bloom, and J. I. Boufford T. F. Murphy
Immunity in Hodgkin's Disease 316 Medical Education in Colombia 325
N. Gutensohn and P. Cole; N. J. Vianna A. F. Jacome-Roca
Cimetidine, Lupus Erythematosus, and Library Resources on Alcoholism 325
Granulocytopenia 317 D. M. Novick and S. R. Yancovitz
G. O. Littlejohn and M. B. Urowitz
Irritable Bowel Syndrome 317 THE LITERATURE OF MEDICINE
W. G. Thompson and K. W. Heaton Searching the Literature and Computerized Serv-
Intravascular Coagulation and Ascitic-Fluid ices in Medicine. W. K. Beatty 326
Infusion 318 Pulmonary Diseases: An Annotated Bibliography
A. Viallet and J. P. Villeneuve; W. M. Lee of Recent Literature 333
Potassium Tolerance in Sickle-Cell Book Reviews and Notices 338
Hemoglobinopathy 319 Information for Authors 1-6
P. Mitnick, R. Sterns, and M. Cox Copyright Form 1-37

vjjj Annals of Internal Medicine • Volume 91