Dr.

Moaaz Wahdan 2023/24 Biochemistry

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 Dr.Moaaz Wahdan 2023/24 Biochemistry
Amino Acids and Proteins Structure & Function
Seminar 2023
1. Which is the correct protein level that includes liner peptide bonding between
amino acids?
a. Primary structure.
b. Secondary structure.
c. Tertiary structure.
d. Quaternary structure.
2. At which protein level of protein structure, we can find an interaction between
different numbers of polypeptide chains?
a. Primary structure.
b. Secondary structure.
c. Tertiary structure.
d. Quaternary structure.
3. Tripeptide means which of the following?
a. Two amino acids connected by two bonds
b. Three amino acids and three bonds
c. Three amino acids and two bonds
d. Two amino acids and three bonds
4. True or false questions: Please raise letter (A) if the answer is (true) and letter (B)
if the answer is (false)
1) Non-Essential amino acids cannot be synthesized in the body.
2) Tripeptides are linear polymers that range from 4 to 8000 amino acid
residues.
3) The carbon skeleton of amino acids can be used for glucose production.
4) Peptides and proteins are polymers that are formed from twenty amino
acids connected to each other by hydrogen bonds.

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 Dr.Moaaz Wahdan 2023/24 Biochemistry
5. Which of the following is responsible for specifying the 3D shape of a protein?
a. The peptide bonds
b. The amino acids sequence
c. Interaction with other polypeptides
d. Interaction with molecular chaperons

6. Amino acids with aromatic side chain are.

a. tryptophan, asparagine, tyrosine

b. tryptophan, threonine, tyrosine
c. phenylalanine, tryptophan, serine
d. phenylalanine, tryptophan, tyrosine

7. Which of the following amino acids must be supplemented in the diet?

a. phenylalanine
b. cysteine
c. glutamine
d. asparagine

8. Which of the following is an amino acid?

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Answers

4)
1- F
1) a 2- F 7) a
3- T
4- F
2) d 5) b 8) d
3) c 6) d

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 Dr.Moaaz Wahdan 2023/24 Biochemistry
Quiz
1. Valine, leucine and isoleucine are:
a. Non essential amino acids
b. Essential amino acids.
c. Sulfur containing amino acids.
d. Basic amino acids.
2. Essential amino acid with OH group is:
a. Valine
b. tryptophan
c. Threonine
d. phenylalanine
3. An Imino group is present in:
a. Alanine.
b. Proline.
c. Serine
d. Aspartic acid
4. Regarding amino acid lysine all the following is correct Except:
a. Contain two amino, one carboxy groups
b. Essential amino acid
c. Glucogenic amino acid
d. A constituent of collagen
5. Which of the following is semi essential amino acid ?
a. Histidine
b. Lysine
c. Alanine
d. Aspartic acid.
6. Which of following amino acids has a positively charged
side chain:
a. arginine
b. aspartate
c. glutamate
d. asparagine

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 Dr.Moaaz Wahdan 2023/24 Biochemistry
7. A Sulphur containing dipeptide is :
a. Cystine
b. Glutathione
c. Lysine
d. Arginine

8. Quaternary structure is present in :

a. Coagulated proteins
b. Denaturated protein
c. Hemoglobin
d. None of the above

9. What is/ are the bond/s responsible for the primary structure of protein ?
a. Peptide bond
b. Hydrogen bond
c. Van der Waals
d. All of the above

10. All of the following are considered "weak" interactions in proteins,

except:
a. Hydrogen bonds.
b. Hydrophobic interactions.
c. Ionic bonds.
d. Peptide bonds.

