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Acut - Lymphoid Lukemia
Acut - Lymphoid Lukemia
5 points)
- Patient initials: DA
- Age: 7yrs
- Sex: Male
- Allergies: _Pt not c/o _allergy from food or medication_. Pt c/o season
allergy.
Obstetric History
Mother is 28 yrs old, and she obstetric history is gravida 4, para 4 , abortion
0.
No complain of hypertention , diabetic , or any disorder during pregnancy.
The mother did not received in each obstetric any pre natal care . just in first
and last gravida at 35 wks received pre natal care to take tetanus vaccine .
All para NSVD .
The gestational age for all children is same , and is 41wk .
1. Birth History:
Child was delivered NSVD , at 41wks , and his weight 3000 gm , no any
complications during delivery , in good general condition of baby , no
complain from any problems after delivery .
The length of 3rd stage of labor is normal, and it is about 20 minutes, and the
delivery was at hebron hospital, and she stayed for 24 hrs with the baby for
observation, then she discharged together with baby after 1day
hospitalization.
The baby apgar score at first 1-5 minutes about 8/10.
The date of birth 14/3/2002 .
PKU test was done to the baby at 4 days after delivery .
2. Nutritional History:
Breast Feeding
Child was on breast feeding for first 2wks of life, the mother was asked
about the cause of this, and she answered me the reason related to lack of
milk gradually , and this problem present with all her childrens .
After that I encourage mother for breast feeding and educate mother about it
is benefits . also encourage mother to visit gynecologist to know what is
problem.
Bottle Feeding
The mother started bottle feeding for the child from 2wk till 18 month
Others
SOLID FEEDING
The mother started to give pt solid food between 4 and 6 month , and she
concerned on special solid foods can child tolerated it , like boiled rice and
vegetables , brushed fruits, and she introduce gradually .
Chief Complaint
Pt c/o nausea and vomiting with epigastric pain , also c/o loss of
appitite and stomatitis according mother report .
Immunization: (2.5 points)
Age BCG Hep IPV OPV DPT DT dT measle MMR
B s
One day
1 months
2 months
4 months
6 months
9 months
12 months
15 months
6 years
Posture:
The posture child tall-straight well balanced.
When assess the pt muscles during rise his leg against my hand or when he
flex his , arm good flexibility and good muscles tone.
Muscles strength as well as palpation and pt can sitting and lying down
easily.
Position:
Child sleeps in many position and no special position for sleeping { in
some time sleep on RT side , or LT side , in another time pt sleep on his
back or his abdomen }.
The mother is pt was advice for the best sleeping position on side and back .
Also the mother educated the prone is risk for children because it effect on
respiration and make pressure on stomach.
The position pt during assessment on his back;
Personality
Child interact with his family members and environment , he is not
aggressive , child keep quiet before and after disease .
Pt easily interact with other childrens and try to speak with them.
Behavior
Child is cooperative with medical members in hospital, and speak with
team , and interact during procedures in almost time .
In some times behaviors pt changed such as go to crying toward some kind
of procedure , like to kept pt NPO , and pt become hypoactive .
Also same reaction during bone marrow aspiration test done, and he refused
this test befor done, but after that he agree to do it.
Pt dose not refused the medication .
Speech
In general child is quiet .
When I try to speak with pt about different subject ,pt make to discuss with
me without refused that , and he have good speech language , also he have
good reduction sound and voice.
Facial expression:
Child look quiet , and happy when he goes to games .
In another times child look irritable and sad .
No any asymmetry or involuntary movement in facial expression.
Hygiene
Child is good general hygiene , washing hands , bathing every other day ,
and maintain oral hygiene.
Also mothers child make to maintain of food hygiene , and pt to take care
for himself with his mother.
State of Nutrition
Child complain of imbalanced nutrition due to less than body requirement ,
related to loss of appitite due epigastric pain and side effect of
chemotherapy.
Chemotherapy make to the pt nausea , vomiting , epigastric pain ,
stomatitis , and this cause loss of appitite to the pt.
In general child does not refuse any kind of eat , and he likes specially rice,
meat, and juice.
The mother encourage to give pt adequate fluid intake , and suggest smaller ,
more frequent meal , low salt diet , and encourage frequent oral hygiene .
Level of Activity
Child is active well in most time ,in moderate activity level , and play with
other children , in rare time seen hypoactive and lazy , walking in square
many time during day , and go to watching TV , most time out of bed if he
didn’t c/o pain or problems .
