TABLE OF CONTENTS: Volume 28 / Issue 5 / May 2022

EDITOR'S PAGE: WE’VE BEEN THINKING. . .

695 International Collaborations in Heart Failure: JCF in Latin America

Anuradha Lala, Renato D. Lopes, and Robert J. Mentz

ORIGINAL RESEARCH PAPERS

697 The Association Between Socioeconomic Status, Sex, Race / Ethnicity and In-Hospital Mortality Among
Patients Hospitalized for Heart Failure
T. Averbuch, M.O. Mohamed, S. Islam, E.M. Defilippis, K. Breathett, M.A. Alkhouli, E.D. Michos,
G.P. Martin, E. Kontopantelis, M.A. Mamas, and H.G.C. Van Spall

710 Predicting 30-Day Readmissions in Patients With Heart Failure Using Administrative Data: A Machine
Learning Approach
Vishal Sharma, Vinay Kumar Kulkarni, Finlay Mcalister, Dean Eurich, Shanil Keshwani,
Scot H. Simpson, Don Voaklander, and Salim Samanani
723 Under-Enrollment of Obese Heart Failure with Preserved Ejection Fraction Patients in Major
HFpEF Clinical Trials
Joban Vaishnav, Lisa R. Yanek, Virginia S. Hahn, Eunice Yang, Rishi Trivedi, David A. Kass,
and Kavita Sharma

EDITORIAL COMMENT

732 Inclusion Criteria for Heart Failure With Preserved Ejection Fraction Clinical Trials: Making the Case for
Precision Diagnosis and Greater Inclusivity
Ravi B. Patel, and Sanjiv J. Shah
736 Associations Between Prognostic Awareness, Acceptance of Illness, and Psychological and
Spiritual Well-being Among Patients With Heart Failure
Semra Ozdemir, Jia Jia Lee, Chetna Malhotra, Irene Teo, Khung Keong Yeo, Aung Than,
Kheng Leng David Sim, and Eric Finkelstein

744 Valsalva-derived Measures and Phenylephrine Test in Patients With Heart Failure With
Reduced Ejection Fraction Receiving Comprehensive Neurohormonal Blockade Drug
Therapy: A 5-year Event-free Survival Analysis
ska-Mader, Krzysztof Nowak,
Anna Podsiad»y, Bart»omiej Paleczny, Martyna Olesin
Tymoteusz Okupnik, Ma»gorzata Wyciszkiewicz, Wojciech ºopusiewicz, Piotr Ponikowski,
and Beata Ponikowska

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TABLE OF CONTENTS: Volume 28 / Issue 5 / May 2022
756 Evaluation of Medicare Claims for the Development of Heart Failure Diagnostics
Ramesh Wariar, Gezheng Wen, Caroline Jacobsen, Stephen Ruble, and John P. Boehmer

765 Frailty Measures of Patient-reported Activity and Fatigue May Predict 1-year Outcomes in
Ambulatory Advanced Heart Failure: A Report From the REVIVAL Registry
Anuradha Lala, Palak Shah, Shokoufeh Khalatbari, Matheos Yosef, Maria M. Mountis,
Shawn W. Robinson, David E. Lanfear, Jerry D. Estep, Neal Jeffries, Wendy C. Taddei-Peters,
Lynne W. Stevenson, Blair Richards, Douglas L. Mann, Donna M. Mancini, Garrick C. Stewart,
and Keith D. Aaronson, Guest Editor: Tariq Ahmad, MD

EDITORIAL COMMENT
775 Moving the Field Forward: Untangling the Impact of Frailty on Patients With Advanced Heart Failure
and on Prognosticating Outcomes
Katherine A.A. Clark, and Michael G. nanna

778 The Effect of Spironolactone in Patients With Obesity at Risk for Heart Failure: Proteomic Insights
from the HOMAGE Trial
Job A.J. Verdonschot, Jo~
ao Pedro Ferreira, Anne Pizard, Pierpaolo Pellicori, Hans-Peter Brunner La Rocca,
Andrew L. Clark, Franco Cosmi, Joe Cuthbert, Nicolas Girerd, Olivia J. Waring, Michiel H.T.M. Henkens,
Beatrice Mariottoni, Johannes Petutschnigg, Patrick Rossignol, Mark R. Hazebroek, John G.F. Cleland,
Faiez Zannad, and Stephane R.B. Heymans, On behalf of HOMAGE “Heart Omics in AGEing” Consortium

EDITORIAL COMMENT
787 Paying Homage to the Power of Proteomics: Insights Into Obesity and Heart Failure From the
HOMAGE Trial
Josephine Harrington, Eleni Tseliou, Svati Shah, and Kevin S. Shah

789 Left Atrial Circulatory Assistance in Simulated Diastolic Heart Failure Model: First in Vitro and in Vivo
Chihiro Miyagi, Kiyotaka Fukamachi, Barry D. Kuban, Shengqiang Gao, Takuma Miyamoto, Christine R. Flick,
Anthony R. Polakowski, David J. Horvath, Randall C. Starling, and Jamshid H. Karimov
799 Left Ventricular Hemodynamics and Relationship With Myocardial Recovery and Optimization in
Patients Supported on CF-LVAD Therapy
Andrew N. Rosenbaum, Jeffrey B. Geske, John M. Stulak, Sudhir S. Kushwaha, Alfredo L. Clavell,
and Atta Behfar

