d _ Carbene CEt) Cc

PPS1 C 3 V 6
X E

E c C2step)
alran
C-C=C H C-c=C-C

Bhydroxy keone Fas*

Ez TS (1 step)
Ani-Eliminaion
Reackivi Stab. ot Alkene

3 Major Hoffmanh
(°>2°>)
Ac.Ko Dehydoehale
CC

R-C +2zm t GR LodhloJ

R-CC-R
 BLG N
ECB BL (Cs
NR3 Sanalest A
C-e

Cstablity)lky)
Hotfman

Syn-Ei.
C C
-

R--0-c-
CH CC

Heffmann fo
Sum C-F
BLG
EilE
KNSR

Pouge of LG a
Bast ciy

SLze2EN

&oR-2-0a

Ac dic Sr
R-CoD4A HCL
H Weat LG
R-CH I Ra CH-I R-C-I
2 3

SN LS+ SN'] [SN'3

S N O* CH,XRO, CN, SH, NO-

w N O> HOHNHa ,R-ÖH
SN'

SN C C step) Reenic tAi»

PeS
Rate LG
Stable

A NA AA
HoH HOcR

SA
Retunkien nversien
RM

S rS (tsto wWalden Ihversie

CBack-side atack

Rate &-I
SH

CH-X Ho-CH
.v
S N R" in Atkyl a ides

OHOHA S ROH
ROR'

OR'oH
Wiidscn R'oNat SN ROR
E her Sgn

Finkelstein Nal S R7
+
Halegeh Ro Acetone Na
Exchang
Ren SN R-F
Swarts
A"
ApF Ag
A KcN SN R-CEN+KX
B . Aa Ci S N' - R-NE C + A

SN
IA. KN SN R-0-N=0 + RX

R-X
eLB. Aa SN
R-NtAg
SN R-OH +Kx
A . kOH

SN
-Aq. kSH SN R-SH+R*
SN R-o--R

SN R-cEC-R
-R-ce c
A. LiA H

R - H
L 8. Na 3 Hu

A meist Agao R-OH

-
R-0RR
8 . dry ga0

A. NH A N H
L
Hfmann 3 R- N-R x*
Ameneyis

uarternary
Anmnium
Salt
 Comple+e Recemi M
HydniSVS
CoOM + MH3
C E N -
Partal
d t el y S i s

C - NH
s + e p h e s

SnC,26 CHO + N

LaT
MndiS

CH - NH
ts-OH
 SN

LucaSs Test CSN)

w

bho t', a° & 3 Alcehol

Diitinguish
An h Zn
Zn
Rea gent cenc H t
absor os HO)
Fer &
Alcohel Turbidiy
3Alc F e sec

2Al 5 min.

1 Al a hr
Darzens Method Csocl2 Thi cny Chlevi
SNR

SOCl 2
Py i d n e
R-C Cinversicr)
R-OH
Sod Petenhovn)
SN
4Hunsdicker Reacion
Silver Salt
Breno CemP

R-C-o Aq cel -Br+ Ag Ba

Ppt
 oecreacing pOrder
Leavin P o er f Some

- NEN
cF3CFa-o N O)
Best LG
Triflat e coT) Nosylate -oS roSyate (-o B )

c S-0
CH3 S~0
O
Tosy late C-OTS) AeNlate teMS) Meslate C-o Ms)

F CH G6

C-oAC)

C
CHs-o 7 ou R-o

Bad LG
Etet of Nu
Qualitative Propert
Stronq Nu C -ve ion)

SH
eak Nu NeutralD
Nudesphile

SN'

Quanitaive Propexhy

SNR SN
R+e ef SNN' [R -I
Rate e SN [A xJ Cu

Raeo
Ratec SN'
SN

Conc o Nu

o aq. KoH
.CH CH-CH-Br
. M

aq. KOH SN
CHa-CH -B
2
.0 M

cone. u

.CC's), C- Br HO SN
O.1 M

CCH)3 C-Br Ho
o.0MA

Re 2
Cind * Cone. of Hu )