IV.Growth Measurements:
Growth Normal Range Comments
SKIN
When I doing exam to the skin pt by palpation and inspection ,I work
to get hold of and grasp the skin ,my observation for the following :
1. skin targur : good skin targur when I grasp it , and skin return to its
normal position quickly without residual marks and good amount of
elasticity
2. color : my observation about the skin child color is pale, no cyanosis or
jaundis at the hand , lip foot was noted ,pink lip and nails in color .
Ecchymosis in some area { old canula place } due to extra vasation of blood
in to the skin because WBC in CBC IS low and the vessels easily to rupture
{ on the RT hand on elbow }.
Old small scar on the RT knee due to falling down the pt and crushing the
skin .
Redness color of skin and inflammation seen around anus area due to
pyrexia and chemotherapy
3. Temperature :
skin is warmth to touch , no cold or cyanosis
The temperature about 37c .
4. Texture
The skin is smooth and soft , no dryness or roughness.
Good skin integrity ,no odema was seen.
No dehydration or connective tissue disorder .
Good skin hygiene , no bad smell or odor.
Head a Neck
The head of the child is round in shape and symmetry ,good hygiene ,
no any scar ,odema , or protrusions .
The neck is good motility in each side, normal in size and long.
When inspect the trachea between my thumb and index, I didn’t palpate any
mass or lymph node .
The trachea is in the midline, and the thyroid gland is located at the base of
neck.
Also the carotid pulse is palpating and rythem
Hair: the hair is dark in color , very short . pt complain of loss of hair due to
falling down of hair because pt taken chemotherapy .
Mild dry in textur hair , mild quality .
Eyes : the eyes are black in color , symmetry , equal movement of the
pupils , round and equal .
The space between eyes normal and is about 4.5cm .
When do exam the eyes by ophthalmoscope , the pt eyes good reaction to the
light , and no any irregularities , good visual acuity when asked pt to read
some words .
The eye lids closed and open completely , no any infection or irritation
present , no edema or mobility and no signs of marginal blepharitis .
The sclera is white in color , no nodules or swelling .
The eyes brow symmetry , dark in color .
The conjunctiva pink in color , no inflammation.
Vasodilator occur to the pupils of eyes when assess the pupils by
opthalmoscope when remove the light , and vasoconstriction pupils occur
when apply the light.
Ears: When inspect of the external auditory structures and used otoscope to
examine internal ear observes the ear symmetry , the pinna is on a horisantal
level with outer canthus of eyes , not flattened , in good hygiene , no
inflammation was observed of tympanic membrane , or any drain of pus, no
lesion or deformity, and it is pink in color.
Hearing acuity :
I call the child from distance area, and the response of pt answer me well
after he hearing my voice and I was observe good hearing acuity
Mouth & Throat: The lips pink in color and symmetry , moisture, no any
cracking or ulcer .
The mucosa lining is pink in color , pt complain of stomatitis and teeth
decay due to chemotherapy. The mother was encouraged to give pt adequate
fluid intake , and suggest smaller , more frequent meal , low salt diet , and
encouraged frequent oral hygiene .
Good mouth hygiene , no bad odor .
The tonsilse : no evidence of pus , swelling , ulceration or tonsillar
enlargement .
The tongue : no hardening when palpate.
Abdomen
The abdominal shape normally and is cylindrical .
When assess the abdomen and inspection soft lax , no tenderness, mass, or
pain .
Good abdominal skin integrity , and umbilical hernia was appearance .
No localized abdominal distention .
G.I.T
The bowel sound was hearing by stethoscope and was available .
Child complain of nausea and big amount of vomiting , yellow in color
when asked the mother about vomiting .
Pt complain of nausea due to chemotherapy, and loss of appitite was
observed .
The habbite of deffication is every day pass stool brown in color and soft,
moderate in amount, no diarrhea or abdominal distention .
Genitalia
Anus : around the sphincter anus seen skin irritation and inflammation ,
redness in color due to pyrexia before 2day and chemotherapy .
The inguinal and femoral area normal, no any bluges or suggest a hernia.
Fine motor :
This exam done by ask pt to grasp pencil and he writes his name and plant
his house and he did that.
Has good fine motor skills.
Gross motor :
Pt able to draft his house and bus, and he can race and run.
Has good gross motor function.
Sensation :
Visual acuity : has good visual acuity when asked to read some words .
hearing acuity : has good hearing acuity when try to call him from distance
area and he response to me quickly.
Smelling acuity : pt can enable to use our sense of smelling.
Child can distinguish between cold and hot, and has good reflex when assess
by touch the skin pt by tip of pin and he withdrow his finger quickly.
Child also can distinguish between diffrensial tastes.
Lymph Nodes
No palpated any lymph nodes during assessment in the neck or all of our
body area and used distal part of my finger when assess.
