SAN PABLO COLLAGE

COLLAGE OF NURSING

DRUG STUDY

Patient Name: ____

Generic – Brand name Classification/ Indication Side effects/ Nursing Consideration Patient teaching
Adverse Reaction
(Common/Life-threatening)
Generic name: Oral phylloquinone is Cardiac Hypersensitivity. If your symptoms or
indicated to treat disorders: Dyspnoea. health problems do not
Phytomenadione prothrombin deficiency Gastrointestinal Special Precautions get better or if they
caused by coumarin or disorders: Taste Patient with mechanical become worse, call your
Brand name: indanedione derivatives; disturbance. heart valves. Hepatic doctor. Do not share your
and Injury, poisoning and impairment. Elderly. drugs with others and do
Mephytom hypoprothrombinemia procedural Children. Pregnancy and not take anyone else’s
secondary to antibacterial lactation.
complications: Irritation, drugs. Some drugs may
therapy, salicylates, or
phlebitis, schleroderma- have another patient
obstructive jaundice or
biliary fistulas with like lesions; information leaflet. If you
concomitant bile salt erythematous, indurated, have any questions about
administration. and pruritic plaques this drug, please talk with
(repeated inj). your doctor, nurse,
Parenteral (intravenous, Investigations: Rapid or pharmacist, or other
intramuscular, and weak pulse. health care provider.
subcutaneous) Nervous system Some drugs may have
phylloquinone is indicated disorders: Dizziness. another patient
to treat coagulation Skin and subcutaneous information leaflet.
disorders due to faulty tissue disorders: Sweating. Check with your
formation of coagulation Vascular pharmacist. If you have
factors II, VII, IX, and X disorders: Hypotension, any questions about this
caused by vitamin K cyanosis, flushing. drug, please talk with
deficiency or some
Potentially Fatal: Rarely, your doctor, nurse,
interference with vitamin
K activity. These
indications include the
above indications as well
as hypoprothrombinemia
secondary to sprue,
ulcerative colitis, celiac
disease, intestinal
resection, pancreatic
cystic fibrosis, or regional
enteritis; or
hypoprothrombinemia
caused by interference
with vitamin k
metabolism
anaphylactoid reactions pharmacist, or other
(IM/IV). health care provider. If
you think there has been
an overdose, call your
poison control center or
get medical care right
away. Be ready to tell or
show what was taken,
how much, and when it
happened

Generic – Brand name Classification/ Indication
Generic name: Tramadol/Paracetamol •
tablets are indicated for
Paracetamol the symptomatic • bloody or cloudy urine.
treatment of moderate to•
Brand name: severe pain. The use of
Tramadol/Paracetamol
Amadol , tramadol should be restricted to
patients whose moderate
to severe pain is • pain in the lower back
considered to require a
combination of tramadol
and paracetamol (see also •
section 5.1.).
• skin rash, hives, or itching.
SAN PABLO COLLAGE
COLLAGE OF NURSING
DRUG STUDY
Side effects/
Adverse Reaction
(Common/Life-threatening)
Bloody or black, tarry
stools.
fever with or without
chills (not present before
treatment and not caused
by the condition being
treated)
and/or side (severe
and/or sharp)
pinpoint red spots on the
skin.
Nursing Consideration Patient teaching
Hypersensitivity to *Instruct patients to
tramadol or paracetamol. never take more than
Significant respiratory 4,000 mg of
depression, acute or acetaminophen per 24
severe bronchial asthma hours. This includes all
(in unmonitored setting or forms of acetaminophen
lack of resuscitative and acetaminophen-
containing products.
equipment), known or
*Do not take
suspected gastrointestinal
acetaminophen with
obstruction, including alcohol due to the risk of
paralytic ileus; liver toxicity.
uncontrolled epilepsy. *Educate that
Acute intoxication with acetaminophen can
centrally-acting increase anticoagulant
analgesics, opioids, effects. If the patient is
hypnotics, psychotropic taking warfarin,
drugs, or alcohol. CYP2D6 *acetaminophen can
ultrarapid and poor increase the risk of
metabolisers. Severe bleeding. Teach the
hepatic impairment. patient to monitor for
Children <12 years; post- bruising and signs of
operative use in children bleeding, and to prevent
the risk of injury.
<18 years who have
*Acetaminophen may not
undergone tonsillectomy
be safe for children under
and/or adenoidectomy; the age of 2. Always
adolescents between 12-
18 years who have other
risk factors (e.g. obesity,
obstructive sleep apnoea)
that may increase their
sensitivity to respiratory
depression. Concomitant
use or within 2 weeks
after MAOI therapy.
discuss with a healthcare
provider first.
Acetaminophen comes in
preparations and dosages
for children such as
Children’s Tylenol liquid.
Always use the
appropriate dropper or
measuring cup provided
when administering to
children.
*Keep out of reach of
children to prevent
poisoning.
*Store at room
temperature.
Suppositories should be
stored in the refrigerator.
*Acetaminophen may be
taken with or without
food.