11. Roughly how many amino acids are there in one turn of an a helix?
a. 4
b. 6
c. 2
d. 10

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12. ..........Bond formed between positive and negative side chain of basic
and acidic amino acids
a. ionic
b. hydrogen
c. disulfide
d. non of the above

Answers

1) b 5) a 9) a
2) c 6) a 10) d
3) b 7) a 11) a
4) c 8) c 12) a

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Dr.Moaaz Wahdan 2023/24 Biochemistry
‫أسئلة من مصادر تانية‬
1) Cystein, cystine and methionine are:
a. Essential amino acids
b. sulfur containing amino acids.
c. acidic amino acids.
d. All of the above.
2) Two amino groups are present in:
a. Glutamate
b. Leucine
c. Lysine
d. Threonine
3) Amino acids are
a. building blocks of carbohydrates
b. building blocks of nucleic acids
c. building blocks of lipids
d. building blocks of proteins
4) Amino acids have
a. both amino group and carboxyl group
b. both amino group and keto group
c. amino group only
d. carboxyl group only
5) The simplest amino acid is
a) Proline
b) methionine
c) glycine
d) serine
6) Which of the following is an Imino acid
a. serine
b. threonine
c. valine
d. proline

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Dr.Moaaz Wahdan 2023/24 Biochemistry
7) The naturally occurring form of amino acid in proteins
a. L-amino acids only
b. D-amino acids only
C. both L and D amino acids
d. none of these
8) Sulphur containing amino acids are
a. Cysteine and methionine
b. Methionine and threonine
c. Cysteine and threonine
d. Cysteine and serine
9) Aromatic amino acids include
a. Phenylalanine, tyrosine and tryptophan
b. Phenylalanine, serine and tryptophan
c. Threonine, tyrosine and tryptophan
d. Asparagine, tyrosine and tryptophan
10) Positively charged basic amino acids are
a. Lysine and arginine
b. Lysine and asparagine
c. Glutamine and arginine
d. Lysine and glutamine
11) Acidic amino acids include
a. Arginine and glutamate
b. Aspartate and asparagine
c. Aspartate and lysine
d. Aspartate and glutamate

12) Amino acids with hydroxyl groups are

a. serine and alanine
b. Alanine and valine
c. serine and threonine
d. Valine and isoleucine

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Dr.Moaaz Wahdan 2023/24 Biochemistry
13) Which of the following is an aromatic amino acid?
a. Phenylalanine
b. Serine
c. Arginine
d. Glutamic
14) Under physiological conditions, what is the charge of
the amino group of the side-chain of arginine?
a. Positive
b. Negative
c. Not charged
d. Positively or negatively charged.
15) Which of the following is an amino acid allows
flexibility in polypeptide chains?
a. Lysine
b. Glycine
c. Glutamine
d. Proline

16) Which of the following is an essential amino acid?

a. Glycine
b. Phenylalanine
c. Cysteine
d. Serine

17) Which of the following is an amino acid gives both glucose

and ketone bodies?
a. Serine
b. Glycine
c. Tyrosine
d. Proline

18) Which among the following is the property of amino acids?

a. 50 amino acids are commonly found in mammalian proteins.
b. Most amino acids occurring naturally in proteins are of the B
type
c. All the amino acids in human proteins are the L stereoisomer

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Dr.Moaaz Wahdan 2023/24 Biochemistry
d. When the amino group is attached to the third carbon, the
amino acid is called a-amino acid.

19) Which among the following is the true state about non-essential
amino acids?
a. Are not components of tissue proteins
b. May be synthesized in the body from essential amino acids
c. Have no role in the metabolism
d. May be synthesized in the body in diseased states

20) Which among the following is an amino acid is known as a

"structural' amino acid as it puts a kink in polypeptide chains?
a. Glycine
b. Proline
c. Lysine
d. Alanine

21) Which one of the following is an amidic amino acid?

a. Glutamic
b. Lysine
c. Glutamine
d. Aspartic

22) ……………… is aliphatic basic amino acid:

a. arginine
b. aspartic acid
c. histidine

23) Two amino group are present in …………

a. glutamic
b. leucine
c. lysine

24) Which of the following is non protein amino acid:

a. arginine
b. ornithine
c. proline

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25) The naturally occurring form of amino acids is:
a. L-amino acid
b. D-amino acids
c. both of them

