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Lecture 4
Lecture 4
Lecture 4
Nasal Cavity
• The surface of the lateral parts of the nasal
cavity is thrown into folds by bony projections
called conchae. These folds increase the
surface area of the nasal cavity and create
turbulence in the stream of passing air, both of
which facilitate the conditioning (warming,
cooling and filtration) of the air. Mucous and
serous glands in the connective tissue
underlying the epithelium, the lamina propria,
supplement the secretion of the goblet cells.
Veins in the lamina propria
Transition of cartilage
• Trachea C-ring cartilages
• Main Bronchi Complete Ring
• Secondary Bronchi Complete Ring
• Tertiary Bronchi Platelet
• Terminal Bronchi No cartilage
Cartilage Platelets
Transition of Epithelium
• Trachea Ciliated pseudostratified
3
• Main Bronchi Ciliated pseudostratified
2
1 5
• Secondary Bron. Ciliated pseudostratified
• Tertiary Bronchi Ciliated pseudostratified
•
8 4
Terminal Bronchi Ciliated & non-ciliated
6 • Respiratory Alveolar 1 & 2
Organ? 40X
Alveolar Cells
Alveolar Duct
• Alveolar type I cells (small alveolar cells or type I
pneumocytes) are extremely flattened (the cell may be
as thin as 0.05 µm) and form the bulk (95%) of the
surface of the alveolar walls.
• Alveolar type II cells (large alveolar cells or type II
pneumocytes) are irregularly (sometimes cuboidal)
shaped. They form small bulges on the alveolar walls.
Type II alveolar cells contain large number of granules
called cytosomes (or multilamellar bodies), which
consist of Precursors To Pulmonary Surfactant (the
mixture of phospholipids which keep surface tension
in the alveoli low) . There are less type II cells than
type I cells. But since Type I are smaller in size we
see more type I in one focus of the section.
fusion of basement membrane lungs and kidneys Clinical Application
• Newborn respiratory distress
syndrome (NRDS) happens
when a baby's lungs are
not fully developed and
cannot provide enough
oxygen, causing breathing
difficulties. It usually affects
premature babies. It's also
known as infant respiratory
distress syndrome
EMPHYSEMA
• Destructive of the alveoli and terminal bronchioles
• Loss of elasticity of smaller airways
• Loss of patency of bronchioles