Generic – Brand name Classification/ Indication
Generic name: Dexamethasone
and ciprofloxacin otic
Dexamethasone Sodium suspension is indicated for
Phosphate bacterial infections with
inflammation in acute
Brand name: otitis media and acute
otitis
Mohsidex externa. Intramuscular
and intravenous injections
are indicated for a
number of endocrine,
rheumatic, collagen,
dermatologic, allergic,
ophthalmic,
gastrointestinal,
respiratory, hematologic,
neoplastic, edematous,
and other conditions. Oral
tablets are indicated for
the treatment of multiple
myeloma. An intravitreal
implant is indicated for
some forms of macular
edema and non-infectious
posterior uveitis affecting
SAN PABLO COLLAGE
COLLAGE OF NURSING
DRUG STUDY
Side effects/
Adverse Reaction
(Common/Life-threatening)
Significant:
Adrenal suppression (e.g.
hypercortisolism,
suppression of
hypothalamic-pituitary-
adrenal [HPA] axis);
Kaposi sarcoma;
myopathy; perineal
irritation, psychiatric
disturbance,
immunosuppression (e.g.
secondary infections,
activation of latent
infections, mask acute
infection); increased intra-
ocular pressure, open-
angle glaucoma and
cataracts. Rarely,
anaphylactoid reactions
Endocrine
disorders: Growth
retardation in children.
Nursing Consideration
Systemic fungal
infections; systemic
infection unless being
treated with specific anti-
infectives. Perforation of
drum membrane (otic).
Administration of live
virus vaccine.
Special Precautions
Patient with
hypertension, acute
MI, heart failure,
diabetes mellitus,
gastrointestinal diseases
(e.g. diverticulitis
intestinal anastomoses,
active or latent peptic
ulcer ulcerative colitis);
ocular diseases (e.g.
cataracts, glaucoma,
history of ocular herpes
simplex); osteoporosis,
history of seizure
disorder, thyroid disease.
Renal and hepatic
impairment. Elderly.
Patient teaching
If your symptoms or
health problems do not
get better or if they
become worse, call your
doctor. Do not share your
drugs with others and do
not take anyone else’s
drugs. Some drugs may
have another patient
information leaflet. If you
have any questions about
this drug, please talk with
your doctor, nurse,
pharmacist, or other
health care provider.
Some drugs may have
another patient
information leaflet. Check
with your pharmacist. If
you have any questions
about this drug, please
talk with your doctor,
nurse, pharmacist, or
other health care
provider. If you think
the posterior of the eye. Eye disorders: Bacterial Children. Pregnancy and there has been an
Various ophthalmic keratitis, eye irritation lactation. Avoid abrupt overdose, call your poison
formulations are indicated and pruritus, burning withdrawal or rapid dose control center or get
for inflammatory sensation, ocular reduction. medical care right away.
conditions of the eye. discomfort. Be ready to tell or show
General disorders and what was taken, how
admin site much, and when it
conditions: Impaired happened.
wound healing.
Investigations: Weight
gain.
Metabolism and nutrition
disorders: Cushing’s
syndrome, obesity.
Musculoskeletal and
connective tissue
disorders: Osteoporosis.
Nervous system
disorders: Headache,
muscle atrophy.
Psychiatric
disorders: Euphoria,
depression, suicidal
tendencies.
Skin and subcutaneous
tissue disorders: Skin
fragility.

