DEPARTMENT OF PHARMACOLOGY AND THERAPEUTICS

LECTURE SCHEDULE, THIRD YEAR SEMESTER 1, 2023/2024 ACADEMIC YEAR

MBCHB, BPHARM, PHS, BNS, BNC & MLS

Course Name: CHEMOTHERAPY, CYTOTOXIC AGENTS AND IMMUNOPHARMACOLOGY

Course code: PHA 3111.

Date Topics Lecturer

03/10/2023 Introduction to antimicrobial agents: empiric therapy; principles of antimicrobial therapy Daniel Chans
04/10/2023 Beta-lactam antibiotics: penicillins cephalosparins, monobactams Beta-lactamase Daniel Chans
inhibitors, carbapenems
10/10/2023 Aminolglycosides, spectinomycin, clindamycin & streptogramins Daniel Chans

11/10/2023 Sulfonamides, trimethoprim & quinolones Daniel Chans

17/10/2023 Antimycobacterial drugs - Mycobacterium TB, leprae & atypical mycobacterial agents Didas Mwebesa

18/10/2023 Antifungal drugs Didas Mwebesa

24/10/2023 Viral replication & sites of antiviral drug action. Antiherpes drugs Joseph Oloro

25/10/2023 HIV replication cycles. Drugs used to treat HIV. Misc. antiviral agents Joseph Oloro

31/10/2023 Miscellaneous antimicrobial agents, disinfectants, antiseptics Daniel Chans

01/11/2023 Principles governing the use of antimicrobial drugs. Empirical therapy, Therapy of Joseph Oloro
infections with known etiology, monitoring therapeutic response
07/11/2023 Antimicrobial pharmacodynamics & pharmacokinetics. Management of antimicrobial Daniel Chans
agent toxicity, antimicrobial agent combinations
08/11/2023 Antimicrobial prophylaxis Joseph Oloro

15/11/2023 MID-SEMESTER EXAMINATIONS All members of staff &

Masters Students
21/11/2023 Anti-parasitic drugs: Malaria Dr. Martin Amanya

22/11/2023 Anti-parasitic drugs: Nematodes, trematodes & cestodes Dr. Martin Amanya

28/11/2023 Anti-parasitic drugs: Amebiasis, giardiasis Dr. Martin Amanya

29/11/2023 Cancer chemotherapy I: Cell cycle kinetics, alkylating agents, antimetabolites Didas Mwebesa

05/12/2023 Cancer chemotherapy II: alkaloids, antibiotics, hormonal agents Didas Mwebesa

06/12/2023 Immunmodulating agents & Immunotherapy Silvano Twinomujuni

12/12/2023 Student Seminars: Disinfection & autoclaving (demonstration & practicum) Didas Mwebesa

13/12/2023 Student Seminars: Monitoring therapeutic responses to antibiotics (seminar) Daniel Chans

19/12/2023 Student Seminars: Current treatment guidelines on HIV, TB etc. (seminar) Joseph Oloro

20/12/2023 Student Seminars: Current treatment guidelines on Malaria, etc. (seminar) Dr. Martin Amanya

05/1/2024 END OF SEMESTER EXAMS All members of staff &

Masters Students
1
Recommended text and reference books

1. Basic & Clinical Pharmacology, by Bertram G. Katzung

2. Clinical Pharmacology, by D.R. Laurence & P.N. Bennet
3. Goodman & Gilman’s The Pharmacological Basis of Therapeutics (12th Ed). McGraw Hill
Edited by Brunton, L.L. et al., (2011).
4. Rang and Dale’s Pharmacology (7th Ed.) Elsevier, by Rang, H.P. et al., (2010).
5. Katzung & Trevor’s Pharmacology Examination and Board Reviews (9th Edn) McGraw Hill,
edited by Trevor, A.J. et al., (2010).
6. Board Review Series (Pharmacology). (4th or 5th Edn), by Rosenfeld,G.C., (2007).
Lippincott Williams & Wilkins.
7. Netter’s Illustrated Pharmacology – International Student Edition (1st edition), by Raffa
R.B. et al (2005). Icon Learning Systems.

Lecture hours:

Tuesday 4– 6 p.m.
Wednesday 2 – 4 p.m.

Venue: Pathology Laboratory for Face-to-Face Lectures OR Online via zoom