EDITORIAL COMMENT

807 Left Ventricular Hemodynamics: Can a Direct Assessment of Left Ventricular Performance Help to Guide
Myocardial Recovery in LVAD Recipients?
Anthony J Kanelidis, and Jonathan Grinstein
TABLE OF CONTENTS: Volume 28 / Issue 5 / May 2022
GUIDELINES

810 2022 American College of Cardiology/American Heart Association/Heart Failure Society of America Guideline
for the Management of Heart Failure: Executive Summary
Paul A. Heidenreich, Biykem Bozkurt, David Aguilar, Larry A. Allen, Joni-j. Byun, Monica M. Colvin, Anita Deswal, Mark
H. Drazner, Shannon M. Dunlay, Linda R. Evers, James C. Fang, Savitri E. Fedson, Gregg C. Fonarow, Salim S. Hayek,
Adrian F. Hernandez, Prateeti Khazanie, Michelle M. Kittleson, Christopher S. Lee, Mark S. Link, Carmelo A. Milano,
Lorraine C. Nnacheta, Alexander T. Sandhu, Lynne Warner Stevenson Orly Vardeny, Amanda R. Vest, and Clyde W.
Yancy, WRITING COMMITTEE MEMBERS

e1 2022 ACC/AHA/HFSA Guideline for the Management of Heart Failure

Writing Committee Members Paul A. Heidenreich, Biykem Bozkurt, David Aguilar, Larry A. Allen, Joni J. Byun, Monica
M. Colvin, Anita Deswal, Mark H. Drazner, Shannon M. Dunlay, Linda R. Evers, James C. Fang, Savitri E. Fedson, Gregg
C. Fonarow, Salim S. Hayek, Adrian F. Hernandez, Prateeti Khazanie, Michelle M. Kittleson, Christopher S. Lee, Mark S.
Link, Carmelo A. Milano, Lorraine C. Nnacheta, Alexander T. Sandhu, Lynne Warner Stevenson, Orly Vardeny, Amanda
R. Vest, and Clyde W. Yancy, ACC/AHA Joint Committee Members, Joshua A. Beckman, Patrick T. O’Gara, Sana M. Al-
Khatib, Anastasia L. Armbruster, Kim K. Birtcher, Joaquin E. Cigarroa, Lisa de las Fuentes, Anita Deswal, Dave L. Dixon,
Lee A. Fleisher, Federico Gentile, Zachary D. Goldberger, Bulent Gorenek, Norrisa Haynes, Adrian F. Hernandez, Mark A.
Hlatky, Jos
e A. Joglar, W. Schuyler Jones, Joseph E. Marine, Daniel B. Mark, Debabrata Mukherjee, Latha P. Palaniappan,
Mariann R. Piano, Tanveer Rab, Erica S. Spatz, Jacqueline E. Tamis-Holland, Duminda N. Wijeysundera, and Y. Joseph
Woo

EDITORIAL COMMENT

831 A Clinician’s Guide to the 2022 ACC/AHA/HFSA Guideline for the Management of Heart Failure
Michelle M. Kittleson

STATE OF THE ART REVIEWS

835 Policy and Payment Challenges in the Postpandemic Treatment of Heart Failure: Value-Based Care and
Telehealth
~a, Larry A. Allen, and Nihar R. Desai
Ileana L. Pin
845 Physiology and Clinical Utility of HeartMate Pump Parameters
Mark N. Belkin, Viktoriya Kagan, Colleen Labuhn, Sean P. Pinney, and Jonathan Grinstein

PERSPECTIVES

863 All-Cause Mortality as an End Point for Heart Failure With Preserved Ejection Fraction: Underperformance or
Overambitious?
Parag Goyal, Andrew J. Sauer, and Michael W. Rich, Guest Editor: Michael Nassif, MD
TABLE OF CONTENTS: Volume 28 / Issue 5 / May 2022
BRIEF REPORTS

866 Improved Prognostic Performance of Cardiac Power Output With Right Atrial Pressure: A Subanalysis of the
ESCAPE Trial
Mark N. Belkin, Francis J. Alenghat, Stephanie A Besser, Sean P. Pinney, and Jonathan Grinstein

RESEARCH LETTER

870 Discordance of Pressure and Volume: Potential Implications for Pressure-Guided Remote Monitoring
in Heart Failure
Dmitry M. Yaranov, John L. Jefferies, Marc A. Silver, Daniel Burkhoff, Vishal N. Rao, and Marat Fudim

JCF IGNITE!

873 Cardiac Xenotransplantation: Rebirth Amidst an Uncertain Future

Mandeep R. Mehra

ECT SPOTLIGHT

875 Michele — This Is My Why, Now Let’s Find the Way. . .

Vanessa Blumer

PRESIDENT'S MESSAGE

878 Implementation of the 2022 ACC/AHA/HFSA Heart Failure Guideline: A Call to Action
Mark H. Drazner

For a full and complete Guide for Authors, please go to:

http://www.journals.elsevier.com/journal-of-cardiac-failure.