Generic – Brand name Classification/ Indication
Generic name: Pitocin is indicated for
induction of labor in
Oxytocin patients with a medical
indication for the
Brand name: initiation of labor, such as
Rh problems, maternal
Gyne- tocin diabetes, preeclampsia at
or near term, stimulation
or reinforcement of labor,
as in selected cases of
uterine inertia; as
adjunctive therapy in the
management of
incomplete or inevitable
abortion. In the first
trimester, curettage is
generally considered
primary therapy.
SAN PABLO COLLAGE
COLLAGE OF NURSING
DRUG STUDY
Side effects/
Adverse Reaction
(Common/Life-threatening)
MATERNAL
CNS:
subarachnoidhemorrhage,
seizures, coma.
CV: arrhythmias, HTN,
PVCs,hypotension,
tachycardia.
Gl: nausea, vomiting.
GU: abruptio
placentae,tetanic uterine
contractions,postpartum
hemorrhage,uterine
rupture, impaireduterine
blood flow,
pelvichematoma,
increased uterine motility.
Hematologic:
afibrinogenemia, possibly
related to postpartum
bleeding, pelvic
hematoma.
Other: anaphylaxis, death
Nursing Consideration
Contraindicated in
patient’s hypertensive to
drug, fetal distress,
hydramnios,
partialplacenta previa,
prematurity, border line
cephalopelvic
disproportion, and any
condition in which there is
a predisposition for
uterine rupture, such as
previous major surgery on
the cervix or uterus
including cesarean
section, overdistention of
the uterus, grand
multiparity, or past
history of uterine sepsis
or of traumatic delivery.
Because of the variability
of the combinations of
factors which may be
present in the conditions
listed above, the
definition of
Patient teaching
Dx:
a. Monitor fetal heart rate
and uterine contractions
before augmenting and
inducing labor.
b. Monitor fluid intake
and output. Anti-diuretic
effect may lead to fluid
overload seizures and
coma from water
intoxication.
Edx:
a. Inform the patient that
Administering the drug
during labor avoids
excessive stimulation to
the uterus or harm to the
fetus.
b. Educate the patient to
tell the physician about all
her medical conditions or
allergies and all the
medicines the patient is
using
from oxytocin-induced
water intoxication,
hypersensitivity reactions.
FETAL
CNS: infant brain
damage,seizures.CV:
bradycardia, arrthymias
PVCS.
EENT: neonatal retinal
hemorrhage.
HEPATIC: neonatal
jaundice
‘’unusualcircumstances” c. Report seizures or
must be left to the coma-like responses to
judgment of the the physician or nursing
physician. staff immediately.
d. Caution: any signs of
fetal distress or asphyxia,
such as decreased fetal
heartrate, arrhythmias,
meconium discharge
or decreased or absent
fetal movements. Report
these signs to the
physician or nursing staff
immediately.

Generic – Brand name Classification/ Indication Side effects/
Adverse Reaction
(Common/Life-threatening)
Generic name: The mechanism of action
of Buscopan is that it
blocks the muscarinic
Hyoscine N-
Butylbromide receptors found on the
smooth muscle walls
Brand name: which means its blocks the
action of acetylcholine on
the receptors found within
Buscopan
the smooth muscle of the
gastrointestinal and
urinary tract and thus
reduces the spasms and
contractions. This relaxes
the muscle and thus
reduced the pain from the
cramps and spasms.
Indication
1. Spasm in the
genitourinary
tract
SAN PABLO COLLAGE
COLLAGE OF NURSING
DRUG STUDY
Nursing Consideration Patient teaching
▪ CNS: dizziness, anaphylactic Buscopan Tablets 1. Take this drug
reactions, anaphylactic should not be
shock, increased ICP, 30 minutes to
administered to
disorientation, restlessness, patients with 1 hour before
irritability, dizziness, myasthenia gravis, meals
drowsiness, headache, megacolon and narrow
confusion, hallucination, 2. Buscopan will
angle glaucoma. In
delirium, impaired memory potentiate
addition, they should
▪ CV: hypotension,
not be given to the effect of
tachycardia, palpitations,
flushing patients with a known alcohol and
▪ GI: Dry mouth, hypersensitivity to other CNS
constipation, nausea, hyoscine-N-
butylbromide or any depressants.
epigastric distress
▪ DERM: flushing, dyshidrosis other component of 3. Do not take
▪ GU: Urinary retention, the product. antacids and
urinary hesitancy
antidiarrheal
▪ Resp: dyspnea, bronchial
plugging, depressed 2 to 3 hours
respiration prior to raking
▪ EENT: mydriasis, dilated
this drug.
pupils, blurred vision,
photopobia, increased 4. It is not
intraocular necessary to
pressure, difficulty of
take the
swallowing.
medication if
2. Spasm in the you are not in
gastrointestinal pain.
tract 5. Avoid driving
3. Spasm in the or operating
biliary tract machinery
4. Colic after
parenteral
dose.
 SAN PABLO COLLAGE
COLLAGE OF NURSING