Name of
Route Dose Action Side Effect
Drug
Aderiamycin IV 30 mg antineoplasmic chemotherapy drug, 1.nausea and vomiting
3 doses for work by damaging DNA and RNA, 2.low blood counts,
3week. that tells the cell how to copy it self WBC,RBC,PLT, may
in division. If the cells are unable to temporarily decrease
divide they die. The faster cells are 3.mouth sores and
dividing, the more likely it is that stomatitis.
chemotherapy will kill the cells, 4.loss of hair.
causing the tumor to shrink. 5.changein color of
urine may appear red
or orange.
Kidrolase IV / IM 7000 unit . Chemotherapy drug anticancer, this 1.fever
Other name 8 doses for medication classified as an enzyme. 2.nausea and vomiting
Asparaginase every other All cells need a chemical called 3.stomach cramping
day. asparagines to stay alive, normally 4.poor appetite
cell can make this chemical for 5.allergic reaction like,
themselves, while cancer cells itching, rash, and face
cannot, asparagines break down swelling .
asparagine , they die.
Vincristine IV 1.5gm Chemotherapy drug, anticancer, 1.hair loss
3 doses for classified as a plant alkaloid. drug, 2.nausea and vomiting
3week work by damaging DNA and RNA, 3.constipation
that tells the cell how to copy it self 4.low blood count
in division. If the cells are unable to 5.weight loss
divide they die. The faster cells are 6.stomatitis
dividing, the more likely it is that
chemotherapy will kill the cells,
causing the tumor to shrink.
Rocephin IV /IM 500mg twice It work by fighting bacterial in body 1.diarrhea that watery
Other name daily IV {antibiotic } or bloody
ceftriaxone It work to inhibetor the protein 2.fever or chills
synthesis or cell wall. 3.skin rash
Nausea and vomiting
4.headache and
dizziness
Gentamycin IV diluted or 40mg twice It is active against some gram 1.difficulty hearing
Other name IM daily IV positive and money gram negative 2.dizziness
Aminoglycoside organisms , like E. coli , klebsiella , 3.increased thirst
Antibiotic pseudomonas, and treat serious 4.pain or difficulty
infection caused by this bacteria passing urine .
Hydrocortisone IV 50mg twice Hydrocortison prevents the release 1.swelling rapid weight
daily of substance in the body that cause gain, feeling short of
inflammation . used to treat many breathing.
different conditions such as allergic 2.problem with vision
disorder, skin conditions, or 3.sleep problem.
breathing disorders 4.dry skin, acne
5.slow wound healing
ZOFRAN IV 32mg Zofran used to prevent nausea and 1. blurred vision.
{SETRON} vomiting that caused by surgery or 2.slow heart rate.
by medicine to treat cancer 3.anxiety and agitation.
{chemotherapy or radiation}, given 4. Shivering.
before 30minutes of chemotherapy.
RATIDINE IV 25mg twice Is group of drug called a histamine - 1.chest pain, fever.
daily 2bllocker. Work by reducing the 2.unusual weakness.
amount of acid in stomach produces 3.fast or slow heart rate
Use to prevent ulcer in the stomach 4.problems vision.
and intestines.
ZYLORIC TAB 1/2 tab 3 time Zyloric tab belong to a group of 1.high fever.
daily. 100mg medicines called enzyme inhibitors, 2.joint pain.
which act to control the speed at 3.nausea and vomiting.
which special chemical changes 4.jaundice.
occure in the body. They are used to 5.chest pain, high
prevent gout and other conditions blood pressure.
associated with excess uric acid in 6.feeling thirst, tired,
the body ,including kidney stones and losing weight.
and certain types of kidney diseases.
VIII. Pathophysiology of the disease: (10 points)
Definition:
Acute lymphocytic leukemia (ALL) is a type of cancer of the blood and
bone marrow — the spongy tissue inside bones where blood cells are made.
Pathophysiology:
Bone marrow cell develops errors in its DNA. the errors tell the cell to
continue growing and dividing rapidly blood cell production goes awry.
The bone marrow produces immature cells that develop into leukemic white
blood cells called lymphoblasts. These abnormal cells are unable to function
properly, and they can build up and crowd out healthy cells.
S+S:
Signs and symptoms of acute lymphocytic leukemia may include:
Bleeding from the gums
Fever
Frequent infections
Frequent or severe nosebleeds
Loss of appetite
Lumps caused by swollen lymph nodes in and around the neck,
underarm, stomach or groin
Pale skin
Shortness of breath
Weight loss
Weakness, fatigue or a general decrease in energy