in this lesson we will talk about semi-solid dosage forms properties that compose a semi-solid

dosage form 1 physical properties A smooth texture B elegant in appearance C non dehydrating D
non-gritty E non greasy and non-staining 2 physiological properties A non irritating B do not alter
membrane or skin functioning C visible with skin secretion D have low sensitization effect 3
application properties A easily applicable with a fishing drug release B High acreage washability
now let's explore the advantages and disadvantages of semi-solid dosage forms.

The advantages 1 using somi-solid dosage forms avoids first pass metabolism 2 semi-solid offer a
site specific action of drug on the affected area 3 they are convenient for unconscious patients 4
their suitable dosage forms for bitter drugs 5 they're more stable than liquid dosage forms.

The disadvantages 1 they may cause staining 2 they're bulky to handle 3 application with finger
may cause contamination of the product 4 semi-solid are less stable than solid dosage forms 5 they
may cause irritation 5 so patients are allergic to semi-solid preparations.

Semi-solid solid dosage forms are mainly classified into six forms 1 creams creams are
homogenous semi-solid preparations consisting of opaque Emulsion systems they're consistency in
real logical properties depend on the type of emulsion either water in oil or oil in water and on the
nature of the solids in the internal phase creams are intended for application to the skin or certain
mucus membranes for protective therapeutic or prophylactic purposes especially where an
inclusive effect is not necessary the term cream is most frequently used to describe some
cosmetically acceptable types of preparations.

2 Gels and jellies are usually homogenous clear semi-solid preparations consisting of a liquid phase
within a three-dimensional polymeric Matrix with physical or sometimes chemical cross linkage by
means of suitable Jellie agents

Gels are applied to the skin or certain mucus membranes for protective therapeutic or prophylactic
purposes.

Gels colloidal suspensions of the hydrated forms of insoluble drugs.

Jellies are transparent or translucent non-greasy salmon solid preparations containing more water
than gels.

3 ointment ointments are homogeneous semi-solid preparations intended for external application
to the Skinner mucus membranes they're used as emollients are for the application of active
ingredients to the skin for protective therapeutic or prophylactic purposes and where a degree of
inclusion is desired.
4 what masses of solid substances apply to the skin for their fomentation action in order to provide
relief from pain or reduce inflammation or to act as a counter irritant

nowadays pulses are considered as outdated preparation heavy Talent is commonly included in the
formula for preparing a poultice because it act as a carrier of heat the purpose is applied to the
affected part after heating it in a China dish with occasional stirring until the heat is tolerated on
the back of the hand the melted is spread as thick film on the dressing material and applied as hot
as the patient can bear into the affected area such as kale and poultice.

5 plasters dosage semi-solid masses made by incorporating medicaments in residence or waxy

bases which are melted and spread on suitable backing material they're mainly used to afford
protection in mechanical support to bring medication into close contact with the surface of the
skin to provide an inclusive and macerating action.

6 suppositories suppositories or unit dosage form of medicament for insertion into body cavities
other than the mount they may be inserted into rectum vagina ear nasal cavity braided into the
suppository base in the product is formulated in such a way that they will either melt or dissolve in
body cavity fluid to release the drug they are available in different shapes sizes and weights they
are used for local and systemic action.