DRUG STUDY

Generic – Brand name Classification/ Indication Side effects/ Nursing Consideration Patient teaching
Adverse Reaction
(Common/Life-
threatening)
Generic name: CV: tachycardia, angina, Contraindicated in: Emphasize the
Hydralazine is indicated arrhythmias, edema, •Hypersensitivity; importance of continuing
Hydralazine alone or adjunct to orthostatic hypotension •Some products contain to take this medication,
Hydrochloride standard therapy to treat Derm: rash tartrazine and should be even if feeling well.
essential hypertension. A GI: diarrhea, nausea, avoided in patients with Instruct patient to take
Brand name: combination product with vomiting known intolerance. Use medication at the same
isosorbide dinitrate is MS: arthralgias, arthritis Cautiously in: time each day; last dose
Neuro: dizziness, Cardiovascular or of the day should be
Aprezobas indicated as an adjunct
drowsiness, headache, cerebrovascular disease; taken at bedtime. Take
therapy in the treatment
peripheral neuropathy •Severe renal impairment missed doses as soon as
of heart failure. (dose modification may remembered; do not
be necessary) double doses. If more
•Severe hepatic than 2 doses in a row are
impairment (dose missed, consult health
modification may be care professional. Must be
necessary); discontinued gradually to
avoid sudden increase in
BP. Hydralazine controls
but does not cure
hypertension.
Encourage patient to
comply with additional
interventions for
hypertension (weight
reduction, low-sodium
diet, smoking cessation,
moderation of alcohol
intake, regular exercise,
and stress management).
Instruct patient and family
on proper technique for
BP monitoring. Advise
them to check BP at least
weekly and report
significant changes.
Patients should weigh
themselves twice weekly
and assess feet and ankles
for fluid retention. May
occasionally cause
drowsiness. Advise
patient to avoid driving or
other activities requiring
alertness until response to
medication is known.
Caution patient to avoid
sudden changes in
position to minimize
orthostatic hypotension.
Advise patient to notify
health care professional
of all Rx or OTC
medications, vitamins, or
herbal products being
taken and to consult with
health care professional
before taking other
medications, especially
cough, cold, or allergy
remedies. Instruct patient
to notify health care
professional of
medication prior to
treatment or surgery.
Advise patient to notify
health care professional
immediately if general
tiredness; fever; muscle
or joint aching; chest pain;
skin rash; sore throat; or
numbness, tingling, pain,
or weakness of hands and
feet occurs. Vitamin B6
(pyridoxine) may be used
to treat peripheral
neuritis.
Rep: Advise females of
reproductive potential to
notify health care
professional if pregnancy
is planned or suspected or
if breastfeeding.
Emphasize the
importance of follow-up
exams to evaluate
effectiveness of
medication.
 SAN PABLO COLLAGE
COLLAGE OF NURSING