26) Positively charged amino acids are:

a. lysine, arginine
b. lysine, asparagine
c. glutamine, arginine

27) Imidazole ring is present in

a. tryptophan
b. histidine
c. arginine

28) Guanidine ring is present in:

a. tryptophan
b. histidine
c. arginine

29) The first amino acid in protein synthesis is:

a. histidine
b. methionine
c. alanine

30) The kink in protein structure is formed by……...

a. histidine
b. proline
c. alanine

31) ………… is heterocyclic amino acid

a. histidine
b. aspartic acid
c. alanine

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Dr.Moaaz Wahdan 2023/24 Biochemistry
32) The only purely ketogenic amino acid is:
a. histidine
b. leucine
c. lysine

33) Indol group is specific for:

a. tryptophan
b. serine
c. phenylalanine

34) Which of the following is the property of the B- Sheets?

a. The -sheets usually associated with globular proteins
b. Stabilized by disulphide bonds between peptide bonds of
adjacent polypeptide chains
c. The B sheet is more common than alpha helix.
d. Polypeptide chain is in a fully extended conformation

35) Which of the following is the property of the peptide bond?

a. Peptide bond is one of bonds that stabilize the secondary
structure formation.
b. Peptide bonds are essentially planar, with no rotation about
the C-Naxis.
c. Peptide bonds in proteins are unusual.
d. Peptide bond structure is extraordinarily complex.

36) Which of the following is the structure that has hydrogen bonds
between polypeptide chains arranged side by side is?
a. Primary structure
b. α-helix
c. B-pleated sheets
d. Tertiary structure

37) Which of the following is an amino acid that does not take part
in α-helix formation?
a. Histidine
b. Tyrosine
c. Proline d. Tryptophan

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Dr.Moaaz Wahdan 2023/24 Biochemistry
38) Which of the following that ionic interactions can be formed
between their side chains?
a. Alanine and leucine
b. Leucine and valine
c. Aspartate and glutamate
d. Lysine and aspartate

39) Which of the following is bond that is formed between two

cysteine residues?
a. Disulphide
b. Peptide
c. Electrostatic
d. Hydrophobic

40) Which among the following is true about the α-helix of

proteins?
a. A pleated structure
b. Made by periodic disulphide bonds
c. Polypeptide chain is in a fully extended conformation
d. Stabilized by hydrogen bonds between NH and CO groups of
the main chain

41) Which of the following is an example of the a-helix and β.

pleated sheet in proteins?
a. Primary structure
b. Secondary structure
c. Tertiary structure
d. Quaternary structure

42) Which of the following is false about fibrous protein?

a. It is in rod like shape
b. The B-sheets usually associated with fibrous proteins
c. Hemoglobin is the best example
d. B-sheets of fibrous proteins can run parallel or anti-parallel

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43) What does the interactions between multiple polypeptide
chains form?
a. Primary structure
b. Secondary structure
c. Tertiary structure
d. Quaternary structure

44) Which of the following is primarily found in the extra cellular

matrix:
a. Collagen
b. Fibrin
c. Keratin
d. Proteoglycan.

45) ……………. Is genetically determined

a. 1ry structure
b. 2ry structure
c. 3ry structure

46) All of the following bonds stabilize tertiary structure except:

a. hydrogen bonds
b. di-sulfide bond
c. phosphodiester bond

47) …….. is present in full extended form

a. α-helix
b. β-sheets

48) Proteins of high biological value is rich in

a. essential amino acids
b. basic amino acids (arginine-lysine)
c. acidic amino acids (aspartic and glutamic acids)
d. aromatic amino acids; tyrosine, tryptophan

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Answers

1) b 14) a 27) b 40) d

2) c 15) b 28) c 41) b
3) d 16) b 29) b 42) c
4) a 17) c 30) b 43) d
5) c 18) c 31) a 44) a
6) d 19) b 32) b 45) a
7) a 20) b 33) a 46) c
8) a 21) c 34) d 47) b
9) a 22) a 35) b 48) a
10) a 23) c 36) c
11) d 24) b 37) c
12) c 25) a 38) d
13) a 26) a 39) a

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