CLONING METHODS OF ORGANISMS

Learning Objectives:

11.4.3.3 Understand the principles and methods of cloning in organisms.

11.4.3.3 Compare and contrast different cloning techniques.

Assessment Criteria:
A learner
 Demonstrates understanding of cloning principles and methods.
 Compares and contrasts different cloning techniques.

Level of Thinking Skills:

Application and Analysis

Tasks:

1. Figure 1 shows the process of somatic cell nuclear transfer (SCNT) in

cloning.

Figure 1

Describe the key steps involved in somatic cell nuclear transfer (SCNT) and
explain its significance in cloning.

2. Distinguish between reproductive cloning and therapeutic cloning. Provide

examples of each.

3. Identify the advantages and disadvantages of using recombinant DNA

technology in cloning. Support your response with specific examples.
 4. Consider the ethical implications of cloning. Discuss potential ethical
concerns associated with the use of cloning techniques in organisms.

Descriptors:
A learner
 Describes the key steps involved in somatic cell nuclear transfer
(SCNT).
 Differentiates between reproductive and therapeutic cloning,
providing accurate examples.
 Identifies advantages and disadvantages of using recombinant DNA
technology in cloning, supported by examples.
 Discusses ethical concerns associated with cloning, demonstrating an
understanding of the implications.

Mark Scheme:
Task Descriptor Marks
1 Describes SCNT steps and significance 5
2 Clearly distinguishes between reproductive and therapeutic 5
cloning with examples
3 Identifies advantages and disadvantages of recombinant DNA 5
technology in cloning with examples
4 Discusses ethical concerns associated with cloning 5
IMMUNE SYSTEM
Learning Objective:
11.4.1.1 Understand the interaction between the antigen and the antibody.

Assessment Criteria:
A learner
 Describes the process of antigen-antibody interaction.
 Identifies the correct mechanisms involved in the immune response.

Level of Thinking Skills:

Application

Tasks:
1. Figure below shows an antibody binding to an antigen.

Describe the process of antigen-antibody interaction, highlighting the key steps

involved.

2. In the immune response, which of the following statements is correct

regarding the role of antibodies?
A. Activation of phagocytes
B. Neutralization of toxins
C. Complement activation
D. All of the above
Choose the correct option and provide a brief explanation for your choice.

3. Explain how the immune system distinguishes between self and non-self
antigens.

Descriptors:
A learner
  Describes the process of antigen-antibody interaction, highlighting key
steps.
 Chooses the correct option and provides a brief explanation.
 Explains how the immune system distinguishes between self and non-self
antigens.

Mark Scheme:
Task 1: Descriptive response highlighting the key steps of antigen-antibody
interaction. (10 marks)
Task 2: Correctly choosing the option (1 mark) and providing a brief explanation
(5 marks).
Task 3: Explanation of how the immune system distinguishes between self and
non-self antigens. (8 marks)