DRUG STUDY

Generic – Brand name Classification/ IndicationSide effects/ Nursing Consideration Patient teaching
Adverse Reaction
(Common/Life-
threatening)
Generic name: -anemia Contraindications and ▪ Take this drug
Penicillins had been very -inflammatory in the cautions around-the-clock.
Ampicillin (as sodium)
effective against S. kidney ▪ Take the full course
aureus; in the past, of therapy; do not
-swelling in large and ▪ Contraindicated with
however, Staphylococcus stop taking the drug
Brand name: small intestine allergies to
aureus has become penicillins, if you feel better.
-seizure
capable of exhibiting cephalosporins, or ▪ Take the oral drug
Liferzin -inflammatory of the
resistance against them other allergens. on an empty
by producing a penicillin mouth ▪ Use cautiously with stomach, 1 hour
hydrolyzing enzyme – renal disorders. before or 2 hours
penicillinase. After that, Nursing considerations after meals; do not
ampicillin was take with fruit juice
developed to overcome Assessment or soft drinks; the
this issue and extend the ▪ History: Allergies to oral solution is stable
antimicrobial coverage penicillins, for 7 days at room
of penicillins. It is also cephalosporins, or temperature or 14
resistant to acid so it can other allergens; days refrigerated.
be administered renal disorders; ▪ This antibiotic is
orally.[1] lactation specific to your
▪ Physical: Culture problem and should
Ampicillin has effective infected area; skin not be used to self-
minimum inhibitory color, lesion; R, treat other
concentration for most of adventitious sounds; infections.
medically important bowel sounds; CBC, ▪ You may experience
organisms in infectious LFTs, renal function these side effects:
disease like Escherichia tests, serum Nausea, vomiting, GI
coli: MIC = 4 electrolytes, Hct, upset (eat frequent
mg/L, Staphylococcus urinalysis small meals),
aureus: MIC = 0.6-1 diarrhea.
mg/L, Streptococcus ▪ Report pain or
pneumoniae: MIC = discomfort at sites,
0.03-0.06 unusual bleeding or
mg/L, Hemophilus bruising, mouth
influenzae: MIC = 0.25 sores, rash, hives,
mg/L.[1] To reduce the fever, itching, severe
development of drug- diarrhea, difficulty
resistant bacteria and breathing.
maintain
the effectiveness of
ampicillin should be
used only to treat
infections that are
proven or strongly
suspected to be caused
by bacteria.
 SAN PABLO COLLAGE
COLLAGE OF NURSING
DRUG STUDY
Generic – Brand name Classification/ Indication Side effects/
Adverse Reaction
(Common/Life-threatening)
Generic name: The amikacin sulfate Hypersensitivity,
injection is indicated in neurotoxicity, ototoxicity,
Amikacin Sulfate the short-term nephrotoxicity,
treatment of serious neuromuscular blockade,
Brand name: bacterial infections due respiratory paralysis, fungal
to susceptible strains of or bacterial
Cinmik, Arikayce gram-negative bacteria, superinfection, Clostridium
including Pseudomonas difficile associated diarrhoea
species, Escherichia coli, (CDAD), pseudomembranous
species of indole- colitis (prolonged use).
positive and indole- Inhalation: Bronchospasm,
negative Proteus, haemoptysis, hypersensitivity
Providencia species, pneumonitis and alveolitis;
Klebsiella-Enterobacter- COPD, infective exacerbation
Serratia species, as well of COPD or bronchiectasis.
as Acinetobacter (Mima- Blood and lymphatic system
Herellea) species. disorders: Anaemia,
eosinophilia.
Ear and labyrinth
disorders: Tinnitus,
hypoacusis, vertigo.
Gastrointestinal
disorders: Nausea, vomiting;
diarrhoea, dry mouth,
laryngitis, oral candidiasis,
Nursing Consideration Patient teaching
Contraindications Tell your doctor if you
Hypersensitivity to have or have ever had
amikacin and other burning, tingling, or
aminoglycoside antibiotics. numbness in the hands,
Myasthenia gravis. arms, feet, or legs;
Concomitant or sequential muscle twitching or
administration of oral or weakness; or seizures.
topical drugs that are
The risk that you will
neurotoxic, ototoxic or
develop serious kidney,
nephrotoxic; concomitant
hearing, or other
use with potent diuretics.
problems is greater if
Special Precautions
you are taking certain
Patient with pre-existing
vertigo, tinnitus, or medications.
hearing loss, vestibular
damage; neuromuscular
disorders (e.g. Parkinson's
disease), hypocalcaemia.
Dehydrated patients. Used
as a 2nd-line treatment for
staphylococcus infections.
Patients
with m.1555A>G mutation.
Renal impairment.
Premature infants,
neonates, children and
dysgeusia (inhalation). elderly. Pregnancy and
General disorders and lactation.
administration site
conditions: Pyrexia, injection
site pain (IM); fatigue
(inhalation).
Investigations: Decreased
weight (inhalation).
Metabolism and nutrition
disorders: Hypomagnesaemia.
Musculoskeletal and
connective tissue
disorders: Arthralgia, muscle
twitching; musculoskeletal
pain (inhalation).
Nervous system
disorders: Balance disorder,
headache, paraesthesia,
tremor.
Renal and urinary
disorders: Oliguria,
albuminuria, azotaemia, RBC
urine, WBC urine.
Respiratory, thoracic and
mediastinal disorders: Cough,
dyspnoea, dysphonia,
wheezing, increased sputum,
vocal cord inflammation,
throat irritation,
oropharyngeal pain
(inhalation).
Skin and subcutaneous tissue
disorders: Rash, pruritus,
urticaria.
Vascular
disorders: Hypotension.