Nursing

Generic Name Indications Contraindications Mechanism of Action Side Effect

Responsibilities
Midazolam PO: CHILDREN: Acute narrow- Enhances action of Frequent (10%–4%): • Obtain vital signs
0.25–0.5 mg/kg. angle gamma-aminobutyric Decreased respiratory before
glaucoma, acid (GABA), one of rate, tenderness at administration.
IV: ADULTS, ELDERLY: allergies to the major inhibitory IM or IV injection site,
0.02–0.04 mg/kg. cherries (syrup), neurotransmitters in pain during injection, • Before
CHILDREN 6–12 YRS: coma, shock. the brain. oxygen desaturation, administering,
0.025–0.05 mg/kg. hiccups. have oxygen and
CHILDREN 6 MOS–5 Produces anxiolytic, Occasional (3%–2%): resuscitation
YRS: 0.05–0.1 mg/kg. hypnotic, Hypotension, equipment
anticonvulsant, muscle paradoxical CNS available in case
IM: ADULTS, ELDERLY: relaxant, reaction. of severe
Classification 0.07–0.08 mg/kg amnestic effects. Rare (less than 2%): respiratory
30–60 min before Nausea, vomiting, depression.
Sedative, surgery. headache, coughing.
Anxiolytic Usual dose: 5 mg. • Monitor blood
pressure and
CHILDREN: oxygen
0.1–0.15 mg/kg 30– saturation.
60 min before
surgery. • Monitor and
Maximum:10 mg record patient
response to
medication and
level of sedation.